Bradley Moore

Title(s)Professor, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Biosynthesis and Monitoring of the Cyanobacterial Toxin Anatoxin-a(s)
    NIH R21ES032056Aug 13, 2020 - Jul 31, 2022
    Role: Principal Investigator
    Natural Sources and Microbial Transformation of Marine Halogenated Pollutants
    NIH R01ES030316Sep 15, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Targeted discovery of antibiotics from cave bacteria
    NIH R01AI117712Mar 1, 2016 - Feb 28, 2021
    Role: Principal Investigator
    Scripps Center for Ocean and Human Health
    NIH P01ES021921Sep 24, 2012 - Jul 31, 2018
    Role: Principal Investigator
    Experiment based genome mining of ribosomal natural products
    NIH R01GM097509Apr 1, 2012 - Feb 28, 2017
    Role: Principal Investigator
    Natural Product Genome Mining
    NIH R01GM085770Aug 1, 2009 - Jul 31, 2025
    Role: Principal Investigator
    Salinosporamide Biosynthesis and Engineering
    NIH R01CA127622Apr 1, 2007 - May 31, 2018
    Role: Principal Investigator
    Type III Polyketide Synthases: Structure and Mechanism
    NIH R01AI052443Jun 15, 2002 - May 31, 2008
    Role: Principal Investigator
    Biosynthesis of Marine Polyketide Antibiotics
    NIH R01AI047818Aug 1, 2000 - Dec 31, 2022
    Role: Principal Investigator
    Biosynthesis of Marine Polyketide Antibiotics
    NIH R56AI047818Aug 1, 2000 - Dec 18, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Discovery of Latent Cannabichromene Cyclase Activity in Marine Bacterial Flavoenzymes. ACS Synth Biol. 2024 Mar 08. Love AC, Purdy TN, Hubert FM, Kirwan EJ, Holland DC, Moore BS. PMID: 38459634.
      View in: PubMed   Mentions:    Fields:    
    2. Giant polyketide synthase enzymes biosynthesize a giant marine polyether biotoxin. bioRxiv. 2024 Jan 31. Fallon TR, Shende VV, Wierzbicki IH, Auber RP, Gonzalez DJ, Wisecaver JH, Moore BS. PMID: 38352448; PMCID: PMC10862718.
      View in: PubMed   Mentions:
    3. The shikimate pathway: gateway to metabolic diversity. Nat Prod Rep. 2024 Jan 03. Shende VV, Bauman KD, Moore BS. PMID: 38170905.
      View in: PubMed   Mentions: 1     Fields:    
    4. Biosynthesis of Haloterpenoids in Red Algae via Microbial-like Type I Terpene Synthases. ACS Chem Biol. 2024 Jan 19; 19(1):185-192. Steele TS, Burkhardt I, Moore ML, de Rond T, Bone HK, Barry K, Bunting VM, Grimwood J, Handley LH, Rajasekar S, Talag J, Michael TP, Moore BS. PMID: 38081799.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Unveiling a CAAX Protease-Like Protein Involved in Didemnin Drug Maturation and Secretion. Adv Sci (Weinh). 2024 Jan; 11(4):e2306044. Zou X, Hui Z, Shepherd RA, Zhao S, Wu Y, Shen Z, Pang C, Zhou S, Yu Z, Zhou J, Moore BS, Sanchez LM, Tang X. PMID: 38032137; PMCID: PMC10811503.
      View in: PubMed   Mentions:    Fields:    
    6. Molecular Forecasting of Domoic Acid during a Pervasive Toxic Diatom Bloom. bioRxiv. 2023 Nov 05. Brunson JK, Thukral M, Ryan JP, Anderson CR, Kolody BC, James C, Chavez FP, Leaw CP, Rabines AJ, Venepally P, Zheng H, Kudela RM, Smith GJ, Moore BS, Allen AE. PMID: 37961417; PMCID: PMC10635071.
      View in: PubMed   Mentions:
    7. Linking bacterial tetrabromopyrrole biosynthesis to coral metamorphosis. ISME Commun. 2023 Sep 19; 3(1):98. Alker AT, Farrell MV, Demko AM, Purdy TN, Adak S, Moore BS, Sneed JM, Paul VJ, Shikuma NJ. PMID: 37726481; PMCID: PMC10509201.
      View in: PubMed   Mentions: 1  
    8. Enzymatic Halogenation of Terminal Alkynes. J Am Chem Soc. 2023 08 30; 145(34):18716-18721. Lukowski AL, Hubert FM, Ngo TE, Avalon NE, Gerwick WH, Moore BS. PMID: 37594919; PMCID: PMC10486310.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    9. Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme. bioRxiv. 2023 Aug 03. Adak S, Ye N, Calderone LA, Schäfer RJB, Lukowski AL, Pandelia ME, Drennan CL, Moore BS. PMID: 37577561; PMCID: PMC10418191.
      View in: PubMed   Mentions:
    10. A modular plasmid toolkit applied in marine bacteria reveals functional insights during bacteria-stimulated metamorphosis. mBio. 2023 08 31; 14(4):e0150223. Alker AT, Farrell MV, Aspiras AE, Dunbar TL, Fedoriouk A, Jones JE, Mikhail SR, Salcedo GY, Moore BS, Shikuma NJ. PMID: 37530556; PMCID: PMC10470607.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    11. Mechanistic and Structural Insights into a Divergent PLP-Dependent l-Enduracididine Cyclase from a Toxic Cyanobacterium. ACS Catal. 2023 Jul 21; 13(14):9817-9828. Cordoza JL, Chen PY, Blaustein LR, Lima ST, Fiore MF, Chekan JR, Moore BS, McKinnie SMK. PMID: 37497377; PMCID: PMC10367076.
      View in: PubMed   Mentions:
    12. Extreme genome diversity and cryptic speciation in a harmful algal-bloom-forming eukaryote. Curr Biol. 2023 06 05; 33(11):2246-2259.e8. Wisecaver JH, Auber RP, Pendleton AL, Watervoort NF, Fallon TR, Riedling OL, Manning SR, Moore BS, Driscoll WW. PMID: 37224809; PMCID: PMC10247466.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    13. Linking bacterial tetrabromopyrrole biosynthesis to coral metamorphosis. bioRxiv. 2023 May 09. Alker AT, Farrell MV, Demko AM, Purdy TN, Adak S, Moore BS, Sneed JM, Paul VJ, Shikuma NJ. PMID: 37214991; PMCID: PMC10197590.
      View in: PubMed   Mentions:
    14. Mechanistic and structural insights into a divergent PLP-dependent L-enduracididine cyclase from a toxic cyanobacterium. bioRxiv. 2023 Mar 21. Cordoza JL, Chen PY, Blaustein LR, Lima ST, Fiore MF, Chekan JR, Moore BS, McKinnie SMK. PMID: 36993528; PMCID: PMC10055224.
      View in: PubMed   Mentions:
    15. Terpene biosynthesis in marine sponge animals. Proc Natl Acad Sci U S A. 2023 02 28; 120(9):e2220934120. Wilson K, de Rond T, Burkhardt I, Steele TS, Schäfer RJB, Podell S, Allen EE, Moore BS. PMID: 36802428; PMCID: PMC9992776.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    16. A modular plasmid toolkit applied in marine Proteobacteria reveals functional insights during bacteria-stimulated metamorphosis. bioRxiv. 2023 Jan 31. Alker AT, Aspiras AE, Dunbar TL, Farrell MV, Fedoriouk A, Jones JE, Mikhail SR, Salcedo GY, Moore BS, Shikuma NJ. PMID: 36778221; PMCID: PMC9915575.
      View in: PubMed   Mentions:
    17. Genomic and Spectroscopic Signature-Based Discovery of Natural Macrolactams. J Am Chem Soc. 2023 01 25; 145(3):1886-1896. Shin YH, Im JH, Kang I, Kim E, Jang SC, Cho E, Shin D, Hwang S, Du YE, Huynh TH, Ko K, Ko YJ, Nam SJ, Awakawa T, Lee J, Hong S, Abe I, Moore BS, Fenical W, Yoon YJ, Cho JC, Lee SK, Oh KB, Oh DC. PMID: 36634356.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    18. Identification of Isonitrile-Containing Natural Products in Complex Biological Matrices through Ligation with Chlorooximes. Chemistry. 2023 Jan 27; 29(6):e202203277. Schäfer RJB, Wilson K, Biedermann M, Moore BS, Sieber S, Wennemers H. PMID: 36331430; PMCID: PMC9892309.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    19. The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function. J Biol Chem. 2022 10; 298(10):102480. Klau LJ, Podell S, Creamer KE, Demko AM, Singh HW, Allen EE, Moore BS, Ziemert N, Letzel AC, Jensen PR. PMID: 36108739; PMCID: PMC9582728.
