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    Matthias Von Herrath

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0673
    CA La Jolla 92093
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      Collapse Research 
      Collapse Research Activities and Funding
      Integrated Functional Histopathology of the Diabetic Human Pancreas
      NIH/NIAID R01AI134971Dec 7, 2017 - Nov 30, 2022
      Role: Principal Investigator
      Specificity, Phenotype and Function of Pancreatic CD8 T Cells in Human Type 1 Diabetes
      NIH/NIAID R01AI092453May 2, 2011 - Nov 30, 2021
      Role: Principal Investigator
      How IL-10R blockade can resolve persistent viral infections
      NIH/NIAID R01AI068818Sep 1, 2007 - Aug 31, 2012
      Role: Principal Investigator
      Animal Models in Type 1 Diabetes and Multiple Sclerosis
      NIH/NIDDK R13DK076554Sep 30, 2006 - Aug 31, 2007
      Role: Principal Investigator
      Assessment of cytokines in human islets from patients with diabetes
      NIH/NIAID U01AI102370Sep 20, 2006 - Jun 30, 2017
      Role: Principal Investigator
      Achieving Therapeutic Antigent-Specific Tolerance in Type 1 Diabetes
      NIH/NIDDK U01DK078013Sep 20, 2006 - Jun 30, 2012
      Role: Principal Investigator
      FASEB Summer Conference on 'Autoimmunity'
      NIH/NIAID R13AI065123Jun 1, 2005 - May 31, 2010
      Role: Principal Investigator
      Viruses and Autoimmunity POI
      NIH/NIAID P01AI058105Jul 1, 2004 - Jun 30, 2010
      Role: Principal Investigator
      IMMUNE TOLERANCE INDUCTION BY APOPTOTIC BODIES
      NIH/NIAID R21AI059850May 1, 2004 - Apr 30, 2007
      Role: Principal Investigator
      CXCR3 Chemokines in Type I Diabetes
      NIH/NIDDK R01DK066346Mar 5, 2004 - Nov 30, 2009
      Role: Principal Investigator
      How Does blockade of CD40/CD40L Prevent Autoimmunity?
      NIH/NIAID U19AI051973Sep 30, 2001 - Jul 31, 2006
      Role: Principal Investigator
      Role of a Non-Tolerant Autoantigen in Autoimmunity
      NIH/NIAID R01AI044451Sep 30, 1998 - Dec 31, 2008
      Role: Principal Investigator
      DNA Vaccination &Regulatory Cells in Type I Diabetes
      NIH/NIDDK R01DK051091Jun 1, 1996 - Nov 30, 2007
      Role: Principal Investigator
      PATHOGENESIS AND TREATMENT OF AUTOIMMUNE DIABETES
      NIH/NIDDK R29DK051091Jun 1, 1996 - May 31, 2002
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Boettler T, Schneider D, Cheng Y, Kadoya K, Brandon EP, Martinson L, von Herrath M. Pancreatic Tissue Transplanted in TheraCyte Encapsulation Devices Is Protected and Prevents Hyperglycemia in a Mouse Model of Immune-Mediated Diabetes. Cell Transplant. 2016; 25(3):609-14. PMID: 26300527.
        View in: PubMed
      2. Rodriguez-Calvo T, Suwandi JS, Amirian N, Zapardiel-Gonzalo J, Anquetil F, Sabouri S, von Herrath MG. Heterogeneity and Lobularity of Pancreatic Pathology in Type 1 Diabetes during the Prediabetic Phase. J Histochem Cytochem. 2015 Aug; 63(8):626-36. PMID: 26216138; PMCID: PMC4530397.
      3. Atkinson MA, von Herrath M, Powers AC, Clare-Salzler M. Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease. Diabetes Care. 2015 Jun; 38(6):979-88. PMID: 25998290; PMCID: PMC4439528.
      4. Rodriguez-Calvo T, von Herrath MG. Enterovirus infection and type 1 diabetes: closing in on a link? Diabetes. 2015 May; 64(5):1503-5. PMID: 25908875.
        View in: PubMed
      5. Sarikonda G, Sachithanantham S, Miller JF, Pagni PP, Coppieters KT, von Herrath M. The Hsp60 peptide p277 enhances anti-CD3 mediated diabetes remission in non-obese diabetic mice. J Autoimmun. 2015 May; 59:61-6. PMID: 25772283.
        View in: PubMed
      6. Drescher KM, von Herrath M, Tracy S. Enteroviruses, hygiene and type 1 diabetes: toward a preventive vaccine. Rev Med Virol. 2015 Jan; 25(1):19-32. PMID: 25430610.
        View in: PubMed
      7. Sarikonda G, Fousteri G, Sachithanantham S, Miller JF, Dave A, Juntti T, Coppieters KT, von Herrath M. BDC12-4.1 T-cell receptor transgenic insulin-specific CD4 T cells are resistant to in vitro differentiation into functional Foxp3+ T regulatory cells. PLoS One. 2014; 9(11):e112242. PMID: 25393309; PMCID: PMC4231041.
      8. Coppieters KT, von Herrath MG. The type 1 diabetes signature: hardwired to trigger inflammation? Diabetes. 2014 Nov; 63(11):3581-3. PMID: 25342729.
        View in: PubMed
      9. Yip L, Fuhlbrigge R, Taylor C, Creusot RJ, Nishikawa-Matsumura T, Whiting CC, Schartner JM, Akter R, von Herrath M, Fathman CG. Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes. Diabetes. 2015 Feb; 64(2):604-17. PMID: 25187368; PMCID: PMC4303971.
