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    Atul Malhotra

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9300 Campus Point Drive #7381
    CA La Jolla 92037
    Phone858-657-6159
    vCardDownload vCard

      Collapse Research 
      Collapse Research Activities and Funding
      Training in the Next Generation in Respiratory Science
      NIH T32HL134632Feb 1, 2017 - Jan 31, 2022
      Role: Principal Investigator
      Assessment of Upper Airway Mechanics Using Newer Electromyographic Techniques
      NIH K24HL132105Jun 1, 2016 - Feb 28, 2021
      Role: Principal Investigator
      Obstructive Sleep Apnea Increases Cardiovascular Risk in Type 2 Diabetes
      NIH R01HL110350Dec 1, 2011 - Jun 30, 2017
      Role: Principal Investigator
      Assessment of Upper Airway Mechanics Using Newer EMG Techniques
      NIH K24HL093218Jul 1, 2009 - Jun 30, 2014
      Role: Principal Investigator
      Mechanisms Underlying the Aging Predisposition to Obstructive Sleep Apnea
      NIH R01HL090897Jul 1, 2009 - Jun 30, 2013
      Role: Principal Investigator
      Mechanisms of Arousal in Sleep Apnea
      NIH P01HL095491Apr 1, 2009 - May 31, 2020
      Role: Co-Investigator
      Is Neuromyopathy Important in Obstructive Sleep Apnea?
      NIH R01HL085188Jul 1, 2006 - Mar 31, 2019
      Role: Principal Investigator
      Aging Influence on the Development of Sleep Apnea
      NIH K23AG024837Sep 30, 2004 - Jun 30, 2009
      Role: Principal Investigator
      Sleep Apnea and Obesity: Cardiovascular Risk Assessment
      NIH R01HL073146Sep 1, 2003 - Feb 28, 2010
      Role: Principal Investigator
      General Clinical Research Center
      NIH M01RR001032Dec 1, 1977 - Mar 31, 2010
      Role: Co-Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Landry SA, Joosten SA, Sands SA, White DP, Malhotra A, Wellman A, Hamilton GS, Edwards BA. Response to a combination of oxygen and a hypnotic as treatment for obstructive sleep apnoea is predicted by a patient's therapeutic CPAP requirement. Respirology. 2017 Apr 13. PMID: 28409851.
        View in: PubMed
      2. Hicks A, Cori JM, Jordan AS, Nicholas CL, Kubin L, Semmler JG, Malhotra A, McSharry DG, Trinder JA. Mechanisms of the deep slow-wave-sleep-related increase of upper airway muscle tone in healthy humans. J Appl Physiol (1985). 2017 Mar 02; jap.00872.2016. PMID: 28255086.
        View in: PubMed
      3. Sands SA, Mebrate Y, Edwards BA, Nemati S, Manisty CH, Desai AS, Wellman A, Willson K, Francis DP, Butler JP, Malhotra A. Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure. Am J Respir Crit Care Med. 2017 Jan 15; 195(2):237-246. PMID: 27559818.
        View in: PubMed
      4. Edwards BA, Andara C, Landry S, Sands SA, Joosten SA, Owens RL, White DP, Hamilton GS, Wellman A. Upper-Airway Collapsibility and Loop Gain Predict the Response to Oral Appliance Therapy in Patients with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2016 Dec 01; 194(11):1413-1422. PMID: 27181367.
        View in: PubMed
      5. Subramani Y, Singh M, Wong J, Kushida CA, Malhotra A, Chung F. Understanding Phenotypes of Obstructive Sleep Apnea: Applications in Anesthesia, Surgery, and Perioperative Medicine. Anesth Analg. 2016 Nov 17. PMID: 27861433.
        View in: PubMed
      6. Feliciano A, Vaz F, Torres VM, Valentim-Coelho C, Silva R, Prosinecki V, Alexandre BM, Carvalho AS, Matthiesen R, Malhotra A, Pinto P, Bárbara C, Penque D. Evening-morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters. Biochim Biophys Acta. 2016 Nov 15. PMID: 27864139.
        View in: PubMed
      7. Edwards BA, Sands SA, Owens RL, Eckert DJ, Landry S, White DP, Malhotra A, Wellman A. The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility. Sleep. 2016 Nov 1; 39(11):1973-1983. PMID: 27634790.
        View in: PubMed
      8. Li Y, Owens RL, Sands S, Orr J, Moraes W, DeYoung P, Smales E, Jen R, Malhotra A. The Effect of Donepezil on Arousal Threshold and Apnea-Hypopnea Index. A Randomized, Double-Blind, Cross-Over Study. Ann Am Thorac Soc. 2016 Nov; 13(11):2012-2018. PMID: 27442715.
        View in: PubMed
      9. Orr JE, Malhotra A, Sands SA. Pathogenesis of central and complex sleep apnoea. Respirology. 2016 Oct 31. PMID: 27797160.
        View in: PubMed
      10. Beitler JR, Malhotra A, Thompson BT. Ventilator-induced Lung Injury. Clin Chest Med. 2016 Dec; 37(4):633-646. PMID: 27842744.
        View in: PubMed
      11. Orr JE, Smales C, Alexander TH, Stepnowsky C, Pillar G, Malhotra A, Sarmiento KF. Treatment of OSA with CPAP is Associated with Improvement in PTSD Symptoms among Veterans. J Clin Sleep Med. 2016 Sep 29. PMID: 27707436.
        View in: PubMed
      12. Owens RL, Gold KA, Gozal D, Peppard PE, Jun JC, Lippman SM, Malhotra A. Sleep and Breathing … and Cancer? Cancer Prev Res (Phila). 2016 Nov; 9(11):821-827. PMID: 27604751.
        View in: PubMed
      13. Strollo PJ, Malhotra A. Stimulating therapy for obstructive sleep apnoea. Thorax. 2016 Oct; 71(10):879-80. PMID: 27488564.
        View in: PubMed
      14. Chung F, Memtsoudis SG, Ramachandran SK, Nagappa M, Opperer M, Cozowicz C, Patrawala S, Lam D, Kumar A, Joshi GP, Fleetham J, Ayas N, Collop N, Doufas AG, Eikermann M, Englesakis M, Gali B, Gay P, Hernandez AV, Kaw R, Kezirian EJ, Malhotra A, Mokhlesi B, Parthasarathy S, Stierer T, Wappler F, Hillman DR, Auckley D. Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea. Anesth Analg. 2016 Aug; 123(2):452-73. PMID: 27442772.
        View in: PubMed
      15. Tran S, Deacon N, Minokadeh A, Malhotra A, Davis DP, Villanueva S, Sell RE. Frequency and survival pattern of in-hospital cardiac arrests: The impacts of etiology and timing. Resuscitation. 2016 Oct; 107:13-8. PMID: 27456394.
        View in: PubMed
      16. Scholten EL, Beitler JR, Prisk GK, Malhotra A. Treatment of Acute Respiratory Distress Syndrome with Prone Positioning. Chest. 2016 Jul 8. PMID: 27400909.
        View in: PubMed
      17. Zaremba S, Shin CH, Hutter MM, Malviya SA, Grabitz SD, MacDonald T, Diaz-Gil D, Ramachandran SK, Hess D, Malhotra A, Eikermann M. Continuous Positive Airway Pressure Mitigates Opioid-induced Worsening of Sleep-disordered Breathing Early after Bariatric Surgery. Anesthesiology. 2016 Jul; 125(1):92-104. PMID: 27171827.
        View in: PubMed
      18. Truong KK, Lam MT, Grandner MA, Sassoon CS, Malhotra A. Timing Matters: Circadian Rhythm in Sepsis, Obstructive Lung Disease, Obstructive Sleep Apnea, and Cancer. Ann Am Thorac Soc. 2016 Jul; 13(7):1144-54. PMID: 27104378.
        View in: PubMed
      19. Malhotra A, Liang NC. Introduction: American Thoracic Society International Meeting 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S528-9. PMID: 27606083; PMCID: PMC4990682.
      20. Akrami K, Sweeney DA, Malhotra A. Antibiotic stewardship in the intensive care unit: tools for de-escalation from the American Thoracic Society Meeting 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S533-5. PMID: 27606085; PMCID: PMC4990674.
      21. Jaiswal SJ, Malhotra A, Owens RL. Sleep and critical illness: bridging the two pillars at the ATS 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S536-8. PMID: 27606086; PMCID: PMC4990683.
      22. Malhotra A, Jordan A. The importance of arousal in obstructive sleep apnea-updates from the American Thoracic Society 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S542-4. PMID: 27606088; PMCID: PMC4990689.
      23. Deacon N, Malhotra A. Potential protective mechanism of arousal in obstructive sleep apnea. J Thorac Dis. 2016 Jul; 8(Suppl 7):S545-6. PMID: 27606089; PMCID: PMC4990681.
      24. Hepokoski M, Owens RL, Malhotra A, Beitler JR. Mechanical ventilation in acute respiratory distress syndrome at ATS 2016: the search for a patient-specific strategy. J Thorac Dis. 2016 Jul; 8(Suppl 7):S550-2. PMID: 27606091; PMCID: PMC4990680.
      25. Anderson RJ, Malhotra A, Kim NH. Pulmonary hypertension: evolution of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. J Thorac Dis. 2016 Jul; 8(Suppl 7):S562-5. PMID: 27606095; PMCID: PMC4990675.
      26. Fiallo L, Malhotra A, LaBuzetta JN. A primer of neurologic emergencies: summary from the American Thoracic Society Meeting 2016. J Thorac Dis. 2016 Jul; 8(Suppl 7):S576-8. PMID: 27606099; PMCID: PMC4990677.
      27. Lam MT, Grandner MA, Malhotra A. Lungs can tell time-a highlight from 2016 ATS session on clock genes, inflammation, immunology, and sleep. J Thorac Dis. 2016 Jul; 8(Suppl 7):S579-81. PMID: 27606100; PMCID: PMC4990684.
      28. Beitler JR, Sands SA, Loring SH, Owens RL, Malhotra A, Spragg RG, Matthay MA, Thompson BT, Talmor D. Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria. Intensive Care Med. 2016 Sep; 42(9):1427-36. PMID: 27342819.