      View in: PubMed   Mentions: 15     Fields:    
    20. Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis. Biochemistry. 2022 09 06; 61(17):1844-1852. Chen PY, Adak S, Chekan JR, Liscombe DK, Miyanaga A, Bernhardt P, Diethelm S, Fielding EN, George JH, Miles ZD, Murray LAM, Steele TS, Winter JM, Noel JP, Moore BS. PMID: 35985031; PMCID: PMC10978243.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    21. Ancient plant-like terpene biosynthesis in corals. Nat Chem Biol. 2022 06; 18(6):664-669. Burkhardt I, de Rond T, Chen PY, Moore BS. PMID: 35606558; PMCID: PMC9179088.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    22. Biosynthesis of Guanitoxin Enables Global Environmental Detection in Freshwater Cyanobacteria. J Am Chem Soc. 2022 06 01; 144(21):9372-9379. Lima ST, Fallon TR, Cordoza JL, Chekan JR, Delbaje E, Hopiavuori AR, Alvarenga DO, Wood SM, Luhavaya H, Baumgartner JT, Dörr FA, Etchegaray A, Pinto E, McKinnie SMK, Fiore MF, Moore BS. PMID: 35583956; PMCID: PMC9247102.
      View in: PubMed   Mentions: 10     Fields:    Translation:CellsPHPublic Health
    23. Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead. Nat Chem Biol. 2022 05; 18(5):538-546. Bauman KD, Shende VV, Chen PY, Trivella DBB, Gulder TAM, Vellalath S, Romo D, Moore BS. PMID: 35314816; PMCID: PMC9058210.
      View in: PubMed   Mentions: 4     Fields:    
    24. From Tryptophan to Toxin: Nature's Convergent Biosynthetic Strategy to Aetokthonotoxin. J Am Chem Soc. 2022 02 23; 144(7):2861-2866. Adak S, Lukowski AL, Schäfer RJB, Moore BS. PMID: 35142504; PMCID: PMC9004672.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    25. Domoic acid biosynthesis in the red alga Chondria armata suggests a complex evolutionary history for toxin production. Proc Natl Acad Sci U S A. 2022 02 08; 119(6). Steele TS, Brunson JK, Maeno Y, Terada R, Allen AE, Yotsu-Yamashita M, Chekan JR, Moore BS. PMID: 35110408; PMCID: PMC8833176.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    26. Harnessing ortho-Quinone Methides in Natural Product Biosynthesis and Biocatalysis. J Nat Prod. 2022 03 25; 85(3):688-701. Purdy TN, Moore BS, Lukowski AL. PMID: 35108487; PMCID: PMC9006567.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    27. A Diazo-Hooker Reaction, Inspired by the Biosynthesis of Azamerone. Org Lett. 2022 01 21; 24(2):490-495. Yahiaoui O, Murray LAM, Zhao F, Moore BS, Houk KN, Liu F, George JH. PMID: 34994200; PMCID: PMC9006554.
      View in: PubMed   Mentions:    Fields:    
    28. Marine and Anthropogenic Bromopyrroles Alter Cellular Ca2+ Dynamics of Murine Cortical Neuronal Networks by Targeting the Ryanodine Receptor and Sarco/Endoplasmic Reticulum Ca2+-ATPase. Environ Sci Technol. 2021 12 07; 55(23):16023-16033. Zheng J, Antrobus S, Feng W, Purdy TN, Moore BS, Pessah IN. PMID: 34788016; PMCID: PMC8813095.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Genome mining methods to discover bioactive natural products. Nat Prod Rep. 2021 11 17; 38(11):2100-2129. Bauman KD, Butler KS, Moore BS, Chekan JR. PMID: 34734626; PMCID: PMC8597713.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    30. A biosynthetic pathway to aromatic amines that uses glycyl-tRNA as nitrogen donor. Nat Chem. 2022 01; 14(1):71-77. Daniels PN, Lee H, Splain RA, Ting CP, Zhu L, Zhao X, Moore BS, van der Donk WA. PMID: 34725492; PMCID: PMC8758506.
      View in: PubMed   Mentions: 13     Fields:    
    31. Cryptic halogenation reactions in natural product biosynthesis. Nat Prod Rep. 2021 10 20; 38(10):1760-1774. Adak S, Moore BS. PMID: 34676862; PMCID: PMC8542889.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    32. Co-occurrence of enzyme domains guides the discovery of an oxazolone synthetase. Nat Chem Biol. 2021 07; 17(7):794-799. de Rond T, Asay JE, Moore BS. PMID: 34099916; PMCID: PMC8238888.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    33. Mining genomes to illuminate the specialized chemistry of life. Nat Rev Genet. 2021 09; 22(9):553-571. Medema MH, de Rond T, Moore BS. PMID: 34083778; PMCID: PMC8364890.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    34. Phylogenetic analysis of the salinipostin γ-butyrolactone gene cluster uncovers new potential for bacterial signalling-molecule diversity. Microb Genom. 2021 05; 7(5). Creamer KE, Kudo Y, Moore BS, Jensen PR. PMID: 33979276; PMCID: PMC8209734.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    35. A community resource for paired genomic and metabolomic data mining. Nat Chem Biol. 2021 04; 17(4):363-368. Schorn MA, Verhoeven S, Ridder L, Huber F, Acharya DD, Aksenov AA, Aleti G, Moghaddam JA, Aron AT, Aziz S, Bauermeister A, Bauman KD, Baunach M, Beemelmanns C, Beman JM, Berlanga-Clavero MV, Blacutt AA, Bode HB, Boullie A, Brejnrod A, Bugni TS, Calteau A, Cao L, Carrión VJ, Castelo-Branco R, Chanana S, Chase AB, Chevrette MG, Costa-Lotufo LV, Crawford JM, Currie CR, Cuypers B, Dang T, de Rond T, Demko AM, Dittmann E, Du C, Drozd C, Dujardin JC, Dutton RJ, Edlund A, Fewer DP, Garg N, Gauglitz JM, Gentry EC, Gerwick L, Glukhov E, Gross H, Gugger M, Guillén Matus DG, Helfrich EJN, Hempel BF, Hur JS, Iorio M, Jensen PR, Kang KB, Kaysser L, Kelleher NL, Kim CS, Kim KH, Koester I, König GM, Leao T, Lee SR, Lee YY, Li X, Little JC, Maloney KN, Männle D, Martin H C, McAvoy AC, Metcalf WW, Mohimani H, Molina-Santiago C, Moore BS, Mullowney MW, Muskat M, Nothias LF, O'Neill EC, Parkinson EI, Petras D, Piel J, Pierce EC, Pires K, Reher R, Romero D, Roper MC, Rust M, Saad H, Saenz C, Sanchez LM, Sørensen SJ, Sosio M, Süssmuth RD, Sweeney D, Tahlan K, Thomson RJ, Tobias NJ, Trindade-Silva AE, van Wezel GP, Wang M, Weldon KC, Zhang F, Ziemert N, Duncan KR, Crüsemann M, Rogers S, Dorrestein PC, Medema MH, van der Hooft JJJ. PMID: 33589842; PMCID: PMC7987574.
      View in: PubMed   Mentions: 49     Fields:    
    36. Discovery and Biosynthesis of Tetrachlorizine Reveals Enzymatic Benzylic Dehydrogenation via an ortho-Quinone Methide. J Am Chem Soc. 2021 03 17; 143(10):3682-3686. Purdy TN, Kim MC, Cullum R, Fenical W, Moore BS. PMID: 33656337; PMCID: PMC8318071.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    37. Expansion of Gamma-Butyrolactone Signaling Molecule Biosynthesis to Phosphotriester Natural Products. ACS Chem Biol. 2020 12 18; 15(12):3253-3261. Kudo Y, Awakawa T, Du YL, Jordan PA, Creamer KE, Jensen PR, Linington RG, Ryan KS, Moore BS. PMID: 33232109; PMCID: PMC8217639.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    38. Enzymes in natural product total synthesis. Nat Prod Rep. 2020 10 01; 37(10):1292-1293. Moore BS, Gulder TAM. PMID: 33034327.
      View in: PubMed   Mentions: 2     Fields:    
    39. Genetic examination of the marine bacterium Pseudoalteromonas luteoviolacea and effects of its metamorphosis-inducing factors. Environ Microbiol. 2020 11; 22(11):4689-4701. Alker AT, Delherbe N, Purdy TN, Moore BS, Shikuma NJ. PMID: 32840026; PMCID: PMC8214333.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    40. Biosynthesis of marine toxins. Curr Opin Chem Biol. 2020 12; 59:119-129. Chekan JR, Fallon TR, Moore BS. PMID: 32731193.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    41. Site-Directed Mutagenesis of Large Biosynthetic Gene Clusters via Oligonucleotide Recombineering and CRISPR/Cas9 Targeting. ACS Synth Biol. 2020 07 17; 9(7):1917-1922. Zhang JJ, Moore BS. PMID: 32584552; PMCID: PMC8142379.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    42. Wearable Shoulder Exoskeleton with Spring-Cam Mechanism for Customizable, Nonlinear Gravity Compensation. Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:4926-4929. Asgari M, Hall PT, Moore BS, Crouch DL. PMID: 33019093.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Meroterpenoid natural products from Streptomyces bacteria - the evolution of chemoenzymatic syntheses. Nat Prod Rep. 2020 10 01; 37(10):1334-1366. Murray LAM, McKinnie SMK, Moore BS, George JH. PMID: 32602506; PMCID: PMC7578067.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    44. A genomic view of trophic and metabolic diversity in clade-specific Lamellodysidea sponge microbiomes. Microbiome. 2020 06 23; 8(1):97. Podell S, Blanton JM, Oliver A, Schorn MA, Agarwal V, Biggs JS, Moore BS, Allen EE. PMID: 32576248; PMCID: PMC7313196.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    45. Comparative Genomics and Metabolomics in the Genus Nocardia. mSystems. 2020 Jun 02; 5(3). Männle D, McKinnie SMK, Mantri SS, Steinke K, Lu Z, Moore BS, Ziemert N, Kaysser L. PMID: 32487740; PMCID: PMC7413640.
