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    John Bradley

    TitleProfessor Of Clinical
    SchoolUniversity of California, San Diego
    DepartmentPediatrics
    Address9500 Gilman Drive #0984
    CA La Jolla 92093
    Phone858-966-7785
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Developmental and Translational Pharmacology of Pediatric Antimicrobial Therapy
      NIH U54HD071600Sep 26, 2011 - Jun 30, 2016
      Role: Co-Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Natale S, Bradley J, Nguyen WH, Tran T, Ny P, La K, Vivian E, Le J. Pediatric Obesity: Pharmacokinetic Alterations and Effects on Antimicrobial Dosing. Pharmacotherapy. 2017 Jan 12. PMID: 28079262.
        View in: PubMed
      2. Gonzalez D, Bradley J, Blumer J, Yogev R, Watt KM, James LP, Palazzi DL, Bhatt-Mehta V, Sullivan JE, Zhang L, Murphy J, Ussery XT, Puttagunta S, Dunne MW, Cohen-Wolkowiez M. Dalbavancin Pharmacokinetics and Safety in Children 3 Months to 11 Years of Age. Pediatr Infect Dis J. 2017 Jan 03. PMID: 28060045.
        View in: PubMed
      3. Olarte L, Lin PL, Barson WJ, Romero JR, Tan TQ, Givner LB, Hoffman JA, Bradley J, Hultén KG, Mason EO, Kaplan SL. Invasive pneumococcal infections in children following transplantation in the pneumococcal conjugate vaccine era. Transpl Infect Dis. 2016 Nov 9. PMID: 27862712.
        View in: PubMed
      4. Olarte L, Kaplan SL, Barson WJ, Romero JR, Lin PL, Tan TQ, Hoffman JA, Bradley J, Givner LB, Mason EO, Hultén KG. Emergence of Multidrug-resistant Pneumococcal Serotype 35B among U.S. Children. J Clin Microbiol. 2016 Nov 9. PMID: 27847379.
        View in: PubMed
      5. Riccobene TA, Khariton T, Knebel W, Das S, Li J, Jandourek A, Carrothers TJ, Bradley J. Population PK Modeling and Target Attainment Simulations to Support Dosing of Ceftaroline Fosamil in Pediatric Patients With Acute Bacterial Skin and Skin Structure Infections and Community-Acquired Bacterial Pneumonia. J Clin Pharmacol. 2017 Mar; 57(3):345-355. PMID: 27510635.
        View in: PubMed
      6. Bradley J, Armstrong J, Arrieta A, Bishai R, Das S, Delair S, Edeki T, Holmes WC, Li J, Moffett KS, Mukundan D, Perez N, Romero JR, Speicher D, Sullivan JE, Zhou D. Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. Antimicrob Agents Chemother. 2016 Oct; 60(10):6252-9. PMID: 27503642.
        View in: PubMed
      7. Korczowski B, Antadze T, Giorgobiani M, Stryjewski ME, Jandourek A, Smith A, O'Neal T, Bradley J. A Multicenter, Randomized, Observer-blinded, Active-controlled Study to Evaluate the Safety and Efficacy of Ceftaroline Versus Comparator in Pediatric Patients With Acute Bacterial Skin and Skin Structure Infection. Pediatr Infect Dis J. 2016 Aug; 35(8):e239-47. PMID: 27164462.
        View in: PubMed
      8. Blumer JL, Ghonghadze T, Cannavino C, O'Neal T, Jandourek A, Friedland HD, Bradley J. A Multicenter, Randomized, Observer-blinded, Active-controlled Study Evaluating the Safety and Effectiveness of Ceftaroline Compared With Ceftriaxone Plus Vancomycin in Pediatric Patients With Complicated Community-acquired Bacterial Pneumonia. Pediatr Infect Dis J. 2016 Jul; 35(7):760-6. PMID: 27078119.
        View in: PubMed
      9. Cannavino CR, Nemeth A, Korczowski B, Bradley J, O'Neal T, Jandourek A, Friedland HD, Kaplan SL. A Randomized, Prospective Study of Pediatric Patients With Community-acquired Pneumonia Treated With Ceftaroline Versus Ceftriaxone. Pediatr Infect Dis J. 2016 Jul; 35(7):752-9. PMID: 27093162.
        View in: PubMed
      10. Cannavino CR, Mendes RE, Sader HS, Farrell DJ, Critchley IA, Biek D, Le J, Skochko SM, Jones RN, Bradley J. Evolution of Ceftaroline-Resistant Mrsa in a Child with Cystic Fibrosis Following Repeated Antibiotic Exposure. Pediatr Infect Dis J. 2016 Jul; 35(7):813-5. PMID: 27093165.
        View in: PubMed
      11. Bradley J, Flanagan SD, Arrieta AC, Jacobs R, Capparelli E, Prokocimer P. Pharmacokinetics, Safety and Tolerability of Single Oral or Intravenous Administration of 200 mg Tedizolid Phosphate in Adolescents. Pediatr Infect Dis J. 2016 Jun; 35(6):628-33. PMID: 26910588.
