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    Paul Price

    TitleEmeritus Professor
    SchoolUniversity of California, San Diego
    DepartmentMolecular Biology
    Address9500 Gilman Drive #0368
    CA La Jolla 92093
    Phone858-534-2120
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      Collapse Research 
      Collapse Research Activities and Funding
      Initiation and Inhibition of Medial Artery Calcification
      NIH/NHLBI R01HL058090Jul 1, 1998 - Nov 30, 2010
      Role: Principal Investigator
      FUNCTION OF THE VITAMIN K-DEPENDENT BONE PROTEIN
      NIH/NIAMS R37AR027029May 1, 1980 - Apr 30, 1997
      Role: Principal Investigator
      FUNCTION OF THE VITAMIN K-DEPENDENT BONE PROTEIN
      NIH/NIAMS R01AR027029May 1, 1980 - Apr 30, 1991
      Role: Principal Investigator
      FUNCTION OF THE VITAMIN K DEPENDENT BONE PROTEIN
      NIH/NIADDK R01AM027029May 1, 1980 - Apr 30, 1986
      Role: Principal Investigator
      MATRIX GLA PROTEIN AND CARTILAGE CALCIFICATION
      NIH/NIAMS R01AR025921Jul 1, 1979 - Jun 30, 2003
      Role: Principal Investigator
      A NOVEL MARKER FOR BONE METABOLISM
      NIH/NIADDK R01AM025921Jul 1, 1979 - Nov 30, 1985
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Acharya B, Head GP, Price P, Huang F. Fitness costs and inheritance of Cry2Ab2 resistance in Spodoptera frugiperda (J.E. Smith). J Invertebr Pathol. 2017 Oct; 149:8-14. PMID: 28676378.
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      2. Yang F, Kerns DL, Head GP, Price P, Huang F. Cross-resistance to purified Bt proteins, Bt corn and Bt cotton in a Cry2Ab2-corn resistant strain of Spodoptera frugiperda. Pest Manag Sci. 2017 Jun 19. PMID: 28627124.
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      3. Yang S, Wang Q, Fedorova E, Liu J, Qin Q, Zheng Q, Price P, Pan H, Wang D, Griffitts JS, Bisseling T, Zhu H. Microsymbiont discrimination mediated by a host-secreted peptide in Medicago truncatula. Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26):6848-6853. PMID: 28607056.
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      4. Moar W, Khajuria C, Pleau M, Ilagan O, Chen M, Jiang C, Price P, McNulty B, Clark T, Head G. Cry3Bb1-Resistant Western Corn Rootworm, Diabrotica virgifera virgifera (LeConte) Does Not Exhibit Cross-Resistance to DvSnf7 dsRNA. PLoS One. 2017; 12(1):e0169175. PMID: 28060922.
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      5. Nicholl M, Smartt SJ, Jerkstrand A, Inserra C, McCrum M, Kotak R, Fraser M, Wright D, Chen TW, Smith K, Young DR, Sim SA, Valenti S, Howell DA, Bresolin F, Kudritzki RP, Tonry JL, Huber ME, Rest A, Pastorello A, Tomasella L, Cappellaro E, Benetti S, Mattila S, Kankare E, Kangas T, Leloudas G, Sollerman J, Taddia F, Berger E, Chornock R, Narayan G, Stubbs CW, Foley RJ, Lunnan R, Soderberg A, Sanders N, Milisavljevic D, Margutti R, Kirshner RP, Elias-Rosa N, Morales-Garoffolo A, Taubenberger S, Botticella MT, Gezari S, Urata Y, Rodney S, Riess AG, Scolnic D, Wood-Vasey WM, Burgett WS, Chambers K, Flewelling HA, Magnier EA, Kaiser N, Metcalfe N, Morgan J, Price P, Sweeney W, Waters C. Corrigendum: Slowly fading super-luminous supernovae that are not pair-instability explosions. Nature. 2016 11 24; 539(7630):598. PMID: 27706143.
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      6. Shabab M, Arnold MF, Penterman J, Wommack AJ, Bocker HT, Price P, Griffitts JS, Nolan EM, Walker GC. Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247. Proc Natl Acad Sci U S A. 2016 Sep 06; 113(36):10157-62. PMID: 27551097; PMCID: PMC5018749 [Available on 03/06/17].
      7. Niu Y, Qureshi JA, Ni X, Head GP, Price P, Meagher RL, Kerns D, Levy R, Yang X, Huang F. F2 screen for resistance to Bacillus thuringiensis Cry2Ab2-maize in field populations of Spodoptera frugiperda (Lepidoptera: Noctuidae) from the southern United States. J Invertebr Pathol. 2016 Jul; 138:66-72. PMID: 27311896.
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      8. Stasulli NM, Eichelberger KR, Price P, Pechous RD, Montgomery SA, Parker JS, Goldman WE. Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague. MBio. 2015 Oct 13; 6(5):e01530-15. PMID: 26463167; PMCID: PMC4620470.
      9. Price P, Tanner HR, Dillon BA, Shabab M, Walker GC, Griffitts JS. Rhizobial peptidase HrrP cleaves host-encoded signaling peptides and mediates symbiotic compatibility. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):15244-9. PMID: 26401024; PMCID: PMC4679054.
      10. Lathem WW, Schroeder JA, Bellows LE, Ritzert JT, Koo JT, Price P, Caulfield AJ, Goldman WE. Posttranscriptional regulation of the Yersinia pestis cyclic AMP receptor protein Crp and impact on virulence. MBio. 2014 Feb 11; 5(1):e01038-13. PMID: 24520064; PMCID: PMC3950509.
      11. Cavaco S, Williamson MK, Rosa J, Roberto V, Cordeiro O, Price P, Leonor Cancela M, Laizé V, Simes DC. Teleost fish osteocalcin 1 and 2 share the ability to bind the calcium mineral phase. Fish Physiol Biochem. 2014 Jun; 40(3):731-8. PMID: 24185858.
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      12. Nicholl M, Smartt SJ, Jerkstrand A, Inserra C, McCrum M, Kotak R, Fraser M, Wright D, Chen TW, Smith K, Young DR, Sim SA, Valenti S, Howell DA, Bresolin F, Kudritzki RP, Tonry JL, Huber ME, Rest A, Pastorello A, Tomasella L, Cappellaro E, Benetti S, Mattila S, Kankare E, Kangas T, Leloudas G, Sollerman J, Taddia F, Berger E, Chornock R, Narayan G, Stubbs CW, Foley RJ, Lunnan R, Soderberg A, Sanders N, Milisavljevic D, Margutti R, Kirshner RP, Elias-Rosa N, Morales-Garoffolo A, Taubenberger S, Botticella MT, Gezari S, Urata Y, Rodney S, Riess AG, Scolnic D, Wood-Vasey WM, Burgett WS, Chambers K, Flewelling HA, Magnier EA, Kaiser N, Metcalfe N, Morgan J, Price P, Sweeney W, Waters C. Slowly fading super-luminous supernovae that are not pair-instability explosions. Nature. 2013 Oct 17; 502(7471):346-9. PMID: 24132291.
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      13. Pechous RD, Sivaraman V, Price P, Stasulli NM, Goldman WE. Early host cell targets of Yersinia pestis during primary pneumonic plague. PLoS Pathog. 2013; 9(10):e1003679. PMID: 24098126; PMCID: PMC3789773.
      14. Temple JH, Davis JA, Micinski S, Hardke JT, Price P, Leonard BR. Species composition and seasonal abundance of stink bugs (Hemiptera: Pentatomidae) in Louisiana soybean. Environ Entomol. 2013 Aug; 42(4):648-57. PMID: 23905727.