      View in: PubMed   Mentions: 22     Fields:    
    46. Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an N-prenyltransferase. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):12799-12805. Chekan JR, McKinnie SMK, Noel JP, Moore BS. PMID: 32457155; PMCID: PMC7293706.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    47. Nonlinear Biosynthetic Assembly of Alpiniamide by a Hybrid cis/trans-AT PKS-NRPS. ACS Chem Biol. 2020 04 17; 15(4):1067-1077. Sigrist R, Luhavaya H, McKinnie SMK, Ferreira da Silva A, Jurberg ID, Moore BS, Gonzaga de Oliveira L. PMID: 32195572; PMCID: PMC7286424.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    48. Guanitoxin, re-naming a cyanobacterial organophosphate toxin. Harmful Algae. 2020 02; 92:101737. Fiore MF, de Lima ST, Carmichael WW, McKinnie SMK, Chekan JR, Moore BS. PMID: 32113603.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    49. Cariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization. ACS Infect Dis. 2020 04 10; 6(4):563-571. Tang X, Kudo Y, Baker JL, LaBonte S, Jordan PA, McKinnie SMK, Guo J, Huan T, Moore BS, Edlund A. PMID: 31906623; PMCID: PMC7150634.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    50. Pass-back chain extension expands multimodular assembly line biosynthesis. Nat Chem Biol. 2020 01; 16(1):42-49. Zhang JJ, Tang X, Huan T, Ross AC, Moore BS. PMID: 31636431; PMCID: PMC6917876.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    51. Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage. Nat Chem. 2019 10; 11(10):880-889. Li ZR, Li J, Cai W, Lai JYH, McKinnie SMK, Zhang WP, Moore BS, Zhang W, Qian PY. PMID: 31527851; PMCID: PMC6761029.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    52. Molecular and biochemical basis for the loss of bioluminescence in the dinoflagellate Noctiluca scintillans along the west coast of the USA. Limnol Oceanogr. 2019 Nov; 64(6):2709-2724. Valiadi M, de Rond T, Amorim A, Gittins JR, Gubili C, Moore BS, Iglesias-Rodriguez MD, Latz MI. PMID: 32655189; PMCID: PMC7351363.
      View in: PubMed   Mentions: 2  
    53. Genetic platforms for heterologous expression of microbial natural products. Nat Prod Rep. 2019 09 01; 36(9):1313-1332. Zhang JJ, Tang X, Moore BS. PMID: 31197291; PMCID: PMC6750982.
      View in: PubMed   Mentions: 52     Fields:    
    54. Bacterial Tetrabromopyrrole Debrominase Shares a Reductive Dehalogenation Strategy with Human Thyroid Deiodinase. Biochemistry. 2019 12 31; 58(52):5329-5338. Chekan JR, Lee GY, El Gamal A, Purdy TN, Houk KN, Moore BS. PMID: 31117392; PMCID: PMC6872904.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    55. Comparative Genomics of Cyanobacterial Symbionts Reveals Distinct, Specialized Metabolism in Tropical Dysideidae Sponges. mBio. 2019 05 14; 10(3). Schorn MA, Jordan PA, Podell S, Blanton JM, Agarwal V, Biggs JS, Allen EE, Moore BS. PMID: 31088928; PMCID: PMC6520454.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    56. Biosynthesis of l-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide Antibiotics. Angew Chem Int Ed Engl. 2019 06 17; 58(25):8394-8399. Luhavaya H, Sigrist R, Chekan JR, McKinnie SMK, Moore BS. PMID: 30963655; PMCID: PMC6555645.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    57. Scalable Biosynthesis of the Seaweed Neurochemical, Kainic Acid. Angew Chem Int Ed Engl. 2019 06 17; 58(25):8454-8457. Chekan JR, McKinnie SMK, Moore ML, Poplawski SG, Michael TP, Moore BS. PMID: 30995339; PMCID: PMC6574125.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    58. Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives. Org Biomol Chem. 2019 03 27; 17(13):3416-3423. Rothe ML, Li J, Garibay E, Moore BS, McKinnie SMK. PMID: 30869693; PMCID: PMC6437001.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    59. Direct cloning and heterologous expression of natural product biosynthetic gene clusters by transformation-associated recombination. Methods Enzymol. 2019; 621:87-110. Zhang JJ, Yamanaka K, Tang X, Moore BS. PMID: 31128791; PMCID: PMC6555405.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    60. Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry. Cell Chem Biol. 2019 05 16; 26(5):724-736.e7. Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS. PMID: 30853419; PMCID: PMC6525064.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    61. Diversity and distribution of the bmp gene cluster and its Polybrominated products in the genus Pseudoalteromonas. Environ Microbiol. 2019 05; 21(5):1575-1585. Busch J, Agarwal V, Schorn M, Machado H, Moore BS, Rouse GW, Gram L, Jensen PR. PMID: 30652406; PMCID: PMC6491663.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    62. Enzymatic Cascade Reactions in Biosynthesis. Angew Chem Int Ed Engl. 2019 05 20; 58(21):6846-6879. Walsh CT, Moore BS. PMID: 30156048; PMCID: PMC6529181.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    63. Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein. Biochemistry. 2019 02 19; 58(7):918-929. Thapa HR, Robbins JM, Moore BS, Agarwal V. PMID: 30620182; PMCID: PMC6500386.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    64. Total Enzyme Syntheses of Napyradiomycins A1 and B1. J Am Chem Soc. 2018 12 26; 140(51):17840-17845. McKinnie SMK, Miles ZD, Jordan PA, Awakawa T, Pepper HP, Murray LAM, George JH, Moore BS. PMID: 30525563; PMCID: PMC6491662.
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    65. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep. 2019 01 01; 36(1):248-249. McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. PMID: 30468235; PMCID: PMC6474672.
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    66. The chemical cue tetrabromopyrrole induces rapid cellular stress and mortality in phytoplankton. Sci Rep. 2018 10 19; 8(1):15498. Whalen KE, Kirby C, Nicholson RM, O'Reilly M, Moore BS, Harvey EL. PMID: 30341338; PMCID: PMC6195506.
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    67. Structural Elucidation of Trace Components Combining GC/MS, GC/IR, DFT-Calculation and Synthesis-Salinilactones, Unprecedented Bicyclic Lactones from Salinispora Bacteria. Angew Chem Int Ed Engl. 2018 11 05; 57(45):14921-14925. Schlawis C, Kern S, Kudo Y, Grunenberg J, Moore BS, Schulz S. PMID: 30199596; PMCID: PMC6243141.
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    68. Pangenomic comparison of globally distributed Poribacteria associated with sponge hosts and marine particles. ISME J. 2019 02; 13(2):468-481. Podell S, Blanton JM, Neu A, Agarwal V, Biggs JS, Moore BS, Allen EE. PMID: 30291328; PMCID: PMC6331548.
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    69. Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom. Science. 2018 09 28; 361(6409):1356-1358. Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborník M, Smith GJ, Hutchins DA, Allen AE, Moore BS. PMID: 30262498; PMCID: PMC6276376.
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    70. Engineering Salinispora tropica for heterologous expression of natural product biosynthetic gene clusters. Appl Microbiol Biotechnol. 2018 Oct; 102(19):8437-8446. Zhang JJ, Moore BS, Tang X. PMID: 30105571; PMCID: PMC6139059.
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    71. Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products. Angew Chem Int Ed Engl. 2018 08 20; 57(34):11009-11014. Murray LAM, McKinnie SMK, Pepper HP, Erni R, Miles ZD, Cruickshank MC, López-Pérez B, Moore BS, George JH. PMID: 29935040; PMCID: PMC6248334.
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    72. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep. 2019 01 01; 36(1):35-107. McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. PMID: 30003207; PMCID: PMC6350634.
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    73. Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 Jul 03; 52(13):7594. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. PMID: 29916692.
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    74. Enzymatic control of dioxygen binding and functionalization of the flavin cofactor. Proc Natl Acad Sci U S A. 2018 05 08; 115(19):4909-4914. Saleem-Batcha R, Stull F, Sanders JN, Moore BS, Palfey BA, Houk KN, Teufel R. PMID: 29686059; PMCID: PMC5949001.
