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    Robert Oshima

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentPathology
    Address9500 Gilman Drive #0612
    CA La Jolla 92093
    Phone858-646-3147
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Tumor repressive role of Ets2 in the intestine
      NIH/NIDDK R01DK092084Sep 30, 2010 - Aug 31, 2013
      Role: Principal Investigator
      An Ets2 dependent stromal restriction of breast cancer
      NIH/NCI R01CA098778Jan 1, 2003 - Dec 31, 2007
      Role: Principal Investigator
      Ets Transcription Factors in Development and Cancer
      NIH/NCI R01CA074547Jun 2, 1997 - Mar 31, 2005
      Role: Principal Investigator
      DEVELOPMENTAL CONTROL OF CYTOKERATIN EXPRESSION
      NIH/NCI R01CA042302May 1, 1986 - Dec 31, 2003
      Role: Principal Investigator
      DEVELOPMENTAL GENE REGULATION
      NIH/NCI T32CA009497Sep 1, 1984 - Aug 31, 1990
      Role: Principal Investigator
      TERATOCARCINOMA CYTOSKELETAL PROTEINS
      NIH/NCI R01CA033946Jun 1, 1982 - Aug 31, 1989
      Role: Principal Investigator
      CHROMATIN PROTEINS OF EMBRYONAL CARCINOMA CELLS
      NIH/NCI R01CA033011Feb 1, 1982 - Jan 31, 1986
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Strietz J, Stepputtis SS, Preca BT, Vannier C, Kim MM, Castro DJ, Au Q, Boerries M, Busch H, Aza-Blanc P, Heynen-Genel S, Bronsert P, Kuster B, Stickeler E, Brabletz T, Oshima R, Maurer J. ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer. Oncotarget. 2016 Dec 13; 7(50):83278-83293. PMID: 27829216.
        View in: PubMed
      2. John S, Russell L, Chin SS, Luo W, Oshima R, Garrett-Sinha LA. Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation. Mol Cell Biol. 2014 Feb; 34(3):522-32. PMID: 24277931; PMCID: PMC3911503.
      3. Castro DJ, Maurer J, Hebbard L, Oshima R. ROCK1 inhibition promotes the self-renewal of a novel mouse mammary cancer stem cell. Stem Cells. 2013 Jan; 31(1):12-22. PMID: 22961723; PMCID: PMC3967738.
      4. Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima R, Willerson JT, Potaman VN, Schwartz RJ. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):13016-21. PMID: 22826236; PMCID: PMC3420197.
      5. Xia Z, Correa RG, Das JK, Farhana L, Castro DJ, Yu J, Oshima R, Fontana JA, Reed JC, Dawson MI. Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of leukemia and cancer cell lines. J Med Chem. 2012 Jan 12; 55(1):233-49. PMID: 22136251.
        View in: PubMed
      6. Xia Z, Farhana L, Correa RG, Das JK, Castro DJ, Yu J, Oshima R, Reed JC, Fontana JA, Dawson MI. Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. J Med Chem. 2011 Jun 09; 54(11):3793-816. PMID: 21548569.
        View in: PubMed
      7. Múnera J, Ceceña G, Jedlicka P, Wankell M, Oshima R. Ets2 regulates colonic stem cells and sensitivity to tumorigenesis. Stem Cells. 2011 Mar; 29(3):430-9. PMID: 21425406; PMCID: PMC3339631.
      8. Hebbard LW, Maurer J, Miller A, Lesperance J, Hassell J, Oshima R, Terskikh AV. Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo. Cancer Res. 2010 Nov 01; 70(21):8863-73. PMID: 20861186; PMCID: PMC3990264.
      9. Hebbard L, Cecena G, Golas J, Sawada J, Ellies LG, Charbono A, Williams R, Jimenez RE, Wankell M, Arndt KT, DeJoy SQ, Rollins RA, Diesl V, Follettie M, Chen L, Rosfjord E, Cardiff RD, Komatsu M, Boschelli F, Oshima R. Control of mammary tumor differentiation by SKI-606 (bosutinib). Oncogene. 2011 Jan 20; 30(3):301-12. PMID: 20818417; PMCID: PMC3000443.
