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    Orville Kolterman

    Address9500 Gilman Drive #0835
    CA La Jolla 92093
    Phone858-534-5463
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      DIABETES CONTROL AND COMPLICATIONS TRIAL
      NIH/NIDDK U01DK037828Jul 23, 1986 - Jun 30, 1994
      Role: Principal Investigator

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Riddle MC, Yuen KC, de Bruin TW, Herrmann K, Xu J, Öhman P, Kolterman O. Fixed ratio dosing of pramlintide with regular insulin before a standard meal in patients with type 1 diabetes. Diabetes Obes Metab. 2015 Sep; 17(9):904-7. PMID: 26040429.
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      2. MacConell L, Gurney K, Malloy J, Zhou M, Kolterman O. Safety and tolerability of exenatide once weekly in patients with type 2 diabetes: an integrated analysis of 4,328 patients. Diabetes Metab Syndr Obes. 2015; 8:241-53. PMID: 26056482.
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      3. Miao F, Chen Z, Genuth S, Paterson A, Zhang L, Wu X, Li SM, Cleary P, Riggs A, Harlan DM, Lorenzi G, Kolterman O, Sun W, Lachin JM, Natarajan R. Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes. Diabetes. 2014 May; 63(5):1748-62. PMID: 24458354.
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      4. Micheletto F, Dalla Man C, Kolterman O, Chiquette E, Herrmann K, Schirra J, Kovatchev B, Cobelli C. In silico design of optimal ratio for co-administration of pramlintide and insulin in type 1 diabetes. Diabetes Technol Ther. 2013 Oct; 15(10):802-9. PMID: 23865841.
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      5. Herrmann K, Frias JP, Edelman SV, Lutz K, Shan K, Chen S, Maggs D, Kolterman O. Pramlintide improved measures of glycemic control and body weight in patients with type 1 diabetes mellitus undergoing continuous subcutaneous insulin infusion therapy. Postgrad Med. 2013 May; 125(3):136-44. PMID: 23748514.
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      6. Riddle M, Frias J, Zhang B, Maier H, Brown C, Lutz K, Kolterman O. Pramlintide improved glycemic control and reduced weight in patients with type 2 diabetes using basal insulin. Diabetes Care. 2007 Nov; 30(11):2794-9. PMID: 17698615.
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      7. Grasela TH, Dement CW, Kolterman O, Fineman MS, Grasela DM, Honig P, Antal EJ, Bjornsson TD, Loh E. Pharmacometrics and the transition to model-based development. Clin Pharmacol Ther. 2007 Aug; 82(2):137-42. PMID: 17632539.
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      8. Edelman SV, Garg S, Kolterman O. Is pramlintide a safe and effective adjunct therapy for patients with type 1 diabetes? Nat Clin Pract Endocrinol Metab. 2007 May; 3(5):E1; discussion E2. PMID: 17452962.
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      9. Marrero DG, Crean J, Zhang B, Kellmeyer T, Gloster M, Herrmann K, Rubin R, Fineberg N, Kolterman O. Effect of adjunctive pramlintide treatment on treatment satisfaction in patients with type 1 diabetes. Diabetes Care. 2007 Feb; 30(2):210-6. PMID: 17259483.
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      10. Edelman S, Garg S, Frias J, Maggs D, Wang Y, Zhang B, Strobel S, Lutz K, Kolterman O. A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes. Diabetes Care. 2006 Oct; 29(10):2189-95. PMID: 17003291.
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      11. Schnabel CA, Wintle M, Kolterman O. Metabolic effects of the incretin mimetic exenatide in the treatment of type 2 diabetes. Vasc Health Risk Manag. 2006; 2(1):69-77. PMID: 17319471.
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      12. Amiel SA, Heller SR, Macdonald IA, Schwartz SL, Klaff LJ, Ruggles JA, Weyer C, Kolterman O, Maggs DG. The effect of pramlintide on hormonal, metabolic or symptomatic responses to insulin-induced hypoglycaemia in patients with type 1 diabetes. Diabetes Obes Metab. 2005 Sep; 7(5):504-16. PMID: 16050943.
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      13. Weyer C, Fineman MS, Strobel S, Shen L, Data J, Kolterman O, Sylvestri MF. Properties of pramlintide and insulin upon mixing. Am J Health Syst Pharm. 2005 Apr 15; 62(8):816-22. PMID: 15821274.
