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    Neil Grimsey

    TitleAssistant Project Scientist
    SchoolUniversity of California, San Diego
    DepartmentPharmacology
    Address9500 Gilman Drive #0636
    CA La Jolla 92093
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Dores MR, Grimsey N, Mendez F, Trejo J. ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif. PLoS One. 2016; 11(6):e0157587. PMID: 27301021; PMCID: PMC4907476.
      2. Grimsey N, Trejo J. Integration of endothelial protease-activated receptor-1 inflammatory signaling by ubiquitin. Curr Opin Hematol. 2016 May; 23(3):274-9. PMID: 26845544; PMCID: PMC4978167 [Available on 05/01/17].
      3. Grimsey N, Coronel LJ, Cordova IC, Trejo J. Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins. J Biol Chem. 2016 Jan 29; 291(5):2223-36. PMID: 26635365; PMCID: PMC4732206 [Available on 01/29/17].
      4. Grimsey N, Aguilar B, Smith TH, Le P, Soohoo AL, Puthenveedu MA, Nizet V, Trejo J. Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. J Cell Biol. 2015 Sep 28; 210(7):1117-31. PMID: 26391660; PMCID: PMC4586747.
      5. Kawamura T, Stephens B, Qin L, Yin X, Dores MR, Smith TH, Grimsey N, Abagyan R, Trejo J, Kufareva I, Fuster MM, Salanga CL, Handel TM. A general method for site specific fluorescent labeling of recombinant chemokines. PLoS One. 2014; 9(1):e81454. PMID: 24489642; PMCID: PMC3904831.
      6. Grimsey N, Lin H, Trejo J. Endosomal signaling by protease-activated receptors. Methods Enzymol. 2014; 535:389-401. PMID: 24377935; PMCID: PMC4085098.
      7. Sembongi H, Miranda M, Han GS, Fakas S, Grimsey N, Vendrell J, Carman GM, Siniossoglou S. Distinct roles of the phosphatidate phosphatases lipin 1 and 2 during adipogenesis and lipid droplet biogenesis in 3T3-L1 cells. J Biol Chem. 2013 Nov 29; 288(48):34502-13. PMID: 24133206; PMCID: PMC3843065.
      8. Chen B, Dores MR, Grimsey N, Canto I, Barker BL, Trejo J. Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals. J Biol Chem. 2011 Nov 25; 286(47):40760-70. PMID: 21965661; PMCID: PMC3220480.
      9. Renna M, Schaffner C, Brown K, Shang S, Tamayo MH, Hegyi K, Grimsey N, Cusens D, Coulter S, Cooper J, Bowden AR, Newton SM, Kampmann B, Helm J, Jones A, Haworth CS, Basaraba RJ, DeGroote MA, Ordway DJ, Rubinsztein DC, Floto RA. Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection. J Clin Invest. 2011 Sep; 121(9):3554-63. PMID: 21804191; PMCID: PMC3163956.
      10. Grimsey N, Soto AG, Trejo J. Regulation of protease-activated receptor signaling by post-translational modifications. IUBMB Life. 2011 Jun; 63(6):403-11. PMID: 21438117; PMCID: PMC3121918.
      11. Grimsey N, Han GS, O'Hara L, Rochford JJ, Carman GM, Siniossoglou S. Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2. J Biol Chem. 2008 Oct 24; 283(43):29166-74. PMID: 18694939; PMCID: PMC2570901.
      12. Fawcett KA, Grimsey N, Loos RJ, Wheeler E, Daly A, Soos M, Semple R, Syddall H, Cooper C, Siniossoglou S, O'Rahilly S, Wareham NJ, Barroso I. Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations. Diabetes. 2008 Sep; 57(9):2527-33. PMID: 18591397; PMCID: PMC2518506.
      13. Payne VA, Grimsey N, Tuthill A, Virtue S, Gray SL, Dalla Nora E, Semple RK, O'Rahilly S, Rochford JJ. The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation. Diabetes. 2008 Aug; 57(8):2055-60. PMID: 18458148; PMCID: PMC2494687.
      14. Frigerio G, Grimsey N, Dale M, Majoul I, Duden R. Two human ARFGAPs associated with COP-I-coated vesicles. Traffic. 2007 Nov; 8(11):1644-55. PMID: 17760859; PMCID: PMC2171037.
      15. O'Hara L, Han GS, Peak-Chew S, Grimsey N, Carman GM, Siniossoglou S. Control of phospholipid synthesis by phosphorylation of the yeast lipin Pah1p/Smp2p Mg2+-dependent phosphatidate phosphatase. J Biol Chem. 2006 Nov 10; 281(45):34537-48. PMID: 16968695; PMCID: PMC1769310.
      16. Santos-Rosa H, Leung J, Grimsey N, Peak-Chew S, Siniossoglou S. The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth. EMBO J. 2005 Jun 01; 24(11):1931-41. PMID: 15889145; PMCID: PMC1142606.
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