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Daniel Kripke
Title
Senate Emeritus
School
University of California, San Diego
Department
Psychiatry
Address
9500 Gilman Drive #0603
CA La Jolla 92093
Phone
858-222-2934
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Overview
Overview
Biography
Educated at Harvard College, P&S, the US Air Force 6571st Aeromedical Research Lab and an Albert Einstein residency, Dr. Kripke has spent over 30 years at UCSD. He developed the first sleep clinic in the region and new technologies for home sleep monitoring and wrist actigraphy. He did the first controlled trial of bright light treatment at the San Diego VA Medical Center in 1981. He has been concerned with the community prevalence of sleep apnea, particularly with aging, and the excess mortality associated with sleep >= 8 hours and with sleeping pills. With development of the Circadian Pacemaker Laboratory in the Sam and Rose Stein Clinical Research Building, they have been doing studies in basic and applied human chronobiology with a view towards understanding affective disorders.
Research Interests
Current studies focus on bright light treatment of depression, the clinical efficacy and the underlying mechanisms. They are also interested in the circadian phase-response to bright light and exercise stimuli and the consequences for melatonin regulation. Light’s roll in photoperiodic regulation in humans is a long-term theme. Preliminary studies are examining how genetic variations in circadian clocks may influence clinical pathology.
Research
Research Activities and Funding
Light Stimulation of Luteinizing Hormone
NIH/NIMH
R01MH068545
Sep 1, 2004 - Aug 31, 2008
Role: Principal Investigator
GENETIC VARIANTS IN CIRCADIAN RHYTHM SLEEP DISORDERS
NIH/NHLBI
R01HL071123
Apr 1, 2004 - Jun 30, 2007
Role: Principal Investigator
GENETIC VARIANTS IN CIRCADIAN RHYTHM SLEEP DISORDERS
NIH/NHLBI
R56HL071123
Jul 1, 2002 - Jun 30, 2009
Role: Principal Investigator
PHASE RESPONSE CURVES FOR EXERCISE AND BRIGHT LIGHT
NIH/NHLBI
R01HL061280
Aug 1, 1999 - Jul 31, 2004
Role: Principal Investigator
VERIFICATION OF CIRCADIAN ABNORMALITIES IN AGING
NIH/NIA
R01AG015763
Sep 1, 1998 - Aug 31, 2004
Role: Principal Investigator
EMF EFFECTS ON MELATONIN AMONG AGING VOLUNTEERS
NIH/NIEHS
R03ES008930
Jan 15, 1997 - Jun 30, 1999
Role: Principal Investigator
VALIDATION AND EXPLORATION OF SLEEP AND MOOD PREDICTORS
NIH/NHLBI
R01HL055983
Aug 1, 1995 - Jul 31, 2000
Role: Principal Investigator
ILLUMINATION IN HUMAN AGING: SLEEP AND MOOD EFFECTS
NIH/NIA
R01AG012364
Sep 30, 1994 - Apr 30, 2006
Role: Principal Investigator
BEHAVIORAL/LIGHT EFFECTS ON MENSTRUAL CYCLE REGULATION
NIH/NIMH
R03MH051820
May 1, 1994 - Apr 30, 1997
Role: Principal Investigator
AGE RELATED PREVALENCE OF SLEEP RESPIRATORY DISTURBANCES
NIH/NHLBI
R01HL040930
Apr 1, 1990 - Mar 31, 1996
Role: Principal Investigator
PHOTOPERIODIC TREATMENT OF DEPRESSION
NIH/NIMH
R01MH038822
Mar 1, 1984 - Jun 30, 1988
Role: Principal Investigator
PREVALENCE OF SLEEP APNEA IN AN AGED POPULATION
NIH/NIA
R01AG002711
Apr 1, 1981 - Mar 31, 2001
Role: Co-Principal Investigator
BIO-OSCILLATOR EFFECTS ON MENTAL FUNCTION
NIH/NIMH
K05MH000117
Jan 1, 1977 - Dec 31, 1996
Role: Principal Investigator
BIO-OSCILLATOR EFFECTS ON MENTAL FUNCTION
NIH/NIMH
K02MH000117
Jan 1, 1977 - Dec 31, 1986
Role: Principal Investigator
Bibliographic
Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can
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Kripke D
. What do hypnotics cost hospitals and healthcare? F1000Res. 2017; 6:542. PMID: 28781755.
