Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Nicholas Spitzer

    TitleResearcher
    SchoolUniversity of California, San Diego
    DepartmentNeurobiology
    Address9500 Gilman Drive #0357
    CA La Jolla 92093
    Phone858-534-2456
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Neurotransmitter Switching and Its Function in Hippocampal Plasticity
      NIH/NIMH R21MH105706Sep 10, 2014 - Aug 31, 2016
      Role: Principal Investigator
      Analysis of Activity Dependent Mechanisms of Neuronal Differentiation
      NIH/NINDS R01NS057690Dec 1, 2006 - Jan 31, 2019
      Role: Principal Investigator
      Mechanisms of Calcium Transients in Neuronal Development
      NIH/NIMH R01MH074702Jun 1, 2006 - Aug 31, 2011
      Role: Principal Investigator
      Mechanisms of Calcium Transients in Neuronal Development
      NIH/NIMH R56MH074702Sep 25, 2005 - May 31, 2006
      Role: Principal Investigator
      MECHANISMS OF GENERATION OF GROWTH CONE CALCIUM WAVES
      NIH/NINDS R01NS037002Sep 8, 1998 - Aug 31, 2002
      Role: Principal Investigator
      TARGET GENES OF TRANSCRIPTION FACTORS IN XENOPUS
      NIH/FIC F06TW001998Aug 17, 1994
      Role: Principal Investigator
      INDUCTION AND COMPENTENCE IN THE RETINA
      NIH/NEI R01EY010422Jul 1, 1994 - Jun 30, 1998
      Role: Principal Investigator
      FORMATION OF NEURAL PATHWAYS IN THE EMBRYO
      NIH/NEI R01EY010770Jul 1, 1994 - Jun 30, 1997
      Role: Principal Investigator
      MOLECULAR AND BIOPHYSICAL ASPECTS OF NEURONAL SIGNALING
      NIH/NINDS P01NS025916Mar 1, 1988 - Feb 28, 1997
      Role: Co-Investigator
      FORMATION OF NEURAL PATHWAYS IN THE AMPHIBIAN EMBRYO
      NIH/NICHD K04HD000528Jul 1, 1983 - Jun 30, 1988
      Role: Principal Investigator
      Neural Circuits Postdoctoral Training Program
      NIH/NINDS T32NS007220Jul 1, 1982 - Jun 30, 2017
      Role: Principal Investigator
      FORMATION OF NEURAL PATHWAYS IN THE EMBRYO
      NIH/NICHD R01HD014490Sep 30, 1980 - May 31, 1993
      Role: Principal Investigator
      Development of Neurons
      NIH/NINDS R01NS015918Jan 1, 1980 - Mar 31, 2018
      Role: Principal Investigator
      Development of Neurons
      NIH/NINDS R56NS015918Jan 1, 1980 - Jun 30, 2014
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Dulcis D, Lippi G, Stark CJ, Do LH, Berg DK, Spitzer N. Neurotransmitter Switching Regulated by miRNAs Controls Changes in Social Preference. Neuron. 2017 Sep 13; 95(6):1319-1333.e5. PMID: 28867550.
        View in: PubMed
      2. Spitzer N. Neurotransmitter Switching in the Developing and Adult Brain. Annu Rev Neurosci. 2017 Mar 06. PMID: 28301776.
        View in: PubMed
      3. Aumann TD, Raabus M, Tomas D, Prijanto A, Churilov L, Spitzer N, Horne MK. Differences in Number of Midbrain Dopamine Neurons Associated with Summer and Winter Photoperiods in Humans. PLoS One. 2016; 11(7):e0158847. PMID: 27428306; PMCID: PMC4948786.
        View in: PubMed, PubMed Central
      4. Spitzer N. DEVELOPMENTAL NEUROSCIENCE. Neurotransmitter-tailored dendritic trees. Science. 2015 Oct 30; 350(6260):510-1. PMID: 26516267.
        View in: PubMed
      5. Vincent P, Spitzer N. Editorial: Dynamics of cyclic nucleotide signaling in neurons. Front Cell Neurosci. 2015; 9:296. PMID: 26283926; PMCID: PMC4522550.
        View in: PubMed, PubMed Central
      6. Spitzer N. Neurotransmitter Switching? No Surprise. Neuron. 2015 Jun 03; 86(5):1131-44. PMID: 26050033; PMCID: PMC4458710.
        View in: PubMed, PubMed Central
      7. Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry. 2015 Nov; 20(11):1350-65. PMID: 25385366; PMCID: PMC4427554.
        View in: PubMed, PubMed Central
      8. Guemez-Gamboa A, Xu L, Meng D, Spitzer N. Non-cell-autonomous mechanism of activity-dependent neurotransmitter switching. Neuron. 2014 Jun 04; 82(5):1004-16. PMID: 24908484; PMCID: PMC4072120.
