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    David Gorkin

    TitleSpecialist
    SchoolUniversity of California, San Diego
    DepartmentCellular and Molecular Medicine
    Address9500 Gilman Drive #0767
    CA La Jolla 92093
    Phone858-534-7581
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. He Y, Gorkin D, Dickel DE, Nery JR, Castanon RG, Lee AY, Shen Y, Visel A, Pennacchio LA, Ren B, Ecker JR. Improved regulatory element prediction based on tissue-specific local epigenomic signatures. Proc Natl Acad Sci U S A. 2017 Feb 28; 114(9):E1633-E1640. PMID: 28193886.
        View in: PubMed
      2. Dickel DE, Barozzi I, Zhu Y, Fukuda-Yuzawa Y, Osterwalder M, Mannion BJ, May D, Spurrell CH, Plajzer-Frick I, Pickle CS, Lee E, Garvin TH, Kato M, Akiyama JA, Afzal V, Lee AY, Gorkin D, Ren B, Rubin EM, Visel A, Pennacchio LA. Genome-wide compendium and functional assessment of in vivo heart enhancers. Nat Commun. 2016 Oct 05; 7:12923. PMID: 27703156.
        View in: PubMed
      3. Dixon JR, Gorkin D, Ren B. Chromatin Domains: The Unit of Chromosome Organization. Mol Cell. 2016 Jun 02; 62(5):668-80. PMID: 27259200.
        View in: PubMed
      4. Fufa TD, Harris ML, Watkins-Chow DE, Levy D, Gorkin D, Gildea DE, Song L, Safi A, Crawford GE, Sviderskaya EV, Bennett DC, Mccallion AS, Loftus SK, Pavan WJ. Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes. Hum Mol Genet. 2015 Oct 01; 24(19):5433-50. PMID: 26206884; PMCID: PMC4572067 [Available on 10/01/16].
      5. Lee D, Gorkin D, Baker M, Strober BJ, Asoni AL, McCallion AS, Beer MA. A method to predict the impact of regulatory variants from DNA sequence. Nat Genet. 2015 Aug; 47(8):955-61. PMID: 26075791; PMCID: PMC4520745.
      6. Gorkin D, Leung D, Ren B. The 3D genome in transcriptional regulation and pluripotency. Cell Stem Cell. 2014 Jun 05; 14(6):762-75. PMID: 24905166; PMCID: PMC4107214.
      7. Gorkin D, Ren B. Genetics: Closing the distance on obesity culprits. Nature. 2014 Mar 20; 507(7492):309-10. PMID: 24646989.
        View in: PubMed
      8. Praetorius C, Grill C, Stacey SN, Metcalf AM, Gorkin D, Robinson KC, Van Otterloo E, Kim RS, Bergsteinsdottir K, Ogmundsdottir MH, Magnusdottir E, Mishra PJ, Davis SR, Guo T, Zaidi MR, Helgason AS, Sigurdsson MI, Meltzer PS, Merlino G, Petit V, Larue L, Loftus SK, Adams DR, Sobhiafshar U, Emre NC, Pavan WJ, Cornell R, Smith AG, McCallion AS, Fisher DE, Stefansson K, Sturm RA, Steingrimsson E. A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell. 2013 Nov 21; 155(5):1022-33. PMID: 24267888; PMCID: PMC3873608.
      9. Gorkin D, Lee D, Reed X, Fletez-Brant C, Bessling SL, Loftus SK, Beer MA, Pavan WJ, McCallion AS. Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes. Genome Res. 2012 Nov; 22(11):2290-301. PMID: 23019145; PMCID: PMC3483558.
      10. Prasad MK, Reed X, Gorkin D, Cronin JC, McAdow AR, Chain K, Hodonsky CJ, Jones EA, Svaren J, Antonellis A, Johnson SL, Loftus SK, Pavan WJ, McCallion AS. SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer. BMC Dev Biol. 2011 Jun 14; 11:40. PMID: 21672228; PMCID: PMC3124416.
      11. Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, Buckhaults PJ, Park BH. Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations. Oncogene. 2010 Apr 22; 29(16):2337-45. PMID: 20101210; PMCID: PMC3042798.
      12. Stine ZE, Huynh JL, Loftus SK, Gorkin D, Salmasi AH, Novak T, Purves T, Miller RA, Antonellis A, Gearhart JP, Pavan WJ, McCallion AS. Oligodendroglial and pan-neural crest expression of Cre recombinase directed by Sox10 enhancer. Genesis. 2009 Nov; 47(11):765-70. PMID: 19830815; PMCID: PMC2835405.
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