      10. Sarikonda G, Sachithanantham S, Pettus J, Rodriguez-Calvo T, Phatak S, Edelman S, von Herrath M. Higher proinflammatory cytokine production and spontaneous activation in some type 1 and type 2 diabetic subjects. Clin Immunol. 2014 Nov; 155(1):27-9. PMID: 25173803.
        View in: PubMed
      11. Schneider DA, von Herrath MG. Potential viral pathogenic mechanism in human type 1 diabetes. Diabetologia. 2014 Oct; 57(10):2009-18. PMID: 25073445; PMCID: PMC4153966.
      12. Fløyel T, Brorsson C, Nielsen LB, Miani M, Bang-Berthelsen CH, Friedrichsen M, Overgaard AJ, Berchtold LA, Wiberg A, Poulsen P, Hansen L, Rosinger S, Boehm BO, Ram R, Nguyen Q, Mehta M, Morahan G, Concannon P, Bergholdt R, Nielsen JH, Reinheckel T, von Herrath M, Vaag A, Eizirik DL, Mortensen HB, Størling J, Pociot F. CTSH regulates ß-cell function and disease progression in newly diagnosed type 1 diabetes patients. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10305-10. PMID: 24982147; PMCID: PMC4104872.
      13. Rodriguez-Calvo T, Ekwall O, Amirian N, Zapardiel-Gonzalo J, von Herrath MG. Increased immune cell infiltration of the exocrine pancreas: a possible contribution to the pathogenesis of type 1 diabetes. Diabetes. 2014 Nov; 63(11):3880-90. PMID: 24947367; PMCID: PMC4207385.
      14. Jones CB, Pagni PP, Fousteri G, Sachithanantham S, Dave A, Rodriguez-Calvo T, Miller J, von Herrath M. Regulatory T cells control diabetes without compromising acute anti-viral defense. Clin Immunol. 2014 Aug; 153(2):298-307. PMID: 24858581; PMCID: PMC4889438.
      15. Baca Jones C, Filippi C, Sachithanantham S, Rodriguez-Calvo T, Ehrhardt K, von Herrath M. Direct infection of dendritic cells during chronic viral infection suppresses antiviral T cell proliferation and induces IL-10 expression in CD4 T cells. PLoS One. 2014; 9(3):e90855. PMID: 24613988; PMCID: PMC3948950.
      16. Van Belle TL, Pagni PP, Liao J, Sachithanantham S, Dave A, Bel Hani A, Manenkova Y, Amirian N, Yang C, Morin B, Zhang H, Campbell IL, von Herrath MG. Beta-cell specific production of IL6 in conjunction with a mainly intracellular but not mainly surface viral protein causes diabetes. J Autoimmun. 2014 Dec; 55:24-32. PMID: 24582317; PMCID: PMC4143487.
      17. Pagni PP, Bresson D, Rodriguez-Calvo T, Bel Hani A, Manenkova Y, Amirian N, Blaszczak A, Faton S, Sachithanantham S, von Herrath MG. Combination therapy with an anti-IL-1ß antibody and GAD65 DNA vaccine can reverse recent-onset diabetes in the RIP-GP mouse model. Diabetes. 2014 Jun; 63(6):2015-25. PMID: 24520125; PMCID: PMC4030110.
      18. Coppieters KT, von Herrath MG. Metabolic syndrome - Removing roadblocks to therapy: Antigenic immunotherapies. Mol Metab. 2014 Jun; 3(3):275-83. PMID: 24749057; PMCID: PMC3986497.
      19. Sarikonda G, Pettus J, Phatak S, Sachithanantham S, Miller JF, Wesley JD, Cadag E, Chae J, Ganesan L, Mallios R, Edelman S, Peters B, von Herrath M. CD8 T-cell reactivity to islet antigens is unique to type 1 while CD4 T-cell reactivity exists in both type 1 and type 2 diabetes. J Autoimmun. 2014 May; 50:77-82. PMID: 24387802.
        View in: PubMed
      20. Sarikonda G, Pettus J, Sachithanantham S, Phatak S, Miller JF, Ganesan L, Chae J, Mallios R, Edelman S, Peters B, von Herrath M. Temporal intra-individual variation of immunological biomarkers in type 1 diabetes patients: implications for future use in cross-sectional assessment. PLoS One. 2013; 8(11):e79383. PMID: 24223938; PMCID: PMC3817042.
      21. Rydén AK, Wesley JD, Coppieters KT, Von Herrath M. Non-antigenic and antigenic interventions in type 1 diabetes. Hum Vaccin Immunother. 2014; 10(4):838-46. PMID: 24165565; PMCID: PMC4896560.
      22. Boettler T, Choi YS, Salek-Ardakani S, Cheng Y, Moeckel F, Croft M, Crotty S, von Herrath M. Exogenous OX40 stimulation during lymphocytic choriomeningitis virus infection impairs follicular Th cell differentiation and diverts CD4 T cells into the effector lineage by upregulating Blimp-1. J Immunol. 2013 Nov 15; 191(10):5026-35. PMID: 24101548; PMCID: PMC3915873.
      23. Campbell-Thompson ML, Atkinson MA, Butler AE, Chapman NM, Frisk G, Gianani R, Giepmans BN, von Herrath MG, Hyöty H, Kay TW, Korsgren O, Morgan NG, Powers AC, Pugliese A, Richardson SJ, Rowe PA, Tracy S, In't Veld PA. The diagnosis of insulitis in human type 1 diabetes. Diabetologia. 2013 Nov; 56(11):2541-3. PMID: 24006089.
        View in: PubMed
      24. Schneider DA, Sarikonda G, Montero E, von Herrath MG. Combination therapy with anti-CD6 and oral insulin immunization reverses recent onset diabetes in non obese diabetic mice but fails to induce lasting tolerance. Clin Immunol. 2013 Dec; 149(3):440-1. PMID: 24211845.