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    75. Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol. 2018 05 01; 52(9):5469-5478. Zheng J, McKinnie SMK, El Gamal A, Feng W, Dong Y, Agarwal V, Fenical W, Kumar A, Cao Z, Moore BS, Pessah IN. PMID: 29617551; PMCID: PMC6195434.
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    76. Characterization and Biochemical Assays of Streptomyces Vanadium-Dependent Chloroperoxidases. Methods Enzymol. 2018; 604:405-424. McKinnie SMK, Miles ZD, Moore BS. PMID: 29779661; PMCID: PMC6205230.
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    77. Preparation and Characterization of Tetrabromopyrrole Debrominase From Marine Proteobacteria. Methods Enzymol. 2018; 605:253-265. Chekan JR, Moore BS. PMID: 29909826; PMCID: PMC6211843.
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    78. Biosynthesis of the Antibiotic Bicyclomycin in Soil and Pathogenic Bacteria. Biochemistry. 2018 02 13; 57(6):897-898. Chekan JR, Moore BS. PMID: 29313351.
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    79. Natural Product Reports 35 years on. Nat Prod Rep. 2018 01 01; 35(1):6-7. Moore BS. PMID: 29367974.
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    80. Preface. Methods Enzymol. 2018; 605:xv-xvi. Moore BS. PMID: 29909840.
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    81. Preface. Methods Enzymol. 2018; 604:xv-xvi. Moore BS. PMID: 29779668.
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    82. Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster. J Antibiot (Tokyo). 2018 02; 71(2):333-338. Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS. PMID: 29184121; PMCID: PMC5960985.
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    83. Asymmetric Alkene and Arene Halofunctionalization Reactions in Meroterpenoid Biosynthesis. Synlett. 2018 Mar; 29(4):401-409. Moore BS. PMID: 31031546; PMCID: PMC6483395.
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    84. Broad-Host-Range Expression Reveals Native and Host Regulatory Elements That Influence Heterologous Antibiotic Production in Gram-Negative Bacteria. mBio. 2017 09 05; 8(5). Zhang JJ, Tang X, Zhang M, Nguyen D, Moore BS. PMID: 28874475; PMCID: PMC5587914.
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    85. Health Literacy: Cancer Prevention Strategies for Early Adults. Am J Prev Med. 2017 Sep; 53(3S1):S73-S77. Simmons RA, Cosgrove SC, Romney MC, Plumb JD, Brawer RO, Gonzalez ET, Fleisher LG, Moore BS. PMID: 28818249.
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    86. Enzymatic C-H Oxidation-Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity. Angew Chem Int Ed Engl. 2017 09 25; 56(40):12234-12239. Li J, Tang X, Awakawa T, Moore BS. PMID: 28833969; PMCID: PMC5673260.
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    87. Function-related replacement of bacterial siderophore pathways. ISME J. 2018 02; 12(2):320-329. Bruns H, Crüsemann M, Letzel AC, Alanjary M, McInerney JO, Jensen PR, Schulz S, Moore BS, Ziemert N. PMID: 28809850; PMCID: PMC5776446.
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    88. Genomic insights into specialized metabolism in the marine actinomycete Salinispora. Environ Microbiol. 2017 09; 19(9):3660-3673. Letzel AC, Li J, Amos GCA, Millán-Aguiñaga N, Ginigini J, Abdelmohsen UR, Gaudêncio SP, Ziemert N, Moore BS, Jensen PR. PMID: 28752948; PMCID: PMC5599359.
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    89. A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis. Nat Chem. 2017 12; 9(12):1235-1242. Miles ZD, Diethelm S, Pepper HP, Huang DM, George JH, Moore BS. PMID: 29168495; PMCID: PMC5960991.
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    90. Editorial: Are natural products the solution to antimicrobial resistance? Nat Prod Rep. 2017 07 01; 34(7):685-686. Moore BS, Carter GT, Brönstrup M. PMID: 28671218.
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    91. Minimization of the Thiolactomycin Biosynthetic Pathway Reveals that the Cytochrome P450 Enzyme TlmF Is Required for Five-Membered Thiolactone Ring Formation. Chembiochem. 2017 06 19; 18(12):1072-1076. Tang X, Li J, Moore BS. PMID: 28393452; PMCID: PMC5574029.
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    92. PCR-Independent Method of Transformation-Associated Recombination Reveals the Cosmomycin Biosynthetic Gene Cluster in an Ocean Streptomycete. J Nat Prod. 2017 04 28; 80(4):1200-1204. Larson CB, Crüsemann M, Moore BS. PMID: 28333450; PMCID: PMC5714584.
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    93. Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges. Nat Chem Biol. 2017 05; 13(5):537-543. Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS. PMID: 28319100; PMCID: PMC5391271.
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    94. Effects of Actinomycete Secondary Metabolites on Sediment Microbial Communities. Appl Environ Microbiol. 2017 02 15; 83(4). Patin NV, Schorn M, Aguinaldo K, Lincecum T, Moore BS, Jensen PR. PMID: 27986719; PMCID: PMC5288833.
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    95. Erratum: Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nat Microbiol. 2017 Jan 23; 2:17010. Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC. PMID: 28112718.
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    96. Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse. Chem Rev. 2017 Apr 26; 117(8):5619-5674. Agarwal V, Miles ZD, Winter JM, Eustáquio AS, El Gamal AA, Moore BS. PMID: 28106994; PMCID: PMC5575885.
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    97. Biosynthetic Pathway Connects Cryptic Ribosomally Synthesized Posttranslationally Modified Peptide Genes with Pyrroloquinoline Alkaloids. Cell Chem Biol. 2016 Dec 22; 23(12):1504-1514. Jordan PA, Moore BS. PMID: 27866908; PMCID: PMC5182094.
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    98. Family-wide Structural Characterization and Genomic Comparisons Decode the Diversity-oriented Biosynthesis of Thalassospiramides by Marine Proteobacteria. J Biol Chem. 2016 12 30; 291(53):27228-27238. Zhang W, Lu L, Lai Q, Zhu B, Li Z, Xu Y, Shao Z, Herrup K, Moore BS, Ross AC, Qian PY. PMID: 27875306; PMCID: PMC5207150.
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    99. Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols. J Nat Prod. 2017 03 24; 80(3):588-597. Crüsemann M, O'Neill EC, Larson CB, Melnik AV, Floros DJ, da Silva RR, Jensen PR, Dorrestein PC, Moore BS. PMID: 28335604; PMCID: PMC5367486.
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    100. Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nat Microbiol. 2016 10 31; 2:16197. Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC. PMID: 27798598; PMCID: PMC5538791.
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    101. Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters. Microbiology (Reading). 2016 12; 162(12):2075-2086. Schorn MA, Alanjary MM, Aguinaldo K, Korobeynikov A, Podell S, Patin N, Lincecum T, Jensen PR, Ziemert N, Moore BS. PMID: 27902408; PMCID: PMC5756490.
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    102. Enzymatic Reductive Dehalogenation Controls the Biosynthesis of Marine Bacterial Pyrroles. J Am Chem Soc. 2016 10 12; 138(40):13167-13170. El Gamal A, Agarwal V, Rahman I, Moore BS. PMID: 27676265; PMCID: PMC5201201.
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    103. Coupled Biosynthesis of Volatiles and Salinosporamide A in Salinispora tropica. Chembiochem. 2016 10 17; 17(20):1978-1985. Groenhagen U, Leandrini De Oliveira AL, Fielding E, Moore BS, Schulz S. PMID: 27490971; PMCID: PMC5179280.
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    104. Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin. Nat Chem Biol. 2016 10; 12(10):773-5. Li ZR, Li J, Gu JP, Lai JY, Duggan BM, Zhang WP, Li ZL, Li YX, Tong RB, Xu Y, Lin DH, Moore BS, Qian PY. PMID: 27547923; PMCID: PMC5030165.
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    105. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nat Biotechnol. 2016 08 09; 34(8):828-837. Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N. PMID: 27504778; PMCID: PMC5321674.
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    106. Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair. Proc Natl Acad Sci U S A. 2016 Apr 05; 113(14):3797-802. El Gamal A, Agarwal V, Diethelm S, Rahman I, Schorn MA, Sneed JM, Louie GV, Whalen KE, Mincer TJ, Noel JP, Paul VJ, Moore BS. PMID: 27001835; PMCID: PMC4833250.
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    107. A Bacterial Quorum-Sensing Precursor Induces Mortality in the Marine Coccolithophore, Emiliania huxleyi. Front Microbiol. 2016; 7:59. Harvey EL, Deering RW, Rowley DC, El Gamal A, Schorn M, Moore BS, Johnson MD, Mincer TJ, Whalen KE. PMID: 26870019; PMCID: PMC4737879.
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    108. Recent advances in the biosynthesis of unusual polyketide synthase substrates. Nat Prod Rep. 2016 Feb; 33(2):150-61. Ray L, Moore BS. PMID: 26571143; PMCID: PMC4742410.