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      14. Ratner R, Whitehouse F, Fineman MS, Strobel S, Shen L, Maggs DG, Kolterman O, Weyer C. Adjunctive therapy with pramlintide lowers HbA1c without concomitant weight gain and increased risk of severe hypoglycemia in patients with type 1 diabetes approaching glycemic targets. Exp Clin Endocrinol Diabetes. 2005 Apr; 113(4):199-204. PMID: 15891954.
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      15. Kolterman O, Kim DD, Shen L, Ruggles JA, Nielsen LL, Fineman MS, Baron AD. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus. Am J Health Syst Pharm. 2005 Jan 15; 62(2):173-81. PMID: 15700891.
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      16. Ratner RE, Dickey R, Fineman M, Maggs DG, Shen L, Strobel SA, Weyer C, Kolterman O. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov; 21(11):1204-12. PMID: 15498087.
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      17. Heise T, Heinemann L, Heller S, Weyer C, Wang Y, Strobel S, Kolterman O, Maggs D. Effect of pramlintide on symptom, catecholamine, and glucagon responses to hypoglycemia in healthy subjects. Metabolism. 2004 Sep; 53(9):1227-32. PMID: 15334389.
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      18. Veitenhansl M, Stegner K, Hierl FX, Dieterle C, Feldmeier H, Gutt B, Landgraf R, Garrow AP, Vileikyte L, Findlow A, Waterman C, Boulton AJ, Shankhdhar K, Shankhdhar L, Shankhdhar U, Petrova NL, Foster AV, Edmonds ME, Ferraresi R, Caravaggi C, De Giglio R, Cavaiani P, Pogliaghi I, Sommariva E, Katz IA, Harlan A, Miranda-Palma B, Prieto-Sanchez L, Armstrong DG, Bowker JH, Mizel MS, Cernea S, Wohlgelernter J, Kidron M, Modi P, Raz I, Arbit E, Nosek L, Kapitza C, Beckett P, Gelfand R, Goldberg M, Heise T, Testa MA, Turner RR, Hayes JF, Scranton RE, Simonson DC, Yang YW, Hsu YJ, Naujok O, Francini F, Jörns A, Tiedge M, Lenzen S, Abdel-Wahab YH, Marenah L, Orr DF, Shaw C, Flatt PR, Chokkalingam K, Mansell PI, Clausen P, Ekbom P, Damm P, Feldt-Rasmussen U, Nielsen B, Mathiesen ER, Feldt-Rasmussen B, Dewan S, Da Silva N, Ternan PM, Leong KS, Wilding JP, Asatiani N, Kurashvili R, Dundua M, Shelestova E, Pagava K, Ramazashvili M, Hod M, Smirnov S, Petersen JL, Justesen TI, Ringholm Nielsen L, Müller C, Højlund K, Wensaas A, Kase ET, Aas V, Rustan AC, Thoresen GH, Levin K, Beck-Nielsen H, Gaster M, Im SS, Kang SY, Kim SY, Ahn YH, Lihn AS, Schmoll D, Werner T, Kienitz A, Meyer M, Barthel A, Ailett F, Sutherland C, Walther R, Grempler R, Sasson S, Reich R, Tenenbaum T, Alpert E, Anfossi G, Russo I, Traversa M, Massucco P, Mattiello L, Doronzo G, Trovati M, Lally S, Tan CY, Owens D, Tomkin GH, Porchay I, Péan F, Bellili N, Betoulle D, Balkau B, Tichet J, Marre M, Fumeron F. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 2004 Aug; 47(Suppl 1):A1-A464. PMID: 27770180.
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      19. Hollander P, Maggs DG, Ruggles JA, Fineman M, Shen L, Kolterman O, Weyer C. Effect of pramlintide on weight in overweight and obese insulin-treated type 2 diabetes patients. Obes Res. 2004 Apr; 12(4):661-8. PMID: 15090634.
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      20. Maggs DG, Fineman M, Kornstein J, Burrell T, Schwartz S, Wang Y, Ruggles JA, Kolterman O, Weyer C. Pramlintide reduces postprandial glucose excursions when added to insulin lispro in subjects with type 2 diabetes: a dose-timing study. Diabetes Metab Res Rev. 2004 Jan-Feb; 20(1):55-60. PMID: 14737746.
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      21. Maggs D, Shen L, Strobel S, Brown D, Kolterman O, Weyer C. Effect of pramlintide on A1C and body weight in insulin-treated African Americans and Hispanics with type 2 diabetes: a pooled post hoc analysis. Metabolism. 2003 Dec; 52(12):1638-42. PMID: 14669170.