        View in: PubMed
      25. Pettus J, von Herrath M. Keeping the patient perspective: Where are we in the world of type 1 diabetes? Clin Immunol. 2013 Dec; 149(3):265-7. PMID: 24012473.
        View in: PubMed
      26. Roep BO, Solvason N, Gottlieb PA, Abreu JRF, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Garren H, Steinman L. Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8? T cells in type 1 diabetes. Sci Transl Med. 2013 Jun 26; 5(191):191ra82. PMID: 23803704; PMCID: PMC4516024.
      27. Boettler T, Pagni PP, Jaffe R, Cheng Y, Zerhouni P, von Herrath M. The clinical and immunological significance of GAD-specific autoantibody and T-cell responses in type 1 diabetes. J Autoimmun. 2013 Aug; 44:40-8. PMID: 23770292.
        View in: PubMed
      28. von Herrath M, Peakman M, Roep B. Progress in immune-based therapies for type 1 diabetes. Clin Exp Immunol. 2013 May; 172(2):186-202. PMID: 23574316; PMCID: PMC3628322.
      29. Coppieters KT, von Herrath M. Antibody cross-reactivity and the viral aetiology of type 1 diabetes. J Pathol. 2013 May; 230(1):1-3. PMID: 23389883.
        View in: PubMed
      30. Coppieters KT, Amirian N, Pagni PP, Baca Jones C, Wiberg A, Lasch S, Hintermann E, Christen U, von Herrath MG. Functional redundancy of CXCR3/CXCL10 signaling in the recruitment of diabetogenic cytotoxic T lymphocytes to pancreatic islets in a virally induced autoimmune diabetes model. Diabetes. 2013 Jul; 62(7):2492-9. PMID: 23434930; PMCID: PMC3712024.
      31. Coppieters KT, Harrison LC, von Herrath MG. Trials in type 1 diabetes: Antigen-specific therapies. Clin Immunol. 2013 Dec; 149(3):345-55. PMID: 23490422.
        View in: PubMed
      32. Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M. Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice. PLoS One. 2013; 8(2):e54712. PMID: 23405091; PMCID: PMC3566105.
      33. Christen S, Coppieters K, Rose K, Holdener M, Bayer M, Pfeilschifter JM, Hintermann E, von Herrath MG, Aurrand-Lions M, Imhof BA, Christen U. Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice. PLoS One. 2013; 8(1):e54675. PMID: 23372751; PMCID: PMC3556033.
      34. Schneider DA, Kretowicz AM, von Herrath MG. Emerging immune therapies in type 1 diabetes and pancreatic islet transplantation. Diabetes Obes Metab. 2013 Jul; 15(7):581-92. PMID: 23194064.
        View in: PubMed
      35. Vaughan K, Peters B, Mallone R, von Herrath M, Roep BO, Sette A. Navigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB). Immunome Res. 2013; 9(1). PMID: 25140192.
        View in: PubMed
      36. Coppieters KT, Sehested Hansen B, von Herrath MG. Clinical potential of antigen-specific therapies in type 1 diabetes. Rev Diabet Stud. 2012; 9(4):328-37. PMID: 23804270; PMCID: PMC3740700.
      37. Coppieters KT, Wiberg A, von Herrath MG. Viral infections and molecular mimicry in type 1 diabetes. APMIS. 2012 Dec; 120(12):941-9. PMID: 23051179.
        View in: PubMed
      38. Boettler T, Moeckel F, Cheng Y, Heeg M, Salek-Ardakani S, Crotty S, Croft M, von Herrath MG. OX40 facilitates control of a persistent virus infection. PLoS Pathog. 2012 Sep; 8(9):e1002913. PMID: 22969431; PMCID: PMC3435255.
      39. Van Belle TL, Ling E, Haase C, Bresson D, Ursø B, von Herrath MG. NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes. J Autoimmun. 2013 Feb; 40:66-73. PMID: 22944096.
        View in: PubMed
      40. Boettler T, von Herrath M. IL-7 receptor a blockade, an off-switch for autoreactive T cells. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12270-1. PMID: 22826232; PMCID: PMC3412005.
      41. Chapman NM, Coppieters K, von Herrath M, Tracy S. The microbiology of human hygiene and its impact on type 1 diabetes. Islets. 2012 Jul-Aug; 4(4):253-61. PMID: 22996796; PMCID: PMC3496651.
      42. Christen U, Bender C, von Herrath MG. Infection as a cause of type 1 diabetes? Curr Opin Rheumatol. 2012 Jul; 24(4):417-23. PMID: 22504578; PMCID: PMC4828240.
      43. Boettler T, Cheng Y, Ehrhardt K, von Herrath M. TGF-ß blockade does not improve control of an established persistent viral infection. Viral Immunol. 2012 Jun; 25(3):232-8. PMID: 22620718; PMCID: PMC3366339.
      44. Van Belle TL, Nierkens S, Arens R, von Herrath MG. Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets. Immunity. 2012 Jun 29; 36(6):1060-72. PMID: 22579473; PMCID: PMC3810457.
      45. Coppieters KT, Wiberg A, Tracy SM, von Herrath MG. Immunology in the clinic review series: focus on type 1 diabetes and viruses: the role of viruses in type 1 diabetes: a difficult dilemma. Clin Exp Immunol. 2012 Apr; 168(1):5-11. PMID: 22385231; PMCID: PMC3390487.
      46. Fousteri G, Jasinski J, Dave A, Nakayama M, Pagni P, Lambolez F, Juntti T, Sarikonda G, Cheng Y, Croft M, Cheroutre H, Eisenbarth G, von Herrath M. Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice. Diabetes. 2012 May; 61(5):1169-79. PMID: 22403296; PMCID: PMC3331775.
