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    John Lapek

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentPharmacology
    Address9500 Gilman Drive #0636
    CA La Jolla 92093
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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Lapek J, Greninger P, Morris R, Amzallag A, Pruteanu-Malinici I, Benes CH, Haas W. Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities. Nat Biotechnol. 2017 Sep 11. PMID: 28892078.
        View in: PubMed
      2. Lapek J, Fang RH, Wei X, Li P, Wang B, Zhang L, Gonzalez DJ. Biomimetic Virulomics for Capture and Identification of Cell-Type Specific Effector Proteins. ACS Nano. 2017 Sep 11. PMID: 28892626.
        View in: PubMed
      3. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek J, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. 2017 Aug 02. PMID: 28770317.
        View in: PubMed
      4. Lapek J, Lewinski MK, Wozniak JM, Guatelli J, Gonzalez DJ. Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Vpr. Mol Cell Proteomics. 2017 Jun 12. PMID: 28606917.
        View in: PubMed
      5. Nicolay BN, Danielian PS, Kottakis F, Lapek J, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, Dyson NJ. Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation. Genes Dev. 2015 Sep 1; 29(17):1875-89. PMID: 26314710.
        View in: PubMed
      6. Lapek J, Tombline G, Kellersberger KA, Friedman MR, Friedman AE. Evidence of histidine and aspartic acid phosphorylation in human prostate cancer cells. Naunyn Schmiedebergs Arch Pharmacol. 2015 Feb; 388(2):161-73. PMID: 25373728.
        View in: PubMed
      7. Tombline G, Schwingel JM, Lapek J, Friedman AE, Darrah T, Maguire M, Van Alst NE, Filiatrault MJ, Iglewski BH. Pseudomonas aeruginosa PA1006 is a persulfide-modified protein that is critical for molybdenum homeostasis. PLoS One. 2013; 8(2):e55593. PMID: 23409003; PMCID: PMC3568144.
      8. Badding MA, Lapek J, Friedman AE, Dean DA. Proteomic and functional analyses of protein-DNA complexes during gene transfer. Mol Ther. 2013 Apr; 21(4):775-85. PMID: 23164933; PMCID: PMC3616537.
      9. MacGilvray ME, Lapek J, Friedman AE, Quivey RG. Cardiolipin biosynthesis in Streptococcus mutans is regulated in response to external pH. Microbiology. 2012 Aug; 158(Pt 8):2133-43. PMID: 22628481; PMCID: PMC3542136.
      10. Lapek J, McGrath JL, Ricke WA, Friedman AE. LC/LC-MS/MS of an innovative prostate human epithelial cancer (PHEC) in vitro model system. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Apr 15; 893-894:34-42. PMID: 22425387; NIHMSID: NIHMS361250.
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      11. Sundar IK, Chung S, Hwang JW, Lapek J, Bulger M, Friedman AE, Yao H, Davie JR, Rahman I. Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-?B-dependent genes. PLoS One. 2012; 7(2):e31378. PMID: 22312446; PMCID: PMC3270039.
      12. Lapek J, Tombline G, Friedman AE. Mass spectrometry detection of histidine phosphorylation on NM23-H1. J Proteome Res. 2011 Feb 4; 10(2):751-5. PMID: 21121676; NIHMSID: NIHMS261256.
        View in: PubMed
      13. Isabella VM, Lapek J, Kennedy EM, Clark VL. Functional analysis of NsrR, a nitric oxide-sensing Rrf2 repressor in Neisseria gonorrhoeae. Mol Microbiol. 2009 Jan; 71(1):227-39. PMID: 19007408; NIHMSID: NIHMS75709.
        View in: PubMed