        View in: PubMed
      12. Bousema T, Stresman G, Baidjoe AY, Bradley J, Knight P, Stone W, Osoti V, Makori E, Owaga C, Odongo W, China P, Shagari S, Doumbo OK, Sauerwein RW, Kariuki S, Drakeley C, Stevenson J, Cox J. The Impact of Hotspot-Targeted Interventions on Malaria Transmission in Rachuonyo South District in the Western Kenyan Highlands: A Cluster-Randomized Controlled Trial. PLoS Med. 2016 Apr; 13(4):e1001993. PMID: 27071072; PMCID: PMC4829260.
      13. Gonzalez D, Palazzi DL, Bhattacharya-Mithal L, Al-Uzri A, James LP, Bradley J, Neu N, Jasion T, Hornik CP, Smith PB, Benjamin DK, Keedy K, Fernandes P, Cohen-Wolkowiez M. Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents. Antimicrob Agents Chemother. 2016 Apr; 60(4):2572-6. PMID: 26883693.
        View in: PubMed
      14. Shoji K, Bradley J, Reed MD, van den Anker JN, Domonoske C, Capparelli EV. Population Pharmacokinetic Assessment and Pharmacodynamic Implications of Pediatric Cefepime Dosing for Susceptible-Dose-Dependent Organisms. Antimicrob Agents Chemother. 2016 Apr; 60(4):2150-6. PMID: 26810655.
        View in: PubMed
      15. Gonçalves BP, Tiono AB, Ouédraogo A, Guelbéogo WM, Bradley J, Nebie I, Siaka D, Lanke K, Eziefula AC, Diarra A, Pett H, Bougouma EC, Sirima SB, Drakeley C, Bousema T. Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebo-controlled trial. BMC Med. 2016; 14:40. PMID: 26952094; PMCID: PMC4782330.
      16. Cannavino CR, Castaneda-Ruiz B, Redman R, Go O, Cirillo I, Barauskas V, Senatorova G, Emeryk A, Bradley J. Safety and Tolerability of Doripenem in Hospitalized Children With Complicated Intra-Abdominal Infection, Complicated Urinary Tract Infections and Pneumonia. Pediatr Infect Dis J. 2015 Nov; 34(11):1264-7. PMID: 26226440.
        View in: PubMed
      17. Arnold JC, Bradley J. Osteoarticular Infections in Children. Infect Dis Clin North Am. 2015 Sep; 29(3):557-74. PMID: 26311358.
        View in: PubMed
      18. Bradley J, Puttagunta S, Rubino CM, Blumer JL, Dunne M, Sullivan JE. Pharmacokinetics, Safety and Tolerability of Single Dose Dalbavancin in Children 12-17 Years of Age. Pediatr Infect Dis J. 2015 Jul; 34(7):748-52. PMID: 25551831.
        View in: PubMed
      19. Le J, Capparelli EV, Wahid U, Wu YS, Romanowski GL, Tran TM, Nguyen A, Bradley J. Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study. Clin Ther. 2015 Jun 1; 37(6):1340-51. PMID: 26031618.
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      20. Cirillo I, Vaccaro N, Castaneda-Ruiz B, Redman R, Cossey V, Bradley J, Allegaert K. Open-Label Study To Evaluate the Single-Dose Pharmacokinetics, Safety, and Tolerability of Doripenem in Infants Less than 12 Weeks in Chronological Age. Antimicrob Agents Chemother. 2015 Aug; 59(8):4742-9. PMID: 26014957.
        View in: PubMed
      21. Olarte L, Barson WJ, Barson RM, Lin PL, Romero JR, Tan TQ, Givner LB, Bradley J, Hoffman JA, Hultén KG, Mason EO, Kaplan SL. Impact of the 13-Valent Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis in US Children. Clin Infect Dis. 2015 Sep 1; 61(5):767-75. PMID: 25972022.
        View in: PubMed
      22. Kaplan SL, Center KJ, Barson WJ, Ling-Lin P, Romero JR, Bradley J, Tan TQ, Hoffman JA, Peters TR, Gurtman A, Scott DA, Trammel J, Gruber WC, Hulten KG, Mason EO. Multicenter Surveillance of Streptococcus pneumoniae Isolates From Middle Ear and Mastoid Cultures in the 13-Valent Pneumococcal Conjugate Vaccine Era. Clin Infect Dis. 2015 May 1; 60(9):1339-45. PMID: 25648240.
        View in: PubMed
      23. Le J, Ny P, Capparelli E, Lane J, Ngu B, Muus R, Romanowski G, Vo T, Bradley J. Pharmacodynamic Characteristics of Nephrotoxicity Associated With Vancomycin Use in Children. J Pediatric Infect Dis Soc. 2015 Dec; 4(4):e109-16. PMID: 26582878.