      10. Cheng L, Guo J, Sun L, Fu J, Barnes PF, Metzger D, Chambon P, Oshima R, Amagai T, Su DM. Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy. J Biol Chem. 2010 Feb 19; 285(8):5836-47. PMID: 19955175; PMCID: PMC2820809.
      11. Morioka Y, Isotani A, Oshima R, Okabe M, Ikawa M. Placenta-specific gene activation and inactivation using integrase-defective lentiviral vectors with the Cre/LoxP system. Genesis. 2009 Dec; 47(12):793-8. PMID: 19830817.
        View in: PubMed
      12. Wei G, Srinivasan R, Cantemir-Stone CZ, Sharma SM, Santhanam R, Weinstein M, Muthusamy N, Man AK, Oshima R, Leone G, Ostrowski MC. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 2009 Jul 30; 114(5):1123-30. PMID: 19411629; PMCID: PMC2721789.
      13. Maurer J, Nelson B, Ceceña G, Bajpai R, Mercola M, Terskikh A, Oshima R. Contrasting expression of keratins in mouse and human embryonic stem cells. PLoS One. 2008; 3(10):e3451. PMID: 18941637; PMCID: PMC2565505.
      14. Jaksch M, Múnera J, Bajpai R, Terskikh A, Oshima R. Cell cycle-dependent variation of a CD133 epitope in human embryonic stem cell, colon cancer, and melanoma cell lines. Cancer Res. 2008 Oct 01; 68(19):7882-6. PMID: 18829544; PMCID: PMC2561223.
      15. Toivola DM, Nakamichi I, Strnad P, Michie SA, Ghori N, Harada M, Zeh K, Oshima R, Baribault H, Omary MB. Keratin overexpression levels correlate with the extent of spontaneous pancreatic injury. Am J Pathol. 2008 Apr; 172(4):882-92. PMID: 18349119; PMCID: PMC2276414.
      16. Hebbard LW, Garlatti M, Young LJ, Cardiff RD, Oshima R, Ranscht B. T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model. Cancer Res. 2008 Mar 01; 68(5):1407-16. PMID: 18316604; PMCID: PMC2676344.
      17. Kairouz-Wahbe R, Biliran H, Luo X, Khor I, Wankell M, Besch-Williford C, Pascual J, Oshima R, Ruoslahti E. Anoikis effector Bit1 negatively regulates Erk activity. Proc Natl Acad Sci U S A. 2008 Feb 05; 105(5):1528-32. PMID: 18218778; PMCID: PMC2234178.
      18. Vervoort VS, Lu M, Valencia F, Lesperance J, Breier G, Oshima R, Pasquale EB. A novel Flk1-TVA transgenic mouse model for gene delivery to angiogenic vasculature. Transgenic Res. 2008 Jun; 17(3):403-15. PMID: 18027100.
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      19. Wen F, Tynan JA, Cecena G, Williams R, Múnera J, Mavrothalassitis G, Oshima R. Ets2 is required for trophoblast stem cell self-renewal. Dev Biol. 2007 Dec 01; 312(1):284-99. PMID: 17977525; PMCID: PMC2211385.
      20. Allen SD, Garrett JT, Rawale SV, Jones AL, Phillips G, Forni G, Morris JC, Oshima R, Kaumaya PT. Peptide vaccines of the HER-2/neu dimerization loop are effective in inhibiting mammary tumor growth in vivo. J Immunol. 2007 Jul 01; 179(1):472-82. PMID: 17579068.
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      21. Papadaki C, Alexiou M, Cecena G, Verykokakis M, Bilitou A, Cross JC, Oshima R, Mavrothalassitis G. Transcriptional repressor erf determines extraembryonic ectoderm differentiation. Mol Cell Biol. 2007 Jul; 27(14):5201-13. PMID: 17502352; PMCID: PMC1951951.
      22. Oshima R. Intermediate filaments: a historical perspective. Exp Cell Res. 2007 Jun 10; 313(10):1981-94. PMID: 17493611; PMCID: PMC1950476.
      23. Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima R, Feng GS. Role of Gab2 in mammary tumorigenesis and metastasis. Oncogene. 2007 Jul 26; 26(34):4951-60. PMID: 17310989.
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      24. Okada Y, Ueshin Y, Isotani A, Saito-Fujita T, Nakashima H, Kimura K, Mizoguchi A, Oh-Hora M, Mori Y, Ogata M, Oshima R, Okabe M, Ikawa M. Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer. Nat Biotechnol. 2007 Feb; 25(2):233-7. PMID: 17220877.