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      15. Viegas CS, Simes DC, Williamson MK, Cavaco S, Laizé V, Price P, Cancela ML. Sturgeon osteocalcin shares structural features with matrix Gla protein: evolutionary relationship and functional implications. J Biol Chem. 2013 Sep 27; 288(39):27801-11. PMID: 23884418; PMCID: PMC3784696.
      16. Gezari S, Chornock R, Rest A, Huber ME, Forster K, Berger E, Challis PJ, Neill JD, Martin DC, Heckman T, Lawrence A, Norman C, Narayan G, Foley RJ, Marion GH, Scolnic D, Chomiuk L, Soderberg A, Smith K, Kirshner RP, Riess AG, Smartt SJ, Stubbs CW, Tonry JL, Wood-Vasey WM, Burgett WS, Chambers KC, Grav T, Heasley JN, Kaiser N, Kudritzki RP, Magnier EA, Morgan JS, Price P. An ultraviolet-optical flare from the tidal disruption of a helium-rich stellar core. Nature. 2012 May 02; 485(7397):217-20. PMID: 22575962.
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      17. Price P, Jin J, Goldman WE. Pulmonary infection by Yersinia pestis rapidly establishes a permissive environment for microbial proliferation. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3083-8. PMID: 22308352; PMCID: PMC3286930.
      18. Chen PY, Toroian D, Price P, McKittrick J. Minerals form a continuum phase in mature cancellous bone. Calcif Tissue Int. 2011 May; 88(5):351-61. PMID: 21274705; PMCID: PMC3075393.
      19. Bobrov AG, Kirillina O, Ryjenkov DA, Waters CM, Price P, Fetherston JD, Mack D, Goldman WE, Gomelsky M, Perry RD. Systematic analysis of cyclic di-GMP signalling enzymes and their role in biofilm formation and virulence in Yersinia pestis. Mol Microbiol. 2011 Jan; 79(2):533-51. PMID: 21219468; PMCID: PMC3058942.
      20. Weening EH, Cathelyn JS, Kaufman G, Lawrenz MB, Price P, Goldman WE, Miller VL. The dependence of the Yersinia pestis capsule on pathogenesis is influenced by the mouse background. Infect Immun. 2011 Feb; 79(2):644-52. PMID: 21115720; PMCID: PMC3028848.
      21. Johansen JS, Bojesen SE, Tybjaerg-Hansen A, Mylin AK, Price P, Nordestgaard BG. Plasma YKL-40 and total and disease-specific mortality in the general population. Clin Chem. 2010 Oct; 56(10):1580-91. PMID: 20798353.
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      22. Viegas CS, Cavaco S, Neves PL, Ferreira A, João A, Williamson MK, Price P, Cancela ML, Simes DC. Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications. Am J Pathol. 2009 Dec; 175(6):2288-98. PMID: 19893032; PMCID: PMC2789615.
      23. Price P, Toroian D, Lim JE. Mineralization by inhibitor exclusion: the calcification of collagen with fetuin. J Biol Chem. 2009 Jun 19; 284(25):17092-101. PMID: 19414589; PMCID: PMC2719347.
      24. Shea MK, O'Donnell CJ, Hoffmann U, Dallal GE, Dawson-Hughes B, Ordovas JM, Price P, Williamson MK, Booth SL. Vitamin K supplementation and progression of coronary artery calcium in older men and women. Am J Clin Nutr. 2009 Jun; 89(6):1799-807. PMID: 19386744; PMCID: PMC2682995.
      25. Ix JH, Wassel CL, Bauer DC, Toroian D, Tylavsky FA, Cauley JA, Harris TB, Price P, Cummings SR, Shlipak MG. Fetuin-A and BMD in older persons: the Health Aging and Body Composition (Health ABC) study. J Bone Miner Res. 2009 Mar; 24(3):514-21. PMID: 19016589; PMCID: PMC2659522.
      26. Crosier MD, Booth SL, Peter I, Dawson-Hughes B, Price P, O'Donnell CJ, Hoffmann U, Williamson MK, Ordovas JM. Matrix Gla protein polymorphisms are associated with coronary artery calcification in men. J Nutr Sci Vitaminol (Tokyo). 2009 Feb; 55(1):59-65. PMID: 19352064; PMCID: PMC2706526.
      27. Høgdall EV, Ringsholt M, Høgdall CK, Christensen IJ, Johansen JS, Kjaer SK, Blaakaer J, Ostenfeld-Møller L, Price P, Christensen LH. YKL-40 tissue expression and plasma levels in patients with ovarian cancer. BMC Cancer. 2009 Jan 09; 9:8. PMID: 19134206; PMCID: PMC2645422.
      28. Price P, Toroian D, Chan WS. Tissue-nonspecific alkaline phosphatase is required for the calcification of collagen in serum: a possible mechanism for biomineralization. J Biol Chem. 2009 Feb 13; 284(7):4594-604. PMID: 19098289.
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      29. Johansen JS, Bojesen SE, Mylin AK, Frikke-Schmidt R, Price P, Nordestgaard BG. Elevated plasma YKL-40 predicts increased risk of gastrointestinal cancer and decreased survival after any cancer diagnosis in the general population. J Clin Oncol. 2009 Feb 01; 27(4):572-8. PMID: 19075264.
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      30. Viegas CS, Simes DC, Laizé V, Williamson MK, Price P, Cancela ML. Gla-rich protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates. J Biol Chem. 2008 Dec 26; 283(52):36655-64. PMID: 18836183; PMCID: PMC2605998.
      31. Nøjgaard C, Høst NB, Christensen IJ, Poulsen SH, Egstrup K, Price P, Johansen JS. Serum levels of YKL-40 increases in patients with acute myocardial infarction. Coron Artery Dis. 2008 Jun; 19(4):257-63. PMID: 18480670.
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      32. Roslind A, Johansen JS, Christensen IJ, Kiss K, Balslev E, Nielsen DL, Bentzen J, Price P, Andersen E. High serum levels of YKL-40 in patients with squamous cell carcinoma of the head and neck are associated with short survival. Int J Cancer. 2008 Feb 15; 122(4):857-63. PMID: 17957792.
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      33. Roslind A, Knoop AS, Jensen MB, Johansen JS, Nielsen DL, Price P, Balslev E. YKL-40 protein expression is not a prognostic marker in patients with primary breast cancer. Breast Cancer Res Treat. 2008 Nov; 112(2):275-85. PMID: 18157633.
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      34. Toroian D, Price P. The essential role of fetuin in the serum-induced calcification of collagen. Calcif Tissue Int. 2008 Feb; 82(2):116-26. PMID: 18097630.
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      35. Roslind A, Johansen JS, Junker N, Nielsen DL, Dzaferi H, Price P, Balslev E. YKL-40 expression in benign and malignant lesions of the breast: a methodologic study. Appl Immunohistochem Mol Morphol. 2007 Dec; 15(4):371-81. PMID: 18091378.
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      36. Silva P, Homer JJ, Slevin NJ, Musgrove BT, Sloan P, Price P, West CM. Clinical and biological factors affecting response to radiotherapy in patients with head and neck cancer: a review. Clin Otolaryngol. 2007 Oct; 32(5):337-45. PMID: 17883552.
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      37. Johansen JS, Høyer PE, Larsen LA, Price P, Møllgård K. YKL-40 protein expression in the early developing human musculoskeletal system. J Histochem Cytochem. 2007 Dec; 55(12):1213-28. PMID: 17712177.