      47. Boettler T, Cunha-Neto E, Kalil J, von Herrath M. Can an immune-regulatory vaccine prevent HIV infection? Expert Rev Anti Infect Ther. 2012 Mar; 10(3):299-305. PMID: 22397564; PMCID: PMC3318911.
      48. Mamchak AA, Manenkova Y, Leconet W, Zheng Y, Chan JR, Stokes CL, Shoda LK, von Herrath M, Bresson D. Preexisting autoantibodies predict efficacy of oral insulin to cure autoimmune diabetes in combination with anti-CD3. Diabetes. 2012 Jun; 61(6):1490-9. PMID: 22362174; PMCID: PMC3357270.
      49. Coppieters KT, von Herrath MG. Motifs for a deadly encounter. Nat Immunol. 2012 Feb 16; 13(3):205-6. PMID: 22344274.
        View in: PubMed
      50. Blumberg RS, Dittel B, Hafler D, von Herrath M, Nestle FO. Unraveling the autoimmune translational research process layer by layer. Nat Med. 2012 Jan 06; 18(1):35-41. PMID: 22227670; PMCID: PMC4592149.
      51. Coppieters KT, Dotta F, Amirian N, Campbell PD, Kay TW, Atkinson MA, Roep BO, von Herrath MG. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J Exp Med. 2012 Jan 16; 209(1):51-60. PMID: 22213807; PMCID: PMC3260877.
      52. Coppieters KT, Boettler T, von Herrath M. Virus infections in type 1 diabetes. Cold Spring Harb Perspect Med. 2012 Jan; 2(1):a007682. PMID: 22315719; PMCID: PMC3253029.
      53. Suchkov SV, Rose N, Notkins A, Golubnichaia O, von Herrath M, Legg M, Marshall T. [Introduction to preventive and predictive medicine: past experience and future reality]. Ter Arkh. 2012; 84(8):81-5. PMID: 22994097.
        View in: PubMed
      54. Schneider DA, Sarikonda G, von Herrath MG. Combination therapy with InsB9-23 peptide immunization and CTLA4-IgG does not reverse diabetes in NOD mice. Clin Immunol. 2012 Mar; 142(3):402-3. PMID: 22239953.
        View in: PubMed
      55. Coppieters K, Amirian N, von Herrath M. Intravital imaging of CTLs killing islet cells in diabetic mice. J Clin Invest. 2012 Jan; 122(1):119-31. PMID: 22133877; PMCID: PMC3248300.
      56. Bresson D, Fousteri G, Manenkova Y, Croft M, von Herrath M. Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment. J Autoimmun. 2011 Dec; 37(4):342-51. PMID: 22063316; PMCID: PMC3811160.
      57. Coppieters KT, Wiberg A, Amirian N, Kay TW, von Herrath MG. Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals. Diabetes Metab Res Rev. 2011 Nov; 27(8):746-54. PMID: 22069254.
        View in: PubMed
      58. Coppieters KT, von Herrath MG. Viruses and cytotoxic T lymphocytes in type 1 diabetes. Clin Rev Allergy Immunol. 2011 Oct; 41(2):169-78. PMID: 21181304.
        View in: PubMed
      59. von Herrath M, Filippi C, Coppieters K. How viral infections enhance or prevent type 1 diabetes-from mouse to man. J Med Virol. 2011 Sep; 83(9):1672. PMID: 21739461.
        View in: PubMed
      60. Van Belle TL, Esplugues E, Liao J, Juntti T, Flavell RA, von Herrath MG. Development of autoimmune diabetes in the absence of detectable IL-17A in a CD8-driven virally induced model. J Immunol. 2011 Sep 15; 187(6):2915-22. PMID: 21832162; PMCID: PMC3169711.
      61. Michels AW, von Herrath M. 2011 Update: antigen-specific therapy in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes. 2011 Aug; 18(4):235-40. PMID: 21844706; PMCID: PMC4016762.
      62. Coppieters KT, Amirian N, von Herrath MG. Incidental CD8 T cell reactivity against caspase-cleaved apoptotic self-antigens from ubiquitously expressed proteins in islets from prediabetic human leucocyte antigen-A2 transgenic non-obese diabetic mice. Clin Exp Immunol. 2011 Aug; 165(2):155-62. PMID: 21605113; PMCID: PMC3142640.
      63. Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or ß-cell suicide revisited. Diabetes. 2011 May; 60(5):1370-9. PMID: 21525508; PMCID: PMC3292309.
      64. Filippi CM, Ehrhardt K, Estes EA, Larsson P, Oldham JE, von Herrath MG. TLR2 signaling improves immunoregulation to prevent type 1 diabetes. Eur J Immunol. 2011 May; 41(5):1399-409. PMID: 21469083; PMCID: PMC3100206.
      65. Diana J, Brezar V, Beaudoin L, Dalod M, Mellor A, Tafuri A, von Herrath M, Boitard C, Mallone R, Lehuen A. Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay. J Exp Med. 2011 Apr 11; 208(4):729-45. PMID: 21444661; PMCID: PMC3135349.
      66. Fousteri G, Dave A, Morin B, Omid S, Croft M, von Herrath MG. Nasal cardiac myosin peptide treatment and OX40 blockade protect mice from acute and chronic virally-induced myocarditis. J Autoimmun. 2011 May; 36(3-4):210-20. PMID: 21333491; PMCID: PMC3079777.
      67. Bresson D, von Herrath M. Humanizing animal models: a key to autoimmune diabetes treatment. Sci Transl Med. 2011 Feb 02; 3(68):68ps4. PMID: 21289271; PMCID: PMC3137650.
