Assuntina Sacco

Title(s)Associate Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Interdisciplinary Approach to Expedited Outpatient Gastrostomy Tube Placement in Head and Neck Cancer Patients: A Single Center Retrospective Study. Acad Radiol. 2024 Mar 22. Haldeman PB, Ghani MA, Rubio P, Pineda M, Califano J, Sacco AG, Minocha J, Berman ZT. PMID: 38521613.
      View in: PubMed   Mentions:    Fields:    
    2. Radiotherapy Plus Cisplatin With or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial. JAMA Oncol. 2023 Nov 01; 9(11):1565-1573. Wong SJ, Torres-Saavedra PA, Saba NF, Shenouda G, Bumpous JM, Wallace RE, Chung CH, El-Naggar AK, Gwede CK, Burtness B, Tennant PA, Dunlap NE, Redman R, Stokes WA, Rudra S, Mell LK, Sacco AG, Spencer SA, Nabell L, Yao M, Cury FL, Mitchell DL, Jones CU, Firat S, Contessa JN, Galloway T, Currey A, Harris J, Curran WJ, Le QT. PMID: 37768670; PMCID: PMC10540060.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    3. Quantitative prediction of aspiration risk in head and neck cancer patients treated with radiation therapy. Oral Oncol. 2022 Nov 19; 136:106247. Liu HC, Williamson CW, Zou J, Todd JR, Nelson TJ, Hill LM, Linnemeyer KE, Henderson G, Madgula P, Faung B, Sacco AG, Vitzthum LK, Weissbrod PA, Blumenfeld LS, Mell LK. PMID: 36410204.
      View in: PubMed   Mentions: 4     Fields:    
    4. A phase I study of avelumab, palbociclib, and cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma. Oral Oncol. 2022 Dec; 135:106219. Dennis MJ, Sacco AG, Qi Y, Bykowski J, Pittman E, Chen R, Messer K, Cohen EEW, Gold KA. PMID: 36279618.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    5. Retreatment of Recurrent or Second Primary Head and Neck Cancer After Prior Radiation: Executive Summary of the American Radium Society Appropriate Use Criteria. Int J Radiat Oncol Biol Phys. 2022 07 15; 113(4):759-786. Ward MC, Koyfman SA, Bakst RL, Margalit DN, Beadle BM, Beitler JJ, Chang SS, Cooper JS, Galloway TJ, Ridge JA, Robbins JR, Sacco AG, Tsai CJ, Yom SS, Siddiqui F. PMID: 35398456.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    6. Inevitable Progress-Relying on the Immune System, Not Chance. Clin Cancer Res. 2022 02 01; 28(3):435-437. Sacco AG, Cohen EEW. PMID: 34848533.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Head and neck cancer survivorship consensus statement from the American Head and Neck Society. Laryngoscope Investig Otolaryngol. 2022 Feb; 7(1):70-92. Goyal N, Day A, Epstein J, Goodman J, Graboyes E, Jalisi S, Kiess AP, Ku JA, Miller MC, Panwar A, Patel VA, Sacco A, Sandulache V, Williams AM, Deschler D, Farwell DG, Nathan CA, Fakhry C, Agrawal N. PMID: 35155786; PMCID: PMC8823162.
      View in: PubMed   Mentions: 16  
    8. Asymptomatic detection of SARS-CoV-2 among cancer patients receiving infusional anti-cancer therapy. Cancer Med. 2021 12; 10(24):8763-8767. Shaya J, Cabal A, Nonato T, Torriani F, Califano J, Lippman S, Sacco A, McKay RR. PMID: 34708934; PMCID: PMC8646446.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    9. Evaluation of Extended-Release Oxycodone Administered through Enteral Tubes for the Management of Pain in Patients with Head and Neck Cancer: A Case Series. J Pain Palliat Care Pharmacother. 2021 Dec; 35(4):240-245. McGann M, Sacco A, Barnachea L. PMID: 34506216.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Quality improvement intervention to reduce time to postoperative radiation in head and neck free flap patients. Head Neck. 2021 11; 43(11):3530-3539. Voora RS, Stramiello JA, Sumner WA, Finegersh A, Mohammadzadeh A, Fouania J, Ramsey C, Blumenfeld L, Sacco AG, Mell LK, Califano JA, Orosco RK. PMID: 34492135.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. Pembrolizumab plus cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma: an open-label, multi-arm, non-randomised, multicentre, phase 2 trial. Lancet Oncol. 2021 06; 22(6):883-892. Sacco AG, Chen R, Worden FP, Wong DJL, Adkins D, Swiecicki P, Chai-Ho W, Oppelt P, Ghosh D, Bykowski J, Molinolo A, Pittman E, Estrada MV, Gold K, Daniels G, Lippman SM, Natsuhara A, Messer K, Cohen EEW. PMID: 33989559.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCTClinical Trials