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      24. Bradley J, Benziger D, Bokesch P, Jacobs R. Single-dose Pharmacokinetics of Daptomycin in Pediatric Patients 3-24 Months of Age. Pediatr Infect Dis J. 2014 Sep; 33(9):936-9. PMID: 25361023.
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      25. Le J, Ngu B, Bradley J, Murray W, Nguyen A, Nguyen L, Romanowski GL, Vo T, Capparelli EV. Vancomycin monitoring in children using bayesian estimation. Ther Drug Monit. 2014 Aug; 36(4):510-8. PMID: 24452067.
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      26. Bradley J, Kauffman RE, Balis DA, Duffy CM, Gerbino PG, Maldonado SD, Noel GJ. Assessment of musculoskeletal toxicity 5 years after therapy with levofloxacin. Pediatrics. 2014 Jul; 134(1):e146-53. PMID: 24918220.
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      27. Bradley J, Peacock G, Krug SE, Bower WA, Cohn AC, Meaney-Delman D, Pavia AT. Pediatric anthrax clinical management. Pediatrics. 2014 May; 133(5):e1411-36. PMID: 24777226.
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      28. Bradley J, Peacock G, Krug SE, Bower WA, Cohn AC, Meaney-Delman D, Pavia AT. Pediatric anthrax clinical management: executive summary. Pediatrics. 2014 May; 133(5):940-2. PMID: 24777221.
        View in: PubMed
      29. Jarvis JN, Bicanic T, Loyse A, Namarika D, Jackson A, Nussbaum JC, Longley N, Muzoora C, Phulusa J, Taseera K, Kanyembe C, Wilson D, Hosseinipour MC, Brouwer AE, Limmathurotsakul D, White N, van der Horst C, Wood R, Meintjes G, Bradley J, Jaffar S, Harrison T. Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes. Clin Infect Dis. 2014 Mar; 58(5):736-45. PMID: 24319084; PMCID: PMC3922213.
      30. Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, Bradley J, Grignard L, Lanke KH, Wanzira H, Mpimbaza A, Nsobya S, White NJ, Webb EL, Staedke SG, Drakeley C. Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis. 2014 Feb; 14(2):130-9. PMID: 24239324.
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      31. Bradley J. Which antibiotic for resistant Gram-positives, and why? J Infect. 2014 Jan; 68 Suppl 1:S63-75. PMID: 24188585.
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      32. Nieves D, Bradley J, Gargas J, Mason WH, Lehman D, Lehman SM, Murray EL, Harriman K, Cherry JD. Exchange blood transfusion in the management of severe pertussis in young infants. Pediatr Infect Dis J. 2013 Jun; 32(6):698-9. PMID: 23407101.
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      33. Boucher HW, Talbot GH, Benjamin DK, Bradley J, Guidos RJ, Jones RN, Murray BE, Bonomo RA, Gilbert D. 10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America. Clin Infect Dis. 2013 Jun; 56(12):1685-94. PMID: 23599308; PMCID: PMC3707426.
      34. Le J, Bradley J, Murray W, Romanowski GL, Tran TT, Nguyen N, Cho S, Natale S, Bui I, Tran TM, Capparelli EV. Improved vancomycin dosing in children using area under the curve exposure. Pediatr Infect Dis J. 2013 Apr; 32(4):e155-63. PMID: 23340565.
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      35. Kaplan SL, Barson WJ, Lin PL, Romero JR, Bradley J, Tan TQ, Hoffman JA, Givner LB, Mason EO. Early trends for invasive pneumococcal infections in children after the introduction of the 13-valent pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2013 Mar; 32(3):203-7. PMID: 23558320.
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      36. Hulten KG, Kaplan SL, Lamberth LB, Barson WJ, Romero JR, Lin PL, Bradley J, Givner LB, Tan TQ, Hoffman JA, Mason EO. Changes in Streptococcus pneumoniae serotype 19A invasive infections in children from 1993 to 2011. J Clin Microbiol. 2013 Apr; 51(4):1294-7. PMID: 23390277.
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      37. Bradley J. Editor's note. Pediatr Infect Dis J. 2013 Feb; 32(2):145. PMID: 23328820.
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      38. Murray EL, Nieves D, Bradley J, Gargas J, Mason WH, Lehman D, Harriman K, Cherry JD. Characteristics of Severe Bordetella pertussis Infection Among Infants =90 Days of Age Admitted to Pediatric Intensive Care Units - Southern California, September 2009-June 2011. J Pediatric Infect Dis Soc. 2013 Mar; 2(1):1-6. PMID: 26619437.
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      39. Tewhey R, Cannavino CR, Leake JA, Bansal V, Topol EJ, Torkamani A, Bradley J, Schork NJ. Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300. BMC Genomics. 2012; 13:508. PMID: 23009684.