      68. Christen U, von Herrath MG. Do viral infections protect from or enhance type 1 diabetes and how can we tell the difference? Cell Mol Immunol. 2011 May; 8(3):193-8. PMID: 21258361; PMCID: PMC4012874.
      69. Bresson D, von Herrath MG. Anti-thymoglobulin (ATG) treatment does not reverse type 1 diabetes in the acute virally induced rat insulin promoter-lymphocytic choriomeningitis virus (RIP-LCMV) model. Clin Exp Immunol. 2011 Mar; 163(3):375-80. PMID: 21235534; PMCID: PMC3048622.
      70. Fousteri G, Dave A, Juedes A, Juntti T, Morin B, Togher L, Farber DL, von Herrath M. Increased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure. PLoS One. 2011 Jan 06; 6(1):e14502. PMID: 21253594; PMCID: PMC3017078.
      71. van Belle TL, Coppieters KT, von Herrath MG. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev. 2011 Jan; 91(1):79-118. PMID: 21248163.
        View in: PubMed
      72. Sarikonda G, von Herrath MG. Immunosuppressive mechanisms during viral infectious diseases. Methods Mol Biol. 2011; 677:431-47. PMID: 20941625.
        View in: PubMed
      73. Boettler T, von Herrath M. Type 1 diabetes vaccine development: animal models vs. humans. Hum Vaccin. 2011 Jan 01; 7(1):19-26. PMID: 21157185.
        View in: PubMed
      74. Boettler T, von Herrath M. Protection against or triggering of Type 1 diabetes? Different roles for viral infections. Expert Rev Clin Immunol. 2011 Jan; 7(1):45-53. PMID: 21162649; PMCID: PMC3077770.
      75. Coppieters K, Martinic MM, Kiosses WB, Amirian N, von Herrath M. A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy. PLoS One. 2010 Dec 23; 5(12):e15732. PMID: 21203413; PMCID: PMC3009738.
      76. Coppieters KT, Roep BO, von Herrath MG. Beta cells under attack: toward a better understanding of type 1 diabetes immunopathology. Semin Immunopathol. 2011 Jan; 33(1):1-7. PMID: 21170533.
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      77. Martinic MM, Huber C, Coppieters K, Oldham JE, Gavin AL, von Herrath MG. Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis. J Autoimmun. 2010 Dec; 35(4):404-13. PMID: 20932718; PMCID: PMC2963714.
      78. Fousteri G, Chan JR, Zheng Y, Whiting C, Dave A, Bresson D, Croft M, von Herrath M. Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection. Diabetes. 2010 Dec; 59(12):3148-58. PMID: 20864513; PMCID: PMC2992777.
      79. Peakman M, von Herrath M. Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential. Diabetes. 2010 Sep; 59(9):2087-93. PMID: 20805382; PMCID: PMC2927927.
      80. Boettler T, von Herrath M. Immunotherapy of type 1 diabetes--how to rationally prioritize combination therapies in T1D. Int Immunopharmacol. 2010 Dec; 10(12):1491-5. PMID: 20667487.
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      81. Fousteri G, Dave A, Juntti T, Morin B, McClure M, Von Herrath M. Minimal effect of CD103 expression on the control of a chronic antiviral immune response. Viral Immunol. 2010 Jun; 23(3):285-94. PMID: 20565292; PMCID: PMC2942862.
      82. Fousteri G, Dave A, Bot A, Juntti T, Omid S, von Herrath M. Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma. Diabetologia. 2010 Sep; 53(9):1958-70. PMID: 20490452; PMCID: PMC2910887.
      83. Rottembourg D, Filippi CM, Bresson D, Ehrhardt K, Estes EA, Oldham JE, von Herrath MG. Essential role for TLR9 in prime but not prime-boost plasmid DNA vaccination to activate dendritic cells and protect from lethal viral infection. J Immunol. 2010 Jun 15; 184(12):7100-7. PMID: 20483769; PMCID: PMC3128449.
      84. von Herrath M. Combination therapies for type 1 diabetes: why not now? Immunotherapy. 2010 May; 2(3):289-91. PMID: 20635894.
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      85. Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M. Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol. 2010 May; 160(2):176-84. PMID: 20629979; PMCID: PMC2857940.
      86. Filippi CM, von Herrath MG. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: viruses, autoimmunity and immunoregulation. Clin Exp Immunol. 2010 Apr; 160(1):113-9. PMID: 20415860; PMCID: PMC2841844.
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      182. Petersen JS, Bregenholt S, Apostolopolous V, Homann D, Wolfe T, Hughes A, De Jongh K, Wang M, Dyrberg T, Von Herrath M. Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes. Clin Exp Immunol. 2003 Oct; 134(1):38-45. PMID: 12974752; PMCID: PMC1808831.
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      191. Christen U, von Herrath MG. Transgenic animal models for type 1 diabetes: linking a tetracycline-inducible promoter with a virus-inducible mouse model. Transgenic Res. 2002 Dec; 11(6):587-95. PMID: 12509133.
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      197. Christen U, Von Herrath M. Apoptosis of autoreactive CD8 lymphocytes as a potential mechanism for the abrogation of type 1 diabetes by islet-specific TNF-alpha expression at a time when the autoimmune process is already ongoing. Ann N Y Acad Sci. 2002 Apr; 958:166-9. PMID: 12021099.
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      198. von Herrath M, Bach JF. Juvenile autoimmune diabetes: a pathogenic role for maternal antibodies? Nat Med. 2002 Apr; 8(4):331-3. PMID: 11927933.
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      199. Homann D, Jahreis A, Wolfe T, Hughes A, Coon B, van Stipdonk MJ, Prilliman KR, Schoenberger SP, von Herrath MG. CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells. Immunity. 2002 Mar; 16(3):403-15. PMID: 11911825.