        View in: PubMed, PubMed Central
      9. Yang JM, Zhang J, Chen XJ, Geng HY, Ye M, Spitzer N, Luo JH, Duan SM, Li XM. Development of GABA circuitry of fast-spiking basket interneurons in the medial prefrontal cortex of erbb4-mutant mice. J Neurosci. 2013 Dec 11; 33(50):19724-33. PMID: 24336736.
        View in: PubMed
      10. Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer MA, Greenberg JH, Halgren E, Hämäläinen MS, Helmchen F, Hyman BT, Jasanoff A, Jernigan TL, Judd LL, Kim SG, Kleinfeld D, Kopell NJ, Kutas M, Kwong KK, Larkum ME, Lo EH, Magistretti PJ, Mandeville JB, Masliah E, Mitra PP, Mobley WC, Moskowitz MA, Nimmerjahn A, Reynolds JH, Rosen BR, Salzberg BM, Schaffer CB, Silva GA, So PT, Spitzer N, Tootell RB, Van Essen DC, Vanduffel W, Vinogradov SA, Wald LL, Wang LV, Weber B, Yodh AG. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 2013 Oct 16; 80(2):270-4. PMID: 24139032; PMCID: PMC3864648.
        View in: PubMed, PubMed Central
      11. Spitzer N, Borodinsky LN, Root CM. Imaging and manipulating calcium transients in developing Xenopus spinal neurons. Cold Spring Harb Protoc. 2013 Jul 01; 2013(7):653-64. PMID: 23818661.
        View in: PubMed
      12. Dulcis D, Jamshidi P, Leutgeb S, Spitzer N. Neurotransmitter switching in the adult brain regulates behavior. Science. 2013 Apr 26; 340(6131):449-53. PMID: 23620046.
        View in: PubMed
      13. Plazas PV, Nicol X, Spitzer N. Activity-dependent competition regulates motor neuron axon pathfinding via PlexinA3. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1524-9. PMID: 23302694; PMCID: PMC3557035.
        View in: PubMed, PubMed Central
      14. Dulcis D, Spitzer N. Reserve pool neuron transmitter respecification: Novel neuroplasticity. Dev Neurobiol. 2012 Apr; 72(4):465-74. PMID: 21595049; PMCID: PMC3192250.
        View in: PubMed, PubMed Central
      15. Spitzer N. Activity-dependent neurotransmitter respecification. Nat Rev Neurosci. 2012 Jan 18; 13(2):94-106. PMID: 22251956; PMCID: PMC4352171.
        View in: PubMed, PubMed Central
      16. Demarque M, Spitzer N. Neurotransmitter phenotype plasticity: an unexpected mechanism in the toolbox of network activity homeostasis. Dev Neurobiol. 2012 Jan; 72(1):22-32. PMID: 21557513; PMCID: PMC3209552.
        View in: PubMed, PubMed Central
      17. Rosenberg SS, Spitzer N. Calcium signaling in neuronal development. Cold Spring Harb Perspect Biol. 2011 Oct 01; 3(10):a004259. PMID: 21730044; PMCID: PMC3179332.
        View in: PubMed, PubMed Central
      18. Nicol X, Hong KP, Spitzer N. Spatial and temporal second messenger codes for growth cone turning. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13776-81. PMID: 21795610; PMCID: PMC3158175.
        View in: PubMed, PubMed Central
      19. Hong KP, Spitzer N, Nicol X. Improved molecular toolkit for cAMP studies in live cells. BMC Res Notes. 2011 Jul 20; 4:241. PMID: 21774821; PMCID: PMC3152522.
        View in: PubMed, PubMed Central
      20. Eyler LT, Prom-Wormley E, Fennema-Notestine C, Panizzon MS, Neale MC, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Stevens A, Pacheco J, Perry ME, Schmitt JE, Spitzer N, Seidman LJ, Thermenos HW, Tsuang MT, Dale AM, Kremen WS. Genetic patterns of correlation among subcortical volumes in humans: results from a magnetic resonance imaging twin study. Hum Brain Mapp. 2011 Apr; 32(4):641-53. PMID: 20572207; PMCID: PMC3403693.
        View in: PubMed, PubMed Central
      21. Velázquez-Ulloa NA, Spitzer N, Dulcis D. Contexts for dopamine specification by calcium spike activity in the CNS. J Neurosci. 2011 Jan 05; 31(1):78-88. PMID: 21209192; PMCID: PMC3080040.
