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    Morgan Desantis

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentCellular and Molecular Medicine
    Address9500 Gilman Drive #0694
    CA La Jolla 92093
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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Cianfrocco MA, DeSantis ME, Leschziner AE, Reck-Peterson SL. Mechanism and Regulation of Cytoplasmic Dynein. Annu Rev Cell Dev Biol. 2015 Nov 13; 31:83-108. PMID: 26436706.
        View in: PubMed
      2. Sweeny EA, Jackrel ME, Go MS, Sochor MA, Razzo BM, DeSantis ME, Gupta K, Shorter J. The hsp104 N-terminal domain enables disaggregase plasticity and potentiation. Mol Cell. 2015 Mar 5; 57(5):836-49. PMID: 25620563.
        View in: PubMed
      3. Jackrel ME, DeSantis ME, Martinez BA, Castellano LM, Stewart RM, Caldwell KA, Caldwell GA, Shorter J. Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events. Cell. 2014 Jan 16; 156(1-2):170-82. PMID: 24439375.
        View in: PubMed
      4. Desantis M, Sweeny EA, Snead D, Leung EH, Go MS, Gupta K, Wendler P, Shorter J. Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation. J Biol Chem. 2014 Jan 10; 289(2):848-67. PMID: 24280225.
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      5. Coelho M, Dereli A, Haese A, Kühn S, Malinovska L, DeSantis ME, Shorter J, Alberti S, Gross T, Tolic-Nørrelykke IM. Fission yeast does not age under favorable conditions, but does so after stress. Curr Biol. 2013 Oct 7; 23(19):1844-52. PMID: 24035542.
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      6. DeSantis ME, Shorter J. Hsp104 drives "protein-only" positive selection of Sup35 prion strains encoding strong [PSI(+)]. Chem Biol. 2012 Nov 21; 19(11):1400-10. PMID: 23177195.
        View in: PubMed
      7. DeSantis ME, Leung EH, Sweeny EA, Jackrel ME, Cushman-Nick M, Neuhaus-Follini A, Vashist S, Sochor MA, Knight MN, Shorter J. Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients. Cell. 2012 Nov 9; 151(4):778-93. PMID: 23141537.
        View in: PubMed
      8. Acchione M, Lee YC, DeSantis ME, Lipschultz CA, Wlodawer A, Li M, Shanmuganathan A, Walter RL, Smith-Gill S, Barchi JJ. Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics. Biochemistry. 2012 Jul 31; 51(30):6017-27. PMID: 22769726.
        View in: PubMed
      9. Sweeny EA, DeSantis ME, Shorter J. Purification of hsp104, a protein disaggregase. J Vis Exp. 2011; (55). PMID: 21989490.
        View in: PubMed
      10. Desantis M, Shorter J. The elusive middle domain of Hsp104 and ClpB: location and function. Biochim Biophys Acta. 2012 Jan; 1823(1):29-39. PMID: 21843558.
        View in: PubMed
      11. DeSantis ME, Dersh D. Preventing Parkinson's pathology. Dis Model Mech. 2010 Jul-Aug; 3(7-8):399-400. PMID: 20483997.
        View in: PubMed
      12. Acchione M, Lipschultz CA, DeSantis ME, Shanmuganathan A, Li M, Wlodawer A, Tarasov S, Smith-Gill SJ. Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies. Mol Immunol. 2009 Dec; 47(2-3):457-64. PMID: 19781789.
        View in: PubMed
      13. Mohan S, Kourentzi K, Schick KA, Uehara C, Lipschultz CA, Acchione M, Desantis M, Smith-Gill SJ, Willson RC. Association energetics of cross-reactive and specific antibodies. Biochemistry. 2009 Feb 17; 48(6):1390-8. PMID: 19166328.
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      14. Lohmeyer M, Harrison PM, Kannan S, DeSantis M, O'Reilly NJ, Sternberg MJ, Salomon DS, Gullick WJ. Chemical synthesis, structural modeling, and biological activity of the epidermal growth factor-like domain of human cripto. Biochemistry. 1997 Apr 1; 36(13):3837-45. PMID: 9092813.
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