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      200. Hugues S, Mougneau E, Ferlin W, Jeske D, Hofman P, Homann D, Beaudoin L, Schrike C, Von Herrath M, Lehuen A, Glaichenhaus N. Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells. Immunity. 2002 Feb; 16(2):169-81. PMID: 11869679.
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      201. von Herrath MG, Coon B, Wolfe T, Chatenoud L. Nonmitogenic CD3 antibody reverses virally induced (rat insulin promoter-lymphocytic choriomeningitis virus) autoimmune diabetes without impeding viral clearance. J Immunol. 2002 Jan 15; 168(2):933-41. PMID: 11777992.
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      202. Wolfe T, Bot A, Hughes A, Möhrle U, Rodrigo E, Jaume JC, Baekkeskov S, von Herrath M. Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety. Eur J Immunol. 2002 Jan; 32(1):113-21. PMID: 11754351.
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      203. von Herrath MG. Regulation of virally induced autoimmunity and immunopathology: contribution of LCMV transgenic models to understanding autoimmune insulin-dependent diabetes mellitus. Curr Top Microbiol Immunol. 2002; 263:145-75. PMID: 11987813.
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      204. von Herrath MG, Wolfe T, Möhrle U, Coon B, Hughes A. Protection from type 1 diabetes in the face of high levels of activated autoaggressive lymphocytes in a viral transgenic mouse model crossed to the SV129 strain. Diabetes. 2001 Dec; 50(12):2700-8. PMID: 11723052.
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      205. Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, von Herrath M, Wegmann D, Wen L, Zekzer D. Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop. Diabetes. 2001 Nov; 50(11):2459-63. PMID: 11679422.
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      206. Bot A, Smith D, Bot S, Hughes A, Wolfe T, Wang L, Woods C, von Herrath M. Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice. J Immunol. 2001 Sep 01; 167(5):2950-5. PMID: 11509644.
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      207. Christen U, Wolfe T, Möhrle U, Hughes AC, Rodrigo E, Green EA, Flavell RA, von Herrath MG. A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis. J Immunol. 2001 Jun 15; 166(12):7023-32. PMID: 11390446.
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      208. von Herrath MG, Coon B, Wolfe T. Tolerance induction with agonist peptides recognized by autoaggressive lymphocytes is transient: therapeutic potential for type 1 diabetes is limited and depends on time-point of administration, choice of epitope and adjuvant. J Autoimmun. 2001 May; 16(3):193-9. PMID: 11334483.
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      209. von Herrath M, Whitton JL. Animal models using lymphocytic choriomeningitis virus. Curr Protoc Immunol. 2001 May; Chapter 19:Unit 19.10. PMID: 18432751.
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      210. Hudrisier D, Riond J, Burlet-Schiltz O, von Herrath MG, Lewicki H, Monsarrat B, Oldstone MB, Gairin JE. Structural and functional identification of major histocompatibility complex class I-restricted self-peptides as naturally occurring molecular mimics of viral antigens. Possible role in CD8+ T cell-mediated, virus-induced autoimmune disease. J Biol Chem. 2001 Jun 01; 276(22):19396-403. PMID: 11278441.
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      211. Pauza ME, Nguyen A, Wolfe T, Ho IC, Glimcher LH, von Herrath M, Lo D. Variable effects of transgenic c-Maf on autoimmune diabetes. Diabetes. 2001 Jan; 50(1):39-46. PMID: 11147792.
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      212. von Herrath MG, Oldstone M, Homann D, Christen U. Is activation of autoreactive lymphocytes always detrimental? Viral infections and regulatory circuits in autoimmunity. Curr Dir Autoimmun. 2001; 4:91-122. PMID: 11569412.
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      213. von Herrath MG. Design of immune-based interventions in autoimmunity and viral infections--the need for predictive models that integrate time, dose and classes of immune responses. Novartis Found Symp. 2001; 239:16-24; discussion 24-30, 45-51. PMID: 11529309.
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      214. Holz A, Dyrberg T, Hagopian W, Homann D, von Herrath M, Oldstone MB. Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes. J Immunol. 2000 Nov 15; 165(10):5945-53. PMID: 11067957.
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      215. Seewaldt S, Thomas HE, Ejrnaes M, Christen U, Wolfe T, Rodrigo E, Coon B, Michelsen B, Kay TW, von Herrath MG. Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes. Diabetes. 2000 Nov; 49(11):1801-9. PMID: 11078446.
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      216. von Herrath MG. Obstacles to identifying viruses that cause autoimmune disease. J Neuroimmunol. 2000 Jul 24; 107(2):154-60. PMID: 10854650.
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      217. von Herrath MG, Whitton JL. DNA vaccination to treat autoimmune diabetes. Ann Med. 2000 Jul; 32(5):285-92. PMID: 10949059.
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      218. Sevilla N, Homann D, von Herrath M, Rodriguez F, Harkins S, Whitton JL, Oldstone MB. Virus-induced diabetes in a transgenic model: role of cross-reacting viruses and quantitation of effector T cells needed to cause disease. J Virol. 2000 Apr; 74(7):3284-92. PMID: 10708445; PMCID: PMC111829.
      219. Subauste MC, Von Herrath M, Benard V, Chamberlain CE, Chuang TH, Chu K, Bokoch GM, Hahn KM. Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas. J Biol Chem. 2000 Mar 31; 275(13):9725-33. PMID: 10734125.
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      220. Bot A, Holz A, Christen U, Wolfe T, Temann A, Flavell R, von Herrath M. Local IL-4 expression in the lung reduces pulmonary influenza-virus-specific secondary cytotoxic T cell responses. Virology. 2000 Mar 30; 269(1):66-77. PMID: 10725199.