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      40. Arnold JC, Cannavino CR, Ross MK, Westley B, Miller TC, Riffenburgh RH, Bradley J. Acute bacterial osteoarticular infections: eight-year analysis of C-reactive protein for oral step-down therapy. Pediatrics. 2012 Oct; 130(4):e821-8. PMID: 22966033.
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      41. Sauberan JB, Bradley J, Blumer J, Stellwagen LM. Transmission of meropenem in breast milk. Pediatr Infect Dis J. 2012 Aug; 31(8):832-4. PMID: 22544050.
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      42. Talbot GH, Powers JH, Fleming TR, Siuciak JA, Bradley J, Boucher H. Progress on developing endpoints for registrational clinical trials of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections: update from the Biomarkers Consortium of the Foundation for the National Institutes of Health. Clin Infect Dis. 2012 Oct; 55(8):1114-21. PMID: 22744885; PMCID: PMC3529608.
      43. Pong A, Moser KS, Park SM, Magit A, Garcia MI, Bradley J. Evaluation of an Interferon Gamma Release Assay to Detect Tuberculosis Infection in Children in San Diego, California. J Pediatric Infect Dis Soc. 2012 Mar; 1(1):74-7. PMID: 26618694.
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      44. Gillis K, Bradley J, Friedlander SF. Persistent subcutaneous nodule: "sealed with a kiss". Pediatr Infect Dis J. 2011 Dec; 30(12):1119, 1126-7. PMID: 22105421.
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      45. Kimberlin DW, Whitley RJ, Wan W, Powell DA, Storch G, Ahmed A, Palmer A, Sánchez PJ, Jacobs RF, Bradley J, Robinson JL, Shelton M, Dennehy PH, Leach C, Rathore M, Abughali N, Wright P, Frenkel LM, Brady RC, Van Dyke R, Weiner LB, Guzman-Cottrill J, McCarthy CA, Griffin J, Jester P, Parker M, Lakeman FD, Kuo H, Lee CH, Cloud GA. Oral acyclovir suppression and neurodevelopment after neonatal herpes. N Engl J Med. 2011 Oct 6; 365(14):1284-92. PMID: 21991950.
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      46. Bradley J, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C, Kaplan SL, Mace SE, McCracken GH, Moore MR, St Peter SD, Stockwell JA, Swanson JT. Executive summary: the management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011 Oct; 53(7):617-30. PMID: 21890766.
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      47. Bradley J, Jackson MA. The use of systemic and topical fluoroquinolones. Pediatrics. 2011 Oct; 128(4):e1034-45. PMID: 21949152.
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      48. Bradley J, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C, Kaplan SL, Mace SE, McCracken GH, Moore MR, St Peter SD, Stockwell JA, Swanson JT. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011 Oct; 53(7):e25-76. PMID: 21880587.
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      49. Abdel-Rahman SM, Chandorkar G, Akins RL, Bradley J, Jacobs RF, Donovan J, Benziger DP. Single-dose pharmacokinetics and tolerability of daptomycin 8 to 10 mg/kg in children aged 2 to 6 years with suspected or proved Gram-positive infections. Pediatr Infect Dis J. 2011 Aug; 30(8):712-4. PMID: 21317681.
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      50. Bradley J, Graham S, Picchio GR, Vugia DJ, Kharrazi M. Prevalence of hepatitis C virus antibody in newborn infants in southern California in 2003. Pediatr Infect Dis J. 2011 Jul; 30(7):618-20. PMID: 21394051.
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      51. Nambiar S, Rellosa N, Wassel RT, Borders-Hemphill V, Bradley J. Linezolid-associated peripheral and optic neuropathy in children. Pediatrics. 2011 Jun; 127(6):e1528-32. PMID: 21555496.
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      52. Combating antimicrobial resistance: policy recommendations to save lives. Clin Infect Dis. 2011 May; 52 Suppl 5:S397-428. PMID: 21474585.
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      53. Green MC, Mason EO, Kaplan SL, Lamberth LB, Stovall SH, Givner LB, Bradley J, Tan TQ, Barson WJ, Hoffman JA, Lin PL, Hulten KG. Increase in prevalence of Streptococcus pneumoniae serotype 6C at Eight Children's Hospitals in the United States from 1993 to 2009. J Clin Microbiol. 2011 Jun; 49(6):2097-101. PMID: 21450963.
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      54. Hernandez JE, Adiga R, Armstrong R, Bazan J, Bonilla H, Bradley J, Dretler R, Ison MG, Mangino JE, Maroushek S, Shetty AK, Wald A, Ziebold C, Elder J, Hollister AS, Sheridan W. Clinical experience in adults and children treated with intravenous peramivir for 2009 influenza A (H1N1) under an Emergency IND program in the United States. Clin Infect Dis. 2011 Mar 15; 52(6):695-706. PMID: 21367722; PMCID: PMC3049340.