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      22. Hollander P, Ratner R, Fineman M, Strobel S, Shen L, Maggs D, Kolterman O, Weyer C. Addition of pramlintide to insulin therapy lowers HbA1c in conjunction with weight loss in patients with type 2 diabetes approaching glycaemic targets. Diabetes Obes Metab. 2003 Nov; 5(6):408-14. PMID: 14617226.
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      23. Weyer C, Gottlieb A, Kim DD, Lutz K, Schwartz S, Gutierrez M, Wang Y, Ruggles JA, Kolterman O, Maggs DG. Pramlintide reduces postprandial glucose excursions when added to regular insulin or insulin lispro in subjects with type 1 diabetes: a dose-timing study. Diabetes Care. 2003 Nov; 26(11):3074-9. PMID: 14578242.
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      24. Kolterman O, Buse JB, Fineman MS, Gaines E, Heintz S, Bicsak TA, Taylor K, Kim D, Aisporna M, Wang Y, Baron AD. Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab. 2003 Jul; 88(7):3082-9. PMID: 12843147.
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      25. Hollander PA, Levy P, Fineman MS, Maggs DG, Shen LZ, Strobel SA, Weyer C, Kolterman O. Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial. Diabetes Care. 2003 Mar; 26(3):784-90. PMID: 12610038.
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      26. Levetan C, Want LL, Weyer C, Strobel SA, Crean J, Wang Y, Maggs DG, Kolterman O, Chandran M, Mudaliar SR, Henry RR. Impact of pramlintide on glucose fluctuations and postprandial glucose, glucagon, and triglyceride excursions among patients with type 1 diabetes intensively treated with insulin pumps. Diabetes Care. 2003 Jan; 26(1):1-8. PMID: 12502651.
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      27. Fineman M, Weyer C, Maggs DG, Strobel S, Kolterman O. The human amylin analog, pramlintide, reduces postprandial hyperglucagonemia in patients with type 2 diabetes mellitus. Horm Metab Res. 2002 Sep; 34(9):504-8. PMID: 12384827.
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      28. Fineman MS, Koda JE, Shen LZ, Strobel SA, Maggs DG, Weyer C, Kolterman O. The human amylin analog, pramlintide, corrects postprandial hyperglucagonemia in patients with type 1 diabetes. Metabolism. 2002 May; 51(5):636-41. PMID: 11979398.
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      29. Whitehouse F, Kruger DF, Fineman M, Shen L, Ruggles JA, Maggs DG, Weyer C, Kolterman O. A randomized study and open-label extension evaluating the long-term efficacy of pramlintide as an adjunct to insulin therapy in type 1 diabetes. Diabetes Care. 2002 Apr; 25(4):724-30. PMID: 11919132.
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      30. Ratner RE, Want LL, Fineman MS, Velte MJ, Ruggles JA, Gottlieb A, Weyer C, Kolterman O. Adjunctive therapy with the amylin analogue pramlintide leads to a combined improvement in glycemic and weight control in insulin-treated subjects with type 2 diabetes. Diabetes Technol Ther. 2002; 4(1):51-61. PMID: 12017421.
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      31. Weyer C, Maggs DG, Young AA, Kolterman O. Amylin replacement with pramlintide as an adjunct to insulin therapy in type 1 and type 2 diabetes mellitus: a physiological approach toward improved metabolic control. Curr Pharm Des. 2001 Sep; 7(14):1353-73. PMID: 11472273.
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      32. Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F. 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia. 1999 Aug; 42(Suppl 1):A1-A330. PMID: 27770183.
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      33. Young A, Kolterman O, Hall J. Amylin innocent in essential hypertension? Diabetologia. 1999 Aug; 42(8):1029. PMID: 10491767.
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      34. Nyholm B, Orskov L, Hove KY, Gravholt CH, Møller N, Alberti KG, Moyses C, Kolterman O, Schmitz O. The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus. Metabolism. 1999 Jul; 48(7):935-41. PMID: 10421239.
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      35. Thompson RG, Pearson L, Schoenfeld SL, Kolterman O. Pramlintide, a synthetic analog of human amylin, improves the metabolic profile of patients with type 2 diabetes using insulin. The Pramlintide in Type 2 Diabetes Group. Diabetes Care. 1998 Jun; 21(6):987-93. PMID: 9614619.