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      38. Toroian D, Lim JE, Price P. The size exclusion characteristics of type I collagen: implications for the role of noncollagenous bone constituents in mineralization. J Biol Chem. 2007 Aug 03; 282(31):22437-47. PMID: 17562713.
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      39. Johansen JS, Brasso K, Iversen P, Teisner B, Garnero P, Price P, Christensen IJ. Changes of biochemical markers of bone turnover and YKL-40 following hormonal treatment for metastatic prostate cancer are related to survival. Clin Cancer Res. 2007 Jun 01; 13(11):3244-9. PMID: 17545529.
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      40. Johansen JS, Jensen BV, Roslind A, Price P. Is YKL-40 a new therapeutic target in cancer? Expert Opin Ther Targets. 2007 Feb; 11(2):219-34. PMID: 17227236.
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      41. Lathem WW, Price P, Miller VL, Goldman WE. A plasminogen-activating protease specifically controls the development of primary pneumonic plague. Science. 2007 Jan 26; 315(5811):509-13. PMID: 17255510.
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      42. Ringsholt M, Høgdall EV, Johansen JS, Price P, Christensen LH. YKL-40 protein expression in normal adult human tissues--an immunohistochemical study. J Mol Histol. 2007 Mar; 38(1):33-43. PMID: 17242979.
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      43. Gal-Yam A, Fox DB, Price P, Ofek EO, Davis MR, Leonard DC, Soderberg AM, Schmidt BP, Lewis KM, Peterson BA, Kulkarni SR, Berger E, Cenko SB, Sari R, Sharon K, Frail D, Moon DS, Brown PJ, Cucchiara A, Harrison F, Piran T, Persson SE, McCarthy PJ, Penprase BE, Chevalier RA, MacFadyen AI. A novel explosive process is required for the gamma-ray burst GRB 060614. Nature. 2006 Dec 21; 444(7122):1053-5. PMID: 17183318.
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      44. O'Donnell CJ, Shea MK, Price P, Gagnon DR, Wilson PW, Larson MG, Kiel DP, Hoffmann U, Ferencik M, Clouse ME, Williamson MK, Cupples LA, Dawson-Hughes B, Booth SL. Matrix Gla protein is associated with risk factors for atherosclerosis but not with coronary artery calcification. Arterioscler Thromb Vasc Biol. 2006 Dec; 26(12):2769-74. PMID: 16973975; PMCID: PMC2562549.
      45. Price P, Roublick AM, Williamson MK. Artery calcification in uremic rats is increased by a low protein diet and prevented by treatment with ibandronate. Kidney Int. 2006 Nov; 70(9):1577-83. PMID: 16955099.
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      46. Hamlin NJ, Ong KG, Price P. A serum factor that recalcifies demineralized bone is conserved in bony fish and sharks but is not found in invertebrates. Calcif Tissue Int. 2006 May; 78(5):326-34. PMID: 16691496.
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      47. Brasso K, Christensen IJ, Johansen JS, Teisner B, Garnero P, Price P, Iversen P. Prognostic value of PINP, bone alkaline phosphatase, CTX-I, and YKL-40 in patients with metastatic prostate carcinoma. Prostate. 2006 Apr 01; 66(5):503-13. PMID: 16372331.
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      48. Laizé V, Viegas CS, Price P, Cancela ML. Identification of an osteocalcin isoform in fish with a large acidic prodomain. J Biol Chem. 2006 Jun 02; 281(22):15037-43. PMID: 16565091.
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      49. Haislip JB, Nysewander MC, Reichart DE, Levan A, Tanvir N, Cenko SB, Fox DB, Price P, Castro-Tirado AJ, Gorosabel J, Evans CR, Figueredo E, MacLeod CL, Kirschbrown JR, Jelinek M, Guziy S, de Ugarte Postigo A, Cypriano ES, LaCluyze A, Graham J, Priddey R, Chapman R, Rhoads J, Fruchter AS, Lamb DQ, Kouveliotou C, Wijers RA, Bayliss MB, Schmidt BP, Soderberg AM, Kulkarni SR, Harrison FA, Moon DS, Gal-Yam A, Kasliwal MM, Hudec R, Vitek S, Kubanek P, Crain JA, Foster AC, Clemens JC, Bartelme JW, Canterna R, Hartmann DH, Henden AA, Klose S, Park HS, Williams GG, Rol E, O'Brien P, Bersier D, Prada F, Pizarro S, Maturana D, Ugarte P, Alvarez A, Fernandez AJ, Jarvis MJ, Moles M, Alfaro E, Ivarsen KM, Kumar ND, Mack CE, Zdarowicz CM, Gehrels N, Barthelmy S, Burrows DN. A photometric redshift of z = 6.39 +/- 0.12 for GRB 050904. Nature. 2006 Mar 09; 440(7081):181-3. PMID: 16525465.
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      50. Price P, Chan WS, Jolson DM, Williamson MK. The elastic lamellae of devitalized arteries calcify when incubated in serum: evidence for a serum calcification factor. Arterioscler Thromb Vasc Biol. 2006 May; 26(5):1079-85. PMID: 16528009.
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      51. Johansen JS, Jensen BV, Roslind A, Nielsen D, Price P. Serum YKL-40, a new prognostic biomarker in cancer patients? Cancer Epidemiol Biomarkers Prev. 2006 Feb; 15(2):194-202. PMID: 16492905.
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      52. Berger E, Price P, Cenko SB, Gal-Yam A, Soderberg AM, Kasliwal M, Leonard DC, Cameron PB, Frail DA, Kulkarni SR, Murphy DC, Krzeminski W, Piran T, Lee BL, Roth KC, Moon DS, Fox DB, Harrison FA, Persson SE, Schmidt BP, Penprase BE, Rich J, Peterson BA, Cowie LL. The afterglow and elliptical host galaxy of the short gamma-ray burst GRB 050724. Nature. 2005 Dec 15; 438(7070):988-90. PMID: 16355217.
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      53. Hjorth J, Watson D, Fynbo JP, Price P, Jensen BL, Jørgensen UG, Kubas D, Gorosabel J, Jakobsson P, Sollerman J, Pedersen K, Kouveliotou C. The optical afterglow of the short gamma-ray burst GRB 050709. Nature. 2005 Oct 06; 437(7060):859-61. PMID: 16208365.
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      54. Fox DB, Frail DA, Price P, Kulkarni SR, Berger E, Piran T, Soderberg AM, Cenko SB, Cameron PB, Gal-Yam A, Kasliwal MM, Moon DS, Harrison FA, Nakar E, Schmidt BP, Penprase B, Chevalier RA, Kumar P, Roth K, Watson D, Lee BL, Shectman S, Phillips MM, Roth M, McCarthy PJ, Rauch M, Cowie L, Peterson BA, Rich J, Kawai N, Aoki K, Kosugi G, Totani T, Park HS, MacFadyen A, Hurley KC. The afterglow of GRB 050709 and the nature of the short-hard gamma-ray bursts. Nature. 2005 Oct 06; 437(7060):845-50. PMID: 16208362.
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      55. Nordenbaek C, Johansen JS, Halberg P, Wiik A, Garbarsch C, Ullman S, Price P, Jacobsen S. High serum levels of YKL-40 in patients with systemic sclerosis are associated with pulmonary involvement. Scand J Rheumatol. 2005 Jul-Aug; 34(4):293-7. PMID: 16195162.
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      56. Laizé V, Martel P, Viegas CS, Price P, Cancela ML. Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates. J Biol Chem. 2005 Jul 22; 280(29):26659-68. PMID: 15849363.