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      25. Vervoort VS, Roselli S, Oshima R, Pasquale EB. Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling. Gene. 2007 Apr 15; 391(1-2):161-70. PMID: 17270363; PMCID: PMC1876674.
      26. Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima R, Muller WJ, Feng GS. Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation. J Biol Chem. 2006 Nov 10; 281(45):34374-80. PMID: 16959766; PMCID: PMC1761121.
      27. Cecena G, Wen F, Cardiff RD, Oshima R. Differential sensitivity of mouse epithelial tissues to the polyomavirus middle T oncogene. Am J Pathol. 2006 Jan; 168(1):310-20. PMID: 16400032; PMCID: PMC1592648.
      28. Nakamichi I, Toivola DM, Strnad P, Michie SA, Oshima R, Baribault H, Omary MB. Keratin 8 overexpression promotes mouse Mallory body formation. J Cell Biol. 2005 Dec 19; 171(6):931-7. PMID: 16365160; PMCID: PMC2171301.
      29. Tynan JA, Wen F, Muller WJ, Oshima R. Ets2-dependent microenvironmental support of mouse mammary tumors. Oncogene. 2005 Oct 20; 24(46):6870-6. PMID: 16007139.
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      30. Liu M, Howes A, Lesperance J, Stallcup WB, Hauser CA, Kadoya K, Oshima R, Abraham RT. Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer. Cancer Res. 2005 Jun 15; 65(12):5325-36. PMID: 15958580.
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      31. Wei G, Guo J, Doseff AI, Kusewitt DF, Man AK, Oshima R, Ostrowski MC. Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model. J Immunol. 2004 Jul 15; 173(2):1374-9. PMID: 15240733.
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      32. Oshima R, Lesperance J, Munoz V, Hebbard L, Ranscht B, Sharan N, Muller WJ, Hauser CA, Cardiff RD. Angiogenic acceleration of Neu induced mammary tumor progression and metastasis. Cancer Res. 2004 Jan 01; 64(1):169-79. PMID: 14729621.
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      33. Galang CK, Muller WJ, Foos G, Oshima R, Hauser CA. Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors. J Biol Chem. 2004 Mar 19; 279(12):11281-92. PMID: 14662758.
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      34. Man AK, Young LJ, Tynan JA, Lesperance J, Egeblad M, Werb Z, Hauser CA, Muller WJ, Cardiff RD, Oshima R. Ets2-dependent stromal regulation of mouse mammary tumors. Mol Cell Biol. 2003 Dec; 23(23):8614-25. PMID: 14612405; PMCID: PMC262691.
      35. Hevér A, Oshima R, Hauser CA. Ets2 is not required for Ras or Neu/ErbB-2 mediated cellular transformation in vitro. Exp Cell Res. 2003 Oct 15; 290(1):132-43. PMID: 14516794.
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      36. Jaquemar D, Kupriyanov S, Wankell M, Avis J, Benirschke K, Baribault H, Oshima R. Keratin 8 protection of placental barrier function. J Cell Biol. 2003 May 26; 161(4):749-56. PMID: 12771125; PMCID: PMC2199358.
      37. Wen F, Cecena G, Munoz-Ritchie V, Fuchs E, Chambon P, Oshima R. Expression of conditional cre recombinase in epithelial tissues of transgenic mice. Genesis. 2003 Feb; 35(2):100-6. PMID: 12533792; PMCID: PMC2405925.
      38. Lee JC, Schickling O, Stegh AH, Oshima R, Dinsdale D, Cohen GM, Peter ME. DEDD regulates degradation of intermediate filaments during apoptosis. J Cell Biol. 2002 Sep 16; 158(6):1051-66. PMID: 12235123; PMCID: PMC2173221.
      39. Oshima R. Apoptosis and keratin intermediate filaments. Cell Death Differ. 2002 May; 9(5):486-92. PMID: 11973607.
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      40. Cardiff RD, Bern HA, Faulkin LJ, Daniel CW, Smith GH, Young LJ, Medina D, Gardner MB, Wellings SR, Shyamala G, Guzman RC, Rajkumar L, Yang J, Thordarson G, Nandi S, MacLeod CL, Oshima R, Man AK, Sawai ET, Gregg JP, Cheung AT, Lau DH. Contributions of mouse biology to breast cancer research. Comp Med. 2002 Feb; 52(1):12-31. PMID: 11900409.