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      36. Thompson RG, Pearson L, Kolterman O. Effects of 4 weeks' administration of pramlintide, a human amylin analogue, on glycaemia control in patients with IDDM: effects on plasma glucose profiles and serum fructosamine concentrations. Diabetologia. 1997 Nov; 40(11):1278-85. PMID: 9389419.
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      37. Thompson RG, Gottlieb A, Organ K, Koda J, Kisicki J, Kolterman O. Pramlintide: a human amylin analogue reduced postprandial plasma glucose, insulin, and C-peptide concentrations in patients with type 2 diabetes. Diabet Med. 1997 Jul; 14(7):547-55. PMID: 9223392.
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      38. Kolterman O. Amylin and glycaemic regulation: a possible role for the human amylin analogue pramlintide. Diabet Med. 1997 Jun; 14 Suppl 2:S35-8. PMID: 9212328.
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      39. Moyses C, Young A, Kolterman O. Modulation of gastric emptying as a therapeutic approach to glycaemic control. Diabet Med. 1996 Sep; 13(9 Suppl 5):S34-8. PMID: 8894469.
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      40. Hanson CL, De Guire MJ, Schinkel AM, Kolterman O, Goodman JP, Buckingham BA. Self-care behaviors in insulin-dependent diabetes: evaluative tools and their associations with glycemic control. J Pediatr Psychol. 1996 Aug; 21(4):467-82. PMID: 8863457.
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      41. Dimsdale JE, Kolterman O, Koda J, Nelesen R. Effect of race and hypertension on plasma amylin concentrations. Hypertension. 1996 Jun; 27(6):1273-6. PMID: 8641735.
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      42. Kolterman O, Schwartz S, Corder C, Levy B, Klaff L, Peterson J, Gottlieb A. Effect of 14 days' subcutaneous administration of the human amylin analogue, pramlintide (AC137), on an intravenous insulin challenge and response to a standard liquid meal in patients with IDDM. Diabetologia. 1996 Apr; 39(4):492-9. PMID: 8778001.
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      43. Colburn WA, Gottlieb AB, Koda J, Kolterman O. Pharmacokinetics and pharmacodynamics of AC137 (25,28,29 tripro-amylin, human) after intravenous bolus and infusion doses in patients with insulin-dependent diabetes. J Clin Pharmacol. 1996 Jan; 36(1):13-24. PMID: 8932539.
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      44. Hanson CL, De Guire MJ, Schinkel AM, Kolterman O. Empirical validation for a family-centered model of care. Diabetes Care. 1995 Oct; 18(10):1347-56. PMID: 8721936.
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      45. Cutler DL, Gray CG, Park SW, Hickman MG, Bell JM, Kolterman O. Low-carbohydrate diet alters intracellular glucose metabolism but not overall glucose disposal in exercise-trained subjects. Metabolism. 1995 Oct; 44(10):1264-70. PMID: 7476282.
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      46. Kolterman O, Gottlieb A, Moyses C, Colburn W. Reduction of postprandial hyperglycemia in subjects with IDDM by intravenous infusion of AC137, a human amylin analogue. Diabetes Care. 1995 Aug; 18(8):1179-82. PMID: 7587855.
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      47. Kolterman O. Type II diabetes: who has the keys? J Lab Clin Med. 1993 Apr; 121(4):534-5. PMID: 8454933.
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      48. Wahlstrom HE, Akimoto R, Endres D, Kolterman O, Moossa AR. Recovery and hypersecretion of insulin and reversal of insulin resistance after withdrawal of short-term cyclosporine treatment. Transplantation. 1992 Jun; 53(6):1190-5. PMID: 1604471.
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      49. Kolterman O. Glyburide in non-insulin-dependent diabetes: an update. Clin Ther. 1992 Mar-Apr; 14(2):196-213. PMID: 1611644.
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      50. Kusari J, Takata Y, Hatada E, Freidenberg G, Kolterman O, Olefsky JM. Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles. J Biol Chem. 1991 Mar 15; 266(8):5260-7. PMID: 2002058.
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      51. Solt VB, Brown MR, Kennedy B, Kolterman O, Ziegler MG. Elevated insulin, norepinephrine, and neuropeptide Y in hypertension. Am J Hypertens. 1990 Nov; 3(11):823-8. PMID: 2261148.