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PubMed
Moon JH, Cho CH, Son GH, Geum D, Chung S, Kim H, Kang SG, Park YM, Yoon HK, Kim L, Jee HJ, An H,
Kripke D
, Lee HJ. Advanced Circadian Phase in Mania and Delayed Circadian Phase in Mixed Mania and Depression Returned to Normal after Treatment of Bipolar Disorder. EBioMedicine. 2016 Sep; 11:285-295. PMID: 27543154.
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PubMed
Kripke D
. Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit. F1000Res. 2016; 5:918. PMID: 27303633; PMCID: PMC4890308.
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Kripke D
. When our body clocks run late: does it make us depressed? Ann Transl Med. 2016 May; 4(9):178. PMID: 27275491; PMCID: PMC4876263.
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PubMed Central
Kripke D
. Mortality Risk of Hypnotics: Strengths and Limits of Evidence. Drug Saf. 2016 Feb; 39(2):93-107. PMID: 26563222.
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PubMed
Kripke D
. I petitioned the FDA to restrict hypnotics: here is why. Sleep Med. 2016 Jul; 23:119-120. PMID: 26924532.
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PubMed
Youngstedt SD, Goff EE, Reynolds AM,
Kripke D
, Irwin MR, Bootzin RR, Khan N, Jean-Louis G. Has adult sleep duration declined over the last 50+ years? Sleep Med Rev. 2016 Aug; 28:69-85. PMID: 26478985; PMCID: PMC4769964 [Available on 08/01/17].
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Kripke D
. Is suvorexant a better choice than alternative hypnotics? F1000Res. 2015; 4:456. PMID: 26594338; PMCID: PMC4648222.
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Dawson A, Loving RT, Gordon RM, Abel SL, Loewy D,
Kripke D
, Kline LE. Type III home sleep testing versus pulse oximetry: is the respiratory disturbance index better than the oxygen desaturation index to predict the apnoea-hypopnoea index measured during laboratory polysomnography? BMJ Open. 2015 Jun 30; 5(6):e007956. PMID: 26129636; PMCID: PMC4486950.
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PubMed Central
Kripke D
. Do hypnotic drugs cause cancer, like cigarettes? Sleep Med. 2015 Dec; 16(12):1550-1. PMID: 26210392.
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PubMed
Kripke D
, Elliott JA, Welsh DK, Youngstedt SD. Photoperiodic and circadian bifurcation theories of depression and mania. F1000Res. 2015; 4:107. PMID: 26180634; PMCID: PMC4490783.
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PubMed Central
Kripke D
. A breakthrough treatment for major depression. J Clin Psychiatry. 2015 May; 76(5):e660-1. PMID: 26035202.
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PubMed
Kripke D
, Kline LE, Nievergelt CM, Murray SS, Shadan FF, Dawson A, Poceta JS, Cronin J, Jamil SM, Tranah GJ, Loving RT, Grizas AP, Hahn EK. Genetic variants associated with sleep disorders. Sleep Med. 2015 Feb; 16(2):217-24. PMID: 25660813; PMCID: PMC4352103.
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Kripke D
, Klimecki WT, Nievergelt CM, Rex KM, Murray SS, Shekhtman T, Tranah GJ, Loving RT, Lee HJ, Rhee MK, Shadan FF, Poceta JS, Jamil SM, Kline LE, Kelsoe JR. Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles. Psychiatry Investig. 2014 Oct; 11(4):345-62. PMID: 25395965; PMCID: PMC4225198.
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Kripke D
. "Rebound" is not an appropriate criterion for withdrawal insomnia. Sleep Med. 2014 Dec; 15(12):1594. PMID: 25441753.
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PubMed
Kripke D
. Hypnotics cause insomnia: evidence from clinical trials. Sleep Med. 2014 Sep; 15(9):1168-9. PMID: 25152199.