        View in: PubMed, PubMed Central
      22. Ben-Ari Y, Spitzer N. Phenotypic checkpoints regulate neuronal development. Trends Neurosci. 2010 Nov; 33(11):485-92. PMID: 20864191; PMCID: PMC2963711.
        View in: PubMed, PubMed Central
      23. Demarque M, Spitzer N. Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior. Neuron. 2010 Jul 29; 67(2):321-34. PMID: 20670838; PMCID: PMC2913149.
        View in: PubMed, PubMed Central
      24. Marek KW, Kurtz LM, Spitzer N. cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification. Nat Neurosci. 2010 Aug; 13(8):944-50. PMID: 20581840; PMCID: PMC2910808.
        View in: PubMed, PubMed Central
      25. Xiao Q, Xu L, Spitzer N. Target-dependent regulation of neurotransmitter specification and embryonic neuronal calcium spike activity. J Neurosci. 2010 Apr 21; 30(16):5792-801. PMID: 20410131; PMCID: PMC2871059.
        View in: PubMed, PubMed Central
      26. Spitzer N. How GABA generates depolarization. J Physiol. 2010 Mar 01; 588(Pt 5):757-8. PMID: 20194137; PMCID: PMC2834934.
        View in: PubMed, PubMed Central
      27. McNerney CD, Chang EJ, Spitzer N. Brain awareness week and beyond: encouraging the next generation. J Undergrad Neurosci Educ. 2009; 8(1):A61-5. PMID: 23493673; PMCID: PMC3592700.
        View in: PubMed, PubMed Central
      28. Chang LW, Spitzer N. Spontaneous calcium spike activity in embryonic spinal neurons is regulated by developmental expression of the Na+, K+-ATPase beta3 subunit. J Neurosci. 2009 Jun 17; 29(24):7877-85. PMID: 19535599; PMCID: PMC3090545.
        View in: PubMed, PubMed Central
      29. Spitzer N. Neuroscience: A bar code for differentiation. Nature. 2009 Apr 16; 458(7240):843-4. PMID: 19370023.
        View in: PubMed
      30. Frantz KJ, McNerney CD, Spitzer N. We've got NERVE: a call to arms for neuroscience education. J Neurosci. 2009 Mar 18; 29(11):3337-9. PMID: 19295139.
        View in: PubMed
      31. Dulcis D, Spitzer N. Illumination controls differentiation of dopamine neurons regulating behaviour. Nature. 2008 Nov 13; 456(7219):195-201. PMID: 19005547; PMCID: PMC2803045.
        View in: PubMed, PubMed Central
      32. Spitzer N. A Rosetta stone for analysis of human membrane protein function. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10641-2. PMID: 18669649; PMCID: PMC2504841.
        View in: PubMed, PubMed Central
      33. Root CM, Velázquez-Ulloa NA, Monsalve GC, Minakova E, Spitzer N. Embryonically expressed GABA and glutamate drive electrical activity regulating neurotransmitter specification. J Neurosci. 2008 Apr 30; 28(18):4777-84. PMID: 18448654; PMCID: PMC3318922.
        View in: PubMed, PubMed Central
      34. Spitzer N, Borodinsky LN. Implications of activity-dependent neurotransmitter-receptor matching. Philos Trans R Soc Lond B Biol Sci. 2008 Apr 12; 363(1495):1393-9. PMID: 18198155; PMCID: PMC2610128.
        View in: PubMed, PubMed Central
      35. Sann SB, Xu L, Nishimune H, Sanes JR, Spitzer N. Neurite outgrowth and in vivo sensory innervation mediated by a Ca(V)2.2-laminin beta 2 stop signal. J Neurosci. 2008 Mar 05; 28(10):2366-74. PMID: 18322083.
        View in: PubMed
      36. Spitzer N. Calcium: first messenger. Nat Neurosci. 2008 Mar; 11(3):243-4. PMID: 18301428.
        View in: PubMed
      37. Borodinsky LN, Spitzer N. Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction. Proc Natl Acad Sci U S A. 2007 Jan 02; 104(1):335-40. PMID: 17190810; PMCID: PMC1749326.
        View in: PubMed, PubMed Central
      38. Spitzer N. Electrical activity in early neuronal development. Nature. 2006 Dec 07; 444(7120):707-12. PMID: 17151658.
        View in: PubMed
      39. Borodinsky LN, Spitzer N. Second messenger pas de deux: the coordinated dance between calcium and cAMP. Sci STKE. 2006 May 23; 2006(336):pe22. PMID: 16720840.
        View in: PubMed
      40. Conklin MW, Lin MS, Spitzer N. Local calcium transients contribute to disappearance of pFAK, focal complex removal and deadhesion of neuronal growth cones and fibroblasts. Dev Biol. 2005 Nov 01; 287(1):201-12. PMID: 16202989.
