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    Bing Ren

    SchoolUniversity of California, San Diego
    DepartmentCellular and Molecular Medicine
    Address9500 Gilman Drive #0653
    CA La Jolla 92093
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      Collapse Overview 
      Collapse Overview
      Our laboratory is interested in understanding how the complex gene regulatory networks in mammalian cells control cellular proliferation and differentiation. The research is divided into two general areas: 1) the development of genomics and bioinformatics tools that allow genome wide identification of regulatory targets for transcription factors; and, 2) the application of these tools to the study of transcription factors that play critical roles in cancer.

      Research Focus Areas:

    • Genetics and Genomics

    • Gene Expression and Regulation

    • Signal Transduction

    • Collapse Research 
      Collapse Research Activities and Funding
      High throughput CRISPR-mediated functional validation of regulatory elements
      NIH UM1HG009402Feb 1, 2017 - Jan 31, 2021
      Role: Principal Investigator
      San Diego Center for 4D Nucleome Research
      NIH/NIDDK U54DK107977Sep 30, 2015 - Jul 31, 2020
      Role: Principal Investigator
      The Organizational Hub and Web Portal for the 4D Nucleome Network
      NIH/NCI U01CA200147Sep 1, 2015 - Aug 31, 2020
      Role: Principal Investigator
      Non-coding Variants Predisposing to Age-related Macular Degeneration
      NIH/NHGRI R01HG008135Aug 24, 2015 - Jun 30, 2018
      Role: Principal Investigator
      Functional Analysis of T2D Associated Non-coding SNPs
      NIH/NIDDK U01DK105541May 1, 2015 - Apr 30, 2020
      Role: Principal Investigator
      Integrative Analysis of Haplotype-Resolved Human Epigenome Maps
      NIH R01ES024984Sep 8, 2014 - Aug 31, 2017
      Role: Principal Investigator
      Center for Mammalian Regulatory Genomics
      NIH U54HG006997Sep 21, 2012 - Jul 31, 2017
      Role: Principal Investigator
      The San Diego Epigenome Center
      NIH U01ES017166Sep 29, 2008 - Jun 30, 2014
      Role: Principal Investigator
      Genome-wide map of active promoters in the mouse cells
      NIH R01HG003991Sep 18, 2008 - Jul 31, 2012
      Role: Principal Investigator
      NIH R33CA105829Aug 16, 2004 - Oct 31, 2008
      Role: Principal Investigator
      NIH R21CA105829Aug 16, 2004 - Jul 31, 2005
      Role: Principal Investigator
      Mapping transcriptional regulatory elements in human DNA
      NIH U01HG003151Sep 30, 2003 - Sep 30, 2008
      Role: Principal Investigator
      Graduate Training Program in Bioinformatics
      NIH/NIGMS T32GM008806Jul 1, 2001 - Jun 30, 2021
      Role: Principal Investigator

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Yu M, Ren B. The Three-Dimensional Organization of Mammalian Genomes. Annu Rev Cell Dev Biol. 2017 Aug 07. PMID: 28783961.
        View in: PubMed
      2. Ren B, Dixon JR. A CRISPR Connection between Chromatin Topology and Genetic Disorders. Cell. 2015 May 21; 161(5):955-957. PMID: 26000472; PMCID: PMC4478077.
      3. Hawkins RD, Ren B. Genome-wide location analysis: insights on transcriptional regulation. Hum Mol Genet. 2006 Apr 15; 15 Spec No 1:R1-7. PMID: 16651365.
        View in: PubMed