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PubMed
Kripke D
, Langer RD. Evidence for harm, comment on ‘Use of benzodiazepines or benzodiazepine related drugs and the risk of cancer: a population-based case-control study’. Br J Clin Pharmacol. 2014 Jul; 78(1):186-7. PMID: 25083532; PMCID: PMC4168393.
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Meliska CJ, Martínez LF, López AM, Sorenson DL, Nowakowski S,
Kripke D
, Elliott J, Parry BL. Antepartum depression severity is increased during seasonally longer nights: relationship to melatonin and cortisol timing and quantity. Chronobiol Int. 2013 Nov; 30(9):1160-73. PMID: 23998286; PMCID: PMC4041493.
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Youngstedt SD, Jean-Louis G, Bootzin RR,
Kripke D
, Cooper J, Dean LR, Catao F, James S, Vining C, Williams NJ, Irwin MR. Chronic moderate sleep restriction in older long sleepers and older average duration sleepers: a randomized controlled trial. Contemp Clin Trials. 2013 Sep; 36(1):175-86. PMID: 23811325; PMCID: PMC3860282.
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Kripke D
, Nievergelt CM, Tranah GJ, Murray SS, Rex KM, Grizas AP, Hahn EK, Lee HJ, Kelsoe JR, Kline LE. FMR1, circadian genes and depression: suggestive associations or false discovery? J Circadian Rhythms. 2013 Mar 23; 11(1):3. PMID: 23521777; PMCID: PMC3627611.
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Rhee MK, Lee HJ, Rex KM,
Kripke D
. Evaluation of two circadian rhythm questionnaires for screening for the delayed sleep phase disorder. Psychiatry Investig. 2012 Sep; 9(3):236-44. PMID: 22993522; PMCID: PMC3440472.
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Lee HJ, Woo HG, Greenwood TA,
Kripke D
, Kelsoe JR. A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder. J Affect Disord. 2013 Feb 20; 145(2):200-7. PMID: 22925353.
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PubMed
Kripke D
, Langer RD, Kline LE. Do no harm: not even to some degree. J Clin Sleep Med. 2012 Aug 15; 8(4):353-4. PMID: 22893763; PMCID: PMC3407251.
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Kripke D
, Langer RD, Kline LE. Hypnotics' association with mortality or cancer: a matched cohort study. BMJ Open. 2012; 2(1):e000850. PMID: 22371848; PMCID: PMC3293137.
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Kripke D
, Nievergelt CM, Tranah GJ, Murray SS, McCarthy MJ, Rex KM, Parimi N, Kelsoe JR. Polymorphisms in melatonin synthesis pathways: possible influences on depression. J Circadian Rhythms. 2011 Aug 09; 9:8. PMID: 21827647; PMCID: PMC3177871.
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PubMed Central
Kripke D
. Bright light treatment reduces symptoms in older adults with non-seasonal major depression. Evid Based Ment Health. 2011 Aug; 14(3):75. PMID: 21764874.
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PubMed
Lee HJ, Rex KM, Nievergelt CM, Kelsoe JR,
Kripke D
. Delayed sleep phase syndrome is related to seasonal affective disorder. J Affect Disord. 2011 Oct; 133(3):573-9. PMID: 21601293; PMCID: PMC3163003.
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Kripke D
. Is insomnia associated with mortality? Sleep. 2011 May 01; 34(5):555; author reply 557-8. PMID: 21532944; PMCID: PMC3079930.
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Kripke D
, Hahn EK, Grizas AP, Wadiak KH, Loving RT, Poceta JS, Shadan FF, Cronin JW, Kline LE. Wrist actigraphic scoring for sleep laboratory patients: algorithm development. J Sleep Res. 2010 Dec; 19(4):612-9. PMID: 20408923.
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PubMed
Kripke D
. Illumination and mood. Psychopharmacology (Berl). 2011 Feb; 213(4):833. PMID: 20953587; PMCID: PMC3033512.
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Kripke D
, Langer RD, Elliott JA, Klauber MR, Rex KM. Mortality related to actigraphic long and short sleep. Sleep Med. 2011 Jan; 12(1):28-33. PMID: 20870457; PMCID: PMC3010336.
