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    Amy Jak

    TitleAssociate Professor In Residence
    SchoolUniversity of California, San Diego
    DepartmentPsychiatry
    Address9500 Gilman Drive #9116B
    CA La Jolla 92093
    Phone858-642-3742
    vCardDownload vCard

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      Biography

      Dr. Jak received her doctorate in Clinical Psychology, with specialization in neuropsychology, from the University of Cincinnati (2004). She completed a postdoctoral fellowship in neuropsychology at the VA San Diego Healthcare System/Veteran’s Medical Research Foundation from 2004-2007. Currently, she is an Assistant Professor (In Residence) of Psychiatry at UCSD and a Staff Neurosychologist and Director, TBI Cognitive Rehabilitation Clinic, at the Veterans Affairs San Diego Healthcare System. Dr. Jak’s research interests are in novel treatments for mild TBI as well as in cognitive aging and mild cognitive impairment.

      Research Interests

      Dr. Jak’s research focuses on neuropsychology and neuroimaging in normal aging and mild cognitive impairment. Specifically, her current research examines how protective behavioral factors (e.g., physically and mentally active lifestyles) impact cognition and brain structural integrity. Additionally, her research examines the potential for activity levels to modify genetic risk for cognitive decline. Other research interests center on the neuropsychological presentation of mild cognitive impairment, mild traumatic brain injury, and post-traumatic stress disorder.

      Clinical Focus

      Dr. Jak is the Director of Traumatic Brain Injury Cognitive Rehabilitation at the VA San Diego Healthcare system and provides psychoeducation and training in compensatory strategies to veterans with mild to moderate TBI. She is also a Clinical Neuropsychologist within the Department's private practice plan (UCSD Neuropsychological Associates). She conducts clinical neuropsychological evaluations of adults with a wide range of neurologic and psychiatric disorders, with particular emphasis on dementia and traumatic brain injury.