        View in: PubMed
      41. Bregestovski P, Spitzer N. Calcium in the function of the nervous system: new implications. Cell Calcium. 2005 May; 37(5):371-4. PMID: 15820383.
        View in: PubMed
      42. Spitzer N, Borodinsky LN, Root CM. Homeostatic activity-dependent paradigm for neurotransmitter specification. Cell Calcium. 2005 May; 37(5):417-23. PMID: 15820389.
        View in: PubMed
      43. Ben-Ari Y, Spitzer N. Nature and nurture in brain development. Trends Neurosci. 2004 Jul; 27(7):361. PMID: 15219731.
        View in: PubMed
      44. Spitzer N, Root CM, Borodinsky LN. Orchestrating neuronal differentiation: patterns of Ca2+ spikes specify transmitter choice. Trends Neurosci. 2004 Jul; 27(7):415-21. PMID: 15219741.
        View in: PubMed
      45. Borodinsky LN, Root CM, Cronin JA, Sann SB, Gu X, Spitzer N. Activity-dependent homeostatic specification of transmitter expression in embryonic neurons. Nature. 2004 Jun 03; 429(6991):523-30. PMID: 15175743.
        View in: PubMed
      46. Spitzer N. Coincidence detection enhances appropriate wiring of the nervous system. Proc Natl Acad Sci U S A. 2004 Apr 13; 101(15):5311-2. PMID: 15067118; PMCID: PMC397370.
        View in: PubMed, PubMed Central
      47. Li H, Cook JD, Terry M, Spitzer N, Ferrari MB. Calcium transients regulate patterned actin assembly during myofibrillogenesis. Dev Dyn. 2004 Feb; 229(2):231-42. PMID: 14745949.
        View in: PubMed
      48. Gorbunova YV, Spitzer N. Dynamic interactions of cyclic AMP transients and spontaneous Ca(2+) spikes. Nature. 2002 Jul 04; 418(6893):93-6. PMID: 12097913.
        View in: PubMed
      49. Spitzer N, Kingston PA, Manning TJ, Conklin MW. Outside and in: development of neuronal excitability. Curr Opin Neurobiol. 2002 Jun; 12(3):315-23. PMID: 12049939.
        View in: PubMed
      50. Ming GL, Wong ST, Henley J, Yuan XB, Song HJ, Spitzer N, Poo MM. Adaptation in the chemotactic guidance of nerve growth cones. Nature. 2002 May 23; 417(6887):411-8. PMID: 11986620.
        View in: PubMed
      51. Spitzer N. Activity-dependent neuronal differentiation prior to synapse formation: the functions of calcium transients. J Physiol Paris. 2002 Jan-Mar; 96(1-2):73-80. PMID: 11755785.
        View in: PubMed
      52. Fickbohm DJ, Lynn-Bullock CP, Spitzer N, Caldwell HK, Katz PS. Localization and quantification of 5-hydroxytryptophan and serotonin in the central nervous systems of Tritonia and Aplysia. J Comp Neurol. 2001 Aug 13; 437(1):91-105. PMID: 11477599.
        View in: PubMed
      53. Gomez TM, Robles E, Poo M, Spitzer N. Filopodial calcium transients promote substrate-dependent growth cone turning. Science. 2001 Mar 09; 291(5510):1983-7. PMID: 11239161.
        View in: PubMed
      54. Spitzer N, Vincent A, Lautermilch NJ. Differentiation of electrical excitability in motoneurons. Brain Res Bull. 2000 Nov 15; 53(5):547-52. PMID: 11165790.
        View in: PubMed
      55. Watt SD, Gu X, Smith RD, Spitzer N. Specific frequencies of spontaneous Ca2+ transients upregulate GAD 67 transcripts in embryonic spinal neurons. Mol Cell Neurosci. 2000 Oct; 16(4):376-87. PMID: 11085875.
        View in: PubMed
      56. Spitzer N, Lautermilch NJ, Smith RD, Gomez TM. Coding of neuronal differentiation by calcium transients. Bioessays. 2000 Sep; 22(9):811-7. PMID: 10944583.
        View in: PubMed
      57. Vincent A, Lautermilch NJ, Spitzer N. Antisense suppression of potassium channel expression demonstrates its role in maturation of the action potential. J Neurosci. 2000 Aug 15; 20(16):6087-94. PMID: 10934258.
        View in: PubMed
      58. Gomez TM, Spitzer N. Regulation of growth cone behavior by calcium: new dynamics to earlier perspectives. J Neurobiol. 2000 Aug; 44(2):174-83. PMID: 10934320.