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Kripke D
, Elliott JA, Youngstedt SD, Parry BL, Hauger RL, Rex KM. Weak evidence of bright light effects on human LH and FSH. J Circadian Rhythms. 2010 May 11; 8:5. PMID: 20459826; PMCID: PMC2885316.
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Youngstedt SD,
Kripke D
, Kline CE, Zielinski MR, Bogan RK. Lack of impairment in glucose tolerance: support for further investigation of sleep restriction in older long sleepers. J Sleep Res. 2010 Mar; 19(1 Pt 1):116-7. PMID: 20470263.
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PubMed
Kripke D
, Shadan FF, Dawson A, Cronin JW, Jamil SM, Grizas AP, Koziol JA, Kline LE. Genotyping sleep disorders patients. Psychiatry Investig. 2010 Mar; 7(1):36-42. PMID: 20396431; PMCID: PMC2848776.
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Kline CE, Zielinski MR, Devlin TM,
Kripke D
, Bogan RK, Youngstedt SD. Self-reported long sleep in older adults is closely related to objective time in bed. Sleep Biol Rhythms. 2010 Jan; 8(1):42-51. PMID: 25210491.
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PubMed
Grandner MA,
Kripke D
, Naidoo N, Langer RD. Relationships among dietary nutrients and subjective sleep, objective sleep, and napping in women. Sleep Med. 2010 Feb; 11(2):180-4. PMID: 20005774; PMCID: PMC2819566.
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Youngstedt SD, Kline CE, Zielinski MR,
Kripke D
, Devlin TM, Bogan RK, Wilcox S, Hardin JW. Tolerance of chronic 90-minute time-in-bed restriction in older long sleepers. Sleep. 2009 Nov; 32(11):1467-79. PMID: 19928386; PMCID: PMC2768953.
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Joya FL,
Kripke D
, Loving RT, Dawson A, Kline LE. Meta-analyses of hypnotics and infections: eszopiclone, ramelteon, zaleplon, and zolpidem. J Clin Sleep Med. 2009 Aug 15; 5(4):377-83. PMID: 19968019; PMCID: PMC2725260.
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Björkstén KS,
Kripke D
, Bjerregaard P. Accentuation of suicides but not homicides with rising latitudes of Greenland in the sunny months. BMC Psychiatry. 2009 May 08; 9:20. PMID: 19422728; PMCID: PMC2685778.
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Kripke D
. Do hypnotics cause death and cancer? The burden of proof. Sleep Med. 2009 Mar; 10(3):275-6. PMID: 19269891.
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PubMed
Kripke D
, Nievergelt CM, Joo E, Shekhtman T, Kelsoe JR. Circadian polymorphisms associated with affective disorders. J Circadian Rhythms. 2009 Jan 23; 7:2. PMID: 19166596; PMCID: PMC2661876.
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Chae KY,
Kripke D
, Poceta JS, Shadan F, Jamil SM, Cronin JW, Kline LE. Evaluation of immobility time for sleep latency in actigraphy. Sleep Med. 2009 Jun; 10(6):621-5. PMID: 19103508.
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PubMed
Dawson A, Abel SL, Loving RT, Dailey G, Shadan FF, Cronin JW,
Kripke D
, Kline LE. CPAP therapy of obstructive sleep apnea in type 2 diabetics improves glycemic control during sleep. J Clin Sleep Med. 2008 Dec 15; 4(6):538-42. PMID: 19110882; PMCID: PMC2603530.
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Parry BL, Meliska CJ, Sorenson DL, Lopez AM, Martinez LF, Nowakowski S, Elliott JA, Hauger RL,
Kripke D
. Plasma melatonin circadian rhythm disturbances during pregnancy and postpartum in depressed women and women with personal or family histories of depression. Am J Psychiatry. 2008 Dec; 165(12):1551-8. PMID: 18829869; PMCID: PMC3038788.
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Kripke D
. Possibility that certain hypnotics might cause cancer in skin. J Sleep Res. 2008 Sep; 17(3):245-50. PMID: 18844818.
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PubMed
Zielinski MR, Kline CE,
Kripke D
, Bogan RK, Youngstedt SD. No effect of 8-week time in bed restriction on glucose tolerance in older long sleepers. J Sleep Res. 2008 Dec; 17(4):412-9. PMID: 18691360; PMCID: PMC3244074.