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      57. Frazão C, Simes DC, Coelho R, Alves D, Williamson MK, Price P, Cancela ML, Carrondo MA. Structural evidence of a fourth Gla residue in fish osteocalcin: biological implications. Biochemistry. 2005 Feb 01; 44(4):1234-42. PMID: 15667217.
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      58. Johansen JS, Drivsholm L, Price P, Christensen IJ. High serum YKL-40 level in patients with small cell lung cancer is related to early death. Lung Cancer. 2004 Dec; 46(3):333-40. PMID: 15541818.
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      59. Johansen JS, Milman N, Hansen M, Garbarsch C, Price P, Graudal N. Increased serum YKL-40 in patients with pulmonary sarcoidosis--a potential marker of disease activity? Respir Med. 2005 Apr; 99(4):396-402. PMID: 15763444.
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      60. Hamlin NJ, Price P. Mineralization of decalcified bone occurs under cell culture conditions and requires bovine serum but not cells. Calcif Tissue Int. 2004 Sep; 75(3):231-42. PMID: 15164149.
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      61. Gravekamp C, Sypniewska R, Gauntt S, Tarango M, Price P, Reddick R. Behavior of metastatic and nonmetastatic breast tumors in old mice. Exp Biol Med (Maywood). 2004 Jul; 229(7):665-75. PMID: 15229361.
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      62. Price P, June HH, Hamlin NJ, Williamson MK. Evidence for a serum factor that initiates the re-calcification of demineralized bone. J Biol Chem. 2004 Apr 30; 279(18):19169-80. PMID: 14978037.
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      63. Simes DC, Williamson MK, Schaff BJ, Gavaia PJ, Ingleton PM, Price P, Cancela ML. Characterization of osteocalcin (BGP) and matrix Gla protein (MGP) fish specific antibodies: validation for immunodetection studies in lower vertebrates. Calcif Tissue Int. 2004 Feb; 74(2):170-80. PMID: 14668966.
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      64. Price P, Williamson MK, Nguyen TM, Than TN. Serum levels of the fetuin-mineral complex correlate with artery calcification in the rat. J Biol Chem. 2004 Jan 16; 279(3):1594-600. PMID: 14578360.
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      65. Jensen BV, Johansen JS, Price P. High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer. Clin Cancer Res. 2003 Oct 01; 9(12):4423-34. PMID: 14555515.
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      66. Høgdall EV, Johansen JS, Kjaer SK, Price P, Christensen L, Blaakaer J, Bock JE, Glud E, Høgdall CK. High plasma YKL-40 level in patients with ovarian cancer stage III is related to shorter survival. Oncol Rep. 2003 Sep-Oct; 10(5):1535-8. PMID: 12883737.
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      67. Nøjgaard C, Johansen JS, Christensen E, Skovgaard LT, Price P, Becker U. Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease. J Hepatol. 2003 Aug; 39(2):179-86. PMID: 12873813.
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      68. Anderson H, Yap JT, Wells P, Miller MP, Propper D, Price P, Harris AL. Measurement of renal tumour and normal tissue perfusion using positron emission tomography in a phase II clinical trial of razoxane. Br J Cancer. 2003 Jul 21; 89(2):262-7. PMID: 12865914; PMCID: PMC2394254.
      69. Johansen JS, Christensen IJ, Riisbro R, Greenall M, Han C, Price P, Smith K, Brünner N, Harris AL. High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival. Breast Cancer Res Treat. 2003 Jul; 80(1):15-21. PMID: 12889595.
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      70. Price P, Fox DW, Kulkarni SR, Peterson BA, Schmidt BP, Soderberg AM, Yost SA, Berger E, Djorgovski SG, Frail DA, Harrison FA, Sari R, Blain AW, Chapman SC. The bright optical afterglow of the nearby gamma-ray burst of 29 March 2003. Nature. 2003 Jun 19; 423(6942):844-7. PMID: 12815424.
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      71. Vind I, Johansen JS, Price P, Munkholm P. Serum YKL-40, a potential new marker of disease activity in patients with inflammatory bowel disease. Scand J Gastroenterol. 2003 Jun; 38(6):599-605. PMID: 12825867.
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      72. Price P, Lim JE. The inhibition of calcium phosphate precipitation by fetuin is accompanied by the formation of a fetuin-mineral complex. J Biol Chem. 2003 Jun 13; 278(24):22144-52. PMID: 12676929.
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      73. Price P, Nguyen TM, Williamson MK. Biochemical characterization of the serum fetuin-mineral complex. J Biol Chem. 2003 Jun 13; 278(24):22153-60. PMID: 12676928.
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      74. Fox DW, Yost S, Kulkarni SR, Torii K, Kato T, Yamaoka H, Sako M, Harrison FA, Sari R, Price P, Berger E, Soderberg AM, Djorgovski SG, Barth AJ, Pravdo SH, Frail DA, Gal-Yam A, Lipkin Y, Mauch T, Harrison C, Buttery H. Early optical emission from the gamma-ray burst of 4 October 2002. Nature. 2003 Mar 20; 422(6929):284-6. PMID: 12646914.
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      75. Dehn H, Høgdall EV, Johansen JS, Jørgensen M, Price P, Engelholm SA, Høgdall CK. Plasma YKL-40, as a prognostic tumor marker in recurrent ovarian cancer. Acta Obstet Gynecol Scand. 2003 Mar; 82(3):287-93. PMID: 12694127.
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      76. Simes DC, Williamson MK, Ortiz-Delgado JB, Viegas CS, Price P, Cancela ML. Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish. J Bone Miner Res. 2003 Feb; 18(2):244-59. PMID: 12568402.
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      77. Propper DJ, de Bono J, Saleem A, Ellard S, Flanagan E, Paul J, Ganesan TS, Talbot DC, Aboagye EO, Price P, Harris AL, Twelves C. Use of positron emission tomography in pharmacokinetic studies to investigate therapeutic advantage in a phase I study of 120-hour intravenous infusion XR5000. J Clin Oncol. 2003 Jan 15; 21(2):203-10. PMID: 12525511.
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      78. Liu D, Xu JK, Figliomeni L, Huang L, Pavlos NJ, Rogers M, Tan A, Price P, Zheng MH. Expression of RANKL and OPG mRNA in periodontal disease: possible involvement in bone destruction. Int J Mol Med. 2003 Jan; 11(1):17-21. PMID: 12469211.
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      79. Price P, June HH, Buckley JR, Williamson MK. SB 242784, a selective inhibitor of the osteoclastic V-H+ATPase, inhibits arterial calcification in the rat. Circ Res. 2002 Sep 20; 91(6):547-52. PMID: 12242274.
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      80. Price P, Omid N, Than TN, Williamson MK. The amino bisphosphonate ibandronate prevents calciphylaxis in the rat at doses that inhibit bone resorption. Calcif Tissue Int. 2002 Oct; 71(4):356-63. PMID: 12183764.
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      81. Cintin C, Johansen JS, Christensen IJ, Price P, Sørensen S, Nielsen HJ. High serum YKL-40 level after surgery for colorectal carcinoma is related to short survival. Cancer. 2002 Jul 15; 95(2):267-74. PMID: 12124825.
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      82. Price P, Caputo JM, Williamson MK. Bone origin of the serum complex of calcium, phosphate, fetuin, and matrix Gla protein: biochemical evidence for the cancellous bone-remodeling compartment. J Bone Miner Res. 2002 Jul; 17(7):1171-9. PMID: 12096831.
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      83. Østergaard C, Johansen JS, Benfield T, Price P, Lundgren JD. YKL-40 is elevated in cerebrospinal fluid from patients with purulent meningitis. Clin Diagn Lab Immunol. 2002 May; 9(3):598-604. PMID: 11986266; PMCID: PMC119997.