        View in: PubMed
      59. Gurantz D, Lautermilch NJ, Watt SD, Spitzer N. Sustained upregulation in embryonic spinal neurons of a Kv3.1 potassium channel gene encoding a delayed rectifier current. J Neurobiol. 2000 Feb 15; 42(3):347-56. PMID: 10645974.
        View in: PubMed
      60. Lautermilch NJ, Spitzer N. Regulation of calcineurin by growth cone calcium waves controls neurite extension. J Neurosci. 2000 Jan 01; 20(1):315-25. PMID: 10627609.
        View in: PubMed
      61. Rohrbough J, Spitzer N. Ca(2+)-permeable AMPA receptors and spontaneous presynaptic transmitter release at developing excitatory spinal synapses. J Neurosci. 1999 Oct 01; 19(19):8528-41. PMID: 10493753.
        View in: PubMed
      62. Ferrari MB, Spitzer N. Calcium signaling in the developing Xenopus myotome. Dev Biol. 1999 Sep 15; 213(2):269-82. PMID: 10479447.
        View in: PubMed
      63. Spitzer N. New dimensions of neuronal plasticity. Nat Neurosci. 1999 Jun; 2(6):489-91. PMID: 10448206.
        View in: PubMed
      64. Gomez TM, Spitzer N. In vivo regulation of axon extension and pathfinding by growth-cone calcium transients. Nature. 1999 Jan 28; 397(6717):350-5. PMID: 9950427.
        View in: PubMed
      65. Olson EC, Schinder AF, Dantzker JL, Marcus EA, Spitzer N, Harris WA. Properties of ectopic neurons induced by Xenopus neurogenin1 misexpression. Mol Cell Neurosci. 1998 Nov; 12(4-5):281-99. PMID: 9828092.
        View in: PubMed
      66. Spitzer N, Ribera AB. Development of electrical excitability in embryonic neurons: mechanisms and roles. J Neurobiol. 1998 Oct; 37(1):190-7. PMID: 9777741.
        View in: PubMed
      67. Ribera AB, Spitzer N. Development of electrical excitability: mechanisms and roles. J Neurobiol. 1998 Oct; 37(1):1-2. PMID: 9777728.
        View in: PubMed
      68. Jessen-Eller K, Steele M, Reinisch C, Spitzer N. Blockade of ryanodine receptors stimulates neurite outgrowth in embryos of Spisula solidissima. Biol Bull. 1998 Oct; 195(2):206-7. PMID: 9818372.
        View in: PubMed
      69. Ferrari MB, Ribbeck K, Hagler DJ, Spitzer N. A calcium signaling cascade essential for myosin thick filament assembly in Xenopus myocytes. J Cell Biol. 1998 Jun 15; 141(6):1349-56. PMID: 9628891; PMCID: PMC2132793.
        View in: PubMed, PubMed Central
      70. Gleason EL, Spitzer N. AMPA and NMDA receptors expressed by differentiating Xenopus spinal neurons. J Neurophysiol. 1998 Jun; 79(6):2986-98. PMID: 9636102.
        View in: PubMed
      71. Spitzer N, Sejnowski TJ. Biological information processing: bits of progress. Science. 1997 Aug 22; 277(5329):1060-1. PMID: 9289851.
        View in: PubMed
      72. Spitzer N, Gu X. Purposeful patterns of spontaneous calcium transients in embryonic spinal neurons. Semin Cell Dev Biol. 1997 Feb; 8(1):13-9. PMID: 15001100.
        View in: PubMed
      73. Gu X, Spitzer N. Breaking the code: regulation of neuronal differentiation by spontaneous calcium transients. Dev Neurosci. 1997; 19(1):33-41. PMID: 9078431.
        View in: PubMed
      74. Schinder AF, Olson EC, Spitzer N, Montal M. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J Neurosci. 1996 Oct 01; 16(19):6125-33. PMID: 8815895.
        View in: PubMed
      75. Ferrari MB, Rohrbough J, Spitzer N. Spontaneous calcium transients regulate myofibrillogenesis in embryonic Xenopus myocytes. Dev Biol. 1996 Sep 15; 178(2):484-97. PMID: 8812144.
        View in: PubMed
      76. Gurantz D, Ribera AB, Spitzer N. Temporal regulation of Shaker- and Shab-like potassium channel gene expression in single embryonic spinal neurons during K+ current development. J Neurosci. 1996 May 15; 16(10):3287-95. PMID: 8627366.
        View in: PubMed
      77. Rohrbough J, Spitzer N. Regulation of intracellular Cl- levels by Na(+)-dependent Cl- cotransport distinguishes depolarizing from hyperpolarizing GABAA receptor-mediated responses in spinal neurons. J Neurosci. 1996 Jan; 16(1):82-91. PMID: 8613812.