    12. Palbociclib and cetuximab compared with placebo and cetuximab in platinum-resistant, cetuximab-naïve, human papillomavirus-unrelated recurrent or metastatic head and neck squamous cell carcinoma: A double-blind, randomized, phase 2 trial. Oral Oncol. 2021 04; 115:105192. Adkins DR, Lin JC, Sacco A, Ley J, Oppelt P, Vanchenko V, Komashko N, Yen CJ, Wise-Draper T, Lopez-Picazo Gonzalez J, Radulovic S, Shen Q, Thurm H, Martini JF, Hoffman J, Huang X, Melichar B, Tahara M. PMID: 33571736.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    13. Systematic review of postoperative therapy for resected squamous cell carcinoma of the head and neck: Executive summary of the American Radium Society appropriate use criteria. Head Neck. 2021 01; 43(1):367-391. Margalit DN, Sacco AG, Cooper JS, Ridge JA, Bakst RL, Beadle BM, Beitler JJ, Chang SS, Chen AM, Galloway TJ, Koyfman SA, Mita C, Robbins JR, Tsai CJ, Truong MT, Yom SS, Siddiqui F. PMID: 33098180; PMCID: PMC7756212.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Comparison of Hematologic Toxicity and Bone Marrow Compensatory Response in Head and Neck vs. Cervical Cancer Patients Undergoing Chemoradiotherapy. Front Oncol. 2020; 10:1179. Vitzthum LK, Heide ES, Park H, Williamson CW, Sheridan P, Huynh-Le MP, Sirak I, Wei L, Tarnawski R, Mahantshetty U, Nguyen C, Mayadev J, Yashar CM, Sacco AG, Mell LK. PMID: 32793487; PMCID: PMC7385402.
      View in: PubMed   Mentions: 5  
    15. Emergency changes in international guidelines on treatment for head and neck cancer patients during the COVID-19 pandemic. Oral Oncol. 2020 08; 107:104734. Chaves ALF, Castro AF, Marta GN, Junior GC, Ferris RL, Giglio RE, Golusinski W, Gorphe P, Hosal S, Leemans CR, Magné N, Mehanna H, Mesía R, Netto E, Psyrri A, Sacco AG, Shah J, Simon C, Vermorken JB, Kowalski LP. PMID: 32353793; PMCID: PMC7180373.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCellsPHPublic Health
    16. Evaluation of pharmacist interventions in a head and neck medical oncology clinic. J Oncol Pharm Pract. 2020 Sep; 26(6):1390-1396. Lau KM, Saunders IM, Sacco AG, Barnachea LC. PMID: 31937188.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Next generation sequencing of cell free circulating tumor DNA in blood samples of recurrent and metastatic head and neck cancer patients. Transl Cancer Res. 2020 Jan; 9(1):203-209. Porter A, Natsuhara M, Daniels GA, Patel SP, Sacco AG, Bykowski J, Banks KC, Cohen EEW. PMID: 35117174; PMCID: PMC8798156.
      View in: PubMed   Mentions: 10  
    18. Palbociclib and cetuximab in platinum-resistant and in cetuximab-resistant human papillomavirus-unrelated head and neck cancer: a multicentre, multigroup, phase 2 trial. Lancet Oncol. 2019 09; 20(9):1295-1305. Adkins D, Ley J, Neupane P, Worden F, Sacco AG, Palka K, Grilley-Olson JE, Maggiore R, Salama NN, Trinkaus K, Van Tine BA, Steuer CE, Saba NF, Oppelt P. PMID: 31351869.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCellsCTClinical Trials
    19. Adjuvant and Neoadjuvant Treatment of Skin Cancer. Facial Plast Surg Clin North Am. 2019 Feb; 27(1):139-150. Sacco AG, Daniels GA. PMID: 30420067.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Effect of Adding Motolimod to Standard Combination Chemotherapy and Cetuximab Treatment of Patients With Squamous Cell Carcinoma of the Head and Neck: The Active8 Randomized Clinical Trial. JAMA Oncol. 2018 11 01; 4(11):1583-1588. Ferris RL, Saba NF, Gitlitz BJ, Haddad R, Sukari A, Neupane P, Morris JC, Misiukiewicz K, Bauman JE, Fenton M, Jimeno A, Adkins DR, Schneider CJ, Sacco AG, Shirai K, Bowles DW, Gibson M, Nwizu T, Gottardo R, Manjarrez KL, Dietsch GN, Bryan JK, Hershberg RM, Cohen EEW. PMID: 29931076; PMCID: PMC6248084.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    21. Cost-effectiveness Analysis of Nivolumab for Treatment of Platinum-Resistant Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck. J Natl Cancer Inst. 2018 05 01; 110(5):479-485. Tringale KR, Carroll KT, Zakeri K, Sacco AG, Barnachea L, Murphy JD. PMID: 29126314; PMCID: PMC5946900.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    22. Positive Surgical Margins in the 10 Most Common Solid Cancers. Sci Rep. 2018 04 09; 8(1):5686. Orosco RK, Tapia VJ, Califano JA, Clary B, Cohen EEW, Kane C, Lippman SM, Messer K, Molinolo A, Murphy JD, Pang J, Sacco A, Tringale KR, Wallace A, Nguyen QT. PMID: 29632347; PMCID: PMC5890246.