      84. Brünner N, Double J, Fichtner I, Gescher A, Newell D, Oosterhuis W, Price P. The EORTC Laboratory Research Division. European Organisation for Research and Treatment of Cancer. Eur J Cancer. 2002 Mar; 38 Suppl 4:S14-8. PMID: 11858958.
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      85. Kronborg G, Ostergaard C, Weis N, Nielsen H, Obel N, Pedersen SS, Price P, Johansen JS. Serum level of YKL-40 is elevated in patients with Streptococcus pneumoniae bacteremia and is associated with the outcome of the disease. Scand J Infect Dis. 2002; 34(5):323-6. PMID: 12069012.
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      86. Price P, Thomas GR, Pardini AW, Figueira WF, Caputo JM, Williamson MK. Discovery of a high molecular weight complex of calcium, phosphate, fetuin, and matrix gamma-carboxyglutamic acid protein in the serum of etidronate-treated rats. J Biol Chem. 2002 Feb 08; 277(6):3926-34. PMID: 11724771.
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      87. Price P, Buckley JR, Williamson MK. The amino bisphosphonate ibandronate prevents vitamin D toxicity and inhibits vitamin D-induced calcification of arteries, cartilage, lungs and kidneys in rats. J Nutr. 2001 Nov; 131(11):2910-5. PMID: 11694617.
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      88. Price P, June HH, Buckley JR, Williamson MK. Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D. Arterioscler Thromb Vasc Biol. 2001 Oct; 21(10):1610-6. PMID: 11597934.
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      89. Keane NM, Price P, Lee S, Stone SF, French MA. An evaluation of serum soluble CD30 levels and serum CD26 (DPPIV) enzyme activity as markers of type 2 and type 1 cytokines in HIV patients receiving highly active antiretroviral therapy. Clin Exp Immunol. 2001 Oct; 126(1):111-6. PMID: 11678906; PMCID: PMC1906164.
      90. Cancela ML, Ohresser MC, Reia JP, Viegas CS, Williamson MK, Price P. Matrix Gla protein in Xenopus laevis: molecular cloning, tissue distribution, and evolutionary considerations. J Bone Miner Res. 2001 Sep; 16(9):1611-21. PMID: 11550673.
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      91. Price P, Faus SA, Williamson MK. Bisphosphonates alendronate and ibandronate inhibit artery calcification at doses comparable to those that inhibit bone resorption. Arterioscler Thromb Vasc Biol. 2001 May; 21(5):817-24. PMID: 11348880.
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      92. Johansen JS, Olee T, Price P, Hashimoto S, Ochs RL, Lotz M. Regulation of YKL-40 production by human articular chondrocytes. Arthritis Rheum. 2001 Apr; 44(4):826-37. PMID: 11315922.
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      93. Volck B, Johansen JS, Stoltenberg M, Garbarsch C, Price P, Ostergaard M, Ostergaard K, Løvgreen-Nielsen P, Sonne-Holm S, Lorenzen I. Studies on YKL-40 in knee joints of patients with rheumatoid arthritis and osteoarthritis. Involvement of YKL-40 in the joint pathology. Osteoarthritis Cartilage. 2001 Apr; 9(3):203-14. PMID: 11300743.
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      94. Cintin C, Johansen JS, Skov F, Price P, Nielsen HJ. Accumulation of the neutrophil-derived protein YKL-40 during storage of various blood components. Inflamm Res. 2001 Feb; 50(2):107-11. PMID: 11289654.
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      95. Johansen JS, Kirwan JR, Price P, Sharif M. Serum YKL-40 concentrations in patients with early rheumatoid arthritis: relation to joint destruction. Scand J Rheumatol. 2001; 30(5):297-304. PMID: 11727845.
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      96. Matthews VB, Price P. The H2(b) haplotype modifies the production of pro-inflammatory cytokines: implications for immunopathology. Eur Cytokine Netw. 2000 Dec; 11(4):640-6. PMID: 11125308.
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      97. Knapen MH, Hellemons-Boode BS, Langenberg-Ledeboer M, Knottnerus JA, Hamulyák K, Price P, Vermeer C. Effect of oral anticoagulant treatment on markers for calcium and bone metabolism. Haemostasis. 2000 Nov-Dec; 30(6):290-7. PMID: 11356997.
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      98. Høgdall EV, Johansen JS, Kjaer SK, Price P, Blaakjaer J, Høgdall CK. Stability of YKL-40 concentration in blood samples. Scand J Clin Lab Invest. 2000 Jul; 60(4):247-51. PMID: 10943594.
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      99. Johansen JS, Christoffersen P, Møller S, Price P, Henriksen JH, Garbarsch C, Bendtsen F. Serum YKL-40 is increased in patients with hepatic fibrosis. J Hepatol. 2000 Jun; 32(6):911-20. PMID: 10898311.
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      100. Price P, Faus SA, Williamson MK. Warfarin-induced artery calcification is accelerated by growth and vitamin D. Arterioscler Thromb Vasc Biol. 2000 Feb; 20(2):317-27. PMID: 10669626.
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      101. Johansen JS, Baslund B, Garbarsch C, Hansen M, Stoltenberg M, Lorenzen I, Price P. YKL-40 in giant cells and macrophages from patients with giant cell arteritis. Arthritis Rheum. 1999 Dec; 42(12):2624-30. PMID: 10616010.
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      102. Nordenbaek C, Johansen JS, Junker P, Borregaard N, Sørensen O, Price P. YKL-40, a matrix protein of specific granules in neutrophils, is elevated in serum of patients with community-acquired pneumonia requiring hospitalization. J Infect Dis. 1999 Nov; 180(5):1722-6. PMID: 10515841.
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      103. Johansen JS, Stoltenberg M, Hansen M, Florescu A, Hørslev-Petersen K, Lorenzen I, Price P. Serum YKL-40 concentrations in patients with rheumatoid arthritis: relation to disease activity. Rheumatology (Oxford). 1999 Jul; 38(7):618-26. PMID: 10461474.
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      104. Cintin C, Johansen JS, Christensen IJ, Price P, Sørensen S, Nielsen HJ. Serum YKL-40 and colorectal cancer. Br J Cancer. 1999 Mar; 79(9-10):1494-9. PMID: 10188896; PMCID: PMC2362720.
      105. Volck B, Ostergaard K, Johansen JS, Garbarsch C, Price P. The distribution of YKL-40 in osteoarthritic and normal human articular cartilage. Scand J Rheumatol. 1999; 28(3):171-9. PMID: 10380840.
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      106. Herbison CE, Sayer DC, Bellgard M, Allcock RJ, Christiansen FT, Price P. Structure and polymorphism of two stress-activated protein kinase genes centromeric of the MHC: SAPK2a and SAPK4. DNA Seq. 1999; 10(4-5):229-43. PMID: 10727080.
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      107. Allcock RJ, Price P, Gaudieri S, Leelayuwat C, Witt CS, Dawkins RL. Characterisation of the human central MHC gene, BAT1: genomic structure and expression. Exp Clin Immunogenet. 1999; 16(2):98-106. PMID: 10343160.
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      108. Price P, Faus SA, Williamson MK. Warfarin causes rapid calcification of the elastic lamellae in rat arteries and heart valves. Arterioscler Thromb Vasc Biol. 1998 Sep; 18(9):1400-7. PMID: 9743228.
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      109. Volck B, Price P, Johansen JS, Sørensen O, Benfield TL, Nielsen HJ, Calafat J, Borregaard N. YKL-40, a mammalian member of the chitinase family, is a matrix protein of specific granules in human neutrophils. Proc Assoc Am Physicians. 1998 Jul-Aug; 110(4):351-60. PMID: 9686683.