      55. Bradley J, Garonzik SM, Forrest A, Bhavnani SM. Pharmacokinetics, pharmacodynamics, and Monte Carlo simulation: selecting the best antimicrobial dose to treat an infection. Pediatr Infect Dis J. 2010 Nov; 29(11):1043-6. PMID: 20975453.
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      56. Bradley J. Considerations unique to pediatrics for clinical trial design in hospital-acquired pneumonia and ventilator-associated pneumonia. Clin Infect Dis. 2010 Aug 1; 51 Suppl 1:S136-43. PMID: 20597664.
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      57. Kimberlin DW, Shalabi M, Abzug MJ, Lang D, Jacobs RF, Storch G, Bradley J, Wade KC, Ramilo O, Romero JR, Shelton M, Leach C, Guzman-Cottrill J, Robinson J, Abughali N, Englund J, Griffin J, Jester P, Cloud GA, Whitley RJ. Safety of oseltamivir compared with the adamantanes in children less than 12 months of age. Pediatr Infect Dis J. 2010 Mar; 29(3):195-8. PMID: 19949363.
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      58. Kaplan SL, Barson WJ, Lin PL, Stovall SH, Bradley J, Tan TQ, Hoffman JA, Givner LB, Mason EO. Serotype 19A Is the most common serotype causing invasive pneumococcal infections in children. Pediatrics. 2010 Mar; 125(3):429-36. PMID: 20176669.
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      59. Bratincsák A, El-Said HG, Bradley J, Shayan K, Grossfeld PD, Cannavino CR. Fulminant myocarditis associated with pandemic H1N1 influenza A virus in children. J Am Coll Cardiol. 2010 Mar 2; 55(9):928-9. PMID: 20153131.
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      60. Solomkin JS, Mazuski JE, Bradley J, Rodvold KA, Goldstein EJ, Baron EJ, O'Neill PJ, Chow AW, Dellinger EP, Eachempati SR, Gorbach S, Hilfiker M, May AK, Nathens AB, Sawyer RG, Bartlett JG. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect (Larchmt). 2010 Feb; 11(1):79-109. PMID: 20163262.
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      61. Solomkin JS, Mazuski JE, Bradley J, Rodvold KA, Goldstein EJ, Baron EJ, O'Neill PJ, Chow AW, Dellinger EP, Eachempati SR, Gorbach S, Hilfiker M, May AK, Nathens AB, Sawyer RG, Bartlett JG. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis. 2010 Jan 15; 50(2):133-64. PMID: 20034345.
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      62. Kimberlin DW, Jacobs RF, Weller S, van der Walt JS, Heitman CK, Man CY, Bradley J. Pharmacokinetics and safety of extemporaneously compounded valacyclovir oral suspension in pediatric patients from 1 month through 11 years of age. Clin Infect Dis. 2010 Jan 15; 50(2):221-8. PMID: 20014952.
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      63. Ballock RT, Newton PO, Evans SJ, Estabrook M, Farnsworth CL, Bradley J. A comparison of early versus late conversion from intravenous to oral therapy in the treatment of septic arthritis. J Pediatr Orthop. 2009 Sep; 29(6):636-42. PMID: 19700997.
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      64. Spellberg B, Talbot GH, Boucher HW, Bradley J, Gilbert D, Scheld WM, Edwards J, Bartlett JG. Antimicrobial agents for complicated skin and skin-structure infections: justification of noninferiority margins in the absence of placebo-controlled trials. Clin Infect Dis. 2009 Aug 1; 49(3):383-91. PMID: 19555285.
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      65. Bradley J. What is the appropriate treatment course for bacterial arthritis in children? Clin Infect Dis. 2009 May 1; 48(9):1211-2. PMID: 19323629.
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      66. Harper SA, Bradley J, Englund JA, File TM, Gravenstein S, Hayden FG, McGeer AJ, Neuzil KM, Pavia AT, Tapper ML, Uyeki TM, Zimmerman RK. Seasonal influenza in adults and children--diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis. 2009 Apr 15; 48(8):1003-32. PMID: 19281331.
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      67. Bradley J, Wassel RT, Lee L, Nambiar S. Intravenous ceftriaxone and calcium in the neonate: assessing the risk for cardiopulmonary adverse events. Pediatrics. 2009 Apr; 123(4):e609-13. PMID: 19289450.
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      68. Zaoutis TE, Jafri HS, Huang LM, Locatelli F, Barzilai A, Ebell W, Steinbach WJ, Bradley J, Lieberman JM, Hsiao CC, Seibel N, Laws HJ, Gamba M, Petrecz M, Taylor AF, Strohmaier KM, Chow JW, Kartsonis NA, Ngai AL. A prospective, multicenter study of caspofungin for the treatment of documented Candida or Aspergillus infections in pediatric patients. Pediatrics. 2009 Mar; 123(3):877-84. PMID: 19255017.