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      221. von Herrath MG, Berger DP, Homann D, Tishon T, Sette A, Oldstone MB. Vaccination to treat persistent viral infection. Virology. 2000 Mar 15; 268(2):411-9. PMID: 10704349.
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      222. Preckel T, Fung-Leung WP, Cai Z, Vitiello A, Salter-Cid L, Winqvist O, Wolfe TG, Von Herrath M, Angulo A, Ghazal P, Lee JD, Fourie AM, Wu Y, Pang J, Ngo K, Peterson PA, Früh K, Yang Y. Impaired immunoproteasome assembly and immune responses in PA28-/- mice. Science. 1999 Dec 10; 286(5447):2162-5. PMID: 10591649.
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      223. Holz A, Bot A, Coon B, Wolfe T, Grusby MJ, von Herrath MG. Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence. J Immunol. 1999 Nov 15; 163(10):5374-82. PMID: 10553062.
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      224. Homann D, Holz A, Bot A, Coon B, Wolfe T, Petersen J, Dyrberg TP, Grusby MJ, von Herrath MG. Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway. Immunity. 1999 Oct; 11(4):463-72. PMID: 10549628.
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      225. Homann D, Dyrberg T, Petersen J, Oldstone MB, von Herrath MG. Insulin in oral immune "tolerance": a one-amino acid change in the B chain makes the difference. J Immunol. 1999 Aug 15; 163(4):1833-8. PMID: 10438916.
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      226. von Herrath M, Coon B, Homann D, Wolfe T, Guidotti LG. Thymic tolerance to only one viral protein reduces lymphocytic choriomeningitis virus-induced immunopathology and increases survival in perforin-deficient mice. J Virol. 1999 Jul; 73(7):5918-25. PMID: 10364344; PMCID: PMC112653.
      227. Coon B, An LL, Whitton JL, von Herrath MG. DNA immunization to prevent autoimmune diabetes. J Clin Invest. 1999 Jul; 104(2):189-94. PMID: 10411548; PMCID: PMC408480.
      228. Oldstone MB, von Herrath M, Lewicki H, Hudrisier D, Whitton JL, Gairin JE. Use of a high-affinity peptide that aborts MHC-restricted cytotoxic T lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo. Virology. 1999 Apr 10; 256(2):246-57. PMID: 10191190.
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      229. von Herrath MG. Selective immunotherapy of IDDM: a discussion based on new findings from the RIP-LCMV model for autoimmune diabetes. Transplant Proc. 1998 Dec; 30(8):4115-21. PMID: 9865317.
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      230. Homann D, Tishon A, Berger DP, Weigle WO, von Herrath MG, Oldstone MB. Evidence for an underlying CD4 helper and CD8 T-cell defect in B-cell-deficient mice: failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from muMT/muMT mice. J Virol. 1998 Nov; 72(11):9208-16. PMID: 9765468; PMCID: PMC110340.
      231. von Herrath MG, Coon B, Lewicki H, Mazarguil H, Gairin JE, Oldstone MB. In vivo treatment with a MHC class I-restricted blocking peptide can prevent virus-induced autoimmune diabetes. J Immunol. 1998 Nov 01; 161(9):5087-96. PMID: 9794447.
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      232. von Herrath MG, Holz A, Homann D, Oldstone MB. Role of viruses in type I diabetes. Semin Immunol. 1998 Feb; 10(1):87-100. PMID: 9529659.
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      233. von Herrath MG. Bystander suppression induced by oral tolerance. Res Immunol. 1997 Oct-Dec; 148(8-9):541-54. PMID: 9588833.
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      234. von Herrath MG, Efrat S, Oldstone MB, Horwitz MS. Expression of adenoviral E3 transgenes in beta cells prevents autoimmune diabetes. Proc Natl Acad Sci U S A. 1997 Sep 02; 94(18):9808-13. PMID: 9275207; PMCID: PMC23273.
      235. von Herrath M, Holz A. Pathological changes in the islet milieu precede infiltration of islets and destruction of beta-cells by autoreactive lymphocytes in a transgenic model of virus-induced IDDM. J Autoimmun. 1997 Jun; 10(3):231-8. PMID: 9218748.
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      236. von Herrath MG, Homann D, Gairin JE, Oldstone MB. Pathogenesis and treatment of virus-induced autoimmune diabetes: novel insights gained from the RIP-LCMV transgenic mouse model. Biochem Soc Trans. 1997 May; 25(2):630-5. PMID: 9191170.
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      237. Von Herrath M, Coon B, Oldstone MB. Low-affinity cytotoxic T-lymphocytes require IFN-gamma to clear an acute viral infection. Virology. 1997 Mar 17; 229(2):349-59. PMID: 9126248.
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      238. von Herrath MG, Oldstone MB. Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus. J Exp Med. 1997 Feb 03; 185(3):531-9. PMID: 9053453; PMCID: PMC2196037.
      239. von Herrath MG, Oldstone MB. Virus-induced autoimmune disease. Curr Opin Immunol. 1996 Dec; 8(6):878-85. PMID: 8994870.
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      240. Oldstone MB, von Herrath M. Virus-induced autoimmune disease: transgenic approach to mimic insulin-dependent diabetes mellitus and other autoimmune diseases. APMIS. 1996 Oct; 104(10):689-97. PMID: 8980618.
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      241. von Herrath MG, Dyrberg T, Oldstone MB. Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice. J Clin Invest. 1996 Sep 15; 98(6):1324-31. PMID: 8823297; PMCID: PMC507558.