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      110. Bronckers AL, Price P, Schrijvers A, Bervoets TJ, Karsenty G. Studies of osteocalcin function in dentin formation in rodent teeth. Eur J Oral Sci. 1998 Jun; 106(3):795-807. PMID: 9672102.
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      111. Johansen JS, Møller S, Price P, Bendtsen F, Junge J, Garbarsch C, Henriksen JH. Plasma YKL-40: a new potential marker of fibrosis in patients with alcoholic cirrhosis? Scand J Gastroenterol. 1997 Jun; 32(6):582-90. PMID: 9200292.
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      112. Cancela ML, Hu B, Price P. Effect of cell density and growth factors on matrix GLA protein expression by normal rat kidney cells. J Cell Physiol. 1997 May; 171(2):125-34. PMID: 9130459.
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      113. Kirfel J, Kelter M, Cancela LM, Price P, Schüle R. Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2227-32. PMID: 9122176; PMCID: PMC20069.
      114. Baumgrass R, Williamson MK, Price P. Identification of peptide fragments generated by digestion of bovine and human osteocalcin with the lysosomal proteinases cathepsin B, D, L, H, and S. J Bone Miner Res. 1997 Mar; 12(3):447-55. PMID: 9076588.
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      115. Hu B, Trinh K, Figueira WF, Price P. Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family. J Biol Chem. 1996 Aug 09; 271(32):19415-20. PMID: 8702629.
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      116. Johansen JS, Hvolris J, Hansen M, Backer V, Lorenzen I, Price P. Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee joint. Br J Rheumatol. 1996 Jun; 35(6):553-9. PMID: 8670576.
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      117. Cancela ML, Williamson MK, Price P. Amino-acid sequence of bone Gla protein from the African clawed toad Xenopus laevis and the fish Sparus aurata. Int J Pept Protein Res. 1995 Nov; 46(5):419-23. PMID: 8567186.
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      118. Serre CM, Price P, Delmas PD. Degradation of subcutaneous implants of bone particles from normal and warfarin-treated rats. J Bone Miner Res. 1995 Aug; 10(8):1158-67. PMID: 8585418.
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      119. Benton ME, Price P, Suttie JW. Multi-site-specificity of the vitamin K-dependent carboxylase: in vitro carboxylation of des-gamma-carboxylated bone Gla protein and Des-gamma-carboxylated pro bone Gla protein. Biochemistry. 1995 Jul 25; 34(29):9541-51. PMID: 7626624.
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      120. Thomas H, Nasim MM, Sarraf CE, Alison MR, Love S, Lambert HE, Price P. Proliferating cell nuclear antigen (PCNA) immunostaining--a prognostic factor in ovarian cancer? Br J Cancer. 1995 Feb; 71(2):357-62. PMID: 7841053; PMCID: PMC2033602.
      121. Hu B, Coulson L, Moyer B, Price P. Isolation and molecular cloning of a novel bone phosphoprotein related in sequence to the cystatin family of thiol protease inhibitors. J Biol Chem. 1995 Jan 06; 270(1):431-6. PMID: 7814406.
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      122. Johansen JS, Cintin C, Jørgensen M, Kamby C, Price P. Serum YKL-40: a new potential marker of prognosis and location of metastases of patients with recurrent breast cancer. Eur J Cancer. 1995; 31A(9):1437-42. PMID: 7577068.
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      123. Cairns JR, Price P. Direct demonstration that the vitamin K-dependent bone Gla protein is incompletely gamma-carboxylated in humans. J Bone Miner Res. 1994 Dec; 9(12):1989-97. PMID: 7872066.
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      124. Price P, Rice JS, Williamson MK. Conserved phosphorylation of serines in the Ser-X-Glu/Ser(P) sequences of the vitamin K-dependent matrix Gla protein from shark, lamb, rat, cow, and human. Protein Sci. 1994 May; 3(5):822-30. PMID: 8061611; PMCID: PMC2142713.
      125. Cancela ML, Williamson MK, Price P. The putative RGD-dependent cell adhesion activity of matrix Gla protein is due to higher molecular weight contaminants. J Biol Chem. 1994 Apr 22; 269(16):12185-9. PMID: 8163523.
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      126. Rice JS, Williamson MK, Price P. Isolation and sequence of the vitamin K-dependent matrix Gla protein from the calcified cartilage of the soupfin shark. J Bone Miner Res. 1994 Apr; 9(4):567-76. PMID: 8030445.
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      127. Price P, Williamson MK. Substrate recognition by the vitamin K-dependent gamma-glutamyl carboxylase: identification of a sequence homology between the carboxylase and the carboxylase recognition site in the substrate. Protein Sci. 1993 Nov; 2(11):1987-8. PMID: 8268808; PMCID: PMC2142282.
      128. Johansen JS, Jensen HS, Price P. A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid. Br J Rheumatol. 1993 Nov; 32(11):949-55. PMID: 8220933.
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      129. Rannels SR, Cancela ML, Wolpert EB, Price P. Matrix Gla protein mRNA expression in cultured type II pneumocytes. Am J Physiol. 1993 Sep; 265(3 Pt 1):L270-8. PMID: 8214087.
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      130. Fournier B, Ferralli JM, Price P, Schlaeppi JM. Comparison of the effects of insulin-like growth factors-I and -II on the human osteosarcoma cell line OHS-4. J Endocrinol. 1993 Jan; 136(1):173-80. PMID: 8429272.
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      131. Johansen JS, Williamson MK, Rice JS, Price P. Identification of proteins secreted by human osteoblastic cells in culture. J Bone Miner Res. 1992 May; 7(5):501-12. PMID: 1615759.
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      132. Michaelsen KF, Johansen JS, Samuelson G, Price P, Christiansen C. Serum bone gamma-carboxyglutamic acid protein in a longitudinal study of infants: lower values in formula-fed infants. Pediatr Res. 1992 Apr; 31(4 Pt 1):401-5. PMID: 1570207.
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      133. Cancela ML, Price P. Retinoic acid induces matrix Gla protein gene expression in human cells. Endocrinology. 1992 Jan; 130(1):102-8. PMID: 1727694.
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      134. Bick DP, Schorderet DF, Price P, Campbell L, Huff RW, Shapiro LJ, Moore CM. Prenatal diagnosis and investigation of a fetus with chondrodysplasia punctata, ichthyosis, and Kallmann syndrome due to an Xp deletion. Prenat Diagn. 1992 Jan; 12(1):19-29. PMID: 1557308.
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      135. Cairns JR, Williamson MK, Price P. Direct identification of gamma-carboxyglutamic acid in the sequencing of vitamin K-dependent proteins. Anal Biochem. 1991 Nov 15; 199(1):93-7. PMID: 1807167.
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      136. Hale JE, Williamson MK, Price P. Carboxyl-terminal proteolytic processing of matrix Gla protein. J Biol Chem. 1991 Nov 05; 266(31):21145-9. PMID: 1939157.
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      137. Gorter de Vries I, Wisse E, Williamson MK, Price P. Effect of warfarin on early rat tooth development. Calcif Tissue Int. 1991 Nov; 49(5):355-8. PMID: 1782575.
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      138. Fournier B, Price P. Characterization of a new human osteosarcoma cell line OHS-4. J Cell Biol. 1991 Aug; 114(3):577-83. PMID: 1860886; PMCID: PMC2289099.