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      52. Wahlstrom HE, Lavelle-Jones M, Endres D, Akimoto R, Kolterman O, Moossa AR. Inhibition of insulin release by cyclosporine and production of peripheral insulin resistance in the dog. Transplantation. 1990 Mar; 49(3):600-4. PMID: 2180152.
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      53. Serpa MD, Ting J, Lee MP, Colwell B, Kolterman O. Computerized ambulatory-care pharmacy information system for direct order entry by prescribers. Am J Hosp Pharm. 1990 Feb; 47(2):361-3. PMID: 2309726.
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      54. Garvey WT, Kolterman O. Correlation of in vivo and in vitro actions of insulin in obesity and noninsulin-dependent diabetes mellitus: role of the glucose transport system. Diabetes Metab Rev. 1988 Sep; 4(6):543-69. PMID: 3065009.
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      55. Garvey WT, Olefsky JM, Rubenstein AH, Kolterman O. Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion. Diabetes. 1988 May; 37(5):590-9. PMID: 3282946.
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      56. Wright KS, Beck-Nielsen H, Kolterman O, Mandarino LJ. Decreased activation of skeletal muscle glycogen synthase by mixed-meal ingestion in NIDDM. Diabetes. 1988 Apr; 37(4):436-40. PMID: 2837418.
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      57. Mandarino LJ, Wright KS, Verity LS, Nichols J, Bell JM, Kolterman O, Beck-Nielsen H. Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism. J Clin Invest. 1987 Sep; 80(3):655-63. PMID: 2957389.
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      58. Moore TR, Hollingsworth DR, Kolterman O, Nager C. Continuous subcutaneous insulin infusion in an obese insulin-resistant pregnant woman with type II diabetes: accelerated fetal growth and neonatal complications. Obstet Gynecol. 1987 Sep; 70(3 Pt 2):480-5. PMID: 3627609.
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      59. Baron AD, Eckel RH, Schmeiser L, Kolterman O. The effect of short-term alpha-glucosidase inhibition on carbohydrate and lipid metabolism in type II (noninsulin-dependent) diabetics. Metabolism. 1987 May; 36(5):409-15. PMID: 3553848.
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      60. Lavelle-Jones M, Scott MH, Kolterman O, Moossa AR, Olefsky JM. Non-insulin-mediated glucose uptake predominates in postabsorptive dogs. Am J Physiol. 1987 May; 252(5 Pt 1):E660-6. PMID: 2883896.
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      61. Kolterman O. The impact of sulfonylureas on hepatic glucose metabolism in type II diabetics. Diabetes Metab Rev. 1987 Apr; 3(2):399-414. PMID: 3552528.
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      62. Baron AD, Schaeffer L, Shragg P, Kolterman O. Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics. Diabetes. 1987 Mar; 36(3):274-83. PMID: 2879757.
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      63. Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Selective suppression of hepatic glucose output by human proinsulin in the dog. Am J Physiol. 1987 Feb; 252(2 Pt 1):E230-6. PMID: 2881485.
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      64. Mandarino LJ, Madar Z, Kolterman O, Bell JM, Olefsky JM. Adipocyte glycogen synthase and pyruvate dehydrogenase in obese and type II diabetic subjects. Am J Physiol. 1986 Oct; 251(4 Pt 1):E489-96. PMID: 3094377.
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      65. Shoelson SE, Marshall S, Horikoshi H, Kolterman O, Rubenstein AH, Olefsky JM. Antiinsulin receptor antibodies in an insulin-dependent diabetic may arise as autoantiidiotypes. J Clin Endocrinol Metab. 1986 Jul; 63(1):56-61. PMID: 3486878.
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      66. Glauber HS, Revers RR, Henry R, Schmeiser L, Wallace P, Kolterman O, Cohen RM, Rubenstein AH, Galloway JA, Frank BH. In vivo deactivation of proinsulin action on glucose disposal and hepatic glucose production in normal man. Diabetes. 1986 Mar; 35(3):311-7. PMID: 3512341.
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      67. Crapo PA, Kolterman O, Henry RR. Metabolic consequence of two-week fructose feeding in diabetic subjects. Diabetes Care. 1986 Mar-Apr; 9(2):111-9. PMID: 3516605.
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      68. Henry RR, Wiest-Kent TA, Scheaffer L, Kolterman O, Olefsky JM. Metabolic consequences of very-low-calorie diet therapy in obese non-insulin-dependent diabetic and nondiabetic subjects. Diabetes. 1986 Feb; 35(2):155-64. PMID: 3510922.
