Colleen Mchugh

Title(s)	Assistant Professor, Chemistry and Biochemistry
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Mechanisms of large non-coding RNA regulation of gene expression
NIH R00GM120494Sep 1, 2016 - Dec 31, 2020
Role: Principal Investigator

Mechanisms of large non-coding RNA regulation of gene expression
NIH K99GM120494Sep 1, 2016 - Aug 31, 2018
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Dissection of protein and RNA regions required for SPEN binding to XIST A-repeat RNA. RNA. 2024 Feb 16; 30(3):240-255. Button AC, Hall SD, Ashley EL, McHugh CA. PMID: 38164599; PMCID: PMC10870365.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Translation:Humans Cells
Streamlined Purification of RNA-Protein Complexes Using UV Cross-Linking and RNA Antisense Purification. Methods Mol Biol. 2023; 2666:213-229. Trang N, Su T, Hall S, Boutros N, Kong B, Huang C, McHugh CA. PMID: 37166668.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Translation:Cells
Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors. Front Genome Ed. 2022; 4:923718. Burnett CA, Wong AT, Vasquez CA, McHugh CA, Yeo GW, Komor AC. PMID: 35910415; PMCID: PMC9333457.

View in: PubMed Mentions: 2
RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells. Methods Mol Biol. 2018; 1649:473-488. McHugh CA, Guttman M. PMID: 29130217.

View in: PubMed Mentions: 38 Fields:
Mol Molecular Biology
Translation:Animals Cells
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature. 2015 May 14; 521(7551):232-6. McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M. PMID: 25915022; PMCID: PMC4516396.

View in: PubMed Mentions: 553 Fields:
Sci Science
Translation:Animals Cells
A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress. EMBO J. 2014 Sep 01; 33(17):1896-911. McHugh CA, Fontana J, Nemecek D, Cheng N, Aksyuk AA, Heymann JB, Winkler DC, Lam AS, Wall JS, Steven AC, Hoiczyk E. PMID: 25024436; PMCID: PMC4195785.

View in: PubMed Mentions: 70 Fields:
Bio Biotechnology Mol Molecular Biology
Translation:Cells
Methods for comprehensive experimental identification of RNA-protein interactions. Genome Biol. 2014 Jan 27; 15(1):203. McHugh CA, Russell P, Guttman M. PMID: 24467948; PMCID: PMC4054858.

View in: PubMed Mentions: 88 Fields:
Gen Genetics
Translation:Humans Animals Cells
BacM, an N-terminally processed bactofilin of Myxococcus xanthus, is crucial for proper cell shape. Mol Microbiol. 2011 May; 80(4):1031-51. Koch MK, McHugh CA, Hoiczyk E. PMID: 21414039; PMCID: PMC3091990.

View in: PubMed Mentions: 37 Fields:
Mic Microbiology Mol Molecular Biology
Translation:Cells
Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus. Mol Microbiol. 2009 Oct; 74(2):497-517. Hoiczyk E, Ring MW, McHugh CA, Schwär G, Bode E, Krug D, Altmeyer MO, Lu JZ, Bode HB. PMID: 19788540; PMCID: PMC2877170.

View in: PubMed Mentions: 23 Fields:
Mic Microbiology Mol Molecular Biology
Translation:Cells
The Anopheles gambiae adult midgut peritrophic matrix proteome. Insect Biochem Mol Biol. 2009 Feb; 39(2):125-34. Dinglasan RR, Devenport M, Florens L, Johnson JR, McHugh CA, Donnelly-Doman M, Carucci DJ, Yates JR, Jacobs-Lorena M. PMID: 19038338; PMCID: PMC2684889.

View in: PubMed Mentions: 51 Fields:
Bio Biochemistry Mol Molecular Biology Zoo Zoology
Translation:Humans Animals Cells PHPublic Health
Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site. BMC Struct Biol. 2007 Nov 06; 7:72. Carra JH, McHugh CA, Mulligan S, Machiesky LM, Soares AS, Millard CB. PMID: 17986339; PMCID: PMC2194779.

View in: PubMed Mentions: 11 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Cells
Improved stability of a protein vaccine through elimination of a partially unfolded state. Protein Sci. 2004 Oct; 13(10):2736-43. McHugh CA, Tammariello RF, Millard CB, Carra JH. PMID: 15340172; PMCID: PMC2286567.

View in: PubMed Mentions: 24 Fields:
Bio Biochemistry
Translation:Humans Animals Cells