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      69. Boucher HW, Talbot GH, Bradley J, Edwards JE, Gilbert D, Rice LB, Scheld M, Spellberg B, Bartlett J. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis. 2009 Jan 1; 48(1):1-12. PMID: 19035777.
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      70. Bradley J, McCracken GH. Unique considerations in the evaluation of antibacterials in clinical trials for pediatric community-acquired pneumonia. Clin Infect Dis. 2008 Dec 1; 47 Suppl 3:S241-8. PMID: 18986297.
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      71. Spellberg B, Talbot GH, Brass EP, Bradley J, Boucher HW, Gilbert DN. Position paper: recommended design features of future clinical trials of antibacterial agents for community-acquired pneumonia. Clin Infect Dis. 2008 Dec 1; 47 Suppl 3:S249-65. PMID: 19018610.
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      72. Bradley J, Sauberan JB, Ambrose PG, Bhavnani SM, Rasmussen MR, Capparelli EV. Meropenem pharmacokinetics, pharmacodynamics, and Monte Carlo simulation in the neonate. Pediatr Infect Dis J. 2008 Sep; 27(9):794-9. PMID: 18645546.
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      73. James HE, Bradley J. Management of complicated shunt infections: a clinical report. J Neurosurg Pediatr. 2008 Mar; 1(3):223-8. PMID: 18352767.
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      74. James HE, Bradley J. Aggressive management of shunt infection: combined intravenous and intraventricular antibiotic therapy for twelve or less days. Pediatr Neurosurg. 2008; 44(2):104-11. PMID: 18230923.
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      75. Spellberg B, Guidos R, Gilbert D, Bradley J, Boucher HW, Scheld WM, Bartlett JG, Edwards J. The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America. Clin Infect Dis. 2008 Jan 15; 46(2):155-64. PMID: 18171244.
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      76. Bradley J, Arguedas A, Blumer JL, Sáez-Llorens X, Melkote R, Noel GJ. Comparative study of levofloxacin in the treatment of children with community-acquired pneumonia. Pediatr Infect Dis J. 2007 Oct; 26(10):868-78. PMID: 17901791.
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      77. Noel GJ, Bradley J, Kauffman RE, Duffy CM, Gerbino PG, Arguedas A, Bagchi P, Balis DA, Blumer JL. Comparative safety profile of levofloxacin in 2523 children with a focus on four specific musculoskeletal disorders. Pediatr Infect Dis J. 2007 Oct; 26(10):879-91. PMID: 17901792.
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      78. Bradley J. Antibiotic stewardship in pediatrics: a necessity. Pediatr Infect Dis J. 2007 Jun; 26(6):538-9. PMID: 17529874.
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      79. Mason EO, Wald ER, Tan TQ, Schutze GE, Bradley J, Barson WJ, Givner LB, Hoffman J, Kaplan SL. Recurrent systemic pneumococcal disease in children. Pediatr Infect Dis J. 2007 Jun; 26(6):480-4. PMID: 17529863.
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      80. Abdel-Rahman SM, Jacobs RF, Massarella J, Kauffman RE, Bradley J, Kimko HC, Kearns GL, Shalayda K, Curtin C, Maldonado SD, Blumer JL. Single-dose pharmacokinetics of intravenous itraconazole and hydroxypropyl-beta-cyclodextrin in infants, children, and adolescents. Antimicrob Agents Chemother. 2007 Aug; 51(8):2668-73. PMID: 17517842.
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      81. Amyes SG, Walsh FM, Bradley J. Best in class: a good principle for antibiotic usage to limit resistance development? J Antimicrob Chemother. 2007 May; 59(5):825-6. PMID: 17395687.
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      82. Barr CE, Schulman K, Iacuzio D, Bradley J. Effect of oseltamivir on the risk of pneumonia and use of health care services in children with clinically diagnosed influenza. Curr Med Res Opin. 2007 Mar; 23(3):523-31. PMID: 17355734.
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      83. Rubino CM, Capparelli EV, Bradley J, Blumer JL, Kearns GL, Reed M, Jacobs RF, Cirincione B, Grasela DM. Population pharmacokinetic model for gatifloxacin in pediatric patients. Antimicrob Agents Chemother. 2007 Apr; 51(4):1246-52. PMID: 17220409.
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      84. Bradley J, Guidos R, Baragona S, Bartlett JG, Rubinstein E, Zhanel GG, Tino MD, Pompliano DL, Tally F, Tipirneni P, Tillotson GS, Powers JH, Tillotson GS. Anti-infective research and development--problems, challenges, and solutions. Lancet Infect Dis. 2007 Jan; 7(1):68-78. PMID: 17182346.
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      85. Rubino CM, Bradley J. Optimizing therapy with antibacterial agents: use of pharmacokinetic-pharmacodynamic principles in pediatrics. Paediatr Drugs. 2007; 9(6):361-9. PMID: 18052406.