        View in: PubMed
      78. Gu X, Spitzer N. Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transients. Nature. 1995 Jun 29; 375(6534):784-7. PMID: 7596410.
        View in: PubMed
      79. Ernsberger U, Spitzer N. Convertible modes of inactivation of potassium channels in Xenopus myocytes differentiating in vitro. J Physiol. 1995 Apr 15; 484 ( Pt 2):313-29. PMID: 7602528; PMCID: PMC1157896.
        View in: PubMed, PubMed Central
      80. Spitzer N, Olson E, Gu X. Spontaneous calcium transients regulate neuronal plasticity in developing neurons. J Neurobiol. 1995 Mar; 26(3):316-24. PMID: 7775965.
        View in: PubMed
      81. Spitzer N. Spontaneous activity: functions of calcium transients in neuronal differentiation. Perspect Dev Neurobiol. 1995; 2(4):379-86. PMID: 7757407.
        View in: PubMed
      82. Gu X, Olson EC, Spitzer N. Spontaneous neuronal calcium spikes and waves during early differentiation. J Neurosci. 1994 Nov; 14(11 Pt 1):6325-35. PMID: 7965039.
        View in: PubMed
      83. Spitzer N. Spontaneous Ca2+ spikes and waves in embryonic neurons: signaling systems for differentiation. Trends Neurosci. 1994 Mar; 17(3):115-8. PMID: 7515527.
        View in: PubMed
      84. Spitzer N, Gu X, Olson E. Action potentials, calcium transients and the control of differentiation of excitable cells. Curr Opin Neurobiol. 1994 Feb; 4(1):70-7. PMID: 7513567.
        View in: PubMed
      85. Spitzer N. Development of voltage-dependent and ligand-gated channels in excitable membranes. Prog Brain Res. 1994; 102:169-79. PMID: 7528434.
        View in: PubMed
      86. Spitzer N. Calcium and gene expression. Prog Brain Res. 1994; 103:123-6. PMID: 7886200.
        View in: PubMed
      87. Spitzer N, Debaca RC, Allen KA, Holliday J. Calcium dependence of differentiation of GABA immunoreactivity in spinal neurons. J Comp Neurol. 1993 Nov 01; 337(1):168-75. PMID: 7506271.
        View in: PubMed
      88. Gu X, Spitzer N. Low-threshold Ca2+ current and its role in spontaneous elevations of intracellular Ca2+ in developing Xenopus neurons. J Neurosci. 1993 Nov; 13(11):4936-48. PMID: 8229206.
        View in: PubMed
      89. Desarmenien MG, Clendening B, Spitzer N. In vivo development of voltage-dependent ionic currents in embryonic Xenopus spinal neurons. J Neurosci. 1993 Jun; 13(6):2575-81. PMID: 8501523.
        View in: PubMed
      90. Holliday J, Spitzer N. Calcium regulates neuronal differentiation both directly and via co-cultured myocytes. J Neurobiol. 1993 Apr; 24(4):506-14. PMID: 8515253.
        View in: PubMed
      91. Lockery SR, Spitzer N. Reconstruction of action potential development from whole-cell currents of differentiating spinal neurons. J Neurosci. 1992 Jun; 12(6):2268-87. PMID: 1607940.
        View in: PubMed
      92. Ribera AB, Spitzer N. Developmental regulation of potassium channels and the impact on neuronal differentiation. Ion Channels. 1992; 3:1-38. PMID: 1421060.
        View in: PubMed
      93. Desarmenien MG, Spitzer N. Role of calcium and protein kinase C in development of the delayed rectifier potassium current in Xenopus spinal neurons. Neuron. 1991 Nov; 7(5):797-805. PMID: 1742026.
        View in: PubMed
      94. Holliday J, Adams RJ, Sejnowski TJ, Spitzer N. Calcium-induced release of calcium regulates differentiation of cultured spinal neurons. Neuron. 1991 Nov; 7(5):787-96. PMID: 1742025.
        View in: PubMed
      95. Spitzer N. A developmental handshake: neuronal control of ionic currents and their control of neuronal differentiation. J Neurobiol. 1991 Oct; 22(7):659-73. PMID: 1722506.
        View in: PubMed
      96. Ribera AB, Spitzer N. Differentiation of delayed rectifier potassium current in embryonic amphibian myocytes. Dev Biol. 1991 Mar; 144(1):119-28. PMID: 1995391.
        View in: PubMed
      97. Holliday J, Spitzer N. Spontaneous calcium influx and its roles in differentiation of spinal neurons in culture. Dev Biol. 1990 Sep; 141(1):13-23. PMID: 2167857.