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Kripke D
, Rex KM, Ancoli-Israel S, Nievergelt CM, Klimecki W, Kelsoe JR. Delayed sleep phase cases and controls. J Circadian Rhythms. 2008 Apr 29; 6:6. PMID: 18445295; PMCID: PMC2391143.
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Poceta JS, Parsons L, Engelland S,
Kripke D
. Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease. Sleep Med. 2009 Jan; 10(1):129-33. PMID: 18207455.
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PubMed
Kripke D
. Who should sponsor sleep disorders pharmaceutical trials? J Clin Sleep Med. 2007 Dec 15; 3(7):671-3. PMID: 18198797; PMCID: PMC2556906.
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PubMed Central
Park DH,
Kripke D
, Louis GJ, Elliott JA, Klauber MR, Rex KM, Tuunainen A, Langer RD. Self-reported sleep latency in postmenopausal women. J Korean Med Sci. 2007 Dec; 22(6):1007-14. PMID: 18162715; PMCID: PMC2694625.
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PubMed Central
Youngstedt SD,
Kripke D
. Does bright light have an anxiolytic effect? - an open trial. BMC Psychiatry. 2007 Oct 30; 7:62. PMID: 17971237; PMCID: PMC2194679.
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Kripke D
. Greater incidence of depression with hypnotic use than with placebo. BMC Psychiatry. 2007 Aug 21; 7:42. PMID: 17711589; PMCID: PMC1994947.
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Kripke D
, Elliott JA, Youngstedt SD, Rex KM. Circadian phase response curves to light in older and young women and men. J Circadian Rhythms. 2007 Jul 10; 5:4. PMID: 17623102; PMCID: PMC1988787.
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Park DH,
Kripke D
, Cole RJ. More prominent reactivity in mood than activity and sleep induced by differential light exposure due to seasonal and local differences. Chronobiol Int. 2007; 24(5):905-20. PMID: 17994345.
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PubMed
Lee AC, Mosaed S, Weinreb RN,
Kripke D
, Liu JH. Effect of laser trabeculoplasty on nocturnal intraocular pressure in medically treated glaucoma patients. Ophthalmology. 2007 Apr; 114(4):666-70. PMID: 17188360.
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PubMed
Grandner MA,
Kripke D
, Yoon IY, Youngstedt SD. Criterion validity of the Pittsburgh Sleep Quality Index: Investigation in a non-clinical sample. Sleep Biol Rhythms. 2006 Jun; 4(2):129-139. PMID: 22822303.
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Sit AJ, Weinreb RN, Crowston JG,
Kripke D
, Liu JH. Sustained effect of travoprost on diurnal and nocturnal intraocular pressure. Am J Ophthalmol. 2006 Jun; 141(6):1131-3. PMID: 16765686.
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PubMed
Grandner MA,
Kripke D
, Langer RD. Light exposure is related to social and emotional functioning and to quality of life in older women. Psychiatry Res. 2006 Jun 30; 143(1):35-42. PMID: 16725207; PMCID: PMC3685148.
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Kripke D
, Kline LE, Shadan FF, Dawson A, Poceta JS, Elliott JA. Melatonin effects on luteinizing hormone in postmenopausal women: a pilot clinical trial NCT00288262. BMC Womens Health. 2006 May 16; 6:8. PMID: 16704731; PMCID: PMC1481506.
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Nievergelt CM,
Kripke D
, Barrett TB, Burg E, Remick RA, Sadovnick AD, McElroy SL, Keck PE, Schork NJ, Kelsoe JR. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2006 Apr 05; 141B(3):234-41. PMID: 16528748; PMCID: PMC2651679.
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Kripke D
, Tuunainen A, Endo T. Benefits of light treatment for depression. Am J Psychiatry. 2006 Jan; 163(1):162-3; author reply 163. PMID: 16390913.
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PubMed
Jean-Louis G,
Kripke D
, Elliott JA, Zizi F, Wolintz AH, Lazzaro DR. Daily illumination exposure and melatonin: influence of ophthalmic dysfunction and sleep duration. J Circadian Rhythms. 2005 Dec 01; 3:13. PMID: 16321164; PMCID: PMC1325258.