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      86. Dehority W, Wang E, Vernon PS, Lee C, Perdreau-Remington F, Bradley J. Community-associated methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a neonate. Pediatr Infect Dis J. 2006 Nov; 25(11):1080-1. PMID: 17072137.
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      87. Green MD, Beall B, Marcon MJ, Allen CH, Bradley J, Dashefsky B, Gilsdorf JR, Schutze GE, Smith C, Walter EB, Martin JM, Edwards KM, Barbadora KA, Wald ER. Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA. J Antimicrob Chemother. 2006 Jun; 57(6):1240-3. PMID: 16556634.
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      88. Bradley J. New antibiotics for Gram-positive infections. Adv Exp Med Biol. 2006; 582:151-65. PMID: 16802626.
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      89. Bradley J. Pharmacodynamics and the prediction of efficacy in short-course antibiotic therapy: pediatric studies to validate the model. Pharmacotherapy. 2005 Dec; 25(12 Pt 2):159S-164S. PMID: 16305287.
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      90. Capparelli E, Hochwald C, Rasmussen M, Parham A, Bradley J, Moya F. Population pharmacokinetics of cefepime in the neonate. Antimicrob Agents Chemother. 2005 Jul; 49(7):2760-6. PMID: 15980347.
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      91. Pong AL, Bradley J. Guidelines for the selection of antibacterial therapy in children. Pediatr Clin North Am. 2005 Jun; 52(3):869-94, viii. PMID: 15925666.
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      92. Green M, Allen C, Bradley J, Dashefsky B, Gilsdorf JR, Marcon MJ, Schutze GE, Smith C, Walter E, Martin JM, Edwards KA, Barbadora KA, Rumbaugh RM, Wald ER. In vitro activity of telithromycin against macrolide-susceptible and macrolide-resistant pharyngeal isolates of group A streptococci in the United States. Antimicrob Agents Chemother. 2005 Jun; 49(6):2487-9. PMID: 15917551; PMCID: PMC1140514.
      93. McEllistrem MC, Adams JM, Patel K, Mendelsohn AB, Kaplan SL, Bradley J, Schutze GE, Kim KS, Mason EO, Wald ER. Acute otitis media due to penicillin-nonsusceptible Streptococcus pneumoniae before and after the introduction of the pneumococcal conjugate vaccine. Clin Infect Dis. 2005 Jun 15; 40(12):1738-44. PMID: 15909260.
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      94. Langley JM, Bradley J. Defining pneumonia in critically ill infants and children. Pediatr Crit Care Med. 2005 May; 6(3 Suppl):S9-S13. PMID: 15857566.
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      95. Capparelli EV, Reed MD, Bradley J, Kearns GL, Jacobs RF, Damle BD, Blumer JL, Grasela DM. Pharmacokinetics of gatifloxacin in infants and children. Antimicrob Agents Chemother. 2005 Mar; 49(3):1106-12. PMID: 15728910.
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      96. Saitoh A, Pong A, Waecker NJ, Leake JA, Nespeca MP, Bradley J. Prediction of neurologic sequelae in childhood tuberculous meningitis: a review of 20 cases and proposal of a novel scoring system. Pediatr Infect Dis J. 2005 Mar; 24(3):207-12. PMID: 15750455.
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      97. Chien S, Wells TG, Blumer JL, Kearns GL, Bradley J, Bocchini JA, Natarajan J, Maldonado S, Noel GJ. Levofloxacin pharmacokinetics in children. J Clin Pharmacol. 2005 Feb; 45(2):153-60. PMID: 15647407.
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      98. Bradley J. Newer antistaphylococcal agents. Curr Opin Pediatr. 2005 Feb; 17(1):71-7. PMID: 15659968.
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      99. Talbot GH, Bradley J, Edwards JE, Gilbert D, Scheld M, Bartlett JG. Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis. 2006 Mar 1; 42(5):657-68. PMID: 16447111.
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      100. Leake JA, Albani S, Kao AS, Senac MO, Billman GF, Nespeca MP, Paulino AD, Quintela ER, Sawyer MH, Bradley J. Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features. Pediatr Infect Dis J. 2004 Aug; 23(8):756-64. PMID: 15295226.
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      101. Tice AD, Rehm SJ, Dalovisio JR, Bradley J, Martinelli LP, Graham DR, Gainer RB, Kunkel MJ, Yancey RW, Williams DN. Practice guidelines for outpatient parenteral antimicrobial therapy. IDSA guidelines. Clin Infect Dis. 2004 Jun 15; 38(12):1651-72. PMID: 15227610.
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      102. Givner LB, Mason EO, Tan TQ, Barson WJ, Schutze GE, Wald ER, Bradley J, Hoffman J, Yogev R, Kaplan SL. Pneumococcal endocarditis in children. Clin Infect Dis. 2004 May 1; 38(9):1273-8. PMID: 15127340.