        View in: PubMed
      29. Olaithe M, Eastwood PR, Bucks RS, Deacon NL, Malhotra A, Kumar VH, Zuo L, Chuang CC, Schotland H. Commentaries on Viewpoint: Hypercapnia is more important than hypoxia in the neuro-outcomes of sleep-disordered breathing. J Appl Physiol (1985). 2016 Jun 15; 120(12):1487-8. PMID: 27306842.
        View in: PubMed
      30. Beitler JR, Owens RL, Malhotra A. Unmasking a Role for Noninvasive Ventilation in Early Acute Respiratory Distress Syndrome. JAMA. 2016 Jun 14; 315(22):2401-3. PMID: 27179463.
        View in: PubMed
      31. Jen R, Li Y, Owens RL, Malhotra A. Sleep in Chronic Obstructive Pulmonary Disease: Evidence Gaps and Challenges. Can Respir J. 2016; 2016:7947198. PMID: 27445564.
        View in: PubMed
      32. Ha D, Mazzone PJ, Ries AL, Malhotra A, Fuster M. The Utility of Exercise Testing in Patients with Lung Cancer. J Thorac Oncol. 2016 Sep; 11(9):1397-410. PMID: 27156441.
        View in: PubMed
      33. Malhotra A. Looking Back at My American Thoracic Society Presidency. Attracting and Retaining the Next Generation. Am J Respir Crit Care Med. 2016 May 1; 193(9):946-8. PMID: 27128705.
        View in: PubMed
      34. Woodell TB, Hughes-Austin JM, Tran TV, Malhotra A, Abdelmalek JA, Rifkin DE. Associations between cystatin C-based eGFR, ambulatory blood pressure parameters, and in-clinic versus ambulatory blood pressure agreement in older community-living adults. Blood Press Monit. 2016 Apr; 21(2):87-94. PMID: 26683379; NIHMSID: NIHMS736528 [Available on 04/01/17].
        View in: PubMed
      35. Sands SA, Owens RL, Malhotra A. New Approaches to Diagnosing Sleep-Disordered Breathing. Sleep Med Clin. 2016 Jun; 11(2):143-52. PMID: 27236052.
        View in: PubMed
      36. Berngard SC, Beitler JR, Malhotra A. Personalizing mechanical ventilation for acute respiratory distress syndrome. J Thorac Dis. 2016 Mar; 8(3):E172-4. PMID: 27076966.
        View in: PubMed
      37. Sweeney DA, Akrami K, Malhotra A. Improved Outcomes in Critically Ill Patients With AIDS: How Does This Trend Continue? Crit Care Med. 2016 Feb; 44(2):446-7. PMID: 26771791.
        View in: PubMed
      38. Schorr F, Kayamori F, Hirata RP, Danzi-Soares NJ, Gebrim EM, Moriya HT, Malhotra A, Lorenzi-Filho G, Genta PR. Different Craniofacial Characteristics Predict Upper Airway Collapsibility in Japanese-Brazilian and White Men. Chest. 2016 Mar; 149(3):737-46. PMID: 26291487.
        View in: PubMed
      39. Beitler JR, Majumdar R, Hubmayr RD, Malhotra A, Thompson BT, Owens RL, Loring SH, Talmor D. Volume Delivered During Recruitment Maneuver Predicts Lung Stress in Acute Respiratory Distress Syndrome. Crit Care Med. 2016 Jan; 44(1):91-9. PMID: 26474111.
        View in: PubMed
      40. Deacon NL, Jen R, Li Y, Malhotra A. Treatment of Obstructive Sleep Apnea. Prospects for Personalized Combined Modality Therapy. Ann Am Thorac Soc. 2016 Jan; 13(1):101-8. PMID: 26569377.
        View in: PubMed
      41. Orr JE, Auger WR, DeYoung PN, Kim NH, Malhotra A, Owens RL. Usefulness of Low Cardiac Index to Predict Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension. Am J Cardiol. 2016 Mar 15; 117(6):1001-5. PMID: 26805659.
        View in: PubMed
      42. Beitler JR, Guérin C, Ayzac L, Mancebo J, Bates DM, Malhotra A, Talmor D. PEEP titration during prone positioning for acute respiratory distress syndrome. Crit Care. 2015; 19:436. PMID: 26686509.
        View in: PubMed
      43. Shin W, Jen R, Li Y, Malhotra A. Tailored treatment strategies for obstructive sleep apnea. Respir Investig. 2016 Jan; 54(1):2-7. PMID: 26718138.
        View in: PubMed
      44. Phillips B, Gozal D, Malhotra A. What Is the Future of Sleep Medicine in the United States? Am J Respir Crit Care Med. 2015 Oct 15; 192(8):915-7. PMID: 26308722.
        View in: PubMed
      45. Stanchina M, Robinson K, Corrao W, Donat W, Sands S, Malhotra A. Clinical Use of Loop Gain Measures to Determine Continuous Positive Airway Pressure Efficacy in Patients with Complex Sleep Apnea. A Pilot Study. Ann Am Thorac Soc. 2015 Sep; 12(9):1351-7. PMID: 26214564.
        View in: PubMed
      46. Kohli P, Pinto-Plata V, Divo M, Malhotra A, Harris RS, Lazaar A, Flynn A, Tal-Singer R, Panettieri RA, Celli B. Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease. J Cardiopulm Rehabil Prev. 2015 Sep-Oct; 35(5):348-55. PMID: 26309192.
        View in: PubMed
      47. Soler X, Malhotra A. Reply: Sleep-Disordered Breathing in Patients with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2015 Sep; 12(9):1420-1. PMID: 26372810.
        View in: PubMed
      48. Rice MB, Malhotra A. The air we breathe and lung disease. J Thorac Dis. 2015 Aug; 7(8):E245-7. PMID: 26380790.
        View in: PubMed
      49. Donovan LM, Boeder S, Malhotra A, Patel SR. New developments in the use of positive airway pressure for obstructive sleep apnea. J Thorac Dis. 2015 Aug; 7(8):1323-42. PMID: 26380760.
        View in: PubMed
      50. Soler X, Gaio E, Powell FL, Ramsdell JW, Loredo JS, Malhotra A, Ries AL. High Prevalence of Obstructive Sleep Apnea in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2015 Aug; 12(8):1219-25. PMID: 25871443.
        View in: PubMed
      51. Crotty Alexander LE, Vyas A, Schraufnagel DE, Malhotra A. Electronic cigarettes: the new face of nicotine delivery and addiction. J Thorac Dis. 2015 Aug; 7(8):E248-51. PMID: 26380791.
        View in: PubMed
      52. Crotty Alexander L, Fuster M, Montgrain P, Malhotra A. The Need for More E-Cigarette Data: A Call to Action. Am J Respir Crit Care Med. 2015 Aug 1; 192(3):275-6. PMID: 26230232.
        View in: PubMed
      53. Ayas NT, Patil SP, Stanchina M, Malhotra A. Treatment of Central Sleep Apnea with Adaptive Servoventilation in Chronic Heart Failure. Am J Respir Crit Care Med. 2015 Jul 15; 192(2):132-3. PMID: 26082979.
        View in: PubMed
      54. Crotty Alexander LE, Malhotra A. The Civil Liberty of Smoking Cigarettes. Chest. 2015 Jul 1; 148(1):6-8. PMID: 26149548.
        View in: PubMed
      55. Altintas N, Mutlu LC, Akkoyun DC, Aydin M, Bilir B, Yilmaz A, Malhotra A. Effect of CPAP on New Endothelial Dysfunction Marker, Endocan, in People With Obstructive Sleep Apnea. Angiology. 2016 Apr; 67(4):364-74. PMID: 26076702.
        View in: PubMed
      56. Mukherjee S, Patel SR, Kales SN, Ayas NT, Strohl KP, Gozal D, Malhotra A. An Official American Thoracic Society Statement: The Importance of Healthy Sleep. Recommendations and Future Priorities. Am J Respir Crit Care Med. 2015 Jun 15; 191(12):1450-8. PMID: 26075423.
        View in: PubMed
      57. Malhotra A, Patil S, Sands S, Ayas N. Central sleep apnoea in congestive heart failure. Lancet Respir Med. 2015 Jul; 3(7):507-8. PMID: 26074186.
        View in: PubMed
      58. Owens RL, Edwards BA, Eckert DJ, Jordan AS, Sands SA, Malhotra A, White DP, Loring SH, Butler JP, Wellman A. An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy. Sleep. 2015; 38(6):961-70. PMID: 25515107.
        View in: PubMed
      59. Smales ET, Edwards BA, Deyoung PN, McSharry DG, Wellman A, Velasquez A, Owens R, Orr JE, Malhotra A. Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold. Ann Am Thorac Soc. 2015 May; 12(5):758-64. PMID: 25719754.
        View in: PubMed
      60. Beitler JR, Thompson BT, Matthay MA, Talmor D, Liu KD, Zhuo H, Hayden D, Spragg RG, Malhotra A. Estimating dead-space fraction for secondary analyses of acute respiratory distress syndrome clinical trials. Crit Care Med. 2015 May; 43(5):1026-35. PMID: 25738857.
        View in: PubMed
      61. Li Y, Daniels LB, Strollo PJ, Malhotra A. Should All Congestive Heart Failure Patients Have a Routine Sleep Apnea Screening? Con. Can J Cardiol. 2015 Jul; 31(7):940-4. PMID: 26112304.
        View in: PubMed
      62. Malhotra A, Orr JE, Owens RL. On the cutting edge of obstructive sleep apnoea: where next? Lancet Respir Med. 2015 May; 3(5):397-403. PMID: 25887980.
        View in: PubMed
      63. Corey KE, Misdraji J, Gelrud L, King LY, Zheng H, Malhotra A, Chung RT. Obstructive Sleep Apnea Is Associated with Nonalcoholic Steatohepatitis and Advanced Liver Histology. Dig Dis Sci. 2015 Aug; 60(8):2523-8. PMID: 25840922.
        View in: PubMed
      64. Kim T, Lee CS, Lee SD, Kang SH, Han JW, Malhotra A, Kim KW, Yoon IY. Impacts of Comorbidities on the Association between Arterial Stiffness and Obstructive Sleep Apnea in the Elderly. Respiration. 2015; 89(4):304-11. PMID: 25790940.