      242. von Herrath MG, Evans CF, Horwitz MS, Oldstone MB. Using transgenic mouse models to dissect the pathogenesis of virus-induced autoimmune disorders of the islets of Langerhans and the central nervous system. Immunol Rev. 1996 Aug; 152:111-43. PMID: 8930670.
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      243. Lee MS, Sawyer S, Arnush M, Krahl T, von Herrath M, Oldstone MA, Sarvetnick N. Transforming growth factor-beta fails to inhibit allograft rejection or virus-induced autoimmune diabetes in transgenic mice. Transplantation. 1996 Apr 15; 61(7):1112-5. PMID: 8623195.
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      244. von Herrath MG, Yokoyama M, Dockter J, Oldstone MB, Whitton JL. CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge. J Virol. 1996 Feb; 70(2):1072-9. PMID: 8551565; PMCID: PMC189913.
      245. Oldstone MB, von Herrath M, Evans CF, Horwitz MS. Virus-induced autoimmune disease: transgenic approach to mimic insulin-dependent diabetes mellitus and multiple sclerosis. Curr Top Microbiol Immunol. 1996; 206:67-83. PMID: 8608726.
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      246. von Herrath MG, Guerder S, Lewicki H, Flavell RA, Oldstone MB. Coexpression of B7-1 and viral ("self") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes. Immunity. 1995 Dec; 3(6):727-38. PMID: 8777718.
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      247. von Herrath MG, Oldstone MB. Role of viruses in the loss of tolerance to self-antigens and in autoimmune diseases. Trends Microbiol. 1995 Nov; 3(11):424-30. PMID: 8574515.
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      248. Tishon A, Lewicki H, Rall G, Von Herrath M, Oldstone MB. An essential role for type 1 interferon-gamma in terminating persistent viral infection. Virology. 1995 Sep 10; 212(1):244-50. PMID: 7676639.
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      249. Lewicki HA, Von Herrath M, Evans CF, Whitton JL, Oldstone MB. CTL escape viral variants. II. Biologic activity in vivo. Virology. 1995 Aug 20; 211(2):443-50. PMID: 7645248.
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      250. von Herrath M, Oldstone MB, Fox HS. Simian immunodeficiency virus (SIV)-specific CTL in cerebrospinal fluid and brains of SIV-infected rhesus macaques. J Immunol. 1995 May 15; 154(10):5582-9. PMID: 7730657.
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      251. Lee MS, von Herrath M, Reiser H, Oldstone MB, Sarvetnick N. Sensitization to self (virus) antigen by in situ expression of murine interferon-gamma. J Clin Invest. 1995 Feb; 95(2):486-92. PMID: 7860730; PMCID: PMC295495.
      252. von Herrath MG, Allison J, Miller JF, Oldstone MB. Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response. J Clin Invest. 1995 Feb; 95(2):477-85. PMID: 7860729; PMCID: PMC295493.
      253. von Herrath MG, Dockter J, Nerenberg M, Gairin JE, Oldstone MB. Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus. J Exp Med. 1994 Nov 01; 180(5):1901-10. PMID: 7525843; PMCID: PMC2191719.
      254. von Herrath MG, Dockter J, Oldstone MB. How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity. 1994 Jun; 1(3):231-42. PMID: 7889411.
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      255. Laufer TM, von Herrath MG, Grusby MJ, Oldstone MB, Glimcher LH. Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice. J Exp Med. 1993 Aug 01; 178(2):589-96. PMID: 8101862; PMCID: PMC2191112.
      256. von Herrath M, Hasenfuss G, Holubarsch C, Hofmann T, Heiss HW, Just H. Repeat determination of left ventricular wall thickness from mass and volume during one cardiac cycle for the calculation of left ventricular wall stress parameters. Clin Cardiol. 1990 Mar; 13(3):218-20. PMID: 2323121.
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      257. Hasenfuss G, Holubarsch C, Heiss HW, von Herrath M, Just H. Coupling between myocardial oxygen consumption and mechanics in patients with dilative cardiomyopathy. Influence of vasodilation and positive inotropism. Prog Clin Biol Res. 1989; 315:613-5. PMID: 2529573.
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      258. von Herrath M, Holzer H. Sensitivity of fructose-1,6-biphosphatase from yeast, liver and skeletal muscle to fructose-2,6-biphosphate and 5'-adenosine monophosphate. Z Lebensm Unters Forsch. 1988 May; 186(5):427-30. PMID: 3291467.
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      259. Nakatani Y, Banner C, von Herrath M, Schneider ME, Smith HH, Freese E. Comparison of human brain and liver glutamate dehydrogenase cDNAS. Biochem Biophys Res Commun. 1987 Dec 16; 149(2):405-10. PMID: 3426581.
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      260. Holubarsch C, Hasenfuss G, Chen C, von Herrath M, Krehl F, Bonzel T, Just H. Acute effects of nitrates on left ventricular performance and energetics. Z Kardiol. 1986; 75 Suppl 3:35-7. PMID: 3099485.
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      261. Holubarsch C, Hasenfuss G, Körner M, von Herrath M, Bonzel T, Tarnowska R, Just H. Myocardial performance and efficiency as assessed by energetic parameters derived from pressure-volume relations and wall thickness in human ventricles. Z Kardiol. 1986; 75 Suppl 2:100-4. PMID: 3727668.
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      262. Pohlig G, Schäfer W, von Herrath M, Holzer H. Modification of yeast fructose-1,6-bisphosphatase. Curr Top Cell Regul. 1985; 27:317-25. PMID: 3004823.
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      263. von Herrath M, Holzer H. Oxidative inactivation of yeast fructose-1,6-bisphosphatase. Prog Clin Biol Res. 1985; 180:329-40. PMID: 2994088.
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