      View in: PubMed   Mentions: 70     Fields:    Translation:Humans
    23. Chronic Opioid Use Following Surgery for Oral Cavity Cancer. JAMA Otolaryngol Head Neck Surg. 2017 12 01; 143(12):1187-1194. Pang J, Tringale KR, Tapia VJ, Moss WJ, May ME, Furnish T, Barnachea L, Brumund KT, Sacco AG, Weisman RA, Nguyen QT, Harris JP, Coffey CS, Califano JA. PMID: 28445584; PMCID: PMC5824304.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    24. Hypermutated Circulating Tumor DNA: Correlation with Response to Checkpoint Inhibitor-Based Immunotherapy. Clin Cancer Res. 2017 Oct 01; 23(19):5729-5736. Khagi Y, Goodman AM, Daniels GA, Patel SP, Sacco AG, Randall JM, Bazhenova LA, Kurzrock R. PMID: 28972084; PMCID: PMC5678984.
      View in: PubMed   Mentions: 114     Fields:    Translation:Humans
    25. Serum antibodies open the door to prediction and prognostication in human papillomavirus-related head and neck cancer. Cancer. 2017 11 15; 123(22):4310-4313. Sacco AG, Cohen EE. PMID: 28950413.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. E6 and E7 Antibody Levels Are Potential Biomarkers of Recurrence in Patients with Advanced-Stage Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma. Clin Cancer Res. 2017 Jun 01; 23(11):2723-2729. Spector ME, Sacco AG, Bellile E, Taylor JMG, Jones T, Sun K, Brown WC, Birkeland AC, Bradford CR, Wolf GT, Prince ME, Moyer JS, Malloy K, Swiecicki P, Eisbruch A, McHugh JB, Chepeha DB, Rozek L, Worden FP. PMID: 27872102; PMCID: PMC5438906.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    27. Cost-Effectiveness Analysis of Elective Neck Dissection in Patients With Clinically Node-Negative Oral Cavity Cancer. J Clin Oncol. 2016 11 10; 34(32):3886-3891. Acevedo JR, Fero KE, Wilson B, Sacco AG, Mell LK, Coffey CS, Murphy JD. PMID: 27551113; PMCID: PMC5457359.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    28. A phase II trial of the BCL-2 homolog domain 3 mimetic AT-101 in combination with docetaxel for recurrent, locally advanced, or metastatic head and neck cancer. Invest New Drugs. 2016 08; 34(4):481-9. Swiecicki PL, Bellile E, Sacco AG, Pearson AT, Taylor JM, Jackson TL, Chepeha DB, Spector ME, Shuman A, Malloy K, Moyer J, McKean E, McLean S, Sukari A, Wolf GT, Eisbruch A, Prince M, Bradford C, Carey TE, Wang S, Nör JE, Worden FP. PMID: 27225873; PMCID: PMC5036856.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    29. Molecularly targeted therapy for the treatment of head and neck cancer: a review of the ErbB family inhibitors. Onco Targets Ther. 2016; 9:1927-43. Sacco AG, Worden FP. PMID: 27110122; PMCID: PMC4831599.
      View in: PubMed   Mentions: 33  
    30. A phase II study evaluating axitinib in patients with unresectable, recurrent or metastatic head and neck cancer. Invest New Drugs. 2015 Dec; 33(6):1248-56. Swiecicki PL, Zhao L, Belile E, Sacco AG, Chepeha DB, Dobrosotskaya I, Spector M, Shuman A, Malloy K, Moyer J, McKean E, McLean S, Wolf GT, Eisbruch A, Prince M, Bradford C, Carey T, Worden FP. PMID: 26453566.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    31. Association Between Multimodality Neck Treatment and Work and Leisure Impairment: A Disease-Specific Measure to Assess Both Impairment and Rehabilitation After Neck Dissection. JAMA Otolaryngol Head Neck Surg. 2015 Oct; 141(10):888-93. Gallagher KK, Sacco AG, Lee JS, Taylor R, Chanowski EJ, Bradford CR, Prince ME, Moyer JS, Wolf GT, Worden FP, Eisbruch A, Chepeha DB. PMID: 26426565.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    32. Current Treatment Options for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma. J Clin Oncol. 2015 Oct 10; 33(29):3305-13. Sacco AG, Cohen EE. PMID: 26351341.