        View in: PubMed
      65. Raisinghani A, Jen R, Wilson J, Malhotra A. Obstructive Sleep Apnea Effects on the Right Ventricle and Beyond. Can J Cardiol. 2015 Jul; 31(7):821-2. PMID: 26112298.
        View in: PubMed
      66. Djonlagic I, Guo M, Matteis P, Carusona A, Stickgold R, Malhotra A. First night of CPAP: impact on memory consolidation attention and subjective experience. Sleep Med. 2015 Jun; 16(6):697-702. PMID: 25953301.
        View in: PubMed
      67. Loring SH, Malhotra A. Driving pressure and respiratory mechanics in ARDS. N Engl J Med. 2015 Feb 19; 372(8):776-7. PMID: 25693019.
        View in: PubMed
      68. Jen R, Grandner MA, Malhotra A. Future of Sleep-Disordered Breathing Therapy Using a Mechanistic Approach. Can J Cardiol. 2015 Jul; 31(7):880-8. PMID: 26044800.
        View in: PubMed
      69. Feliciano A, Torres VM, Vaz F, Carvalho AS, Matthiesen R, Pinto P, Malhotra A, Bárbara C, Penque D. Overview of proteomics studies in obstructive sleep apnea. Sleep Med. 2015 Apr; 16(4):437-45. PMID: 25770042.
        View in: PubMed
      70. Darquenne C, Hicks CB, Malhotra A. Last Word on Viewpoint: The ongoing need for good physiological investigation: Obstructive sleep apnea in HIV patients as a paradigm. J Appl Physiol (1985). 2015 Jan 15; 118(2):251. PMID: 25593221.
        View in: PubMed
      71. Edwards BA, Eckert DJ, McSharry DG, Sands SA, Desai A, Kehlmann G, Bakker JP, Genta PR, Owens RL, White DP, Wellman A, Malhotra A. Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Dec 1; 190(11):1293-300. PMID: 25321848.
        View in: PubMed
      72. Beitler JR, Awad KM, Bakker JP, Edwards BA, DeYoung P, Djonlagic I, Forman DE, Quan SF, Malhotra A. Obstructive sleep apnea is associated with impaired exercise capacity: a cross-sectional study. J Clin Sleep Med. 2014; 10(11):1199-204. PMID: 25325602.
        View in: PubMed
      73. Malhotra A, Neilan TG, Sarmiento K. Obstructive sleep apnea and atrial fibrillation: is the link real? J Am Coll Cardiol. 2014 Nov 11; 64(19):2024-5. PMID: 25440098.
        View in: PubMed
      74. Terrill PI, Edwards BA, Nemati S, Butler JP, Owens RL, Eckert DJ, White DP, Malhotra A, Wellman A, Sands SA. Quantifying the ventilatory control contribution to sleep apnoea using polysomnography. Eur Respir J. 2015 Feb; 45(2):408-18. PMID: 25323235.
        View in: PubMed
      75. Sands SA, Eckert DJ, Jordan AS, Edwards BA, Owens RL, Butler JP, Schwab RJ, Loring SH, Malhotra A, White DP, Wellman A. Enhanced Upper-Airway Muscle Responsiveness Is a Distinct Feature of Overweight/Obese Individuals without Sleep Apnea. Am J Respir Crit Care Med. 2014 Oct 15; 190(8):930-7. PMID: 25191791.
        View in: PubMed
      76. Genta PR, Schorr F, Eckert DJ, Gebrim E, Kayamori F, Moriya HT, Malhotra A, Lorenzi-Filho G. Upper airway collapsibility is associated with obesity and hyoid position. Sleep. 2014 Oct; 37(10):1673-8. PMID: 25197805.
        View in: PubMed
      77. Hubmayr RD, Malhotra A. Still Looking for Best PEEP. Anesthesiology. 2014 Sep; 121(3):445-6. PMID: 25050574.
        View in: PubMed
      78. Nemati S, Orr J, Malhotra A. Data-driven phenotyping : graphical models for model-based phenotyping of sleep apnea. IEEE Pulse. 2014 Sep-Oct; 5(5):45-8. PMID: 25437474.
        View in: PubMed
      79. Dudley KA, Malhotra A, Owens RL. Pulmonary Overlap Syndromes, with a focus on COPD and ILD. Sleep Med Clin. 2014 Sep; 9(3):365-379. PMID: 26664352.
        View in: PubMed
      80. Darquenne C, Hicks CB, Malhotra A. The ongoing need for good physiological investigation: obstructive sleep apnea in HIV patients as a paradigm. J Appl Physiol (1985). 2015 Jan 15; 118(2):244-6. PMID: 25150224.
        View in: PubMed
      81. Neilan TG, Bakker JP, Sharma B, Owens RL, Farhad H, Shah RV, Abbasi SA, Kohli P, Wilson J, DeMaria A, Jerosch-Herold M, Kwong RY, Malhotra A. T1 measurements for detection of expansion of the myocardial extracellular volume in chronic obstructive pulmonary disease. Can J Cardiol. 2014 Dec; 30(12):1668-75. PMID: 25442461.
        View in: PubMed
      82. Saboisky JP, Stashuk DW, Hamilton-Wright A, Trinder J, Nandedkar S, Malhotra A. Effects of aging on genioglossus motor units in humans. PLoS One. 2014; 9(8):e104572. PMID: 25111799.
        View in: PubMed
      83. Edwards BA, Sands SA, Owens RL, White DP, Genta PR, Butler JP, Malhotra A, Wellman A. Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea. J Physiol. 2014 Oct 15; 592(Pt 20):4523-35. PMID: 25085887.
        View in: PubMed
      84. Ayas NT, Hirsch AA, Laher I, Bradley TD, Malhotra A, Polotsky VY, Tasali E. New frontiers in obstructive sleep apnoea. Clin Sci (Lond). 2014 Aug; 127(4):209-16. PMID: 24780001.
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      85. Gederi E, Nemati S, Edwards BA, Clifford GD, Malhotra A, Wellman A. Model-based estimation of loop gain using spontaneous breathing: a validation study. Respir Physiol Neurobiol. 2014 Sep 15; 201:84-92. PMID: 25038522.
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      86. Genta PR, Owens RL, Edwards BA, Sands SA, Eckert DJ, Butler JP, Loring SH, Malhotra A, Jackson AC, White DP, Wellman A. Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway. Respir Physiol Neurobiol. 2014 Sep 15; 201:55-9. PMID: 25020212.
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      87. Edwards BA, Wellman A, Sands SA, Owens RL, Eckert DJ, White DP, Malhotra A. Obstructive Sleep Apnea in Older Adults is a Distinctly Different Physiological Phenotype. Sleep. 2014; 37(7):1227-36. PMID: 25061251.
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      88. Batool-Anwar S, Kales SN, Patel SR, Varvarigou V, DeYoung PN, Malhotra A. Obstructive sleep apnea and psychomotor vigilance task performance. Nat Sci Sleep. 2014; 6:65-71. PMID: 24920941.
        View in: PubMed
      89. Ye L, Malhotra A, Kayser K, Willis DG, Horowitz JA, Aloia MS, Weaver TE. Spousal involvement and CPAP adherence: a dyadic perspective. Sleep Med Rev. 2015 Feb; 19:67-74. PMID: 24906222; NIHMSID: NIHMS593288.
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      90. Johnson KD, Patel SR, Baur DM, Edens E, Sherry P, Malhotra A, Kales SN. Association of sleep habits with accidents and near misses in United States transportation operators. J Occup Environ Med. 2014 May; 56(5):510-5. PMID: 24806564.
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      91. Malhotra A, Deacon N, Powell F, Katz ES. Adaptive responses using obstructive sleep apnea as the paradigm. Physiology (Bethesda). 2014 May; 29(3):153-5. PMID: 24789977.
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      92. Orr J, Javaheri S, Malhotra A. Comparative effectiveness research in complex sleep apnea. Sleep. 2014; 37(5):833-4. PMID: 24790259.
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      93. Bakker JP, Edwards BA, Gautam SP, Montesi SB, Durán-Cantolla J, Barandiarán FA, Barbé F, Sánchez-de-la-Torre M, Malhotra A. Blood Pressure Improvement with Continuous Positive Airway Pressure is Independent of Obstructive Sleep Apnea Severity. J Clin Sleep Med. 2014; 10(4):365-9. PMID: 24733980.
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      94. Eckert DJ, Malhotra A, Wellman A, White DP. Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold. Sleep. 2014; 37(4):811-9. PMID: 24899767.
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      95. Zhang C, Li Y, Malhotra A, Ning Y, Gao X. Restless legs syndrome status as a predictor for lower physical function. Neurology. 2014 Apr 8; 82(14):1212-8. PMID: 24598708.
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      96. McSharry DG, Saboisky JP, Deyoung P, Jordan AS, Trinder J, Smales E, Hess L, Chamberlin NL, Malhotra A. Physiological Mechanisms of Upper Airway Hypotonia during REM Sleep. Sleep. 2014; 37(3):561-9. PMID: 24587579.
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      97. Bakker JP, Campana LM, Montesi SB, Balachandran J, Deyoung PN, Smales E, Patel SR, Malhotra A. A pilot study investigating the effects of continuous positive airway pressure treatment and weight-loss surgery on autonomic activity in obese obstructive sleep apnea patients. J Electrocardiol. 2014 May-Jun; 47(3):364-73. PMID: 24636793.
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      98. Teodorescu M, Xie A, Sorkness CA, Robbins J, Reeder S, Gong Y, Fedie JE, Sexton A, Miller B, Huard T, Hind J, Bioty N, Peterson E, Kunselman SJ, Chinchilli VM, Soler X, Ramsdell J, Loredo J, Israel E, Eckert DJ, Malhotra A. Effects of Inhaled Fluticasone on Upper Airway during Sleep and Wakefulness in Asthma: A Pilot Study. J Clin Sleep Med. 2014; 10(2):183-93. PMID: 24533002.
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      99. Eckert DJ, White DP, Jordan AS, Malhotra A, Wellman A. Reply: arousal threshold in obstructive sleep apnea. Am J Respir Crit Care Med. 2014 Feb 1; 189(3):373-4. PMID: 24484350.