      139. Engelke JA, Hale JE, Suttie JW, Price P. Vitamin K-dependent carboxylase: utilization of decarboxylated bone Gla protein and matrix Gla protein as substrates. Biochim Biophys Acta. 1991 May 30; 1078(1):31-4. PMID: 2049381.
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      140. Cancela L, Hsieh CL, Francke U, Price P. Molecular structure, chromosome assignment, and promoter organization of the human matrix Gla protein gene. J Biol Chem. 1990 Sep 05; 265(25):15040-8. PMID: 2394711.
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      141. Fraser JD, Price P. Induction of matrix Gla protein synthesis during prolonged 1,25-dihydroxyvitamin D3 treatment of osteosarcoma cells. Calcif Tissue Int. 1990 Apr; 46(4):270-9. PMID: 2108798.
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      142. Delmas PD, Price P, Mann KG. Validation of the bone Gla protein (osteocalcin) assay. J Bone Miner Res. 1990 Jan; 5(1):3-4. PMID: 2309576.
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      143. Delmas PD, Christiansen C, Mann KG, Price P. Bone Gla protein (osteocalcin) assay standardization report. J Bone Miner Res. 1990 Jan; 5(1):5-11. PMID: 2309579.
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      144. Theofan G, Haberstroh LM, Price P. Molecular structure of the rat bone Gla protein gene and identification of putative regulatory elements. DNA. 1989 Apr; 8(3):213-21. PMID: 2785907.
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      145. Theofan G, Price P. Bone Gla protein messenger ribonucleic acid is regulated by both 1,25-dihydroxyvitamin D3 and 3',5'-cyclic adenosine monophosphate in rat osteosarcoma cells. Mol Endocrinol. 1989 Jan; 3(1):36-43. PMID: 2464756.
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      146. Price P. Gla-containing proteins of bone. Connect Tissue Res. 1989; 21(1-4):51-7; discussion 57-60. PMID: 2691199.
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      147. Gusterson BA, Machin LG, Gullick WJ, Gibbs NM, Powles TJ, Price P, McKinna A, Harrison S. Immunohistochemical distribution of c-erbB-2 in infiltrating and in situ breast cancer. Int J Cancer. 1988 Dec 15; 42(6):842-5. PMID: 2903851.
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      148. Fraser JD, Price P. Lung, heart, and kidney express high levels of mRNA for the vitamin K-dependent matrix Gla protein. Implications for the possible functions of matrix Gla protein and for the tissue distribution of the gamma-carboxylase. J Biol Chem. 1988 Aug 15; 263(23):11033-6. PMID: 3042764.
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      149. Johansen JS, Giwercman A, Hartwell D, Nielsen CT, Price P, Christiansen C, Skakkebaek NE. Serum bone Gla-protein as a marker of bone growth in children and adolescents: correlation with age, height, serum insulin-like growth factor I, and serum testosterone. J Clin Endocrinol Metab. 1988 Aug; 67(2):273-8. PMID: 3260598.
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      150. Hale JE, Fraser JD, Price P. The identification of matrix Gla protein in cartilage. J Biol Chem. 1988 Apr 25; 263(12):5820-4. PMID: 3258600.
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      151. Fraser JD, Otawara Y, Price P. 1,25-Dihydroxyvitamin D3 stimulates the synthesis of matrix gamma-carboxyglutamic acid protein by osteosarcoma cells. Mutually exclusive expression of vitamin K-dependent bone proteins by clonal osteoblastic cell lines. J Biol Chem. 1988 Jan 15; 263(2):911-6. PMID: 3257212.
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      152. Price P. Role of vitamin-K-dependent proteins in bone metabolism. Annu Rev Nutr. 1988; 8:565-83. PMID: 3060178.
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      153. Lucas PA, Price P, Caplan AI. Chemotactic response of mesenchymal cells, fibroblasts and osteoblast-like cells to bone Gla protein. Bone. 1988; 9(5):319-23. PMID: 3264508.
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      154. Price P, Fraser JD, Metz-Virca G. Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase. Proc Natl Acad Sci U S A. 1987 Dec; 84(23):8335-9. PMID: 3317405; PMCID: PMC299537.
      155. Pan LC, Price P. Ligand-dependent regulation of the 1,25-dihydroxyvitamin D3 receptor in rat osteosarcoma cells. J Biol Chem. 1987 Apr 05; 262(10):4670-5. PMID: 3031030.
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      156. Price P, Kaneda Y. Vitamin K counteracts the effect of warfarin in liver but not in bone. Thromb Res. 1987 Apr 01; 46(1):121-31. PMID: 3495903.
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      157. Wientroub S, Price P, Reddi AH. The dichotomy in the effects of 1,25 dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 on bone gamma-carboxyglutamic acid-containing protein in serum and bone in vitamin D-deficient rats. Calcif Tissue Int. 1987 Mar; 40(3):166-72. PMID: 3105848.
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      158. Price P. Warfarin and bone: implications for rational strategies to selectively antagonize the action of vitamin K in target tissues. Adv Exp Med Biol. 1987; 214:55-66. PMID: 3499056.
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      159. Weiner S, Price P. Disaggregation of bone into crystals. Calcif Tissue Int. 1986 Dec; 39(6):365-75. PMID: 3026591.
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      160. Otawara Y, Price P. Developmental appearance of matrix GLA protein during calcification in the rat. J Biol Chem. 1986 Aug 15; 261(23):10828-32. PMID: 3488316.
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      161. Fanti P, Smith AJ, Price P, Reitz RE, Malluche HH. Effects of parathyroidectomy on circulating levels of 1 alpha,25-dihydroxyvitamin D and bone Gla protein in dialyzed patients. J Clin Endocrinol Metab. 1986 May; 62(5):869-73. PMID: 3485651.
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      162. Spiess YH, Price P, Deftos JL, Manolagas SC. Phenotype-associated changes in the effects of 1,25-dihydroxyvitamin D3 on alkaline phosphatase and bone GLA-protein of rat osteoblastic cells. Endocrinology. 1986 Apr; 118(4):1340-6. PMID: 3485045.
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      163. Price P, Williamson MK. Primary structure of bovine matrix Gla protein, a new vitamin K-dependent bone protein. J Biol Chem. 1985 Dec 05; 260(28):14971-5. PMID: 3877721.
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      164. Calvo MS, Fryer MJ, Laakso KJ, Nissenson RA, Price P, Murray TM, Heath H. Structural requirements for parathyroid hormone action in mature bone. Effects on release of cyclic adenosine monophosphate and bone gamma-carboxyglutamic acid-containing protein from perfused rat hindquarters. J Clin Invest. 1985 Dec; 76(6):2348-54. PMID: 3001148; PMCID: PMC424371.
      165. Pan LC, Williamson MK, Price P. Sequence of the precursor to rat bone gamma-carboxyglutamic acid protein that accumulates in warfarin-treated osteosarcoma cells. J Biol Chem. 1985 Nov 05; 260(25):13398-401. PMID: 3877051.
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      166. Pan LC, Price P. The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6109-13. PMID: 3875856; PMCID: PMC390709.
      167. Nishimoto SK, Price P. The vitamin K-dependent bone protein is accumulated within cultured osteosarcoma cells in the presence of the vitamin K antagonist warfarin. J Biol Chem. 1985 Mar 10; 260(5):2832-6. PMID: 3871773.
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      168. Price P. Vitamin K-dependent formation of bone Gla protein (osteocalcin) and its function. Vitam Horm. 1985; 42:65-108. PMID: 3006348.
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      169. Malluche HH, Faugere MC, Fanti P, Price P. Plasma levels of bone Gla-protein reflect bone formation in patients on chronic maintenance dialysis. Kidney Int. 1984 Dec; 26(6):869-74. PMID: 6335905.