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Loving RT,
Kripke D
, Elliott JA, Knickerbocker NC, Grandner MA. Bright light treatment of depression for older adults [ISRCTN55452501]. BMC Psychiatry. 2005 Nov 09; 5:41. PMID: 16283925; PMCID: PMC1298312.
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Loving RT,
Kripke D
, Knickerbocker NC, Grandner MA. Bright green light treatment of depression for older adults [ISRCTN69400161]. BMC Psychiatry. 2005 Nov 09; 5:42. PMID: 16283926; PMCID: PMC1309618.
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Youngstedt SD,
Kripke D
, Elliott JA, Rex KM. Circadian phase-shifting effects of a laboratory environment: a clinical trial with bright and dim light. J Circadian Rhythms. 2005 Sep 09; 3:11. PMID: 16153301; PMCID: PMC1224862.
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Kripke D
. Selective publication. Sleep. 2005 Mar; 28(3):370; author reply 371-2. PMID: 16173660.
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Nievergelt CM,
Kripke D
, Remick RA, Sadovnick AD, McElroy SL, Keck PE, Kelsoe JR. Examination of the clock gene Cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association. Psychiatr Genet. 2005 Mar; 15(1):45-52. PMID: 15722957.
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PubMed
Björkstén KS, Bjerregaard P,
Kripke D
. Suicides in the midnight sun--a study of seasonality in suicides in West Greenland. Psychiatry Res. 2005 Feb 28; 133(2-3):205-13. PMID: 15740996.
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PubMed
Kripke D
, Youngstedt SD, Elliott JA, Tuunainen A, Rex KM, Hauger RL, Marler MR. Circadian phase in adults of contrasting ages. Chronobiol Int. 2005; 22(4):695-709. PMID: 16147900.
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PubMed
Youngstedt SD, Leung A,
Kripke D
, Langer RD. Association of morning illumination and window covering with mood and sleep among post-menopausal women. Sleep Biol Rhythms. 2004 Oct; 2(3):174-183. PMID: 25374475.
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PubMed
Liu JH,
Kripke D
, Weinreb RN. Comparison of the nocturnal effects of once-daily timolol and latanoprost on intraocular pressure. Am J Ophthalmol. 2004 Sep; 138(3):389-95. PMID: 15364220.
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PubMed
Yoon IY,
Kripke D
, Elliott JA, Langer RD. Naps and circadian rhythms in postmenopausal women. J Gerontol A Biol Sci Med Sci. 2004 Aug; 59(8):844-8. PMID: 15345736.
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PubMed
Youngstedt SD,
Kripke D
. Long sleep and mortality: rationale for sleep restriction. Sleep Med Rev. 2004 Jun; 8(3):159-74. PMID: 15144959.
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PubMed
Kripke D
, Jean-Louis G, Elliott JA, Klauber MR, Rex KM, Tuunainen A, Langer RD. Ethnicity, sleep, mood, and illumination in postmenopausal women. BMC Psychiatry. 2004 Apr 07; 4:8. PMID: 15070419; PMCID: PMC400740.
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Grandner MA,
Kripke D
. Self-reported sleep complaints with long and short sleep: a nationally representative sample. Psychosom Med. 2004 Mar-Apr; 66(2):239-41. PMID: 15039509; PMCID: PMC3687531.
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Kripke D
. Do we sleep too much? Sleep. 2004 Feb 01; 27(1):13-4. PMID: 14998231.
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Wirz-Justice A, Terman M, Oren DA, Goodwin FK,
Kripke D
, Whybrow PC, Wisner KL, Wu JC, Lam RW, Berger M, Danilenko KV, Kasper S, Smeraldi E, Takahashi K, Thompson C, van den Hoofdakker RH. Brightening depression. Science. 2004 Jan 23; 303(5657):467-9. PMID: 14739440.
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PubMed
Parry BL, Meliska CJ, Martinez LF, Basavaraj N, Zirpoli GG, Sorenson D, Maurer EL, Lopez A, Markova K, Gamst A, Wolfson T, Hauger R,
Kripke D
. Menopause: neuroendocrine changes and hormone replacement therapy. J Am Med Womens Assoc (1972). 2004; 59(2):135-45. PMID: 15134429.
