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    Jean Lewis

    TitleAssistant Project Scientist
    SchoolUniversity of California, San Diego
    DepartmentNanoengineering
    Address9500 Gilman Drive #0448
    CA La Jolla 92093
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      Collapse Biography 
      Collapse Education and Training
      Bryn Mawr/Haverford College, Philadelphia,PAABMolecular Biology
      Scripps Research Institute, La Jolla, CA08/1994Post-doctoral Fellow
      University of Pennsylvania, Philadelphia, PAPh.D.12/1990Biochemistry

      Collapse Overview 

      Collapse Research 
      Collapse Research Activities and Funding
      C ABL TYROSINE KINASE IN INTEGRIN DEPENDENT SIGNALING
      NIH/NCI R29CA074230Dec 5, 1997 - Nov 30, 2002
      Role: Principal Investigator
      SIGNAL TRANSUCTION BY INTEGRINS
      NIH/NIGMS F32GM016000Mar 21, 1995
      Role: Principal Investigator
      Signal Transduction by Integrins
      Elsa U. Pardee Cancer Foundation

      Collapse ORNG Applications 
      Collapse Featured Publications

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Ibsen SD, Wright J, Lewis J, Kim S, Ko SY, Ong J, Manouchehri S, Vyas A, Akers J, Chen CC, Carter BS, Esener SC, Heller MJ. Rapid Isolation and Detection of Exosomes and Associated Biomarkers from Plasma. ACS Nano. 2017 Jul 25; 11(7):6641-6651. PMID: 28671449.
        View in: PubMed
      2. Heineck DP, Lewis J, Heller MJ. Electrokinetic device design and constraints for use in high conductance solutions. Electrophoresis. 2017 Jun; 38(11):1475-1482. PMID: 28401635.
        View in: PubMed
      3. Lewis J, Heineck DP, Heller MJ. Detecting cancer biomarkers in blood: challenges for new molecular diagnostic and point-of-care tests using cell-free nucleic acids. Expert Rev Mol Diagn. 2015; 15(9):1187-200. PMID: 26189641.
        View in: PubMed
      4. Lewis J, Truong TN, Schwartz MA. Integrins regulate the apoptotic response to DNA damage through modulation of p53. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3627-32. PMID: 11904424; PMCID: PMC122574.
      5. Renshaw MW, Lewis J, Schwartz MA. The c-Abl tyrosine kinase contributes to the transient activation of MAP kinase in cells plated on fibronectin. Oncogene. 2000 Jun 29; 19(28):3216-9. PMID: 10918577.
        View in: PubMed
      6. Lewis J, Schwartz MA. Integrins regulate the association and phosphorylation of paxillin by c-Abl. J Biol Chem. 1998 Jun 05; 273(23):14225-30. PMID: 9603926.
        View in: PubMed
      7. Brooks PC, Klemke RL, Schon S, Lewis J, Schwartz MA, Cheresh DA. Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo. J Clin Invest. 1997 Mar 15; 99(6):1390-8. PMID: 9077549; PMCID: PMC507955.
      8. Lewis J, Baskaran R, Taagepera S, Schwartz MA, Wang JY. Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport. Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15174-9. PMID: 8986783; PMCID: PMC26376.
      9. Lewis J, Cheresh DA, Schwartz MA. Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. J Cell Biol. 1996 Sep; 134(5):1323-32. PMID: 8794871; PMCID: PMC2120976.
      10. Meredith JE, Winitz S, Lewis J, Hess S, Ren XD, Renshaw MW, Schwartz MA. The regulation of growth and intracellular signaling by integrins. Endocr Rev. 1996 Jun; 17(3):207-20. PMID: 8771356.
        View in: PubMed
      11. Lewis J, Schwartz MA. Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants. Mol Biol Cell. 1995 Feb; 6(2):151-60. PMID: 7540435; PMCID: PMC275825.
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