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    109. Unusual flavoenzyme catalysis in marine bacteria. Curr Opin Chem Biol. 2016 04; 31:31-9. Teufel R, Agarwal V, Moore BS. PMID: 26803009; PMCID: PMC4870101.
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    110. A Peptidyl-Transesterifying Type I Thioesterase in Salinamide Biosynthesis. Angew Chem Int Ed Engl. 2016 Jan 04; 55(1):364-7. Ray L, Yamanaka K, Moore BS. PMID: 26553755; PMCID: PMC4715598.
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    111. Erratum: Reinvigorating natural product combinatorial biosynthesis with synthetic biology. Nat Chem Biol. 2015 Nov; 11(11):887. Kim E, Moore BS, Yoon YJ. PMID: 26485082.
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    112. Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining. ACS Chem Biol. 2015 Dec 18; 10(12):2841-2849. Tang X, Li J, Millán-Aguiñaga N, Zhang JJ, O'Neill EC, Ugalde JA, Jensen PR, Mantovani SM, Moore BS. PMID: 26458099; PMCID: PMC4758359.
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    113. Chemoenzymatic Synthesis of Acyl Coenzyme A Substrates Enables in Situ Labeling of Small Molecules and Proteins. Org Lett. 2015 Sep 18; 17(18):4452-5. Agarwal V, Diethelm S, Ray L, Garg N, Awakawa T, Dorrestein PC, Moore BS. PMID: 26333306; PMCID: PMC4720141.
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    114. Minimum Information about a Biosynthetic Gene cluster. Nat Chem Biol. 2015 Sep; 11(9):625-31. Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO. PMID: 26284661; PMCID: PMC5714517.
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    115. Reinvigorating natural product combinatorial biosynthesis with synthetic biology. Nat Chem Biol. 2015 Sep; 11(9):649-59. Kim E, Moore BS, Yoon YJ. PMID: 26284672; PMCID: PMC4757526.
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    116. Biochemical Establishment and Characterization of EncM's Flavin-N5-oxide Cofactor. J Am Chem Soc. 2015 Jul 01; 137(25):8078-85. Teufel R, Stull F, Meehan MJ, Michaudel Q, Dorrestein PC, Palfey B, Moore BS. PMID: 26067765; PMCID: PMC4720136.
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    117. Microbial and biochemical basis of a Fusarium wilt-suppressive soil. ISME J. 2016 Jan; 10(1):119-29. Cha JY, Han S, Hong HJ, Cho H, Kim D, Kwon Y, Kwon SK, Crüsemann M, Bok Lee Y, Kim JF, Giaever G, Nislow C, Moore BS, Thomashow LS, Weller DM, Kwak YS. PMID: 26057845; PMCID: PMC4681868.
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    118. Salinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase. Chembiochem. 2015 Jul 06; 16(10):1443-7. Awakawa T, Crüsemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS. PMID: 25930739; PMCID: PMC4545249.
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    119. The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery. Nat Prod Rep. 2015 May; 32(5):738-51. Jensen PR, Moore BS, Fenical W. PMID: 25730728; PMCID: PMC4414829.
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    120. Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species. Chem Biol. 2015 Apr 23; 22(4):460-471. Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen PR. PMID: 25865308; PMCID: PMC4409930.
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    121. Special issue in honor of William Fenical, a pioneer in marine natural products discovery and drug development. J Nat Prod. 2015 Mar 27; 78(3):347-8. Moore BS, Gerwick WH. PMID: 25814030.
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    122. Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis. Sci Rep. 2015 Mar 24; 5:9383. Li Y, Li Z, Yamanaka K, Xu Y, Zhang W, Vlamakis H, Kolter R, Moore BS, Qian PY. PMID: 25807046; PMCID: PMC4894447.
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    123. Mechanism of action of thalassospiramides, a new class of calpain inhibitors. Sci Rep. 2015 Mar 05; 5:8783. Lu L, Meehan MJ, Gu S, Chen Z, Zhang W, Zhang G, Liu L, Huang X, Dorrestein PC, Xu Y, Moore BS, Qian PY. PMID: 25740631; PMCID: PMC4350077.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    124. Digging for biosynthetic dark matter. Elife. 2015 Feb 13; 4:e06453. Zhang JJ, Moore BS. PMID: 25687291; PMCID: PMC4337655.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    125. Complexity of naturally produced polybrominated diphenyl ethers revealed via mass spectrometry. Environ Sci Technol. 2015 Feb 03; 49(3):1339-46. Agarwal V, Li J, Rahman I, Borgen M, Aluwihare LI, Biggs JS, Paul VJ, Moore BS. PMID: 25559102; PMCID: PMC4358748.
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    126. Sioxanthin, a novel glycosylated carotenoid, reveals an unusual subclustered biosynthetic pathway. Environ Microbiol. 2015 Jun; 17(6):2158-71. Richter TK, Hughes CC, Moore BS. PMID: 25329237; PMCID: PMC4755588.
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    127. Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin. J Nat Prod. 2015 Mar 27; 78(3):539-42. Bonet B, Teufel R, Crüsemann M, Ziemert N, Moore BS. PMID: 25382643; PMCID: PMC4380194.
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    128. Characterization of an orphan diterpenoid biosynthetic operon from Salinispora arenicola. J Nat Prod. 2014 Sep 26; 77(9):2144-7. Xu M, Hillwig ML, Lane AL, Tiernan MS, Moore BS, Peters RJ. PMID: 25203741; PMCID: PMC4176389.
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    129. Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform. ACS Synth Biol. 2015 Apr 17; 4(4):414-20. Ross AC, Gulland LE, Dorrestein PC, Moore BS. PMID: 25140825; PMCID: PMC4410906.
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    130. A multitasking vanadium-dependent chloroperoxidase as an inspiration for the chemical synthesis of the merochlorins. Angew Chem Int Ed Engl. 2014 Oct 06; 53(41):11023-6. Diethelm S, Teufel R, Kaysser L, Moore BS. PMID: 25147132; PMCID: PMC4226426.
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    131. One-pot enzymatic synthesis of merochlorin A and B. Angew Chem Int Ed Engl. 2014 Oct 06; 53(41):11019-22. Teufel R, Kaysser L, Villaume MT, Diethelm S, Carbullido MK, Baran PS, Moore BS. PMID: 25115835; PMCID: PMC4229033.
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    132. NRPquest: Coupling Mass Spectrometry and Genome Mining for Nonribosomal Peptide Discovery. J Nat Prod. 2014 Aug 22; 77(8):1902-9. Mohimani H, Liu WT, Kersten RD, Moore BS, Dorrestein PC, Pevzner PA. PMID: 25116163; PMCID: PMC4143176.
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    133. Fungal polyketide engineering comes of age. Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34):12278-9. Agarwal V, Moore BS. PMID: 25118274; PMCID: PMC4151771.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    134. Enzymatic synthesis of polybrominated dioxins from the marine environment. ACS Chem Biol. 2014 Sep 19; 9(9):1980-4. Agarwal V, Moore BS. PMID: 25061970; PMCID: PMC4168793.
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    135. Biosynthesis of polybrominated aromatic organic compounds by marine bacteria. Nat Chem Biol. 2014 Aug; 10(8):640-7. Agarwal V, El Gamal AA, Yamanaka K, Poth D, Kersten RD, Schorn M, Allen EE, Moore BS. PMID: 24974229; PMCID: PMC4104138.
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    136. Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chem Biol. 2014 Jun 19; 21(6):782-91. Trivella DB, Pereira AR, Stein ML, Kasai Y, Byrum T, Valeriote FA, Tantillo DJ, Groll M, Gerwick WH, Moore BS. PMID: 24930969; PMCID: PMC4103027.
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    137. Automated genome mining of ribosomal peptide natural products. ACS Chem Biol. 2014 Jul 18; 9(7):1545-51. Mohimani H, Kersten RD, Liu WT, Wang M, Purvine SO, Wu S, Brewer HM, Pasa-Tolic L, Bandeira N, Moore BS, Pevzner PA, Dorrestein PC. PMID: 24802639; PMCID: PMC4215869.
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    138. Antileukemic activity and mechanism of drug resistance to the marine Salinispora tropica proteasome inhibitor salinosporamide A (Marizomib). Mol Pharmacol. 2014 Jul; 86(1):12-9. Niewerth D, Jansen G, Riethoff LF, van Meerloo J, Kale AJ, Moore BS, Assaraf YG, Anderl JL, Zweegman S, Kaspers GJ, Cloos J. PMID: 24737138; PMCID: PMC4054006.
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    139. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1957-62. Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. PMID: 24449899; PMCID: PMC3918841.
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    140. Biosynthesis: Non-stick natural products. Nat Chem. 2014 Jan; 6(1):10-2. Jordan PA, Moore BS. PMID: 24345935.
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    141. Flavin-linked oxidase catalyzes pyrrolizine formation of dichloropyrrole-containing polyketide extender unit in chlorizidine A. J Am Chem Soc. 2013 Dec 04; 135(48):18032-5. Mantovani SM, Moore BS. PMID: 24246014; PMCID: PMC3887146.