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      41. Dankort D, Maslikowski B, Warner N, Kanno N, Kim H, Wang Z, Moran MF, Oshima R, Cardiff RD, Muller WJ. Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer. Mol Cell Biol. 2001 Mar; 21(5):1540-51. PMID: 11238891; PMCID: PMC86700.
      42. Tamai Y, Ishikawa T, Bösl MR, Mori M, Nozaki M, Baribault H, Oshima R, Taketo MM. Cytokeratins 8 and 19 in the mouse placental development. J Cell Biol. 2000 Oct 30; 151(3):563-72. PMID: 11062258; PMCID: PMC2185583.
      43. Caulin C, Ware CF, Magin TM, Oshima R. Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis. J Cell Biol. 2000 Apr 03; 149(1):17-22. PMID: 10747083; PMCID: PMC2175089.
      44. Willoughby DA, Vilalta A, Oshima R. An Alu element from the K18 gene confers position-independent expression in transgenic mice. J Biol Chem. 2000 Jan 14; 275(2):759-68. PMID: 10625605.
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      45. Neznanov N, Man AK, Yamamoto H, Hauser CA, Cardiff RD, Oshima R. A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice. Cancer Res. 1999 Sep 01; 59(17):4242-6. PMID: 10485465.
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      46. Rhodes K, Oshima R. A regulatory element of the human keratin 18 gene with AP-1-dependent promoter activity. J Biol Chem. 1998 Oct 09; 273(41):26534-42. PMID: 9756890.
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      47. Yamamoto H, Flannery ML, Kupriyanov S, Pearce J, McKercher SR, Henkel GW, Maki RA, Werb Z, Oshima R. Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev. 1998 May 01; 12(9):1315-26. PMID: 9573048; PMCID: PMC316781.
      48. Suzuki N, Zara J, Sato T, Ong E, Bakhiet N, Oshima R, Watson KL, Fukuda MN. A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):5027-32. PMID: 9560222; PMCID: PMC20207.
      49. Neznanov N, Umezawa A, Oshima R. A regulatory element within a coding exon modulates keratin 18 gene expression in transgenic mice. J Biol Chem. 1997 Oct 31; 272(44):27549-57. PMID: 9346889.
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      50. Caulín C, Salvesen GS, Oshima R. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis. J Cell Biol. 1997 Sep 22; 138(6):1379-94. PMID: 9298992; PMCID: PMC2132555.
      51. Umezawa A, Yamamoto H, Rhodes K, Klemsz MJ, Maki RA, Oshima R. Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression. Mol Cell Biol. 1997 Sep; 17(9):4885-94. PMID: 9271368; PMCID: PMC232341.
      52. Pankov R, Simcha I, Zöller M, Oshima R, Ben-Ze'ev A. Contrasting effects of K8 and K18 on stabilizing K19 expression, cell motility and tumorigenicity in the BSp73 adenocarcinoma. J Cell Sci. 1997 Apr; 110 ( Pt 8):965-74. PMID: 9152022.
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      53. Oshima R, Baribault H, Caulín C. Oncogenic regulation and function of keratins 8 and 18. Cancer Metastasis Rev. 1996 Dec; 15(4):445-71. PMID: 9034603.
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      54. Henkel GW, McKercher SR, Yamamoto H, Anderson KL, Oshima R, Maki RA. PU.1 but not ets-2 is essential for macrophage development from embryonic stem cells. Blood. 1996 Oct 15; 88(8):2917-26. PMID: 8874188.
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      55. Ku NO, Michie SA, Soetikno RM, Resurreccion EZ, Broome RL, Oshima R, Omary MB. Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant. J Clin Invest. 1996 Aug 15; 98(4):1034-46. PMID: 8770877; PMCID: PMC507520.
      56. Galang CK, García-Ramírez J, Solski PA, Westwick JK, Der CJ, Neznanov NN, Oshima R, Hauser CA. Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation. J Biol Chem. 1996 Apr 05; 271(14):7992-8. PMID: 8626480.