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      100. Djonlagic I, Guo M, Matteis P, Carusona A, Stickgold R, Malhotra A. Untreated sleep-disordered breathing: links to aging-related decline in sleep-dependent memory consolidation. PLoS One. 2014; 9(1):e85918. PMID: 24489679.
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      101. Owens RL, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway. J Appl Physiol (1985). 2014 Apr; 116(8):1105-12. PMID: 24458746.
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      102. Beitler JR, Shaefi S, Montesi SB, Devlin A, Loring SH, Talmor D, Malhotra A. Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis. Intensive Care Med. 2014 Mar; 40(3):332-41. PMID: 24435203.
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      103. Shah RV, Abbasi SA, Heydari B, Farhad H, Dodson JA, Bakker JP, John RM, Veves A, Malhotra A, Blankstein R, Jerosch-Herold M, Kwong RY, Neilan TG. Obesity and sleep apnea are independently associated with adverse left ventricular remodeling and clinical outcome in patients with atrial fibrillation and preserved ventricular function. Am Heart J. 2014 Apr; 167(4):620-6. PMID: 24655713.
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      104. Malhotra A. Hypoglossal-nerve stimulation for obstructive sleep apnea. N Engl J Med. 2014 Jan 9; 370(2):170-1. PMID: 24401056.
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      105. Smith RS, Efron B, Mah CD, Malhotra A. The impact of circadian misalignment on athletic performance in professional football players. Sleep. 2013; 36(12):1999-2001. PMID: 24293776.
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      106. Neilan TG, Farhad H, Dodson JA, Shah RV, Abbasi SA, Bakker JP, Michaud GF, van der Geest R, Blankstein R, Steigner M, John RM, Jerosch-Herold M, Malhotra A, Kwong RY. Effect of sleep apnea and continuous positive airway pressure on cardiac structure and recurrence of atrial fibrillation. J Am Heart Assoc. 2013; 2(6):e000421. PMID: 24275628.
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      107. Montesi SB, Bakker JP, Macdonald M, Hueser L, Pittman S, White DP, Malhotra A. Air Leak during CPAP Titration as a Risk Factor for Central Apnea. J Clin Sleep Med. 2013; 9(11):1187-91. PMID: 24235901.
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      108. Deyoung PN, Bakker JP, Sands SA, Batool-Anwar S, Connolly JG, Butler JP, Malhotra A. Acoustic pharyngometry measurement of minimal cross-sectional airway area is a significant independent predictor of moderate-to-severe obstructive sleep apnea. J Clin Sleep Med. 2013; 9(11):1161-4. PMID: 24235897.
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      109. Carson SS, Goss CH, Patel SR, Anzueto A, Au DH, Elborn S, Gerald JK, Gerald LB, Kahn JM, Malhotra A, A Mularski R, A Riekert K, D Rubenfeld G, E Weaver T, Krishnan JA. An official american thoracic society research statement: comparative effectiveness research in pulmonary, critical care, and sleep medicine. Am J Respir Crit Care Med. 2013 Nov 15; 188(10):1253-61. PMID: 24160906.
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      110. Eckert DJ, White DP, Jordan AS, Malhotra A, Wellman A. Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):996-1004. PMID: 23721582.
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      111. Kezirian EJ, Goding GS, Malhotra A, O'Donoghue FJ, Zammit G, Wheatley JR, Catcheside PG, Smith PL, Schwartz AR, Walsh JH, Maddison KJ, Claman DM, Huntley T, Park SY, Campbell MC, Palme CE, Iber C, Eastwood PR, Hillman DR, Barnes M. Hypoglossal nerve stimulation improves obstructive sleep apnea: 12-month outcomes. J Sleep Res. 2014 Feb; 23(1):77-83. PMID: 24033656.
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      112. Schwab RJ, Badr SM, Epstein LJ, Gay PC, Gozal D, Kohler M, Lévy P, Malhotra A, Phillips BA, Rosen IM, Strohl KP, Strollo PJ, Weaver EM, Weaver TE. An official American Thoracic Society statement: continuous positive airway pressure adherence tracking systems. The optimal monitoring strategies and outcome measures in adults. Am J Respir Crit Care Med. 2013 Sep 1; 188(5):613-20. PMID: 23992588.
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      113. Horner RL, Hughes SW, Malhotra A. State-dependent and reflex drives to the upper airway: basic physiology with clinical implications. J Appl Physiol (1985). 2014 Feb 1; 116(3):325-36. PMID: 23970535.
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      114. Shaw ND, Goodwin JL, Silva GE, Hall JE, Quan SF, Malhotra A. Obstructive sleep apnea (OSA) in preadolescent girls is associated with delayed breast development compared to girls without OSA. J Clin Sleep Med. 2013; 9(8):813-8. PMID: 23946712.
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      115. Stanchina ML, Welicky LM, Donat W, Lee D, Corrao W, Malhotra A. Impact of CPAP use and age on mortality in patients with combined COPD and obstructive sleep apnea: the overlap syndrome. J Clin Sleep Med. 2013; 9(8):767-72. PMID: 23946706.
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      116. Jordan AS, McSharry DG, Malhotra A. Adult obstructive sleep apnoea. Lancet. 2014 Feb 22; 383(9918):736-47. PMID: 23910433.
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      117. Edwards BA, Malhotra A, Sands SA. Adapting our approach to treatment-emergent central sleep apnea. Sleep. 2013 Aug; 36(8):1121-2. PMID: 23904668.
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      118. Kaczmarek E, Bakker JP, Clarke DN, Csizmadia E, Kocher O, Veves A, Tecilazich F, O'Donnell CP, Ferran C, Malhotra A. Molecular biomarkers of vascular dysfunction in obstructive sleep apnea. PLoS One. 2013; 8(7):e70559. PMID: 23923005.
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      119. Colrain IM, Black J, Siegel LC, Bogan RK, Becker PM, Farid-Moayer M, Goldberg R, Lankford DA, Goldberg AN, Malhotra A. A multicenter evaluation of oral pressure therapy for the treatment of obstructive sleep apnea. Sleep Med. 2013 Sep; 14(9):830-7. PMID: 23871259.
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      120. Ayas NT, Malhotra A, Parthsarathy S. To sleep, or not to sleep, that is the question. Crit Care Med. 2013 Jul; 41(7):1808-10. PMID: 23774343.
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      121. Nemati S, Edwards BA, Lee J, Pittman-Polletta B, Butler JP, Malhotra A. Respiration and heart rate complexity: effects of age and gender assessed by band-limited transfer entropy. Respir Physiol Neurobiol. 2013 Oct 1; 189(1):27-33. PMID: 23811194.
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      122. Li Y, Wang W, Winkelman JW, Malhotra A, Ma J, Gao X. Prospective study of restless legs syndrome and mortality among men. Neurology. 2013 Jul 2; 81(1):52-9. PMID: 23761622.
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      123. Chervin RD, Chesson AL, Benca RM, Greenough GP, O'Hearn DJ, Auckley DH, Littner M, Mullington JM, Malhotra A, Berry RB, Malhotra RK, Schulman DA. Organization and structure for sleep medicine programs at academic institutions: part 1-current challenges. Sleep. 2013 Jun; 36(6):795-801. PMID: 23729918.
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      124. Beitler JR, Hubmayr RD, Malhotra A. CrossTalk opposing view: there is not added benefit to providing permissive hypercapnia in the treatment of ARDS. J Physiol. 2013 Jun 1; 591(Pt 11):2767-9. PMID: 23729791.
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      125. Chesson AL, Chervin RD, Benca RM, Greenough GP, O'Hearn DJ, Auckley DH, Littner M, Mullington JM, Malhotra A, Berry RB, Malhotra RK, Schulman DA. Organization and structure for sleep medicine programs at academic institutions: part 2-goals and strategies to optimize patient care, education, and discovery. Sleep. 2013 Jun; 36(6):803-11. PMID: 23729919.
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      126. Ginosar Y, Malhotra A, Schwartz E. High altitude, continuous positive airway pressure, and obstructive sleep apnea: subjective observations and objective data. High Alt Med Biol. 2013 Jun; 14(2):186-9. PMID: 23795742.
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      127. Kohli P, Sarmiento K, Malhotra A. Update in sleep medicine 2012. Am J Respir Crit Care Med. 2013 May 15; 187(10):1056-60. PMID: 23675714.
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      128. Plataki M, Sands SA, Malhotra A. Clinical consequences of altered chemoreflex control. Respir Physiol Neurobiol. 2013 Nov 1; 189(2):354-63. PMID: 23681082.
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      129. Butler JP, Owens RL, Malhotra A, Wellman A. CrossTalk opposing view: the human upper airway during sleep does not behave like a Starling resistor. J Physiol. 2013 May 1; 591(Pt 9):2233-4. PMID: 23740880.
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      130. Butler JP, Owens RL, Malhotra A, Wellman A. Rebuttal from James P. Butler, Robert L. Owens, Atul Malhotra and Andrew Wellman. J Physiol. 2013 May 1; 591(Pt 9):2237. PMID: 23740882.
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      131. Kuna ST, Benca R, Kushida CA, Walsh J, Younes M, Staley B, Hanlon A, Pack AI, Pien GW, Malhotra A. Agreement in computer-assisted manual scoring of polysomnograms across sleep centers. Sleep. 2013 Apr; 36(4):583-9. PMID: 23565004.
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      132. Malhotra A, Younes M, Kuna ST, Benca R, Kushida CA, Walsh J, Hanlon A, Staley B, Pack AI, Pien GW. Performance of an automated polysomnography scoring system versus computer-assisted manual scoring. Sleep. 2013 Apr; 36(4):573-82. PMID: 23565003.
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      133. McSharry DG, Saboisky JP, Deyoung P, Matteis P, Jordan AS, Trinder J, Smales E, Hess L, Guo M, Malhotra A. A mechanism for upper airway stability during slow wave sleep. Sleep. 2013 Apr; 36(4):555-63. PMID: 23565001.
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      134. Chang SY, Dabbagh O, Gajic O, Patrawalla A, Elie MC, Talmor DS, Malhotra A, Adesanya A, Anderson HL, Blum JM, Park PK, Gong MN. Contemporary ventilator management in patients with and at risk of ALI/ARDS. Respir Care. 2013 Apr; 58(4):578-88. PMID: 22906363.