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Kripke D
, Clopton P, Marler MR, Youngstedt SD, Elliott JA. PRC bisection tests. Chronobiol Int. 2003 Nov; 20(6):1117-23. PMID: 14680147.
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PubMed
Liu JH, Bouligny RP,
Kripke D
, Weinreb RN. Nocturnal elevation of intraocular pressure is detectable in the sitting position. Invest Ophthalmol Vis Sci. 2003 Oct; 44(10):4439-42. PMID: 14507890.
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PubMed
Yoon IY,
Kripke D
, Elliott JA, Youngstedt SD, Rex KM, Hauger RL. Age-related changes of circadian rhythms and sleep-wake cycles. J Am Geriatr Soc. 2003 Aug; 51(8):1085-91. PMID: 12890070.
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PubMed
Liu JH, Gokhale PA, Loving RT,
Kripke D
, Weinreb RN. Laboratory assessment of diurnal and nocturnal ocular perfusion pressures in humans. J Ocul Pharmacol Ther. 2003 Aug; 19(4):291-7. PMID: 12964954.
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Levine DW, Kaplan RM,
Kripke D
, Bowen DJ, Naughton MJ, Shumaker SA. Factor structure and measurement invariance of the Women's Health Initiative Insomnia Rating Scale. Psychol Assess. 2003 Jun; 15(2):123-36. PMID: 12847773.
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Levine DW,
Kripke D
, Kaplan RM, Lewis MA, Naughton MJ, Bowen DJ, Shumaker SA. Reliability and validity of the Women's Health Initiative Insomnia Rating Scale. Psychol Assess. 2003 Jun; 15(2):137-48. PMID: 12847774.
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Yoon IY,
Kripke D
, Youngstedt SD, Elliott JA. Actigraphy suggests age-related differences in napping and nocturnal sleep. J Sleep Res. 2003 Jun; 12(2):87-93. PMID: 12753345.
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Wang EJ,
Kripke D
, Stein MT, Parry BL. Measurement of illumination exposure in postpartum women. BMC Psychiatry. 2003 May 13; 3:5. PMID: 12744724; PMCID: PMC156656.
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,
PubMed Central
Kripke D
, Youngstedt SD, Rex KM, Klauber MR, Elliott JA. Melatonin excretion with affect disorders over age 60. Psychiatry Res. 2003 May 01; 118(1):47-54. PMID: 12759161.
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Yoon IY,
Kripke D
, Elliott JA, Youngstedt SD. Luteinizing hormone following light exposure in healthy young men. Neurosci Lett. 2003 Apr 24; 341(1):25-8. PMID: 12676335.
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Kripke D
. Ineffectiveness of intermittent zolpidem. Sleep Med Rev. 2003 Apr; 7(2):193; author reply 195-6. PMID: 12628218.
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Liu JH, Zhang X,
Kripke D
, Weinreb RN. Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes. Invest Ophthalmol Vis Sci. 2003 Apr; 44(4):1586-90. PMID: 12657596.
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Youngstedt SD, Perlis ML, O'Brien PM, Palmer CR, Smith MT, Orff HJ,
Kripke D
. No association of sleep with total daily physical activity in normal sleepers. Physiol Behav. 2003 Mar; 78(3):395-401. PMID: 12676274.
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Palmer CR,
Kripke D
, Savage HC, Cindrich LA, Loving RT, Elliott JA. Efficacy of enhanced evening light for advanced sleep phase syndrome. Behav Sleep Med. 2003; 1(4):213-26. PMID: 15602801.
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Smith JS,
Kripke D
, Elliott JA, Youngstedt SD. Illumination of upper and middle visual fields produces equivalent suppression of melatonin in older volunteers. Chronobiol Int. 2002 Sep; 19(5):883-91. PMID: 12405551.
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PubMed
Liu JH,
Kripke D
, Twa MD, Gokhale PA, Jones EI, Park EH, Meehan JE, Weinreb RN. Twenty-four-hour pattern of intraocular pressure in young adults with moderate to severe myopia. Invest Ophthalmol Vis Sci. 2002 Jul; 43(7):2351-5. PMID: 12091437.
