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    Jonathan Hagopian

    TitleAssistant Clinical Professor
    SchoolUniversity of California, San Diego
    DepartmentSchool of Pharmacy and Pharmaceutical Science
    Address9500 Gilman Drive #0719
    CA La Jolla 92093
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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Meade BR, Gogoi K, Hamil AS, Palm-Apergi C, Berg Av, Hagopian J, Springer AD, Eguchi A, Kacsinta AD, Dowdy CF, Presente A, Lönn P, Kaulich M, Yoshioka N, Gros E, Cui XS, Dowdy SF. Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications. Nat Biotechnol. 2014 Dec; 32(12):1256-61. PMID: 25402614.
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      2. Aubol BE, Plocinik RM, Keshwani MM, McGlone ML, Hagopian J, Ghosh G, Fu XD, Adams JA. N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation. Biochem J. 2014 Aug 15; 462(1):143-52. PMID: 24869919.
        View in: PubMed
      3. Aubol BE, Plocinik RM, Hagopian J, Ma CT, McGlone ML, Bandyopadhyay R, Fu XD, Adams JA. Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases. J Mol Biol. 2013 Aug 23; 425(16):2894-909. PMID: 23707382.
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      4. Huynh N, Ma CT, Giang N, Hagopian J, Ngo J, Adams J, Ghosh G. Allosteric interactions direct binding and phosphorylation of ASF/SF2 by SRPK1. Biochemistry. 2009 Dec 8; 48(48):11432-40. PMID: 19886675.
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      5. Ma CT, Hagopian J, Ghosh G, Fu XD, Adams JA. Regiospecific phosphorylation control of the SR protein ASF/SF2 by SRPK1. J Mol Biol. 2009 Jul 24; 390(4):618-34. PMID: 19477182.
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      6. Hagopian J, Ma CT, Meade BR, Albuquerque CP, Ngo JC, Ghosh G, Jennings PA, Fu XD, Adams JA. Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1. J Mol Biol. 2008 Oct 17; 382(4):894-909. PMID: 18687337.
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      7. Ngo JC, Giang K, Chakrabarti S, Ma CT, Huynh N, Hagopian J, Dorrestein PC, Fu XD, Adams JA, Ghosh G. A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1. Mol Cell. 2008 Mar 14; 29(5):563-76. PMID: 18342604.
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      8. Ma CT, Velazquez-Dones A, Hagopian J, Ghosh G, Fu XD, Adams JA. Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1. J Mol Biol. 2008 Feb 8; 376(1):55-68. PMID: 18155240.
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      9. Lukasiewicz R, Velazquez-Dones A, Huynh N, Hagopian J, Fu XD, Adams J, Ghosh G. Structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions. J Biol Chem. 2007 Aug 10; 282(32):23036-43. PMID: 17517895.
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      10. Ding JH, Zhong XY, Hagopian J, Cruz MM, Ghosh G, Feramisco J, Adams JA, Fu XD. Regulated cellular partitioning of SR protein-specific kinases in mammalian cells. Mol Biol Cell. 2006 Feb; 17(2):876-85. PMID: 16319169.
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      11. Velazquez-Dones A, Hagopian J, Ma CT, Zhong XY, Zhou H, Ghosh G, Fu XD, Adams JA. Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. J Biol Chem. 2005 Dec 16; 280(50):41761-8. PMID: 16223727.
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      12. Hagopian J, Reis M, Kitajima JP, Bhattacharya D, de Oliveira MC. Comparative analysis of the complete plastid genome sequence of the red alga Gracilaria tenuistipitata var. liui provides insights into the evolution of rhodoplasts and their relationship to other plastids. J Mol Evol. 2004 Oct; 59(4):464-77. PMID: 15638458.
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      13. Stevenson LM, Deal MS, Hagopian J, Lew J. Activation mechanism of CDK2: role of cyclin binding versus phosphorylation. Biochemistry. 2002 Jul 2; 41(26):8528-34. PMID: 12081504.
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      14. Hagopian J, Kirtley MP, Stevenson LM, Gergis RM, Russo AA, Pavletich NP, Parsons SM, Lew J. Kinetic basis for activation of CDK2/cyclin A by phosphorylation. J Biol Chem. 2001 Jan 5; 276(1):275-80. PMID: 11029468.
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      15. Prowse CN, Hagopian J, Cobb MH, Ahn NG, Lew J. Catalytic reaction pathway for the mitogen-activated protein kinase ERK2. Biochemistry. 2000 May 23; 39(20):6258-66. PMID: 10821702.
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