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      57. Neznanov N, Kohwi-Shigematsu T, Oshima R. Contrasting effects of the SATB1 core nuclear matrix attachment region and flanking sequences of the keratin 18 gene in transgenic mice. Mol Biol Cell. 1996 Apr; 7(4):541-52. PMID: 8730098; PMCID: PMC275908.
      58. Ku NO, Michie S, Oshima R, Omary MB. Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol. 1995 Dec; 131(5):1303-14. PMID: 8522591; PMCID: PMC2120631.
      59. Coll JL, Ben-Ze'ev A, Ezzell RM, Rodríguez Fernández JL, Baribault H, Oshima R, Adamson ED. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9161-5. PMID: 7568093; PMCID: PMC40944.
      60. Pankov R, Neznanov N, Umezawa A, Oshima R. AP-1, ETS, and transcriptional silencers regulate retinoic acid-dependent induction of keratin 18 in embryonic cells. Mol Cell Biol. 1994 Dec; 14(12):7744-57. PMID: 7526151; PMCID: PMC359315.
      61. Pankov R, Umezawa A, Maki R, Der CJ, Hauser CA, Oshima R. Oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway. Proc Natl Acad Sci U S A. 1994 Feb 01; 91(3):873-7. PMID: 7508123; PMCID: PMC521414.
      62. Thorey IS, Meneses JJ, Neznanov N, Kulesh DA, Pedersen RA, Oshima R. Embryonic expression of human keratin 18 and K18-beta-galactosidase fusion genes in transgenic mice. Dev Biol. 1993 Dec; 160(2):519-34. PMID: 7504637.
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      63. Thorey IS, Ceceña G, Reynolds W, Oshima R. Alu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic mice. Mol Cell Biol. 1993 Nov; 13(11):6742-51. PMID: 7692231; PMCID: PMC364737.
      64. Baribault H, Price J, Miyai K, Oshima R. Mid-gestational lethality in mice lacking keratin 8. Genes Dev. 1993 Jul; 7(7A):1191-202. PMID: 7686525.
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      65. Chu YW, Runyan RB, Oshima R, Hendrix MJ. Expression of complete keratin filaments in mouse L cells augments cell migration and invasion. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):4261-5. PMID: 7683431; PMCID: PMC46486.
      66. Neznanov N, Thorey IS, Ceceña G, Oshima R. Transcriptional insulation of the human keratin 18 gene in transgenic mice. Mol Cell Biol. 1993 Apr; 13(4):2214-23. PMID: 7681143; PMCID: PMC359542.
      67. Neznanov NS, Oshima R. cis regulation of the keratin 18 gene in transgenic mice. Mol Cell Biol. 1993 Mar; 13(3):1815-23. PMID: 7680099; PMCID: PMC359494.
      68. Oshima R, Baribault H. Inactivation of keratin genes by gene targeting: a perspective. J Dermatol. 1992 Nov; 19(11):786-9. PMID: 1284072.
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      69. Thorey IS, Pedersen RA, Linney E, Oshima R. Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice. Dev Dyn. 1992 Oct; 195(2):100-12. PMID: 1284293.
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      70. Oshima R. Single-stranded DNA binding protein facilitates amplification of genomic sequences by PCR. Biotechniques. 1992 Aug; 13(2):188. PMID: 1382464.
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      71. Oshima R. Intermediate filament molecular biology. Curr Opin Cell Biol. 1992 Feb; 4(1):110-6. PMID: 1373066.
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      72. Kwon M, Oshima R. JunB does not inhibit the induction of c-Jun during the retinoic acid induced differentiation of F9 cells. Dev Dyn. 1992 Feb; 193(2):193-8. PMID: 1581607.
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      73. Baribault H, Oshima R. Polarized and functional epithelia can form after the targeted inactivation of both mouse keratin 8 alleles. J Cell Biol. 1991 Dec; 115(6):1675-84. PMID: 1721911; PMCID: PMC2289210.
      74. Abe M, Oshima R. A single human keratin 18 gene is expressed in diverse epithelial cells of transgenic mice. J Cell Biol. 1990 Sep; 111(3):1197-206. PMID: 1697294; PMCID: PMC2116298.
      75. Oshima R, Abrams L, Kulesh D. Activation of an intron enhancer within the keratin 18 gene by expression of c-fos and c-jun in undifferentiated F9 embryonal carcinoma cells. Genes Dev. 1990 May; 4(5):835-48. PMID: 1696235.