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      69. Baron AD, Kolterman O, Bell J, Mandarino LJ, Olefsky JM. Rates of noninsulin-mediated glucose uptake are elevated in type II diabetic subjects. J Clin Invest. 1985 Nov; 76(5):1782-8. PMID: 2865274.
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      70. Olefsky JM, Ciaraldi TP, Kolterman O. Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes. Am J Med. 1985 Sep 20; 79(3B):12-22. PMID: 3901744.
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      71. Kolterman O. Longitudinal evaluation of the effects of sulfonylurea therapy in subjects with type II diabetes mellitus. Am J Med. 1985 Sep 20; 79(3B):23-33. PMID: 3931459.
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      72. Garvey WT, Revers RR, Kolterman O, Rubenstein AH, Olefsky JM. Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus. J Clin Endocrinol Metab. 1985 Mar; 60(3):559-68. PMID: 3882736.
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      73. Fink RI, Revers RR, Kolterman O, Olefsky JM. The metabolic clearance of insulin and the feedback inhibition of insulin secretion are altered with aging. Diabetes. 1985 Mar; 34(3):275-80. PMID: 3882495.
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      74. Garvey WT, Olefsky JM, Griffin J, Hamman RF, Kolterman O. The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus. Diabetes. 1985 Mar; 34(3):222-34. PMID: 3882489.
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      75. Olefsky JM, Revers RR, Prince M, Henry RR, Garvey WT, Scarlett JA, Kolterman O. Insulin resistance in non-insulin dependent (type II) and insulin dependent (type I) diabetes mellitus. Adv Exp Med Biol. 1985; 189:176-205. PMID: 3898763.
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      76. Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Bergenstal R, Polonsky K, Jaspan J, Rubenstein A, Frank B. The effects of biosynthetic human proinsulin on carbohydrate metabolism. Diabetes. 1984 Aug; 33(8):762-70. PMID: 6378699.
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      77. Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Rubenstein A, Frank B, Galloway J, Olefsky JM. Biosynthetic human insulin and proinsulin have additive but not synergistic effects on total body glucose disposal. J Clin Endocrinol Metab. 1984 Jun; 58(6):1094-8. PMID: 6373809.
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      78. Bergenstal RM, Cohen RM, Lever E, Polonsky K, Jaspan J, Blix PM, Revers R, Olefsky JM, Kolterman O, Steiner K. The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. J Clin Endocrinol Metab. 1984 Jun; 58(6):973-9. PMID: 6373814.
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      79. Kolterman O, Olefsky JM. The impact of sulfonylurea treatment upon the mechanisms responsible for the insulin resistance in type II diabetes. Diabetes Care. 1984 May-Jun; 7 Suppl 1:81-8. PMID: 6376033.
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      80. Fink RI, Kolterman O, Olefsky JM. The physiological significance of the glucose intolerance of aging. J Gerontol. 1984 May; 39(3):273-8. PMID: 6371116.
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      81. Crapo PA, Kolterman O. The metabolic effects of 2-week fructose feeding in normal subjects. Am J Clin Nutr. 1984 Apr; 39(4):525-34. PMID: 6369956.
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      82. Kolterman O, Gray RS, Shapiro G, Scarlett JA, Griffin J, Olefsky JM. The acute and chronic effects of sulfonylurea therapy in type II diabetic subjects. Diabetes. 1984 Apr; 33(4):346-54. PMID: 6423429.
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      83. Fink RI, Kolterman O, Kao M, Olefsky JM. The role of the glucose transport system in the postreceptor defect in insulin action associated with human aging. J Clin Endocrinol Metab. 1984 Apr; 58(4):721-5. PMID: 6699133.
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      84. Revers RR, Fink R, Griffin J, Olefsky JM, Kolterman O. Influence of hyperglycemia on insulin's in vivo effects in type II diabetes. J Clin Invest. 1984 Mar; 73(3):664-72. PMID: 6368585.
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      85. Revers RR, Kolterman O, Scarlett JA, Gray RS, Olefsky JM. Lack of in vivo insulin resistance in controlled insulin-dependent, type I, diabetic patients. J Clin Endocrinol Metab. 1984 Feb; 58(2):353-8. PMID: 6363437.
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      86. Berhanu P, Kolterman O, Baron A, Tsai P, Olefsky JM, Brandenburg D. Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing. J Clin Invest. 1983 Dec; 72(6):1958-70. PMID: 6358259.