        View in: PubMed
      98. Ribera AB, Spitzer N. Differentiation of IKA in amphibian spinal neurons. J Neurosci. 1990 Jun; 10(6):1886-91. PMID: 2355255.
        View in: PubMed
      99. Ribera AB, Spitzer N. A critical period of transcription required for differentiation of the action potential of spinal neurons. Neuron. 1989 Jan; 2(1):1055-62. PMID: 2483107.
        View in: PubMed
      100. Harris GL, Henderson LP, Spitzer N. Changes in densities and kinetics of delayed rectifier potassium channels during neuronal differentiation. Neuron. 1988 Oct; 1(8):739-50. PMID: 3272186.
        View in: PubMed
      101. O'Dowd DK, Ribera AB, Spitzer N. Development of voltage-dependent calcium, sodium, and potassium currents in Xenopus spinal neurons. J Neurosci. 1988 Mar; 8(3):792-805. PMID: 3346722.
        View in: PubMed
      102. Ribera AB, Spitzer N. Both barium and calcium activate neuronal potassium currents. Proc Natl Acad Sci U S A. 1987 Sep; 84(18):6577-81. PMID: 2442762; PMCID: PMC299122.
        View in: PubMed, PubMed Central
      103. Henderson LP, Spitzer N. Autonomous early differentiation of neurons and muscle cells in single cell cultures. Dev Biol. 1986 Feb; 113(2):381-7. PMID: 2868950.
        View in: PubMed
      104. Easter SS, Purves D, Rakic P, Spitzer N. The changing view of neural specificity. Science. 1985 Nov 01; 230(4725):507-11. PMID: 4048944.
        View in: PubMed
      105. Henderson LP, Smith MA, Spitzer N. The absence of calcium blocks impulse-evoked release of acetylcholine but not de novo formation of functional neuromuscular synaptic contacts in culture. J Neurosci. 1984 Dec; 4(12):3140-50. PMID: 6094749.
        View in: PubMed
      106. Spitzer N. On the basis of delayed depolarization and its role in repetitive firing of Rohon-Beard neurones in Xenopus tadpoles. J Physiol. 1984 Dec; 357:51-65. PMID: 6512703; PMCID: PMC1193246.
        View in: PubMed, PubMed Central
      107. Bixby JL, Spitzer N. Early differentiation of vertebrate spinal neurons in the absence of voltage-dependent Ca2+ and Na+ influx. Dev Biol. 1984 Nov; 106(1):89-96. PMID: 6092180.
        View in: PubMed
      108. Bixby JL, Spitzer N. The appearance and development of neurotransmitter sensitivity in Xenopus embryonic spinal neurones in vitro. J Physiol. 1984 Aug; 353:143-55. PMID: 6148408; PMCID: PMC1193299.
        View in: PubMed, PubMed Central
      109. Bixby JL, Spitzer N. Enkephalin reduces calcium action potentials in Rohon-Beard neurons in vivo. J Neurosci. 1983 May; 3(5):1014-8. PMID: 6842279.
        View in: PubMed
      110. Bixby JL, Spitzer N. Enkephalin reduces quantal content at the frog neuromuscular junction. Nature. 1983 Feb 03; 301(5899):431-2. PMID: 6823319.
        View in: PubMed
      111. Bixby JL, Spitzer N. The appearance and development of chemosensitivity in Rohon-Beard neurones of the Xenopus spinal cord. J Physiol. 1982 Sep; 330:513-36. PMID: 6294289; PMCID: PMC1225313.
        View in: PubMed, PubMed Central
      112. Spitzer N. Voltage- and stage-dependent uncoupling of Rohon-Beard neurones during embryonic development of Xenopus tadpoles. J Physiol. 1982 Sep; 330:145-62. PMID: 7175739; PMCID: PMC1225291.
        View in: PubMed, PubMed Central
      113. Bate M, Goodman CS, Spitzer N. Embryonic development of identified neurons: segment-specific differences in the H cell homologues. J Neurosci. 1981 Jan; 1(1):103-6. PMID: 7346554.
        View in: PubMed
      114. Goodman CS, Bate M, Spitzer N. Embryonic development of identified neurons: origin and transformation of the H cell. J Neurosci. 1981 Jan; 1(1):94-102. PMID: 7346562.
        View in: PubMed
      115. Goodman CS, Spitzer N. The mature electrical properties of identified neurones in grasshopper embryos. J Physiol. 1981; 313:369-84. PMID: 7277226; PMCID: PMC1274457.
        View in: PubMed, PubMed Central
      116. Goodman CS, Spitzer N. The development of electrical properties of identified neurones in grasshopper embryos. J Physiol. 1981; 313:385-403. PMID: 7277228; PMCID: PMC1274458.