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    142. Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors. ACS Chem Biol. 2014 Jan 17; 9(1):301-9. Schorn M, Zettler J, Noel JP, Dorrestein PC, Moore BS, Kaysser L. PMID: 24168704; PMCID: PMC4041076.
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    143. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4407-16. Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. PMID: 24191063; PMCID: PMC3839717.
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    144. Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement. Nature. 2013 Nov 28; 503(7477):552-556. Teufel R, Miyanaga A, Michaudel Q, Stull F, Louie G, Noel JP, Baran PS, Palfey B, Moore BS. PMID: 24162851; PMCID: PMC3844076.
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    145. MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. J Antibiot (Tokyo). 2014 Jan; 67(1):99-104. Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC. PMID: 24149839; PMCID: PMC3919142.
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    146. Challenges and triumphs to genomics-based natural product discovery. J Ind Microbiol Biotechnol. 2014 Feb; 41(2):203-9. Jensen PR, Chavarria KL, Fenical W, Moore BS, Ziemert N. PMID: 24104399; PMCID: PMC3946964.
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    147. Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics. Biochemistry. 2013 Aug 06; 52(31):5217-24. Horsman GP, Lechner A, Ohnishi Y, Moore BS, Shen B. PMID: 23844627; PMCID: PMC3849214.
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    148. MS/MS networking guided analysis of molecule and gene cluster families. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):E2611-20. Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, Kersten RD, Mehnaz S, De Mot R, Shank EA, Charusanti P, Nagarajan H, Duggan BM, Moore BS, Bandeira N, Palsson BØ, Pogliano K, Gutiérrez M, Dorrestein PC. PMID: 23798442; PMCID: PMC3710860.
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    149. A tandem chemoenzymatic methylation by S-adenosyl-L-methionine. Chembiochem. 2013 May 27; 14(8):950-3. Lipson JM, Thomsen M, Moore BS, Clausen RP, La Clair JJ, Burkart MD. PMID: 23650044; PMCID: PMC3749784.
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    150. Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica. Chembiochem. 2013 May 27; 14(8):955-62. Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS. PMID: 23649992; PMCID: PMC3755882.
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    151. Structures and comparative characterization of biosynthetic gene clusters for cyanosporasides, enediyne-derived natural products from marine actinomycetes. J Am Chem Soc. 2013 Mar 20; 135(11):4171-4. Lane AL, Nam SJ, Fukuda T, Yamanaka K, Kauffman CA, Jensen PR, Fenical W, Moore BS. PMID: 23458364; PMCID: PMC3611589.
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    152. Biosynthetic multitasking facilitates thalassospiramide structural diversity in marine bacteria. J Am Chem Soc. 2013 Jan 23; 135(3):1155-62. Ross AC, Xu Y, Lu L, Kersten RD, Shao Z, Al-Suwailem AM, Dorrestein PC, Qian PY, Moore BS. PMID: 23270364; PMCID: PMC3563429.
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    153. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep. 2013 Jan; 30(1):108-60. Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA. PMID: 23165928; PMCID: PMC3954855.
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    154. Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering. ACS Synth Biol. 2013 Jul 19; 2(7):379-83. Lechner A, Wilson MC, Ban YH, Hwang JY, Yoon YJ, Moore BS. PMID: 23654255; PMCID: PMC3716868.
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    155. Molecular mechanisms of acquired proteasome inhibitor resistance. J Med Chem. 2012 Dec 13; 55(23):10317-27. Kale AJ, Moore BS. PMID: 22978849; PMCID: PMC3521846.
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    156. Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase. Biochemistry. 2012 Oct 02; 51(39):7733-9. Qian Q, Schultz AW, Moore BS, Tanner ME. PMID: 22935004; PMCID: PMC3475536.
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    157. Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway. Chembiochem. 2012 Oct 15; 13(15):2196-9. Richter M, Busch B, Ishida K, Moore BS, Hertweck C. PMID: 22961965; PMCID: PMC3517090.
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    158. Iron acquisition in the marine actinomycete genus Salinispora is controlled by the desferrioxamine family of siderophores. FEMS Microbiol Lett. 2012 Oct; 335(2):95-103. Roberts AA, Schultz AW, Kersten RD, Dorrestein PC, Moore BS. PMID: 22812504; PMCID: PMC4209017.
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    159. Primer on agar-based microbial imaging mass spectrometry. J Bacteriol. 2012 Nov; 194(22):6023-8. Yang JY, Phelan VV, Simkovsky R, Watrous JD, Trial RM, Fleming TC, Wenter R, Moore BS, Golden SS, Pogliano K, Dorrestein PC. PMID: 22821974; PMCID: PMC3486372.
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    160. Flavoenzyme-catalyzed atropo-selective N,C-bipyrrole homocoupling in marinopyrrole biosynthesis. J Am Chem Soc. 2012 Aug 01; 134(30):12434-7. Yamanaka K, Ryan KS, Gulder TA, Hughes CC, Moore BS. PMID: 22800473; PMCID: PMC3415713.
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    161. Merochlorins A-D, cyclic meroterpenoid antibiotics biosynthesized in divergent pathways with vanadium-dependent chloroperoxidases. J Am Chem Soc. 2012 Jul 25; 134(29):11988-91. Kaysser L, Bernhardt P, Nam SJ, Loesgen S, Ruby JG, Skewes-Cox P, Jensen PR, Fenical W, Moore BS. PMID: 22784372; PMCID: PMC3410959.
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    162. Mass spectral molecular networking of living microbial colonies. Proc Natl Acad Sci U S A. 2012 Jun 26; 109(26):E1743-52. Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC. PMID: 22586093; PMCID: PMC3387089.
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    163. Bacterial biosynthesis and maturation of the didemnin anti-cancer agents. J Am Chem Soc. 2012 May 23; 134(20):8625-32. Xu Y, Kersten RD, Nam SJ, Lu L, Al-Suwailem AM, Zheng H, Fenical W, Dorrestein PC, Moore BS, Qian PY. PMID: 22458477; PMCID: PMC3401512.
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    164. The carmaphycins: new proteasome inhibitors exhibiting an α,β-epoxyketone warhead from a marine cyanobacterium. Chembiochem. 2012 Apr 16; 13(6):810-7. Pereira AR, Kale AJ, Fenley AT, Byrum T, Debonsi HM, Gilson MK, Valeriote FA, Moore BS, Gerwick WH. PMID: 22383253; PMCID: PMC3393770.
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    165. Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A. FEBS J. 2012 Apr; 279(7):1243-51. Jones AC, Ottilie S, Eustáquio AS, Edwards DJ, Gerwick L, Moore BS, Gerwick WH. PMID: 22314229.
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    166. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98. Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. PMID: 22371493; PMCID: PMC3340166.
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    167. Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. Chem Biol. 2012 Jan 27; 19(1):85-98. Gerwick WH, Moore BS. PMID: 22284357; PMCID: PMC3345185.
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    168. Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation. Chem Biol. 2011 Dec 23; 18(12):1527-36. Lechner A, Eustáquio AS, Gulder TA, Hafner M, Moore BS. PMID: 22195555; PMCID: PMC3246214.
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    169. Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity. Nat Prod Rep. 2012 Jan; 29(1):72-86. Wilson MC, Moore BS. PMID: 22124767.
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    170. Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus. J Am Chem Soc. 2011 Nov 16; 133(45):18010-3. Liu WT, Kersten RD, Yang YL, Moore BS, Dorrestein PC. PMID: 21999343; PMCID: PMC3251218.
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    171. A mass spectrometry-guided genome mining approach for natural product peptidogenomics. Nat Chem Biol. 2011 Oct 09; 7(11):794-802. Kersten RD, Yang YL, Xu Y, Cimermancic P, Nam SJ, Fenical W, Fischbach MA, Moore BS, Dorrestein PC. PMID: 21983601; PMCID: PMC3258187.
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    172. Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A. ACS Chem Biol. 2011 Nov 18; 6(11):1257-64. Kale AJ, McGlinchey RP, Lechner A, Moore BS. PMID: 21882868; PMCID: PMC3220761.
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    173. Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria. J Am Chem Soc. 2011 Aug 31; 133(34):13311-3. Miyanaga A, Janso JE, McDonald L, He M, Liu H, Barbieri L, Eustáquio AS, Fielding EN, Carter GT, Jensen PR, Feng X, Leighton M, Koehn FE, Moore BS. PMID: 21815669; PMCID: PMC3161154.
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    174. Connecting chemotypes and phenotypes of cultured marine microbial assemblages by imaging mass spectrometry. Angew Chem Int Ed Engl. 2011 Jun 20; 50(26):5839-42. Yang YL, Xu Y, Kersten RD, Liu WT, Meehan MJ, Moore BS, Bandeira N, Dorrestein PC. PMID: 21574228; PMCID: PMC3687529.