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      103. Kaplan SL, Mason EO, Wald ER, Schutze GE, Bradley J, Tan TQ, Hoffman JA, Givner LB, Yogev R, Barson WJ. Decrease of invasive pneumococcal infections in children among 8 children's hospitals in the United States after the introduction of the 7-valent pneumococcal conjugate vaccine. Pediatrics. 2004 Mar; 113(3 Pt 1):443-9. PMID: 14993532.
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      104. Pong A, Bradley J. Clinical challenges of nosocomial infections caused by antibiotic-resistant pathogens in pediatrics. Semin Pediatr Infect Dis. 2004 Jan; 15(1):21-9. PMID: 15175992.
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      105. Hoffman JA, Mason EO, Schutze GE, Tan TQ, Barson WJ, Givner LB, Wald ER, Bradley J, Yogev R, Kaplan SL. Streptococcus pneumoniae infections in the neonate. Pediatrics. 2003 Nov; 112(5):1095-102. PMID: 14595052.
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      106. Bradley J, Dudley MN, Drusano GL. Predicting efficacy of antiinfectives with pharmacodynamics and Monte Carlo simulation. Pediatr Infect Dis J. 2003 Nov; 22(11):982-92; quiz 993-5. PMID: 14614372.
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      107. Mason EO, Wald ER, Bradley J, Barson WJ, Kaplan SL. Macrolide resistance among middle ear isolates of Streptococcus pneumoniae observed at eight United States pediatric centers: prevalence of M and MLSB phenotypes. Pediatr Infect Dis J. 2003 Jul; 22(7):623-7. PMID: 12867838.
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      108. McAleer IM, Kaplan GW, Bradley J, Carroll SF, Griffith DP. Endotoxin content in renal calculi. J Urol. 2003 May; 169(5):1813-4. PMID: 12686850.
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      109. Abzug MJ, Cloud G, Bradley J, Sánchez PJ, Romero J, Powell D, Lepow M, Mani C, Capparelli EV, Blount S, Lakeman F, Whitley RJ, Kimberlin DW. Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. Pediatr Infect Dis J. 2003 Apr; 22(4):335-41. PMID: 12690273.
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      110. Mason EO, Lamberth LB, Wald ER, Bradley J, Barson WJ, Kaplan SL. In vitro activities of cethromycin (ABT-773), a new ketolide, against Streptococcus pneumoniae strains that are not susceptible to penicillin or macrolides. Antimicrob Agents Chemother. 2003 Jan; 47(1):166-9. PMID: 12499186.
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      111. Tan TQ, Mason EO, Wald ER, Barson WJ, Schutze GE, Bradley J, Givner LB, Yogev R, Kim KS, Kaplan SL. Clinical characteristics of children with complicated pneumonia caused by Streptococcus pneumoniae. Pediatrics. 2002 Jul; 110(1 Pt 1):1-6. PMID: 12093940.
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      112. Bradley J. Management of community-acquired pediatric pneumonia in an era of increasing antibiotic resistance and conjugate vaccines. Pediatr Infect Dis J. 2002 Jun; 21(6):592-8; discussion 613-4. PMID: 12182396.
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      113. Schutze GE, Mason EO, Barson WJ, Kim KS, Wald ER, Givner LB, Tan TQ, Bradley J, Yogev R, Kaplan SL. Invasive pneumococcal infections in children with asplenia. Pediatr Infect Dis J. 2002 Apr; 21(4):278-82. PMID: 12075756.
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      114. McAleer IM, Kaplan GW, Bradley J, Carroll SF. Staghorn calculus endotoxin expression in sepsis. Urology. 2002 Apr; 59(4):601. PMID: 11927328.
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      115. Bradley J. Old and new antibiotics for pediatric pneumonia. Semin Respir Infect. 2002 Mar; 17(1):57-64. PMID: 11891519.
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      116. Kaplan SL, Mason EO, Wald E, Tan TQ, Schutze GE, Bradley J, Givner LB, Kim KS, Yogev R, Barson WJ. Six year multicenter surveillance of invasive pneumococcal infections in children. Pediatr Infect Dis J. 2002 Feb; 21(2):141-7. PMID: 11840082.
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      117. Leake JA, Billman GF, Nespeca MP, Duthie SE, Dory CE, Meltzer HS, Bradley J. Pediatric acute hemorrhagic leukoencephalitis: report of a surviving patient and review. Clin Infect Dis. 2002 Mar 1; 34(5):699-703. PMID: 11810602.
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      118. Sáez-Llorens X, McCoig C, Feris JM, Vargas SL, Klugman KP, Hussey GD, Frenck RW, Falleiros-Carvalho LH, Arguedas AG, Bradley J, Arrieta AC, Wald ER, Pancorbo S, McCracken GH, Marques SR. Quinolone treatment for pediatric bacterial meningitis: a comparative study of trovafloxacin and ceftriaxone with or without vancomycin. Pediatr Infect Dis J. 2002 Jan; 21(1):14-22. PMID: 11791092.
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