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      87. Revers RR, Kolterman O, Olefsky JM. Relationship between serum glucose level and the metabolic clearance rate of glucose in non-insulin-dependent diabetes mellitus. Diabetes. 1983 Jul; 32(7):627-32. PMID: 6345242.
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      88. Fink RI, Kolterman O, Griffin J, Olefsky JM. Mechanisms of insulin resistance in aging. J Clin Invest. 1983 Jun; 71(6):1523-35. PMID: 6345584.
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      89. Scarlett JA, Kolterman O, Ciaraldi TP, Kao M, Olefsky JM. Insulin treatment reverses the postreceptor defect in adipocyte 3-O-methylglucose transport in type II diabetes mellitus. J Clin Endocrinol Metab. 1983 Jun; 56(6):1195-201. PMID: 6341390.
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      90. Kolterman O, Prince MJ, Olefsky JM. Insulin resistance in noninsulin-dependent diabetes mellitus: impact of sulfonylurea agents in vivo and in vitro. Am J Med. 1983 Jan 17; 74(1A):82-101. PMID: 6401923.
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      91. Ciaraldi TP, Kolterman O, Scarlett JA, Kao M, Olefsky JM. Role of glucose transport in the postreceptor defect of non-insulin-dependent diabetes mellitus. Diabetes. 1982 Nov; 31(11):1016-22. PMID: 6757010.
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      92. Gray RS, Scarlett JA, Griffin J, Olefsky JM, Kolterman O. In vivo deactivation of peripheral, hepatic, and pancreatic insulin action in man. Diabetes. 1982 Oct; 31(10):929-36. PMID: 6759226.
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      93. Crapo PA, Scarlett JA, Kolterman O, Sanders LR, Hofeldt FD, Olefsky JM. The effects of oral fructose, sucrose, and glucose in subjects with reactive hypoglycemia. Diabetes Care. 1982 Sep-Oct; 5(5):512-7. PMID: 6765227.
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      94. Crapo PA, Scarlett JA, Kolterman O. Comparison of the metabolic responses to fructose and sucrose sweetened foods. Am J Clin Nutr. 1982 Aug; 36(2):256-61. PMID: 7048890.
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      95. Scarlett JA, Kolterman O, Moore P, Saekow M, Insel J, Griffin J, Mako M, Rubenstein AH, Olefsky JM. Insulin resistance and diabetes due to a genetic defect in insulin receptors. J Clin Endocrinol Metab. 1982 Jul; 55(1):123-31. PMID: 7042734.
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      96. Kolterman O, Scarlett JA, Olefsky JM. Insulin resistance in non-insulin-dependent, type II diabetes mellitus. Clin Endocrinol Metab. 1982 Jul; 11(2):363-88. PMID: 6754161.
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      97. Olefsky JM, Kolterman O, Scarlett JA. Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus. Am J Physiol. 1982 Jul; 243(1):E15-30. PMID: 7046470.
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      98. Scarlett JA, Gray RS, Griffin J, Olefsky JM, Kolterman O. Insulin treatment reverses the insulin resistance of type II diabetes mellitus. Diabetes Care. 1982 Jul-Aug; 5(4):353-63. PMID: 6759075.
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      99. Ciaraldi TP, Kolterman O, Olefsky JM. Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity. J Clin Invest. 1981 Oct; 68(4):875-80. PMID: 7026616.
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      100. Kolterman O, Gray RS, Griffin J, Burstein P, Insel J, Scarlett JA, Olefsky JM. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. J Clin Invest. 1981 Oct; 68(4):957-69. PMID: 7287908.
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      101. Moore P, Kolterman O, Weyant J, Olefsky JM. Insulin binding in human pregnancy: comparisons to the postpartum, luteal, and follicular states. J Clin Endocrinol Metab. 1981 May; 52(5):937-41. PMID: 7014589.
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      102. Crapo PA, Insel J, Sperling M, Kolterman O. Comparison of serum glucose, insulin, and glucagon responses to different types of complex carbohydrate in noninsulin-dependent diabetic patients. Am J Clin Nutr. 1981 Feb; 34(2):184-90. PMID: 7010982.
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      103. Olefsky JM, Kolterman O. Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes. Am J Med. 1981 Jan; 70(1):151-68. PMID: 7006388.
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      104. Kolterman O, Olefsky JM, Kurahara C, Taylor K. A defect in cell-mediated immune function in insulin-resistant diabetic and obese subjects. J Lab Clin Med. 1980 Sep; 96(3):535-43. PMID: 6995542.