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Youngstedt SD,
Kripke D
, Elliott JA, Assmus JD. No association of 6-sulfatoxymelatonin with in-bed 60-Hz magnetic field exposure or illumination level among older adults. Environ Res. 2002 Jul; 89(3):201-9. PMID: 12176004.
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Tuunainen A,
Kripke D
, Elliott JA, Assmus JD, Rex KM, Klauber MR, Langer RD. Depression and endogenous melatonin in postmenopausal women. J Affect Disord. 2002 May; 69(1-3):149-58. PMID: 12103461.
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Gehrman P, Stepnowsky C, Cohen-Zion M, Marler M,
Kripke D
, Ancoli-Israel S. Long-term follow-up of periodic limb movements in sleep in older adults. Sleep. 2002 May 01; 25(3):340-3. PMID: 12003165.
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Wallace-Guy GM,
Kripke D
, Jean-Louis G, Langer RD, Elliott JA, Tuunainen A. Evening light exposure: implications for sleep and depression. J Am Geriatr Soc. 2002 Apr; 50(4):738-9. PMID: 11982677.
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Kripke D
, Garfinkel L, Wingard DL, Klauber MR, Marler MR. Mortality associated with sleep duration and insomnia. Arch Gen Psychiatry. 2002 Feb; 59(2):131-6. PMID: 11825133.
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PubMed
Cole RJ, Smith JS, Alcalá YC, Elliott JA,
Kripke D
. Bright-light mask treatment of delayed sleep phase syndrome. J Biol Rhythms. 2002 Feb; 17(1):89-101. PMID: 11837952.
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PubMed
Ancoli-Israel S, Martin JL,
Kripke D
, Marler M, Klauber MR. Effect of light treatment on sleep and circadian rhythms in demented nursing home patients. J Am Geriatr Soc. 2002 Feb; 50(2):282-9. PMID: 12028210; PMCID: PMC2764401.
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PubMed
,
PubMed Central
Loving RT,
Kripke D
, Shuchter SR. Bright light augments antidepressant effects of medication and wake therapy. Depress Anxiety. 2002; 16(1):1-3. PMID: 12203667.
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PubMed
Youngstedt SD,
Kripke D
, Elliott JA. Circadian phase-delaying effects of bright light alone and combined with exercise in humans. Am J Physiol Regul Integr Comp Physiol. 2002 Jan; 282(1):R259-66. PMID: 11742846.
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PubMed
Ando K,
Kripke D
, Ancoli-Israel S. Delayed and advanced sleep phase symptoms. Isr J Psychiatry Relat Sci. 2002; 39(1):11-8. PMID: 12013705.
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PubMed
Kripke D
, Brunner R, Freeman R, Hendrix SL, Jackson RD, Masaki K, Carter RA. Sleep Complaints of Postmenopausal Women. Clin J Womens Health. 2001 Dec 01; 1(5):244-252. PMID: 21461131.
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PubMed
Kripke D
. Chronic hypnotic use: deadly risks, doubtful benefit. REVIEW ARTICLE. Sleep Med Rev. 2000 Feb; 4(1):5-20. PMID: 12531158.
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PubMed
Kripke D
. Light treatment for nonseasonal depression: speed, efficacy, and combined treatment. J Affect Disord. 1998 May; 49(2):109-17. PMID: 9609674.
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PubMed
Kripke D
, Elliot JA, Youngstedt SD, Smith JS. Melatonin: marvel or marker? Ann Med. 1998 Feb; 30(1):81-7. PMID: 9556093.
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1998
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2001
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2002
12
2003
14
2004
9
2005
8
2006
7
2007
6
2008
7
2009
6
2010
7
2011
4
2012
4
2013
3
2014
5
2015
7
2016
4
2017
1
Daniel's Networks
Concepts
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Circadian Rhythm
Hypnotics and Sedatives
Sleep
Sleep Initiation and Maintenance Disorders
Phototherapy
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Kelsoe, John
Parry, Barbara
Nievergelt, Caroline
Murray, Sarah
Kline, Lawrence
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