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    175. Policing starter unit selection of the enterocin type II polyketide synthase by the type II thioesterase EncL. Bioorg Med Chem. 2011 Nov 15; 19(22):6633-8. Kalaitzis JA, Cheng Q, Meluzzi D, Xiang L, Izumikawa M, Dorrestein PC, Moore BS. PMID: 21531566; PMCID: PMC3162089.
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    176. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Appl Environ Microbiol. 2011 Jun; 77(11):3617-25. Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, Gonzalez D, Liu WT, Malloy KL, Maloney KN, Nett M, Nunnery JK, Penn K, Prieto-Davo A, Simmons TL, Weitz S, Wilson MC, Tisa LS, Dorrestein PC, Moore BS. PMID: 21498757; PMCID: PMC3127629.
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    177. A stereoselective vanadium-dependent chloroperoxidase in bacterial antibiotic biosynthesis. J Am Chem Soc. 2011 Mar 30; 133(12):4268-70. Bernhardt P, Okino T, Winter JM, Miyanaga A, Moore BS. PMID: 21384874; PMCID: PMC3065929.
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    178. Structure and biosynthesis of the marine streptomycete ansamycin ansalactam A and its distinctive branched chain polyketide extender unit. J Am Chem Soc. 2011 Feb 16; 133(6):1971-7. Wilson MC, Nam SJ, Gulder TA, Kauffman CA, Jensen PR, Fenical W, Moore BS. PMID: 21247149; PMCID: PMC3091981.
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    179. The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution. Chembiochem. 2011 Jan 03; 12(1):61-4. Eustáquio AS, Nam SJ, Penn K, Lechner A, Wilson MC, Fenical W, Jensen PR, Moore BS. PMID: 21154492; PMCID: PMC3088357.
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    180. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. J Am Chem Soc. 2011 Feb 02; 133(4):976-85. Mo S, Kim DH, Lee JH, Park JW, Basnet DB, Ban YH, Yoo YJ, Chen SW, Park SR, Choi EA, Kim E, Jin YY, Lee SK, Park JY, Liu Y, Lee MO, Lee KS, Kim SJ, Kim D, Park BC, Lee SG, Kwon HJ, Suh JW, Moore BS, Lim SK, Yoon YJ. PMID: 21175203; PMCID: PMC3030623.
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    181. A sea of biosynthesis: marine natural products meet the molecular age. Nat Prod Rep. 2011 Feb; 28(2):411-28. Lane AL, Moore BS. PMID: 21170424; PMCID: PMC3101795.
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    182. Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics. Angew Chem Int Ed Engl. 2010 Dec 03; 49(49):9346-67. Gulder TA, Moore BS. PMID: 20927786; PMCID: PMC3103133.
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    183. Prephenate decarboxylases: a new prephenate-utilizing enzyme family that performs nonaromatizing decarboxylation en route to diverse secondary metabolites. Biochemistry. 2010 Oct 26; 49(42):9021-3. Mahlstedt S, Fielding EN, Moore BS, Walsh CT. PMID: 20863139; PMCID: PMC2957524.
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    184. Shared biosynthesis of the saliniketals and rifamycins in Salinispora arenicola is controlled by the sare1259-encoded cytochrome P450. J Am Chem Soc. 2010 Sep 15; 132(36):12757-65. Wilson MC, Gulder TA, Mahmud T, Moore BS. PMID: 20726561; PMCID: PMC2946249.
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    185. Characterization of 5-chloro-5-deoxy-D-ribose 1-dehydrogenase in chloroethylmalonyl coenzyme A biosynthesis: substrate and reaction profiling. J Biol Chem. 2010 Oct 29; 285(44):33710-7. Kale AJ, McGlinchey RP, Moore BS. PMID: 20736169; PMCID: PMC2962469.
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    186. Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues. J Am Chem Soc. 2010 Aug 04; 132(30):10407-13. Werneburg M, Busch B, He J, Richter ME, Xiang L, Moore BS, Roth M, Dahse HM, Hertweck C. PMID: 20662518; PMCID: PMC2925430.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    187. Richard E. Moore (1933-2007). J Nat Prod. 2010 03 26; 73(3):301-2. Cardellina JH, Moore BS. PMID: 20141160.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    188. Functional characterization of the cyclomarin/cyclomarazine prenyltransferase CymD directs the biosynthesis of unnatural cyclic peptides. J Nat Prod. 2010 Mar 26; 73(3):373-7. Schultz AW, Lewis CA, Luzung MR, Baran PS, Moore BS. PMID: 20055491; PMCID: PMC2846197.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    189. Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide. J Nat Prod. 2010 Mar 26; 73(3):378-82. Eustáquio AS, O'Hagan D, Moore BS. PMID: 20085308; PMCID: PMC2846182.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    190. Total (bio)synthesis: strategies of nature and of chemists. Top Curr Chem. 2010; 297:149-203. Roberts AA, Ryan KS, Moore BS, Gulder TA. PMID: 21495259; PMCID: PMC3109256.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    191. Mechanistic insights into water activation in SAM hydroxide adenosyltransferase (duf-62). Chembiochem. 2009 Oct 12; 10(15):2455-9. Deng H, McMahon SA, Eustáquio AS, Moore BS, Naismith JH, O'Hagan D. PMID: 19739191; PMCID: PMC3063057.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    192. Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica. J Med Chem. 2009 Oct 08; 52(19):6163-7. Nett M, Gulder TA, Kale AJ, Hughes CC, Moore BS. PMID: 19746976; PMCID: PMC2771571.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    193. Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat Prod Rep. 2009 Nov; 26(11):1362-84. Nett M, Ikeda H, Moore BS. PMID: 19844637; PMCID: PMC3063060.
      View in: PubMed   Mentions: 320     Fields:    Translation:Cells
    194. Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity. J Am Chem Soc. 2009 Aug 05; 131(30):10376-7. Liu Y, Hazzard C, Eustáquio AS, Reynolds KA, Moore BS. PMID: 19601645; PMCID: PMC2737082.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    195. Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. Proc Natl Acad Sci U S A. 2009 Jul 28; 106(30):12295-300. Eustáquio AS, McGlinchey RP, Liu Y, Hazzard C, Beer LL, Florova G, Alhamadsheh MM, Lechner A, Kale AJ, Kobayashi Y, Reynolds KA, Moore BS. PMID: 19590008; PMCID: PMC2718359.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    196. Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. Anal Chem. 2009 Jun 01; 81(11):4200-9. Liu WT, Ng J, Meluzzi D, Bandeira N, Gutierrez M, Simmons TL, Schultz AW, Linington RG, Moore BS, Gerwick WH, Pevzner PA, Dorrestein PC. PMID: 19413302; PMCID: PMC2765223.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    197. Chasing the treasures of the sea - bacterial marine natural products. Curr Opin Microbiol. 2009 Jun; 12(3):252-60. Gulder TA, Moore BS. PMID: 19481972; PMCID: PMC2695832.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    198. Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria. ISME J. 2009 Oct; 3(10):1193-203. Penn K, Jenkins C, Nett M, Udwary DW, Gontang EA, McGlinchey RP, Foster B, Lapidus A, Podell S, Allen EE, Moore BS, Jensen PR. PMID: 19474814; PMCID: PMC2749086.
      View in: PubMed   Mentions: 104     Fields:    Translation:Cells
    199. Exploring the chemistry and biology of vanadium-dependent haloperoxidases. J Biol Chem. 2009 Jul 10; 284(28):18577-81. Winter JM, Moore BS. PMID: 19363038; PMCID: PMC2707250.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    200. In vitro biosynthesis of unnatural enterocin and wailupemycin polyketides. J Nat Prod. 2009 Mar 27; 72(3):469-72. Kalaitzis JA, Cheng Q, Thomas PM, Kelleher NL, Moore BS. PMID: 19215142; PMCID: PMC2765504.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    201. Alkaloid biosynthesis takes root. Nat Chem Biol. 2009 Mar; 5(3):140-1. Ryan KS, Moore BS. PMID: 19219013.
      View in: PubMed   Mentions:    Fields:    
    202. Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone. Angew Chem Int Ed Engl. 2009; 48(4):767-70. Winter JM, Jansma AL, Handel TM, Moore BS. PMID: 19072974; PMCID: PMC3517086.
      View in: PubMed   Mentions: 25     Fields:    
    203. S-Adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archaeal protein related to SAM-dependent halogenases. Chembiochem. 2008 Sep 22; 9(14):2215-9. Eustáquio AS, Härle J, Noel JP, Moore BS. PMID: 18720493; PMCID: PMC2692205.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    204. Probing the compatibility of type II ketosynthase-carrier protein partners. Chembiochem. 2008 Sep 01; 9(13):2096-103. Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD. PMID: 18666307; PMCID: PMC2994244.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    205. Advances in and applications of proteasome inhibitors. Curr Opin Chem Biol. 2008 Aug; 12(4):434-40. Moore BS, Eustáquio AS, McGlinchey RP. PMID: 18656549; PMCID: PMC2560982.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    206. Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors. J Am Chem Soc. 2008 Jun 25; 130(25):7822-3. McGlinchey RP, Nett M, Eustáquio AS, Asolkar RN, Fenical W, Moore BS. PMID: 18512922; PMCID: PMC2814216.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    207. Biosynthesis and structures of cyclomarins and cyclomarazines, prenylated cyclic peptides of marine actinobacterial origin. J Am Chem Soc. 2008 Apr 02; 130(13):4507-16. Schultz AW, Oh DC, Carney JR, Williamson RT, Udwary DW, Jensen PR, Gould SJ, Fenical W, Moore BS. PMID: 18331040.