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      135. Edwards BA, Connolly JG, Campana LM, Sands SA, Trinder JA, White DP, Wellman A, Malhotra A. Acetazolamide attenuates the ventilatory response to arousal in patients with obstructive sleep apnea. Sleep. 2013 Feb; 36(2):281-5. PMID: 23372276.
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      136. Wellman A, Edwards BA, Sands SA, Owens RL, Nemati S, Butler J, Passaglia CL, Jackson AC, Malhotra A, White DP. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. J Appl Physiol (1985). 2013 Apr; 114(7):911-22. PMID: 23349453.
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      137. Bakker JP, Montesi SB, Malhotra A. Obstructive sleep apnoea: new associations and approaches. Lancet Respir Med. 2013 Mar; 1(1):e15-6. PMID: 24321811.
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      138. Shaikh ZF, Jaye J, Ward N, Malhotra A, de Villa M, Polkey MI, Mullen MJ, Morrell MJ. Patent foramen ovale in severe obstructive sleep apnea: clinical features and effects of closure. Chest. 2013 Jan; 143(1):56-63. PMID: 22924163.
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      139. Sharma B, Neilan TG, Kwong RY, Mandry D, Owens RL, McSharry D, Bakker JP, Malhotra A. Evaluation of right ventricular remodeling using cardiac magnetic resonance imaging in co-existent chronic obstructive pulmonary disease and obstructive sleep apnea. COPD. 2013 Feb; 10(1):4-10. PMID: 23272670.
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      140. Mandelbaum T, Lee J, Scott DJ, Mark RG, Malhotra A, Howell MD, Talmor D. Empirical relationships among oliguria, creatinine, mortality, and renal replacement therapy in the critically ill. Intensive Care Med. 2013 Mar; 39(3):414-9. PMID: 23223822.
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      141. Sharma BK, Bakker JP, McSharry DG, Desai AS, Javaheri S, Malhotra A. Adaptive servoventilation for treatment of sleep-disordered breathing in heart failure: a systematic review and meta-analysis. Chest. 2012 Nov; 142(5):1211-21. PMID: 22722232.
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      142. Zhang C, Berger M, Malhotra A, Kales SN. Portable diagnostic devices for identifying obstructive sleep apnea among commercial motor vehicle drivers: considerations and unanswered questions. Sleep. 2012 Nov; 35(11):1481-9. PMID: 23115397.
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      143. Montesi SB, Edwards BA, Malhotra A, Bakker JP. The effect of continuous positive airway pressure treatment on blood pressure: a systematic review and meta-analysis of randomized controlled trials. J Clin Sleep Med. 2012 Oct 15; 8(5):587-96. PMID: 23066375.
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      144. Scheer FA, Morris CJ, Garcia JI, Smales C, Kelly EE, Marks J, Malhotra A, Shea SA. Repeated melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers: a randomized controlled trial. Sleep. 2012 Oct; 35(10):1395-402. PMID: 23024438.
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      145. Hibbert K, Rice M, Malhotra A. Obesity and ARDS. Chest. 2012 Sep; 142(3):785-90. PMID: 22948584.
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      146. Li Y, Mirzaei F, O'Reilly EJ, Winkelman J, Malhotra A, Okereke OI, Ascherio A, Gao X. Prospective study of restless legs syndrome and risk of depression in women. Am J Epidemiol. 2012 Aug 15; 176(4):279-88. PMID: 22805376.
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      147. Altintas N, Aslan E, Helvaci A, Malhotra A. Relationship between obstructive sleep apnea severity index and left ventricular function and volume. Ann Saudi Med. 2012 Jul-Aug; 32(4):384-90. PMID: 22705609.
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      148. Strohl KP, Butler JP, Malhotra A. Mechanical properties of the upper airway. Compr Physiol. 2012 Jul; 2(3):1853-72. PMID: 23723026.
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      149. Owens RL, Edwards BA, Sands SA, Butler JP, Eckert DJ, White DP, Malhotra A, Wellman A. Upper airway collapsibility and patterns of flow limitation at constant end-expiratory lung volume. J Appl Physiol (1985). 2012 Sep 1; 113(5):691-9. PMID: 22628372.
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      150. Owens RL, Campana LM, Hess L, Eckert DJ, Loring SH, Malhotra A. Sitting and supine esophageal pressures in overweight and obese subjects. Obesity (Silver Spring). 2012 Dec; 20(12):2354-60. PMID: 22695479.
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      151. Awad KM, Malhotra A, Barnet JH, Quan SF, Peppard PE. Exercise is associated with a reduced incidence of sleep-disordered breathing. Am J Med. 2012 May; 125(5):485-90. PMID: 22482846.
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      152. Nicholas CL, Jordan AS, Heckel L, Worsnop C, Bei B, Saboisky JP, Eckert DJ, White DP, Malhotra A, Trinder J. Discharge patterns of human tensor palatini motor units during sleep onset. Sleep. 2012 May; 35(5):699-707. PMID: 22547896.
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      153. Owens RL, Edwards BA, Malhotra A, Wellman A. Expiratory resistance increases end-expiratory lung volume during sleep. Am J Respir Crit Care Med. 2012 Apr 15; 185(8):e10-1. PMID: 22505761.
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      154. Lee J, Nemati S, Silva I, Edwards BA, Butler JP, Malhotra A. Transfer entropy estimation and directional coupling change detection in biomedical time series. Biomed Eng Online. 2012; 11:19. PMID: 22500692.
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      155. Djonlagic I, Saboisky J, Carusona A, Stickgold R, Malhotra A. Increased sleep fragmentation leads to impaired off-line consolidation of motor memories in humans. PLoS One. 2012; 7(3):e34106. PMID: 22470524.
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      156. Zhang C, Varvarigou V, Parks PD, Gautam S, Bueno AV, Malhotra A, Kales SN. Psychomotor vigilance testing of professional drivers in the occupational health clinic: a potential objective screen for daytime sleepiness. J Occup Environ Med. 2012 Mar; 54(3):296-302. PMID: 21826029.
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      157. Powell ED, Gay PC, Ojile JM, Litinski M, Malhotra A. A pilot study assessing adherence to auto-bilevel following a poor initial encounter with CPAP. J Clin Sleep Med. 2012 Feb 15; 8(1):43-7. PMID: 22334808.
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      158. Awad KM, Drescher AA, Malhotra A, Quan SF. Effects of exercise and nutritional intake on sleep architecture in adolescents. Sleep Breath. 2013 Mar; 17(1):117-24. PMID: 22331514.
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      159. Edwards BA, Sands SA, Eckert DJ, White DP, Butler JP, Owens RL, Malhotra A, Wellman A. Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea. J Physiol. 2012 Mar 1; 590(Pt 5):1199-211. PMID: 22219335.
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      160. Patel SR, Malhotra A, Gao X, Hu FB, Neuman MI, Fawzi WW. A prospective study of sleep duration and pneumonia risk in women. Sleep. 2012 Jan; 35(1):97-101. PMID: 22215923.
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      161. Sharma B, McSharry D, Malhotra A. Sleep disordered breathing in patients with heart failure: pathophysiology and management. Curr Treat Options Cardiovasc Med. 2011 Dec; 13(6):506-16. PMID: 21894522.
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      162. Schwartz AR, Barnes M, Hillman D, Malhotra A, Kezirian E, Smith PL, Hoegh T, Parrish D, Eastwood PR. Acute upper airway responses to hypoglossal nerve stimulation during sleep in obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 15; 185(4):420-6. PMID: 22135343.
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      163. Cao Y, McGuire M, Liu C, Malhotra A, Ling L. Phasic respiratory modulation of pharyngeal collapsibility via neuromuscular mechanisms in rats. J Appl Physiol (1985). 2012 Mar; 112(5):695-703. PMID: 22052868.
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      164. Varvarigou V, Dahabreh IJ, Malhotra A, Kales SN. A review of genetic association studies of obstructive sleep apnea: field synopsis and meta-analysis. Sleep. 2011 Nov; 34(11):1461-8. PMID: 22043116.
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      165. Eastwood PR, Barnes M, Walsh JH, Maddison KJ, Hee G, Schwartz AR, Smith PL, Malhotra A, McEvoy RD, Wheatley JR, O'Donoghue FJ, Rochford PD, Churchward T, Campbell MC, Palme CE, Robinson S, Goding GS, Eckert DJ, Jordan AS, Catcheside PG, Tyler L, Antic NA, Worsnop CJ, Kezirian EJ, Hillman DR. Treating obstructive sleep apnea with hypoglossal nerve stimulation. Sleep. 2011 Nov; 34(11):1479-86. PMID: 22043118.
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      166. Saboisky JP, Stashuk DW, Hamilton-Wright A, Carusona AL, Campana LM, Trinder J, Eckert DJ, Jordan AS, McSharry DG, White DP, Nandedkar S, David WS, Malhotra A. Neurogenic changes in the upper airway of patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 1; 185(3):322-9. PMID: 22016445.
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      167. Batool-Anwar S, Malhotra A, Forman J, Winkelman J, Li Y, Gao X. Restless legs syndrome and hypertension in middle-aged women. Hypertension. 2011 Nov; 58(5):791-6. PMID: 21986505.
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      168. Balachandran JS, Bakker JP, Rahangdale S, Yim-Yeh S, Mietus JE, Goldberger AL, Malhotra A. Effect of mild, asymptomatic obstructive sleep apnea on daytime heart rate variability and impedance cardiography measurements. Am J Cardiol. 2012 Jan 1; 109(1):140-5. PMID: 21945139.
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      169. Eckert DJ, Lo YL, Saboisky JP, Jordan AS, White DP, Malhotra A. Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea. J Appl Physiol (1985). 2011 Dec; 111(6):1644-53. PMID: 21885797.
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      170. Bertisch SM, Schomer A, Kelly EE, Baloa LA, Hueser LE, Pittman SD, Malhotra A. Device-guided paced respiration as an adjunctive therapy for hypertension in obstructive sleep apnea: a pilot feasibility study. Appl Psychophysiol Biofeedback. 2011 Sep; 36(3):173-9. PMID: 21523471.