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      105. Crapo PA, Kolterman O, Olefsky JM. Effects of oral fructose in normal, diabetic, and impaired glucose tolerance subjects. Diabetes Care. 1980 Sep-Oct; 3(5):575-82. PMID: 7002511.
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      106. Crapo PA, Kolterman O, Waldeck N, Reaven GM, Olefsky JM. Postprandial hormonal responses to different types of complex carbohydrate in individuals with impaired glucose tolerance. Am J Clin Nutr. 1980 Aug; 33(8):1723-8. PMID: 6996472.
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      107. Greenfield M, Kolterman O, Olefsky J, Reaven GM. Mechanism of hypertriglyceridaemia in diabetic patients with fasting hyperglycaemia. Diabetologia. 1980 Jun; 18(6):441-6. PMID: 7418956.
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      108. Kolterman O, Insel J, Saekow M, Olefsky JM. Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects. J Clin Invest. 1980 Jun; 65(6):1272-84. PMID: 6997333.
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      109. Insel JR, Kolterman O, Saekow M, Olefsky JM. Short-term regulation of insulin receptor affinity in man. Diabetes. 1980 Feb; 29(2):132-9. PMID: 6986298.
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      110. Given BD, Mako ME, Tager HS, Baldwin D, Markese J, Rubenstein AH, Olefsky J, Kobayashi M, Kolterman O, Poucher R. Diabetes due to secretion of an abnormal insulin. N Engl J Med. 1980 Jan 17; 302(3):129-35. PMID: 7350438.
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      111. Olefsky JM, Kolterman O. Pancreas. Clin Endocrinol Metab. 1979 Nov; 8(3):579-601. PMID: 389492.
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      112. Tager H, Given B, Baldwin D, Mako M, Markese J, Rubenstein A, Olefsky J, Kobayashi M, Kolterman O, Poucher R. A structurally abnormal insulin causing human diabetes. Nature. 1979 Sep 13; 281(5727):122-5. PMID: 381941.
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      113. Kolterman O, Greenfield M, Reaven GM, Saekow M, Olefsky JM. Effect of a high carbohydrate diet on insulin binding to adipocytes and on insulin action in vivo in man. Diabetes. 1979 Aug; 28(8):731-6. PMID: 446930.
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      114. Ciaraldi TP, Kolterman O, Siegel JA, Olefsky JM. Insulin-stimulated glucose transport in human adipocytes. Am J Physiol. 1979 Jun; 236(6):E621-5. PMID: 443417.
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      115. Kolterman O, Saekow M, Olefsky JM. The effects of acute and chronic starvation on insulin binding to isolated human adipocytes. J Clin Endocrinol Metab. 1979 May; 48(5):836-42. PMID: 429529.
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      116. Kolterman O, Reaven GM, Olefsky JM. Relationship between in vivo insulin resistance and decreased insulin receptors in obese man. J Clin Endocrinol Metab. 1979 Mar; 48(3):487-94. PMID: 429500.
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      117. Davis BM, Bernstein R, Kolterman O, Olefsky JM, Reaven GM. Defect in glucose removal in nonketotic diabetic patients with fasting hyperglycemia. Diabetes. 1979 Jan; 28(1):32-4. PMID: 569610.
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      118. Greenfield M, Kolterman O, Olefsky JM, Reaven GM. The effect of ten days of fasting on various aspects of carbohydrate metabolism in obese diabetic subjects with significant fasting hyperglycemia. Metabolism. 1978 Dec; 27(12 Suppl 2):1839-52. PMID: 723636.
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      119. Reaven EP, Kolterman O, Reaven GM. Ultrastructural and physiological evidence for corticosteroid-induced alterations in hepatic production of very low density lipoprotein particles. J Lipid Res. 1974 Jan; 15(1):74-83. PMID: 4359541.
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      120. Stern MP, Kolterman O, Fries JF, McDevitt HO, Reaven GM. Adrenocortical steroid treatment of rheumatic diseases. Effects on lipid metabolism. Arch Intern Med. 1973 Jul; 132(1):97-101. PMID: 4541465.
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      121. Stern MP, Kolterman O, McDevitt H, Reaven GM. Acquired type 3 hyperlipoproteinemia. Report of three cases associated with systemic lupus erythematosus and diabetic ketoacidosis. Arch Intern Med. 1972 Dec; 130(6):817-21. PMID: 4628294.
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