      View in: PubMed   Mentions: 62     Fields:    Translation:Cells
    208. Unraveling the biosynthesis of the sporolide cyclohexenone building block. J Am Chem Soc. 2008 Feb 27; 130(8):2406-7. McGlinchey RP, Nett M, Moore BS. PMID: 18232689.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    209. Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome. Angew Chem Int Ed Engl. 2008; 47(21):3936-8. Eustáquio AS, Moore BS. PMID: 18407559.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    210. Extending the biosynthetic repertoire in ribosomal peptide assembly. Angew Chem Int Ed Engl. 2008; 47(49):9386-8. Moore BS. PMID: 18846537.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    211. Discovery and characterization of a marine bacterial SAM-dependent chlorinase. Nat Chem Biol. 2008 Jan; 4(1):69-74. Eustáquio AS, Pojer F, Noel JP, Moore BS. PMID: 18059261; PMCID: PMC2762381.
      View in: PubMed   Mentions: 75     Fields:    Translation:Cells
    212. Enzymatic total synthesis of enterocin polyketides. Nat Chem Biol. 2007 Sep; 3(9):557-8. Cheng Q, Xiang L, Izumikawa M, Meluzzi D, Moore BS. PMID: 17704772.
      View in: PubMed   Mentions: 55     Fields:    
    213. Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10376-81. Udwary DW, Zeigler L, Asolkar RN, Singan V, Lapidus A, Fenical W, Jensen PR, Moore BS. PMID: 17563368; PMCID: PMC1965521.
      View in: PubMed   Mentions: 217     Fields:    Translation:Cells
    214. Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster. J Biol Chem. 2007 Jun 01; 282(22):16362-8. Winter JM, Moffitt MC, Zazopoulos E, McAlpine JB, Dorrestein PC, Moore BS. PMID: 17392281.
      View in: PubMed   Mentions: 67     Fields:    Translation:Cells
    215. Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica. Org Lett. 2007 Mar 01; 9(5):845-8. Beer LL, Moore BS. PMID: 17274624.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    216. Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization. Biochemistry. 2007 Jan 30; 46(4):1004-12. Moffitt MC, Louie GV, Bowman ME, Pence J, Noel JP, Moore BS. PMID: 17240984; PMCID: PMC2586389.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    217. Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem Biol. 2006 Dec; 13(12):1327-38. Louie GV, Bowman ME, Moffitt MC, Baiga TJ, Moore BS, Noel JP. PMID: 17185228; PMCID: PMC2859959.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    218. Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. J Am Chem Soc. 2006 Nov 22; 128(46):14754-5. Song L, Barona-Gomez F, Corre C, Xiang L, Udwary DW, Austin MB, Noel JP, Moore BS, Challis GL. PMID: 17105255; PMCID: PMC2859292.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    219. Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase. Nat Chem Biol. 2006 Sep; 2(9):494-502. Austin MB, Saito T, Bowman ME, Haydock S, Kato A, Moore BS, Kay RR, Noel JP. PMID: 16906151; PMCID: PMC2864586.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    220. Biosynthesis of marine natural products: macroorganisms (Part B). Nat Prod Rep. 2006 Aug; 23(4):615-29. Moore BS. PMID: 16874392.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    221. Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase. ACS Chem Biol. 2006 Mar 17; 1(2):93-102. Hicks LM, Moffitt MC, Beer LL, Moore BS, Kelleher NL. PMID: 17163649.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    222. Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism. J Am Chem Soc. 2006 Feb 08; 128(5):1428-9. Izumikawa M, Cheng Q, Moore BS. PMID: 16448095; PMCID: PMC2531066.
      View in: PubMed   Mentions: 13     Fields:    
    223. Biosynthesis of marine natural products: microorganisms (Part A). Nat Prod Rep. 2005 Oct; 22(5):580-93. Moore BS. PMID: 16193157.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCellsPHPublic Health
    224. Biochemical characterization of a prokaryotic phenylalanine ammonia lyase. J Bacteriol. 2005 Jun; 187(12):4286-9. Xiang L, Moore BS. PMID: 15937191; PMCID: PMC1151709.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    225. Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2. J Biol Chem. 2005 Mar 25; 280(12):11599-607. Zhao B, Guengerich FP, Bellamine A, Lamb DC, Izumikawa M, Lei L, Podust LM, Sundaramoorthy M, Kalaitzis JA, Reddy LM, Kelly SL, Moore BS, Stec D, Voehler M, Falck JR, Shimada T, Waterman MR. PMID: 15659395.
      View in: PubMed   Mentions: 59     Fields:    Translation:Cells
    226. Exploiting marine actinomycete biosynthetic pathways for drug discovery. Antonie Van Leeuwenhoek. 2005 Jan; 87(1):49-57. Moore BS, Kalaitzis JA, Xiang L. PMID: 15726291.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    227. EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15609-14. Xiang L, Kalaitzis JA, Moore BS. PMID: 15505225; PMCID: PMC524846.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    228. Engineered biosynthesis of phenyl-substituted polyketides. Chembiochem. 2004 Aug 06; 5(8):1129-31. Garcia-Bernardo J, Xiang L, Hong H, Moore BS, Leadlay PF. PMID: 15300838.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    229. Heterologous biosynthesis of truncated hexaketides derived from the actinorhodin polyketide synthase. J Nat Prod. 2004 Aug; 67(8):1419-22. Kalaitzis JA, Moore BS. PMID: 15332868.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    230. Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates. J Biol Chem. 2004 Oct 22; 279(43):45162-74. Austin MB, Izumikawa M, Bowman ME, Udwary DW, Ferrer JL, Moore BS, Noel JP. PMID: 15265863.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
    231. Context-dependent behavior of the enterocin iterative polyketide synthase; a new model for ketoreduction. Chem Biol. 2004 Apr; 11(4):461-8. Hertweck C, Xiang L, Kalaitzis JA, Cheng Q, Palzer M, Moore BS. PMID: 15123240.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    232. Cloning, sequencing, and biochemical characterization of the nostocyclopeptide biosynthetic gene cluster: molecular basis for imine macrocyclization. Gene. 2004 Jan 21; 325:35-42. Becker JE, Moore RE, Moore BS. PMID: 14697508.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    233. Biosynthesis and structural revision of neomarinone. Org Lett. 2003 Nov 13; 5(23):4449-52. Kalaitzis JA, Hamano Y, Nilsen G, Moore BS. PMID: 14602022.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    234. Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2). J Ind Microbiol Biotechnol. 2003 Aug; 30(8):510-5. Izumikawa M, Shipley PR, Hopke JN, O'Hare T, Xiang L, Noel JP, Moore BS. PMID: 12905073.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    235. Mutasynthesis of enterocin and wailupemycin analogues. J Am Chem Soc. 2003 Aug 06; 125(31):9290-1. Kalaitzis JA, Izumikawa M, Xiang L, Hertweck C, Moore BS. PMID: 12889947.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    236. Sequence analysis and biochemical characterization of the nostopeptolide A biosynthetic gene cluster from Nostoc sp. GSV224. Gene. 2003 Jun 05; 311:171-80. Hoffmann D, Hevel JM, Moore RE, Moore BS. PMID: 12853152.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    237. Characterization of benzoyl coenzyme A biosynthesis genes in the enterocin-producing bacterium "Streptomyces maritimus". J Bacteriol. 2003 Jan; 185(2):399-404. Xiang L, Moore BS. PMID: 12511484; PMCID: PMC145315.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    238. Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone. J Nat Prod. 2002 Dec; 65(12):1956-62. Moore BS, Hertweck C, Hopke JN, Izumikawa M, Kalaitzis JA, Nilsen G, O'Hare T, Piel J, Shipley PR, Xiang L, Austin MB, Noel JP. PMID: 12502351.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    239. Inactivation, complementation, and heterologous expression of encP, a novel bacterial phenylalanine ammonia-lyase gene. J Biol Chem. 2002 Sep 06; 277(36):32505-9. Xiang L, Moore BS. PMID: 12082112.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    240. Mutational analysis of the enterocin favorskii biosynthetic rearrangement. Org Lett. 2002 Mar 21; 4(6):957-60. Xiang L, Kalaitzis JA, Nilsen G, Chen L, Moore BS. PMID: 11893195.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    241. Biosynthesis and attachment of novel bacterial polyketide synthase starter units. Nat Prod Rep. 2002 Feb; 19(1):70-99. Moore BS, Hertweck C. PMID: 11902441.
      View in: PubMed   Mentions: 92     Fields:    Translation:Cells
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