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      171. Genta PR, Eckert DJ, Gregorio MG, Danzi NJ, Moriya HT, Malhotra A, Lorenzi-Filho G. Critical closing pressure during midazolam-induced sleep. J Appl Physiol (1985). 2011 Nov; 111(5):1315-22. PMID: 21852408.
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      172. Campana LM, Clifford GD, Trinder J, Pittman SD, Malhotra A. A possible method to predict response to non-pharmacological insomnia therapy. J Clin Sleep Med. 2011 Aug 15; 7(4):370-5. PMID: 21897773.
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      173. Jordan AS, Eckert DJ, Wellman A, Trinder JA, Malhotra A, White DP. Termination of respiratory events with and without cortical arousal in obstructive sleep apnea. Am J Respir Crit Care Med. 2011 Nov 15; 184(10):1183-91. PMID: 21836132.
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      174. Hedner J, White DP, Malhotra A, Herscovici S, Pittman SD, Zou D, Grote L, Pillar G. Sleep staging based on autonomic signals: a multi-center validation study. J Clin Sleep Med. 2011 Jun 15; 7(3):301-6. PMID: 21677901.
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      175. Eckert DJ, Owens RL, Kehlmann GB, Wellman A, Rahangdale S, Yim-Yeh S, White DP, Malhotra A. Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold. Clin Sci (Lond). 2011 Jun; 120(12):505-14. PMID: 21269278.
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      176. Rahangdale S, Yeh SY, Novack V, Stevenson K, Barnard MR, Furman MI, Frelinger AL, Michelson AD, Malhotra A. The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. J Clin Sleep Med. 2011 Apr 15; 7(2):172-8. PMID: 21509332.
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      177. Nemati S, Edwards BA, Sands SA, Berger PJ, Wellman A, Verghese GC, Malhotra A, Butler JP. Model-based characterization of ventilatory stability using spontaneous breathing. J Appl Physiol (1985). 2011 Jul; 111(1):55-67. PMID: 21474696.
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      178. Kohli P, Balachandran JS, Malhotra A. Obstructive sleep apnea and the risk for cardiovascular disease. Curr Atheroscler Rep. 2011 Apr; 13(2):138-46. PMID: 21253882.
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      179. Wellman A, Eckert DJ, Jordan AS, Edwards BA, Passaglia CL, Jackson AC, Gautam S, Owens RL, Malhotra A, White DP. A method for measuring and modeling the physiological traits causing obstructive sleep apnea. J Appl Physiol (1985). 2011 Jun; 110(6):1627-37. PMID: 21436459.
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      180. Owens RL, Wellman A, Malhotra A. Which OSA Patients Might Respond to Nasal Valves? J Clin Sleep Med. 2011 Feb 15; 7(1):23-4. PMID: 21344055.
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      181. Mostafiz W, Dalci O, Sutherland K, Malhotra A, Srinivasan V, Darendeliler MA, Cistulli PA. Influence of oral and craniofacial dimensions on mandibular advancement splint treatment outcome in patients with obstructive sleep apnea. Chest. 2011 Jun; 139(6):1331-9. PMID: 21292761.
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      182. Nemati S, Malhotra A, Clifford GD. T-wave alternans patterns during sleep in healthy, cardiac disease, and sleep apnea patients. J Electrocardiol. 2011 Mar-Apr; 44(2):126-30. PMID: 21163493.
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      183. Sharma B, Feinsilver S, Owens RL, Malhotra A, McSharry D, Karbowitz S. Obstructive airway disease and obstructive sleep apnea: effect of pulmonary function. Lung. 2011 Feb; 189(1):37-41. PMID: 21132554.
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      184. Scheer FA, Hu K, Evoniuk H, Kelly EE, Malhotra A, Hilton MF, Shea SA. Impact of the human circadian system, exercise, and their interaction on cardiovascular function. Proc Natl Acad Sci U S A. 2010 Nov 23; 107(47):20541-6. PMID: 21059915.
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      185. Nicholas CL, Bei B, Worsnop C, Malhotra A, Jordan AS, Saboisky JP, Chan JK, Duckworth E, White DP, Trinder J. Motor unit recruitment in human genioglossus muscle in response to hypercapnia. Sleep. 2010 Nov; 33(11):1529-38. PMID: 21102995.
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      186. Saboisky JP, Jordan AS, Eckert DJ, White DP, Trinder JA, Nicholas CL, Gautam S, Malhotra A. Recruitment and rate-coding strategies of the human genioglossus muscle. J Appl Physiol (1985). 2010 Dec; 109(6):1939-49. PMID: 20947713.
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      187. Edwards BA, O'Driscoll DM, Ali A, Jordan AS, Trinder J, Malhotra A. Aging and sleep: physiology and pathophysiology. Semin Respir Crit Care Med. 2010 Oct; 31(5):618-33. PMID: 20941662.
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      188. Torelli F, Moscufo N, Garreffa G, Placidi F, Romigi A, Zannino S, Bozzali M, Fasano F, Giulietti G, Djonlagic I, Malhotra A, Marciani MG, Guttmann CR. Cognitive profile and brain morphological changes in obstructive sleep apnea. Neuroimage. 2011 Jan 15; 54(2):787-93. PMID: 20888921.
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      189. Owens RL, Malhotra A. Sleep-disordered breathing and COPD: the overlap syndrome. Respir Care. 2010 Oct; 55(10):1333-44; discussion 1344-6. PMID: 20875160.
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      190. Liu C, Cao Y, Malhotra A, Ling L. Sleep fragmentation attenuates the hypercapnic (but not hypoxic) ventilatory responses via adenosine A1 receptors in awake rats. Respir Physiol Neurobiol. 2011 Jan 31; 175(1):29-36. PMID: 20833276.
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      191. Doupis J, Rahangdale S, Gnardellis C, Pena SE, Malhotra A, Veves A. Effects of diabetes and obesity on vascular reactivity, inflammatory cytokines, and growth factors. Obesity (Silver Spring). 2011 Apr; 19(4):729-35. PMID: 20829804.
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      192. Malhotra A, Owens RL. What is central sleep apnea? Respir Care. 2010 Sep; 55(9):1168-78. PMID: 20799999.
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      193. Yim-Yeh S, Rahangdale S, Nguyen AT, Jordan AS, Novack V, Veves A, Malhotra A. Obstructive sleep apnea and aging effects on macrovascular and microcirculatory function. Sleep. 2010 Sep; 33(9):1177-83. PMID: 20857864.
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      194. Krystal AD, Zammit GK, Wyatt JK, Quan SF, Edinger JD, White DP, Chiacchierini RP, Malhotra A. The effect of vestibular stimulation in a four-hour sleep phase advance model of transient insomnia. J Clin Sleep Med. 2010 Aug 15; 6(4):315-21. PMID: 20726278.
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      195. Djonlagic I, Malhotra A. Risk of stroke from sleep apnea in men and women. Expert Rev Neurother. 2010 Aug; 10(8):1267-71. PMID: 20662752.
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      196. Kezirian EJ, Malhotra A, Goldberg AN, White DP. Changes in obstructive sleep apnea severity, biomarkers, and quality of life after multilevel surgery. Laryngoscope. 2010 Jul; 120(7):1481-8. PMID: 20564750.
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      197. Yim-Yeh S, Rahangdale S, Nguyen AT, Stevenson KE, Novack V, Veves A, Malhotra A. Vascular dysfunction in obstructive sleep apnea and type 2 diabetes mellitus. Obesity (Silver Spring). 2011 Jan; 19(1):17-22. PMID: 20523303.
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      198. Gladysheva ES, Malhotra A, Owens RL. Influencing the decline of lung function in COPD: use of pharmacotherapy. Int J Chron Obstruct Pulmon Dis. 2010; 5:153-64. PMID: 20631815.
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      199. Jordan AS, White DP, Owens RL, Eckert DJ, Rahangdale S, Yim-Yeh S, Malhotra A. The effect of increased genioglossus activity and end-expiratory lung volume on pharyngeal collapse. J Appl Physiol (1985). 2010 Aug; 109(2):469-75. PMID: 20507968.
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      200. Sharma B, Owens R, Malhotra A. Sleep in congestive heart failure. Med Clin North Am. 2010 May; 94(3):447-64. PMID: 20451026.
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      201. Eckert DJ, Saboisky JP, Jordan AS, White DP, Malhotra A. A secondary reflex suppression phase is present in genioglossus but not tensor palatini in response to negative upper airway pressure. J Appl Physiol (1985). 2010 Jun; 108(6):1619-24. PMID: 20378702.
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      202. Kezirian EJ, White DP, Malhotra A, Ma W, McCulloch CE, Goldberg AN. Interrater reliability of drug-induced sleep endoscopy. Arch Otolaryngol Head Neck Surg. 2010 Apr; 136(4):393-7. PMID: 20403857.
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      203. Wilkinson V, Malhotra A, Nicholas CL, Worsnop C, Jordan AS, Butler JE, Saboisky JP, Gandevia SC, White DP, Trinder J. Discharge patterns of human genioglossus motor units during arousal from sleep. Sleep. 2010 Mar; 33(3):379-87. PMID: 20337197.
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      204. Campana L, Eckert DJ, Patel SR, Malhotra A. Pathophysiology & genetics of obstructive sleep apnoea. Indian J Med Res. 2010 Feb; 131:176-87. PMID: 20308743.
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      205. Eastwood PR, Malhotra A, Palmer LJ, Kezirian EJ, Horner RL, Ip MS, Thurnheer R, Antic NA, Hillman DR. Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions. Respirology. 2010 May; 15(4):587-95. PMID: 20136736.
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      206. Loring SH, O'Donnell CR, Behazin N, Malhotra A, Sarge T, Ritz R, Novack V, Talmor D. Esophageal pressures in acute lung injury: do they represent artifact or useful information about transpulmonary pressure, chest wall mechanics, and lung stress? J Appl Physiol (1985). 2010 Mar; 108(3):515-22. PMID: 20019160.
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      207. Owens RL, Malhotra A, Eckert DJ, White DP, Jordan AS. The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility. J Appl Physiol (1985). 2010 Feb; 108(2):445-51. PMID: 19940097.
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      208. Owens RL, Harris RS, Malhotra A. Is the way to man's heart (and lung) through the abdomen? Crit Care. 2009; 13(6):199. PMID: 19909491.
