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    Johannes Schlachetzki

    TitlePostdoctoral Scholar
    SchoolUniversity of California, San Diego
    DepartmentCellular and Molecular Medicine
    Address9500 Gilman Drive #0651
    CA La Jolla 92093
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Frentzel D, Judanin G, Borozdina O, Klucken J, Winkler J, Schlachetzki J. Increase of Reproductive Life Span Delays Age of Onset of Parkinson's Disease. Front Neurol. 2017; 8:397. PMID: 28871235.
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      2. Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki J, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. An environment-dependent transcriptional network specifies human microglia identity. Science. 2017 Jun 23; 356(6344). PMID: 28546318.
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      3. Kohl Z, Schlachetzki J, Feldewerth J, Hornauer P, Münch M, Adame A, Riemenschneider MJ, Winkler J, Masliah E. Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies. Neural Plast. 2017; 2017:3851262. PMID: 28409032.
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      4. Lee DH, Seubert S, Huhn K, Brecht L, Rötger C, Waschbisch A, Schlachetzki J, Klausmeyer A, Melms A, Wiese S, Winkler J, Linker RA. Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters? PLoS One. 2017; 12(3):e0171552. PMID: 28273090.
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      5. Hoffmann A, Ettle B, Bruno A, Kulinich A, Hoffmann AC, von Wittgenstein J, Winkler J, Xiang W, Schlachetzki J. Alpha-synuclein activates BV2 microglia dependent on its aggregation state. Biochem Biophys Res Commun. 2016 Oct 28; 479(4):881-886. PMID: 27666480.
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      6. Distler M, Schlachetzki J, Kohl Z, Winkler J, Schenk T. Paradoxical kinesia in Parkinson's disease revisited: Anticipation of temporal constraints is critical. Neuropsychologia. 2016 Jun; 86:38-44. PMID: 27090103.
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      7. Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki J, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. a-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathol. 2016 Jul; 132(1):59-75. PMID: 27059609; PMCID: PMC4912450 [Available on 07/01/17].
      8. Salvi R, Steigleder T, Schlachetzki J, Waldmann E, Schwab S, Winner B, Winkler J, Kohl Z. Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice. Front Neurosci. 2016; 10:77. PMID: 27013940; PMCID: PMC4786557.
      9. Schlachetzki J, Grimm T, Schlachetzki Z, Ben Abdallah NM, Ettle B, Vöhringer P, Ferger B, Winner B, Nuber S, Winkler J. Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of a-synuclein. J Neurosci Res. 2016 Jan; 94(1):62-73. PMID: 26451750.
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      10. Mrochen A, Marxreiter F, Kohl Z, Schlachetzki J, Renner B, Schenk T, Winkler J, Klucken J. From sweet to sweat: Hedonic olfactory range is impaired in Parkinson's disease. Parkinsonism Relat Disord. 2016 Jan; 22:9-14. PMID: 26627940.
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      11. Süß P, Kalinichenko L, Baum W, Reichel M, Kornhuber J, Loskarn S, Ettle B, Distler JH, Schett G, Winkler J, Müller CP, Schlachetzki J. Hippocampal structure and function are maintained despite severe innate peripheral inflammation. Brain Behav Immun. 2015 Oct; 49:156-70. PMID: 26074461.
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      12. Ettle B, Schlachetzki J, Winkler J. Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders? Mol Neurobiol. 2016 Jul; 53(5):3046-3062. PMID: 25966971; PMCID: PMC4902834.
      13. Schlachetzki J, Winkler J. The innate immune system in Parkinson's disease: a novel target promoting endogenous neuroregeneration. Neural Regen Res. 2015 May; 10(5):704-6. PMID: 26109939; PMCID: PMC4468756.
      14. Xiang W, Menges S, Schlachetzki J, Meixner H, Hoffmann AC, Schlötzer-Schrehardt U, Becker CM, Winkler J, Klucken J. Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity. Mol Neurodegener. 2015 Mar 11; 10:8. PMID: 25886189; PMCID: PMC4365527.
      15. Ettle B, Reiprich S, Deusser J, Schlachetzki J, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J. Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells. Mol Cell Neurosci. 2014 Sep; 62:68-78. PMID: 25019582; PMCID: PMC4170075.
      16. Schlachetzki J, Pizzo DP, Morrissette DA, Winkler J. Intracerebroventricular administration of nerve growth factor induces gliogenesis in sensory ganglia, dorsal root, and within the dorsal root entry zone. Biomed Res Int. 2014; 2014:704259. PMID: 24738070; PMCID: PMC3971563.
      17. Schlachetzki J, Marxreiter F, Regensburger M, Kulinich A, Winner B, Winkler J. Increased tyrosine hydroxylase expression accompanied by glial changes within the non-lesioned hemisphere in the 6-hydroxydopamine model of Parkinson's disease. Restor Neurol Neurosci. 2014; 32(4):447-62. PMID: 24604006.
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      18. Kallmünzer B, Tauchi M, Schlachetzki J, Machold K, Schmidt A, Winkler J, Schwab S, Kollmar R. Granulocyte colony-stimulating factor does not promote neurogenesis after experimental intracerebral haemorrhage. Int J Stroke. 2014 Aug; 9(6):783-8. PMID: 24920160.
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      19. Klucken J, Barth J, Kugler P, Schlachetzki J, Henze T, Marxreiter F, Kohl Z, Steidl R, Hornegger J, Eskofier B, Winkler J. Unbiased and mobile gait analysis detects motor impairment in Parkinson's disease. PLoS One. 2013; 8(2):e56956. PMID: 23431395; PMCID: PMC3576377.
      20. Xiang W, Schlachetzki J, Helling S, Bussmann JC, Berlinghof M, Schäffer TE, Marcus K, Winkler J, Klucken J, Becker CM. Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity. Mol Cell Neurosci. 2013 May; 54:71-83. PMID: 23369945.
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      21. Schlachetzki J, Saliba SW, Oliveira AC. Studying neurodegenerative diseases in culture models. Rev Bras Psiquiatr. 2013; 35 Suppl 2:S92-100. PMID: 24271231.
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