      View in: PubMed   Mentions: 156     Fields:    Translation:Humans
    33. Prevalence and predictive role of p16 and epidermal growth factor receptor in surgically treated oropharyngeal and oral cavity cancer. Head Neck. 2013 Aug; 35(8):1083-90. Chandarana SP, Lee JS, Chanowski EJ, Sacco AG, Bradford CR, Wolf GT, Prince ME, Moyer JS, Eisbruch A, Worden FP, Giordano TJ, Kumar B, Cordell KG, Carey TE, Chepeha DB. PMID: 22907805; PMCID: PMC4118462.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    34. Revascularized tissue transplant and internal transport disk distraction osteogenesis for the reconstruction of complex composite mandibular defects. J Otolaryngol Head Neck Surg. 2011 Aug; 40(4):330-6. Chanowski EJ, Sacco AG, Fung K, Prince ME, Moyer JS, Chepeha DB. PMID: 21777552.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Thoracodorsal artery scapular tip autogenous transplant: vascularized bone with a long pedicle and flexible soft tissue. Arch Otolaryngol Head Neck Surg. 2010 Oct; 136(10):958-64. Chepeha DB, Khariwala SS, Chanowski EJ, Zumsteg JW, Malloy KM, Moyer JS, Prince ME, Sacco AG, Lee JS. PMID: 20956740.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    36. Oropharyngoplasty with template-based reconstruction of oropharynx defects. Arch Otolaryngol Head Neck Surg. 2009 Sep; 135(9):887-94. Chepeha DB, Sacco AG, Erickson VR, Lyden T, Haxer M, Moyer J, Teknos TN, Prince ME, Eisbruch A, Bradford CR, Wolf GT. PMID: 19770421.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Advanced squamous cell carcinoma of the oropharynx: efficacy of positron emission tomography and computed tomography for determining primary tumor response during induction chemotherapy. Head Neck. 2009 Apr; 31(4):452-60. Chepeha DB, Sacco AG, Oxford LE, Karamchandani R, Miller TH, Teknos TN, Bradford CR, Eisbruch A, Worden FM, Urba SG, Mukherji SK, Bui C, Frey KA, Wolf GT, Lee JS. PMID: 19189338.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    38. Rectangle tongue template for reconstruction of the hemiglossectomy defect. Arch Otolaryngol Head Neck Surg. 2008 Sep; 134(9):993-8. Chepeha DB, Teknos TN, Shargorodsky J, Sacco AG, Lyden T, Prince ME, Bradford CR, Wolf GT. PMID: 18794446.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    39. Lateral oromandibular defect: when is it appropriate to use a bridging reconstruction plate combined with a soft tissue revascularized flap? Head Neck. 2008 Jun; 30(6):709-17. Chepeha DB, Teknos TN, Fung K, Shargorodsky J, Sacco AG, Nussenbaum B, Jones L, Eisbruch A, Bradford CR, Prince ME, Moyer JS, Lee JS, Wolf GT. PMID: 18286487.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    40. Current status of transport-disc-distraction osteogenesis for mandibular reconstruction. Lancet Oncol. 2007 Apr; 8(4):323-30. Sacco AG, Chepeha DB. PMID: 17395106.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    41. Mapping of epitopes on porcine zona pellucida-3 alpha by monoclonal antibodies inhibiting oocyte-sperm interaction. Biol Reprod. 1996 Aug; 55(2):410-5. Gupta SK, Chadha K, Harris JD, Yurewicz EC, Sacco AG, Kolluri SK, Afzalpurka A. PMID: 8828847.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    42. Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: the ZPA, ZPB and ZPC gene families. DNA Seq. 1994; 4(6):361-93. Harris JD, Hibler DW, Fontenot GK, Hsu KT, Yurewicz EC, Sacco AG. PMID: 7841460.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    43. Nucleotide sequence of cDNA encoding ZP3 alpha, a sperm-binding glycoprotein from zona pellucida of pig oocyte. Biochim Biophys Acta. 1993 Aug 19; 1174(2):211-4. Yurewicz EC, Hibler D, Fontenot GK, Sacco AG, Harris J. PMID: 8357839.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
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