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      209. Owens R, Wellman A, Malhotra A. The chicken-or-egg debate in OSA pathogenesis. Sleep. 2009 Oct; 32(10):1255-6. PMID: 19848354.
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      210. Saboisky JP, Chamberlin NL, Malhotra A. Potential therapeutic targets in obstructive sleep apnoea. Expert Opin Ther Targets. 2009 Jul; 13(7):795-809. PMID: 19530985.
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      211. Epstein LJ, Kristo D, Strollo PJ, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med. 2009 Jun 15; 5(3):263-76. PMID: 19960649.
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      212. Eikermann M, Fassbender P, Zaremba S, Jordan AS, Rosow C, Malhotra A, Chamberlin NL. Pentobarbital dose-dependently increases respiratory genioglossus muscle activity while impairing diaphragmatic function in anesthetized rats. Anesthesiology. 2009 Jun; 110(6):1327-34. PMID: 19417601.
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      213. Yeh SY, Doupis J, Rahangdale S, Horr S, Malhotra A, Veves A. Total serum bilirubin does not affect vascular reactivity in patients with diabetes. Vasc Med. 2009 May; 14(2):129-36. PMID: 19366819.
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      214. Loring SH, Garcia-Jacques M, Malhotra A. Pulmonary characteristics in COPD and mechanisms of increased work of breathing. J Appl Physiol (1985). 2009 Jul; 107(1):309-14. PMID: 19359620.
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      215. Jordan AS, White DP, Lo YL, Wellman A, Eckert DJ, Yim-Yeh S, Eikermann M, Smith SA, Stevenson KE, Malhotra A. Airway dilator muscle activity and lung volume during stable breathing in obstructive sleep apnea. Sleep. 2009 Mar; 32(3):361-8. PMID: 19294956.
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      216. Atkeson A, Yeh SY, Malhotra A, Jelic S. Endothelial function in obstructive sleep apnea. Prog Cardiovasc Dis. 2009 Mar-Apr; 51(5):351-62. PMID: 19249441.
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      217. Malhotra A, Loscalzo J. Sleep and cardiovascular disease: an overview. Prog Cardiovasc Dis. 2009 Jan-Feb; 51(4):279-84. PMID: 19110129.
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      218. Rahangdale S, Yeh SY, Malhotra A, Veves A. Therapeutic interventions and oxidative stress in diabetes. Front Biosci (Landmark Ed). 2009; 14:192-209. PMID: 19273063.
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      219. Eckert DJ, Malhotra A, Jordan AS. Mechanisms of apnea. Prog Cardiovasc Dis. 2009 Jan-Feb; 51(4):313-23. PMID: 19110133.
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      220. Eckert DJ, Malhotra A, Lo YL, White DP, Jordan AS. The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep. Chest. 2009 Apr; 135(4):957-64. PMID: 19118266.
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      221. Owens RL, Eckert DJ, Yeh SY, Malhotra A. Upper airway function in the pathogenesis of obstructive sleep apnea: a review of the current literature. Curr Opin Pulm Med. 2008 Nov; 14(6):519-24. PMID: 18812828.
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      222. Owens RL, Hess DR, Malhotra A, Venegas JG, Harris RS. Effect of the chest wall on pressure-volume curve analysis of acute respiratory distress syndrome lungs. Crit Care Med. 2008 Nov; 36(11):2980-5. PMID: 18824918.
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      223. Owens RL, Yim-Yeh S, Malhotra A. Carbon monoxide poisoning, or carbon monoxide protection? Chest. 2008 Nov; 134(5):895-6. PMID: 18988771.
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      224. Malhotra A, Bertisch S, Wellman A. Complex sleep apnea: it isn't really a disease. J Clin Sleep Med. 2008 Oct 15; 4(5):406-8. PMID: 18853695.
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      225. Yeh SY, Rahangdale S, Malhotra A. Metabolic syndrome, obstructive sleep apnea, and continuous positive airway pressure: a weighty issue. Chest. 2008 Oct; 134(4):675-6. PMID: 18842905.
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      226. Rahangdale S, Campana L, Malhotra A. Not so good vibrations. Commentary on Lee et al. Heavy snoring as a cause of carotid artery atherosclerosis. SLEEP 2008;31(9):1207-1213. Sleep. 2008 Sep; 31(9):1204-5. PMID: 18788644.
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      227. Wellman A, Malhotra A, Jordan AS, Stevenson KE, Gautam S, White DP. Effect of oxygen in obstructive sleep apnea: role of loop gain. Respir Physiol Neurobiol. 2008 Jul 31; 162(2):144-51. PMID: 18577470.
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      228. Segal Y, Malhotra A, Pillar G. Upper airway length may be associated with the severity of obstructive sleep apnea syndrome. Sleep Breath. 2008 Nov; 12(4):311-6. PMID: 18516636.
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      229. Eikermann M, Malhotra A, Fassbender P, Zaremba S, Jordan AS, Gautam S, White DP, Chamberlin NL. Differential effects of isoflurane and propofol on upper airway dilator muscle activity and breathing. Anesthesiology. 2008 May; 108(5):897-906. PMID: 18431126.
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      230. Wilkinson V, Malhotra A, Nicholas CL, Worsnop C, Jordan AS, Butler JE, Saboisky JP, Gandevia SC, White DP, Trinder J. Discharge patterns of human genioglossus motor units during sleep onset. Sleep. 2008 Apr; 31(4):525-33. PMID: 18457240.
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      231. Heinzer R, White DP, Malhotra A, Lo YL, Dover L, Stevenson KE, Jordan AS. Effect of expiratory positive airway pressure on sleep disordered breathing. Sleep. 2008 Mar; 31(3):429-32. PMID: 18363320.
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      232. Eckert DJ, Malhotra A. Pathophysiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008 Feb 15; 5(2):144-53. PMID: 18250206.
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      233. MacDonald M, Fang J, Pittman SD, White DP, Malhotra A. The current prevalence of sleep disordered breathing in congestive heart failure patients treated with beta-blockers. J Clin Sleep Med. 2008 Feb 15; 4(1):38-42. PMID: 18350960.
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      234. Caramez MP, Miyoshi E, Harris RS, Kacmarek RM, Malhotra A. Gas exchange impairment induced by open suctioning in acute respiratory distress syndrome: impact of permissive hypercapnia. Crit Care Med. 2008 Feb; 36(2):560-4. PMID: 18091534.
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      235. Eckert DJ, Saboisky JP, Jordan AS, Malhotra A. Upper airway myopathy is not important in the pathophysiology of obstructive sleep apnea. J Clin Sleep Med. 2007 Oct 15; 3(6):570-3. PMID: 17993036.
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      236. Eikermann M, Fassbender P, Malhotra A, Takahashi M, Kubo S, Jordan AS, Gautam S, White DP, Chamberlin NL. Unwarranted administration of acetylcholinesterase inhibitors can impair genioglossus and diaphragm muscle function. Anesthesiology. 2007 Oct; 107(4):621-9. PMID: 17893459.
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      237. Malhotra A. Low-tidal-volume ventilation in the acute respiratory distress syndrome. N Engl J Med. 2007 Sep 13; 357(11):1113-20. PMID: 17855672.
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      238. Stanchina ML, Ellison K, Malhotra A, Anderson M, Kirk M, Benser ME, Tosi C, Carlisle C, Millman RP, Buxton A. The impact of cardiac resynchronization therapy on obstructive sleep apnea in heart failure patients: a pilot study. Chest. 2007 Aug; 132(2):433-9. PMID: 17573498.
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      239. Eikermann M, Jordan AS, Chamberlin NL, Gautam S, Wellman A, Lo YL, White DP, Malhotra A. The influence of aging on pharyngeal collapsibility during sleep. Chest. 2007 Jun; 131(6):1702-9. PMID: 17413053.
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      240. Jordan AS, Wellman A, Heinzer RC, Lo YL, Schory K, Dover L, Gautam S, Malhotra A, White DP. Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans. Thorax. 2007 Oct; 62(10):861-7. PMID: 17412778.
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      241. Huang Y, White DP, Malhotra A. Use of computational modeling to predict responses to upper airway surgery in obstructive sleep apnea. Laryngoscope. 2007 Apr; 117(4):648-53. PMID: 17415135.
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      242. Lo YL, Jordan AS, Malhotra A, Wellman A, Heinzer RA, Eikermann M, Schory K, Dover L, White DP. Influence of wakefulness on pharyngeal airway muscle activity. Thorax. 2007 Sep; 62(9):799-805. PMID: 17389755.
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      243. Wellman A, Malhotra A, Jordan AS, Schory K, Gautam S, White DP. Chemical control stability in the elderly. J Physiol. 2007 May 15; 581(Pt 1):291-8. PMID: 17317747.
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      244. Eckert DJ, Jordan AS, Merchia P, Malhotra A. Central sleep apnea: Pathophysiology and treatment. Chest. 2007 Feb; 131(2):595-607. PMID: 17296668.
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      245. Chamberlin NL, Eikermann M, Fassbender P, White DP, Malhotra A. Genioglossus premotoneurons and the negative pressure reflex in rats. J Physiol. 2007 Mar 1; 579(Pt 2):515-26. PMID: 17185342.
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      246. Pittman SD, Pillar G, Berry RB, Malhotra A, MacDonald MM, White DP. Follow-up assessment of CPAP efficacy in patients with obstructive sleep apnea using an ambulatory device based on peripheral arterial tonometry. Sleep Breath. 2006 Sep; 10(3):123-31. PMID: 16586136.
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      247. Patel SR, Malhotra A, White DP, Gottlieb DJ, Hu FB. Association between reduced sleep and weight gain in women. Am J Epidemiol. 2006 Nov 15; 164(10):947-54. PMID: 16914506.
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      248. Patel SR, Malhotra A, Gottlieb DJ, White DP, Hu FB. Correlates of long sleep duration. Sleep. 2006 Jul; 29(7):881-9. PMID: 16895254.
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      249. Caramez MP, Schettino G, Suchodolski K, Nishida T, Harris RS, Malhotra A, Kacmarek RM. The impact of endotracheal suctioning on gas exchange and hemodynamics during lung-protective ventilation in acute respiratory distress syndrome. Respir Care. 2006 May; 51(5):497-502. PMID: 16638159.