        View in: PubMed, PubMed Central
      117. Goodman CS, Pearson KG, Spitzer N. Electrical excitability: a spectrum of properties in the progeny of a single embryonic neuroblast. Proc Natl Acad Sci U S A. 1980 Mar; 77(3):1676-80. PMID: 6246499; PMCID: PMC348560.
        View in: PubMed, PubMed Central
      118. Darszon A, Vandenberg CA, Schönfeld M, Ellisman MH, Spitzer N, Montal M. Reassembly of protein-lipid complexes into large bilayer vesicles: perspectives for membrane reconstitution. Proc Natl Acad Sci U S A. 1980 Jan; 77(1):239-43. PMID: 6244547; PMCID: PMC348244.
        View in: PubMed, PubMed Central
      119. Goodman CS, Spitzer N. Embryonic development of identified neurones: differentiation from neuroblast to neurone. Nature. 1979 Jul 19; 280(5719):208-14. PMID: 450137.
        View in: PubMed
      120. Goodman CS, O'Shea M, McCaman R, Spitzer N. Embryonic development of identified neurons: temporal pattern of morphological and biochemical differentiation. Science. 1979 Jun 15; 204(4398):1219-22. PMID: 36661.
        View in: PubMed
      121. Lamborghini JE, Revenaugh M, Spitzer N. Ultrastructural development of Rohon-Beard neurons: loss of intramitochondrial granules parallels loss of calcium action potentials. J Comp Neurol. 1979 Feb 15; 183(4):741-52. PMID: 762270.
        View in: PubMed
      122. Spitzer N. Low pH selectively blocks calcium action potentials in amphibian neurons developing in culture. Brain Res. 1979 Feb 09; 161(3):555-9. PMID: 33747.
        View in: PubMed
      123. Spitzer N. Ion channels in development. Annu Rev Neurosci. 1979; 2:363-97. PMID: 395884.
        View in: PubMed
      124. Baccaglini PI, Spitzer N. Developmental changes in the inward current of the action potential of Rohon-Beard neurones. J Physiol. 1977 Sep; 271(1):93-117. PMID: 915836; PMCID: PMC1353609.
        View in: PubMed, PubMed Central
      125. Spitzer N, Baccaglini PI. Development of the action potential in embryo amphibian neurons in vivo. Brain Res. 1976 May 14; 107(3):610-6. PMID: 1268744.
        View in: PubMed
      126. Spitzer N, Lamborghini JE. The development of the action potential mechanism of amphibian neurons isolated in culture. Proc Natl Acad Sci U S A. 1976 May; 73(5):1641-5. PMID: 1064036; PMCID: PMC430355.
        View in: PubMed, PubMed Central
      127. Spitzer N. The ionic basis of the resting potential and a slow depolarizing response in Rohon-Beard neurones of Xenopus tadpoles. J Physiol. 1976 Feb; 255(1):105-35. PMID: 1255512; PMCID: PMC1309237.
        View in: PubMed, PubMed Central
      128. Doore BJ, Bashor MM, Spitzer N, Mawe RC, Saier MH. Regulation of adenosine 3' :5'-monophosphate efflux from rat glioma cells in culture*. J Biol Chem. 1975 Jun 10; 250(11):4371-2. PMID: 165200.
        View in: PubMed
      129. Miledi R, Spitzer N. Absence of action potentials in frog slow muscle fibres paralysed by botulinum toxin. J Physiol. 1974 Aug; 241(1):183-99. PMID: 4371279; PMCID: PMC1331080.
        View in: PubMed, PubMed Central
      130. Holman ME, Spitzer N. Action of botulinum toxin on transmission from sympathetic nerves to the vas deferens. Br J Pharmacol. 1973 Feb; 47(2):431-3. PMID: 4352870; PMCID: PMC1776555.
        View in: PubMed, PubMed Central
      131. McMahan UJ, Spitzer N. Viewing neuromuscular junctions in live, unstained skeletal muscle. J Physiol. 1971 Jul; 216(1):35P-37P. PMID: 5558366.
        View in: PubMed
      132. Spitzer N. Low resistance connections between cells in the developing anther of the lily. J Cell Biol. 1970 Jun; 45(3):565-75. PMID: 4918215; PMCID: PMC2107936.
        View in: PubMed, PubMed Central
      Nicholas's Networks
      Concepts
      Derived automatically from this person's publications.
      See all (456) concept(s)
      _
      Co-Authors
      People in Profiles who have published with this person.
      See all (28) people
      _
      Similar People
      People who share similar concepts with this person.
      See all (60) people
      _
      Same Department
      Search Department
      Physical Neighbors
      People whose addresses are nearby this person.
      _