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      170. Pan LC, Price P. The effect of transcriptional inhibitors on the bone gamma-carboxyglutamic acid protein response to 1,25-dihydroxyvitamin D3 in osteosarcoma cells. J Biol Chem. 1984 May 10; 259(9):5844-7. PMID: 6609159.
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      171. Price P, Williamson MK, Sloper SA. 1,25-Dihydroxyvitamin D3 increases citrate secretion from osteosarcoma cells. J Biol Chem. 1984 Feb 25; 259(4):2537-40. PMID: 6607920.
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      172. Price P. Specific tritium labeling of gamma-carboxyglutamic acid residues in proteins. Methods Enzymol. 1984; 107:544-8. PMID: 6390093.
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      173. Price P, Nelson C, Williamson MK. Chemical modification of gamma-carboxyglutamic acid, the vitamin K-dependent amino acid which binds Ca2+. Anal Biochem. 1984 Jan; 136(1):119-26. PMID: 6711802.
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      174. Price P. Decarboxylation of gamma-carboxyglutamic acid residues in proteins. Methods Enzymol. 1984; 107:548-51. PMID: 6503726.
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      175. Price P, Urist MR, Otawara Y. Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone. Biochem Biophys Res Commun. 1983 Dec 28; 117(3):765-71. PMID: 6607731.
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      176. Price P, Sloper SA. Concurrent warfarin treatment further reduces bone mineral levels in 1,25-dihydroxyvitamin D3-treated rats. J Biol Chem. 1983 May 25; 258(10):6004-7. PMID: 6602126.
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      177. Price P. Analysis for gamma-carboxyglutamic acid. Methods Enzymol. 1983; 91:13-7. PMID: 6855572.
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      178. Price P, Williamson MK, Haba T, Dell RB, Jee WS. Excessive mineralization with growth plate closure in rats on chronic warfarin treatment. Proc Natl Acad Sci U S A. 1982 Dec; 79(24):7734-8. PMID: 6984192; PMCID: PMC347422.
      179. Bajaj SP, Price P, Russell WA. Decarboxylation of gamma-carboxyglutamic acid residues in human prothrombin. Stoichiometry of calcium binding to gamma-carboxyglutamic acid in prothrombin. J Biol Chem. 1982 Apr 10; 257(7):3726-31. PMID: 7061506.
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      180. Deftos LJ, Parthemore JG, Price P. Changes in plasma bone GLA protein during treatment of bone disease. Calcif Tissue Int. 1982 Mar; 34(2):121-4. PMID: 6805917.
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      181. Price P, Williamson MK. Effects of warfarin on bone. Studies on the vitamin K-dependent protein of rat bone. J Biol Chem. 1981 Dec 25; 256(24):12754-9. PMID: 6975777.
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      182. Price P, Williamson MK, Lothringer JW. Origin of the vitamin K-dependent bone protein found in plasma and its clearance by kidney and bone. J Biol Chem. 1981 Dec 25; 256(24):12760-6. PMID: 6975778.
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      183. Price P, Lothringer JW, Baukol SA, Reddi AH. Developmental appearance of the vitamin K-dependent protein of bone during calcification. Analysis of mineralizing tissues in human, calf, and rat. J Biol Chem. 1981 Apr 25; 256(8):3781-4. PMID: 6971290.
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      184. Price P, Baukol SA. 1,25-dihydroxyvitamin D3 increases serum levels of the vitamin K-dependent bone protein. Biochem Biophys Res Commun. 1981 Apr 15; 99(3):928-35. PMID: 6972763.
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      185. Price P, Williamson MK, Epstein DJ. Specific tritium incorporation into gamma-carboxyglutamic acid in proteins. The pH dependence of gamma-proton exchange. J Biol Chem. 1981 Feb 10; 256(3):1172-6. PMID: 7005230.
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      186. Price P, Baukol SA. 1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells. J Biol Chem. 1980 Dec 25; 255(24):11660-3. PMID: 6969260.
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      187. Price P, Parthemore JG, Deftos LJ. New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease. J Clin Invest. 1980 Nov; 66(5):878-83. PMID: 6968755; PMCID: PMC371521.
      188. Poser JW, Esch FS, Ling NC, Price P. Isolation and sequence of the vitamin K-dependent protein from human bone. Undercarboxylation of the first glutamic acid residue. J Biol Chem. 1980 Sep 25; 255(18):8685-91. PMID: 6967872.
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      189. Nishimoto SK, Price P. Secretion of the vitamin K-dependent protein of bone by rat osteosarcoma cells. Evidence for an intracellular precursor. J Biol Chem. 1980 Jul 25; 255(14):6579-83. PMID: 6967067.
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      190. Price P, Lothringer JW, Nishimoto SK. Absence of the vitamin K-dependent bone protein in fetal rat mineral. Evidence for another gamma-carboxyglutamic acid-containing component in bone. J Biol Chem. 1980 Apr 10; 255(7):2938-42. PMID: 6965675.
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      191. Price P, Nishimoto SK. Radioimmunoassay for the vitamin K-dependent protein of bone and its discovery in plasma. Proc Natl Acad Sci U S A. 1980 Apr; 77(4):2234-8. PMID: 6966406; PMCID: PMC348687.
      192. Nishimoto SK, Price P. Proof that the gamma-carboxyglutamic acid-containing bone protein is synthesized in calf bone. Comparative synthesis rate and effect of coumadin on synthesis. J Biol Chem. 1979 Jan 25; 254(2):437-41. PMID: 762071.
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      193. Poser JW, Price P. A method for decarboxylation of gamma-carboxyglutamic acid in proteins. Properties of the decarboxylated gamma-carboxyglutamic acid protein from calf bone. J Biol Chem. 1979 Jan 25; 254(2):431-6. PMID: 762070.
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      194. Price P, Poser JW, Raman N. Primary structure of the gamma-carboxyglutamic acid-containing protein from bovine bone. Proc Natl Acad Sci U S A. 1976 Oct; 73(10):3374-5. PMID: 1068450; PMCID: PMC431116.
      195. Price P, Otsuka AA, Poser JW, Kristaponis J, Raman N. Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci U S A. 1976 May; 73(5):1447-51. PMID: 1064018; PMCID: PMC430313.
      196. Price P. The essential role of Ca2+ in the activity of bovine pancreatic deoxyribonuclease. J Biol Chem. 1975 Mar 25; 250(6):1981-6. PMID: 234952.
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      197. Otsuka AS, Price P. Removal of proteases from DNase I by chromatography over agarose with covalently attached lima bean protease inhibitor. Anal Biochem. 1974 Nov; 62(1):180-7. PMID: 4215338.
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      198. Tullis R, Price P. The effect of calcium and magnesium on the ultraviolet spectrum of bovine pancreatic deoxyribonuclease A. J Biol Chem. 1974 Aug 25; 249(16):5033-7. PMID: 4859530.
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      199. Poulos TL, Price P. The involvement of serine and carboxyl groups in the activity of bovine pancreatic deoxyribonuclease A. J Biol Chem. 1974 Mar 10; 249(5):1453-7. PMID: 4361736.
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      200. Oshima RG, Price P. Alkylation of an essential histidine residue in porcine spleen deoxyribonuclease. J Biol Chem. 1973 Nov 10; 248(21):7522-6. PMID: 4355587.
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      201. Price P. Characterization of Ca ++ and Mg ++ binding to bovine pancreatic deoxyribonuclease A. J Biol Chem. 1972 May 10; 247(9):2895-9. PMID: 5063467.
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