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      250. Talmor D, Sarge T, O'Donnell CR, Ritz R, Malhotra A, Lisbon A, Loring SH. Esophageal and transpulmonary pressures in acute respiratory failure. Crit Care Med. 2006 May; 34(5):1389-94. PMID: 16540960.
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      251. Lo YL, Jordan AS, Malhotra A, Wellman A, Heinzer RC, Schory K, Dover L, Fogel RB, White DP. Genioglossal muscle response to CO2 stimulation during NREM sleep. Sleep. 2006 Apr; 29(4):470-7. PMID: 16676780.
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      252. Malhotra A, Huang Y, Fogel R, Lazic S, Pillar G, Jakab M, Kikinis R, White DP. Aging influences on pharyngeal anatomy and physiology: the predisposition to pharyngeal collapse. Am J Med. 2006 Jan; 119(1):72.e9-14. PMID: 16431197.
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      253. Malhotra A, Jordan AS. Did fat boy Joe need hormone replacement? Sleep. 2006 Jan; 29(1):16-8. PMID: 16453975.
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      254. Malhotra A, Patel S. Lung biopsy in ARDS: is it worth the risk? Crit Care. 2006; 10(4):160. PMID: 16941755.
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      255. Huang Y, White DP, Malhotra A. The impact of anatomic manipulations on pharyngeal collapse: results from a computational model of the normal human upper airway. Chest. 2005 Sep; 128(3):1324-30. PMID: 16162725.
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      256. Jordan A, Malhotra A. The pharyngeal lumen: both length and size matter. J Clin Sleep Med. 2005 Jul 15; 1(3):264-5. PMID: 17566186.
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      257. Bajwa EK, Ayas NT, Schulzer M, Mak E, Ryu JH, Malhotra A. Interferon-gamma1b therapy in idiopathic pulmonary fibrosis: a metaanalysis. Chest. 2005 Jul; 128(1):203-6. PMID: 16002936.
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      258. Jordan AS, Wellman A, Edwards JK, Schory K, Dover L, MacDonald M, Patel SR, Fogel RB, Malhotra A, White DP. Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea. J Appl Physiol (1985). 2005 Nov; 99(5):2020-7. PMID: 15994243.
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      259. Ting L, Malhotra A. Disorders of sleep: an overview. Prim Care. 2005 Jun; 32(2):305-18, v. PMID: 15935187.
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      260. Aloia MS, Stanchina M, Arnedt JT, Malhotra A, Millman RP. Treatment adherence and outcomes in flexible vs standard continuous positive airway pressure therapy. Chest. 2005 Jun; 127(6):2085-93. PMID: 15947324.
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      261. Huang Y, Malhotra A, White DP. Computational simulation of human upper airway collapse using a pressure-/state-dependent model of genioglossal muscle contraction under laminar flow conditions. J Appl Physiol (1985). 2005 Sep; 99(3):1138-48. PMID: 15831800.
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      262. Heinzer RC, Stanchina ML, Malhotra A, Fogel RB, Patel SR, Jordan AS, Schory K, White DP. Lung volume and continuous positive airway pressure requirements in obstructive sleep apnea. Am J Respir Crit Care Med. 2005 Jul 1; 172(1):114-7. PMID: 15817803.
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      263. Malhotra A, Jordan A. Surface tension and sleep apnea: a sticky business. Sleep. 2005 Apr; 28(4):392-3. PMID: 16171283.
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      264. Fogel RB, Trinder J, White DP, Malhotra A, Raneri J, Schory K, Kleverlaan D, Pierce RJ. The effect of sleep onset on upper airway muscle activity in patients with sleep apnoea versus controls. J Physiol. 2005 Apr 15; 564(Pt 2):549-62. PMID: 15695240.
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      265. Bajwa EK, Malhotra A, Thompson BT. Methods of monitoring shock. Semin Respir Crit Care Med. 2004 Dec; 25(6):629-44. PMID: 16088506.
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      266. Pittman SD, MacDonald MM, Fogel RB, Malhotra A, Todros K, Levy B, Geva AB, White DP. Assessment of automated scoring of polysomnographic recordings in a population with suspected sleep-disordered breathing. Sleep. 2004 Nov 1; 27(7):1394-403. PMID: 15586793.
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      267. Malhotra A, Trinder J, Fogel R, Stanchina M, Patel SR, Schory K, Kleverlaan D, White DP. Postural effects on pharyngeal protective reflex mechanisms. Sleep. 2004 Sep 15; 27(6):1105-12. PMID: 15532204.
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      268. Wellman A, Jordan AS, Malhotra A, Fogel RB, Katz ES, Schory K, Edwards JK, White DP. Ventilatory control and airway anatomy in obstructive sleep apnea. Am J Respir Crit Care Med. 2004 Dec 1; 170(11):1225-32. PMID: 15317668.
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      269. Pittman SD, Ayas NT, MacDonald MM, Malhotra A, Fogel RB, White DP. Using a wrist-worn device based on peripheral arterial tonometry to diagnose obstructive sleep apnea: in-laboratory and ambulatory validation. Sleep. 2004 Aug 1; 27(5):923-33. PMID: 15453551.
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      270. Jordan AS, McEvoy RD, Edwards JK, Schory K, Yang CK, Catcheside PG, Fogel RB, Malhotra A, White DP. The influence of gender and upper airway resistance on the ventilatory response to arousal in obstructive sleep apnoea in humans. J Physiol. 2004 Aug 1; 558(Pt 3):993-1004. PMID: 15218069.
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      271. Ayas NT, Patel SR, Malhotra A, Schulzer M, Malhotra M, Jung D, Fleetham J, White DP. Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: results of a meta-analysis. Sleep. 2004 Mar 15; 27(2):249-53. PMID: 15124718.
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      272. Patel SR, Karmpaliotis D, Ayas NT, Mark EJ, Wain J, Thompson BT, Malhotra A. The role of open-lung biopsy in ARDS. Chest. 2004 Jan; 125(1):197-202. PMID: 14718441.
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      273. Carden K, Malhotra A. The debate about gender differences in obstructive sleep apnea. Sleep Med. 2003 Nov; 4(6):485-7. PMID: 14607341.
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      274. Stanchina ML, Malhotra A, Fogel RB, Trinder J, Edwards JK, Schory K, White DP. The influence of lung volume on pharyngeal mechanics, collapsibility, and genioglossus muscle activation during sleep. Sleep. 2003 Nov 1; 26(7):851-6. PMID: 14655919.
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      275. Fogel RB, White DP, Pierce RJ, Malhotra A, Edwards JK, Dunai J, Kleverlaan D, Trinder J. Control of upper airway muscle activity in younger versus older men during sleep onset. J Physiol. 2003 Dec 1; 553(Pt 2):533-44. PMID: 12963804.
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      276. Fogel RB, Trinder J, Malhotra A, Stanchina M, Edwards JK, Schory KE, White DP. Within-breath control of genioglossal muscle activation in humans: effect of sleep-wake state. J Physiol. 2003 Aug 1; 550(Pt 3):899-910. PMID: 12807995.
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      277. Malhotra A, Muse VV, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 12-2003. An 82-year-old man with dyspnea and pulmonary abnormalities. N Engl J Med. 2003 Apr 17; 348(16):1574-85. PMID: 12700378.
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      278. Fogel RB, Malhotra A, Dalagiorgou G, Robinson MK, Jakab M, Kikinis R, Pittman SD, White DP. Anatomic and physiologic predictors of apnea severity in morbidly obese subjects. Sleep. 2003 Mar 15; 26(2):150-5. PMID: 12683472.
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      279. Patel SR, White DP, Malhotra A, Stanchina ML, Ayas NT. Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysis. Arch Intern Med. 2003 Mar 10; 163(5):565-71. PMID: 12622603.
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      280. Ayas NT, White DP, Manson JE, Stampfer MJ, Speizer FE, Malhotra A, Hu FB. A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med. 2003 Jan 27; 163(2):205-9. PMID: 12546611.
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      281. Berry RB, White DP, Roper J, Pillar G, Fogel RB, Stanchina M, Malhotra A. Awake negative pressure reflex response of the genioglossus in OSA patients and normal subjects. J Appl Physiol (1985). 2003 May; 94(5):1875-82. PMID: 12533492.
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      282. Malhotra A, Huang Y, Fogel RB, Pillar G, Edwards JK, Kikinis R, Loring SH, White DP. The male predisposition to pharyngeal collapse: importance of airway length. Am J Respir Crit Care Med. 2002 Nov 15; 166(10):1388-95. PMID: 12421747.
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      283. Wellman A, Malhotra A, Fogel RB, Edwards JK, Schory K, White DP. Respiratory system loop gain in normal men and women measured with proportional-assist ventilation. J Appl Physiol (1985). 2003 Jan; 94(1):205-12. PMID: 12391042.
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      284. Karmpaliotis D, Kosmidou I, Ingenito EP, Hong K, Malhotra A, Sunday ME, Haley KJ. Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2002 Sep; 283(3):L585-95. PMID: 12169578.
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      285. Wellman A, Malhotra A, White DP. Atrial pacing in sleep apnea syndrome. N Engl J Med. 2002 Aug 8; 347(6):445-6; author reply 445-6. PMID: 12167690.
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      286. Malhotra A, White DP. Obstructive sleep apnoea. Lancet. 2002 Jul 20; 360(9328):237-45. PMID: 12133673.
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      287. Stanchina ML, Malhotra A, Fogel RB, Ayas N, Edwards JK, Schory K, White DP. Genioglossus muscle responsiveness to chemical and mechanical stimuli during non-rapid eye movement sleep. Am J Respir Crit Care Med. 2002 Apr 1; 165(7):945-9. PMID: 11934719.
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      288. Malhotra A, Ayas N, Kacmarek R. Prone positioning of patients in acute respiratory failure. N Engl J Med. 2002 Jan 24; 346(4):295-7. PMID: 11811184.
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      289. Malhotra A, Pillar G, Fogel RB, Edwards JK, Ayas N, Akahoshi T, Hess D, White DP. Pharyngeal pressure and flow effects on genioglossus activation in normal subjects. Am J Respir Crit Care Med. 2002 Jan 1; 165(1):71-7. PMID: 11779733.
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