Michael Grundman

Title(s)Adjunct Professor, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Value-Generating Exploratory Trials in Neurodegenerative Dementias. Neurology. 2021 05 18; 96(20):944-954. Friedman LG, McKeehan N, Hara Y, Cummings JL, Matthews DC, Zhu J, Mohs RC, Wang D, Hendrix SB, Quintana M, Schneider LS, Grundman M, Dickson SP, Feldman HH, Jaeger J, Finger EC, Ryan JM, Niehoff D, Dickinson SL, Markowitz JT, Owen M, Travaglia A, Fillit HM. PMID: 33674360; PMCID: PMC8205472.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    2. Editorial: Tau Based Therapeutics: Alternative Approaches in the War on Alzheimer's Disease. J Prev Alzheimers Dis. 2019; 6(3):151-152. Grundman M. PMID: 31062822.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials. Neurology. 2015 Aug 25; 85(8):692-700. Liu E, Schmidt ME, Margolin R, Sperling R, Koeppe R, Mason NS, Klunk WE, Mathis CA, Salloway S, Fox NC, Hill DL, Les AS, Collins P, Gregg KM, Di J, Lu Y, Tudor IC, Wyman BT, Booth K, Broome S, Yuen E, Grundman M, Brashear HR, Bapineuzumab 301 and 302 Clinical Trial Investigators. PMID: 26208959; PMCID: PMC4553028.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCTClinical Trials
    4. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med. 2014 Jan 23; 370(4):322-33. Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR, Bapineuzumab 301 and 302 Clinical Trial Investigators. PMID: 24450891; PMCID: PMC4159618.
      View in: PubMed   Mentions: 782     Fields:    Translation:HumansCellsCTClinical Trials
    5. Potential impact of amyloid imaging on diagnosis and intended management in patients with progressive cognitive decline. Alzheimer Dis Assoc Disord. 2013 Jan-Mar; 27(1):4-15. Grundman M, Pontecorvo MJ, Salloway SP, Doraiswamy PM, Fleisher AS, Sadowsky CH, Nair AK, Siderowf A, Lu M, Arora AK, Agbulos A, Flitter ML, Krautkramer MJ, Sarsour K, Skovronsky DM, Mintun MA, 45-A17 Study Group. PMID: 23203162.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCTClinical Trials
    6. Report of the task force on designing clinical trials in early (predementia) AD. Neurology. 2011 Jan 18; 76(3):280-6. Aisen PS, Andrieu S, Sampaio C, Carrillo M, Khachaturian ZS, Dubois B, Feldman HH, Petersen RC, Siemers E, Doody RS, Hendrix SB, Grundman M, Schneider LS, Schindler RJ, Salmon E, Potter WZ, Thomas RG, Salmon D, Donohue M, Bednar MM, Touchon J, Vellas B. PMID: 21178097; PMCID: PMC3034393.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    7. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Arch Neurol. 2005 Jun; 62(6):953-7. Fleisher A, Grundman M, Jack CR, Petersen RC, Taylor C, Kim HT, Schiller DH, Bagwell V, Sencakova D, Weiner MF, DeCarli C, DeKosky ST, van Dyck CH, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 15956166.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCTClinical Trials
    8. Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol. 2004 Jan; 61(1):59-66. Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR, Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, Mintzer J, Zamrini EY, Cahn-Weiner D, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 14732621.