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      76. Kulesh DA, Oshima R. Complete structure of the gene for human keratin 18. Genomics. 1989 Apr; 4(3):339-47. PMID: 2469635.
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      77. Kulesh DA, Ceceña G, Darmon YM, Vasseur M, Oshima R. Posttranslational regulation of keratins: degradation of mouse and human keratins 18 and 8. Mol Cell Biol. 1989 Apr; 9(4):1553-65. PMID: 2471065; PMCID: PMC362572.
      78. Oshima R. Rapid identification of M13 phage deletions for sequence analysis. Biotechniques. 1988 Jun; 6(6):510-1. PMID: 3273183.
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      79. Oshima R, Trevor K, Shevinsky LH, Ryder OA, Ceceña G. Identification of the gene coding for the Endo B murine cytokeratin and its methylated, stable inactive state in mouse nonepithelial cells. Genes Dev. 1988 May; 2(5):505-16. PMID: 2454868.
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      80. Kulesh DA, Oshima R. Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells. Mol Cell Biol. 1988 Apr; 8(4):1540-50. PMID: 2454392; PMCID: PMC363314.
      81. Howe WE, Klier FG, Oshima R. Murine endodermal cytokeratins Endo A and Endo B are localized in the same intermediate filament. J Histochem Cytochem. 1986 Jun; 34(6):785-93. PMID: 2422254.
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      82. Singer PA, Trevor K, Oshima R. Molecular cloning and characterization of the Endo B cytokeratin expressed in preimplantation mouse embryos. J Biol Chem. 1986 Jan 15; 261(2):538-47. PMID: 2416755.
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      83. Oshima R, Millán JL, Ceceña G. Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation. Differentiation. 1986; 33(1):61-8. PMID: 2434380.
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      84. Trevor K, Oshima R. Preimplantation mouse embryos and liver express the same type I keratin gene product. J Biol Chem. 1985 Dec 15; 260(29):15885-91. PMID: 2415524.
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      85. Engvall E, Oshima R, Brennan MJ, Ruoslahti E. Clonal tumorigenic endodermal cell lines producing basement membrane components. Exp Cell Res. 1984 Jan; 150(1):258-67. PMID: 6692849.
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      86. Oshima R, Howe WE, Klier FG, Adamson ED, Shevinsky LH. Intermediate filament protein synthesis in preimplantation murine embryos. Dev Biol. 1983 Oct; 99(2):447-55. PMID: 6352374.
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      87. Grover A, Oshima R, Adamson ED. Epithelial layer formation in differentiating aggregates of F9 embryonal carcinoma cells. J Cell Biol. 1983 Jun; 96(6):1690-6. PMID: 6343402; PMCID: PMC2112462.
      88. Tabor JM, Oshima R. Identification of mRNA species that code for extra-embryonic endodermal cytoskeletal proteins in differentiated derivatives of murine embryonal carcinoma cells. J Biol Chem. 1982 Aug 10; 257(15):8771-4. PMID: 7201471.
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      89. Lennox RW, Oshima R, Cohen LH. The H1 histones and their interphase phosphorylated states in differentiated and undifferentiated cell lines derived from murine teratocarcinomas. J Biol Chem. 1982 May 10; 257(9):5183-9. PMID: 7068681.
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      90. Oshima R. Developmental expression of murine extra-embryonic endodermal cytoskeletal proteins. J Biol Chem. 1982 Apr 10; 257(7):3414-21. PMID: 6174520.
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      91. Howe WE, Oshima R. Coordinate expression of parietal endodermal functions in hybrids of embryonal carcinoma and endodermal cells. Mol Cell Biol. 1982 Mar; 2(3):331-7. PMID: 7202115; PMCID: PMC369792.
      92. Ritchie DG, Jonas AJ, Oshima R, Neal P, Schneider JA. Cystinotic fibroblasts are depleted of free-cystine by acid pH medium. Pediatr Res. 1981 Dec; 15(12):1492-4. PMID: 7322669.
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      93. Oshima R, McKerrow J, Cox D. Murine embryonal carcinoma hybrids: decreased ability to spontaneously differentiate as a dominant trait. J Cell Physiol. 1981 Nov; 109(2):195-204. PMID: 7197684.
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