      View in: PubMed   Mentions: 315     Fields:    Translation:HumansCTClinical Trials
    9. Idebenone treatment fails to slow cognitive decline in Alzheimer's disease. Neurology. 2003 Dec 09; 61(11):1498-502. Thal LJ, Grundman M, Berg J, Ernstrom K, Margolin R, Pfeiffer E, Weiner MF, Zamrini E, Thomas RG. PMID: 14663031.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCTClinical Trials
    10. A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients. Life Sci. 2003 Jun 20; 73(5):539-53. Grundman M, Capparelli E, Kim HT, Morris JC, Farlow M, Rubin EH, Heidebrink J, Hake A, Ho G, Schultz AN, Schafer K, Houston W, Thomas R, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 12770610.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    11. Estrogen levels do not correlate with improvement in cognition. Arch Neurol. 2003 Feb; 60(2):209-12. Thal LJ, Thomas RG, Mulnard R, Sano M, Grundman M, Schneider L. PMID: 12580705.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    12. Hippocampal volume is associated with memory but not monmemory cognitive performance in patients with mild cognitive impairment. J Mol Neurosci. 2003; 20(3):241-8. Grundman M, Jack CR, Petersen RC, Kim HT, Taylor C, Datvian M, Weiner MF, DeCarli C, DeKosky ST, van Dyck C, Darvesh S, Yaffe K, Kaye J, Ferris SH, Thomas RG, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 14501003.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    13. Brain MRI hippocampal volume and prediction of clinical status in a mild cognitive impairment trial. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):23-7. Grundman M, Sencakova D, Jack CR, Petersen RC, Kim HT, Schultz A, Weiner MF, DeCarli C, DeKosky ST, van Dyck C, Thomas RG, Thal LJ, Alzheimer's Disease Cooperative Study. PMID: 12212787.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    14. Antioxidant strategies for Alzheimer's disease. Proc Nutr Soc. 2002 May; 61(2):191-202. Grundman M, Grundman M, Delaney P. PMID: 12133201.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    15. Treatment of Alzheimer's disease: rationale and strategies. Neurol Clin. 2000 Nov; 18(4):807-28. Grundman M, Thal LJ. PMID: 11072262.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    16. Vitamin E and Alzheimer disease: the basis for additional clinical trials. Am J Clin Nutr. 2000 Feb; 71(2):630S-636S. Grundman M. PMID: 10681271.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    17. Prevalence of symptoms on the CERAD behavior rating scale for dementia in normal elderly subjects and Alzheimer's disease patients. J Neuropsychiatry Clin Neurosci. 2000; 12(4):472-9. Tractenberg RE, Patterson M, Weiner MF, Teri L, Grundman M, Thomas RG, Thal LJ. PMID: 11083164.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Mini-Mental State Examination and Mattis Dementia Rating Scale performance differs in Hispanic and non-Hispanic Alzheimer's disease patients. J Int Neuropsychol Soc. 1999 May; 5(4):301-7. Hohl U, Grundman M, Salmon DP, Thomas RG, Thal LJ. PMID: 10349293.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. Perspectives in clinical Alzheimer's disease research and the development of antidementia drugs. J Neural Transm Suppl. 1998; 53:255-75. Grundman M, Corey-Bloom J, Thal LJ. PMID: 9700663.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. The impact of apolipoprotein E4 on cause of death in Alzheimer's disease. Neurology. 1997 Jul; 49(1):76-81. Olichney JM, Sabbagh MN, Hofstetter CR, Galasko D, Grundman M, Katzman R, Thal LJ. PMID: 9222173.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord. 1997; 11 Suppl 2:S33-9. Galasko D, Bennett D, Sano M, Ernesto C, Thomas R, Grundman M, Ferris S. PMID: 9236950.
      View in: PubMed   Mentions: 433     Fields:    Translation:HumansCTClinical Trials
    22. Low body weight in Alzheimer's disease is associated with mesial temporal cortex atrophy. Neurology. 1996 Jun; 46(6):1585-91. Grundman M, Corey-Bloom J, Jernigan T, Archibald S, Thal LJ. PMID: 8649553.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    23. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension. Arch Neurol. 1995 Jul; 52(7):702-8. Olichney JM, Hansen LA, Hofstetter CR, Grundman M, Katzman R, Thal LJ. PMID: 7619027.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    24. Dementia: characteristics of a referral population and factors associated with progression. Neurology. 1988 Jul; 38(7):1083-90. Thal LJ, Grundman M, Klauber MR. PMID: 3386827.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
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