      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Jurick SM, Weissberger GH, Clark LR, Wierenga CE, Chang YL, Schiehser DM, Han SD, Jak A, Dev SI, Bondi MW. Faulty Adaptation to Repeated Face-Name Associative Pairs in Mild Cognitive Impairment is Predictive of Cognitive Decline. Arch Clin Neuropsychol. 2017 Jun 26; 1-16. PMID: 28655152.
        View in: PubMed
      2. Jurick SM, Crocker LD, Sanderson-Cimino M, Keller AV, Trenova LS, Boyd BL, Twamley EW, Rodgers CS, Schiehser DM, Aupperle RL, Jak A. Contributions to Executive Dysfunction in Operation Enduring Freedom/Operation Iraqi Freedom Veterans With Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury. J Head Trauma Rehabil. 2017 May 17. PMID: 28520663.
        View in: PubMed
      3. Storzbach D, Twamley EW, Roost MS, Golshan S, Williams RM, O'Neil M, Jak A, Turner AP, Kowalski HM, Pagulayan KF, Huckans M. Compensatory Cognitive Training for Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn Veterans With Mild Traumatic Brain Injury. J Head Trauma Rehabil. 2017 Jan/Feb; 32(1):16-24. PMID: 27022961.
        View in: PubMed
      4. Jak A, Crocker LD, Aupperle RL, Clausen A, Bomyea J. Neurocognition in PTSD: Treatment Insights and Implications. Curr Top Behav Neurosci. 2016 Dec 27. PMID: 28025811.
        View in: PubMed
      5. Clark AL, Sorg SF, Schiehser DM, Bigler ED, Bondi MW, Jacobson MW, Jak A, Delano-Wood L. White Matter Associations With Performance Validity Testing in Veterans With Mild Traumatic Brain Injury: The Utility of Biomarkers in Complicated Assessment. J Head Trauma Rehabil. 2016 Sep-Oct; 31(5):346-59. PMID: 26360002; PMCID: PMC4786475 [Available on 09/01/17].
        View in: PubMed, PubMed Central
      6. Schiehser DM, Delano-Wood L, Jak A, Hanson KL, Sorg SF, Orff H, Clark AL. Predictors of cognitive and physical fatigue in post-acute mild-moderate traumatic brain injury. Neuropsychol Rehabil. 2017 Oct; 27(7):1031-1046. PMID: 27535726.
        View in: PubMed
      7. Hanson KL, Schiehser DM, Clark AL, Sorg SF, Kim RT, Jacobson MW, Werhane ML, Jak A, Twamley EW, Delano-Wood L. Problem alcohol use in veterans with mild traumatic brain injury: Associations with cognitive performance and psychiatric symptoms. J Clin Exp Neuropsychol. 2016 Dec; 38(10):1115-30. PMID: 27430280.
        View in: PubMed
      8. Jak A, Preis SR, Beiser AS, Seshadri S, Wolf PA, Bondi MW, Au R. Neuropsychological Criteria for Mild Cognitive Impairment and Dementia Risk in the Framingham Heart Study. J Int Neuropsychol Soc. 2016 Oct; 22(9):937-943. PMID: 27029348.
        View in: PubMed
      9. Edmonds EC, Delano-Wood L, Jak A, Galasko DR, Salmon DP, Bondi MW. "Missed" Mild Cognitive Impairment: High False-Negative Error Rate Based on Conventional Diagnostic Criteria. J Alzheimers Dis. 2016 03 31; 52(2):685-91. PMID: 27031477; PMCID: PMC4879874.
        View in: PubMed, PubMed Central
      10. Bomyea J, Lang AJ, Delano-Wood L, Jak A, Hanson KL, Sorg S, Clark AL, Schiehser DM. Neuropsychiatric Predictors of Post-Injury Headache After Mild-Moderate Traumatic Brain Injury in Veterans. Headache. 2016 Apr; 56(4):699-710. PMID: 27028095.
        View in: PubMed
      11. Vuoksimaa E, Panizzon MS, Chen CH, Fiecas M, Eyler LT, Fennema-Notestine C, Hagler DJ, Franz CE, Jak A, Lyons MJ, Neale MC, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. Is bigger always better? The importance of cortical configuration with respect to cognitive ability. Neuroimage. 2016 Apr 01; 129:356-366. PMID: 26827810; PMCID: PMC4838639 [Available on 04/01/17].
        View in: PubMed, PubMed Central
      12. Jurick SM, Bangen KJ, Evangelista ND, Sanderson-Cimino M, Delano-Wood L, Jak A. Advanced neuroimaging to quantify myelin in vivo: Application to mild TBI. Brain Inj. 2016; 30(12):1452-1457. PMID: 27834545.
        View in: PubMed
      13. Jurick SM, Twamley EW, Crocker LD, Hays CC, Orff HJ, Golshan S, Jak A. Postconcussive symptom overreporting in Iraq/Afghanistan Veterans with mild traumatic brain injury. J Rehabil Res Dev. 2016; 53(5):571-584. PMID: 27898153.
        View in: PubMed
      14. Leung A, Shukla S, Fallah A, Song D, Lin L, Golshan S, Tsai A, Jak A, Polston G, Lee R. Repetitive Transcranial Magnetic Stimulation in Managing Mild Traumatic Brain Injury-Related Headaches. Neuromodulation. 2016 Feb; 19(2):133-41. PMID: 26555886.
        View in: PubMed
      15. Twamley EW, Thomas KR, Gregory AM, Jak A, Bondi MW, Delis DC, Lohr JB. CogSMART Compensatory Cognitive Training for Traumatic Brain Injury: Effects Over 1 Year. J Head Trauma Rehabil. 2015 Nov-Dec; 30(6):391-401. PMID: 25033034.
        View in: PubMed
      16. Jak A, Aupperle R, Rodgers CS, Lang AJ, Schiehser DM, Norman SB, Twamley EW. Evaluation of a hybrid treatment for Veterans with comorbid traumatic brain injury and posttraumatic stress disorder: Study protocol for a randomized controlled trial. Contemp Clin Trials. 2015 Nov; 45(Pt B):210-216. PMID: 26500169.
        View in: PubMed
      17. Ahmed S, Brennan L, Eppig J, Price CC, Lamar M, Delano-Wood L, Bangen KJ, Edmonds EC, Clark L, Nation DA, Jak A, Au R, Swenson R, Bondi MW, Libon DJ. Visuoconstructional Impairment in Subtypes of Mild Cognitive Impairment. Appl Neuropsychol Adult. 2016; 23(1):43-52. PMID: 26397732.
        View in: PubMed
      18. Walter KH, Jak A, Twamley EW. Psychiatric comorbidity effects on compensatory cognitive training outcomes for veterans with traumatic brain injuries. Rehabil Psychol. 2015 Aug; 60(3):303-8. PMID: 26147236.
        View in: PubMed
      19. Schiehser DM, Twamley EW, Liu L, Matevosyan A, Filoteo JV, Jak A, Orff HJ, Hanson KL, Sorg SF, Delano-Wood L. The Relationship Between Postconcussive Symptoms and Quality of Life in Veterans With Mild to Moderate Traumatic Brain Injury. J Head Trauma Rehabil. 2015 Jul-Aug; 30(4):E21-8. PMID: 24922041.
        View in: PubMed
      20. Jak A, Gregory A, Orff HJ, Colón C, Steele N, Schiehser DM, Delano-Wood L, Jurick SM, Twamley EW. Neuropsychological performance in treatment-seeking Operation Enduring Freedom/Operation Iraqi Freedom Veterans with a history of mild traumatic brain injury. J Clin Exp Neuropsychol. 2015; 37(4):379-88. PMID: 25850338.
        View in: PubMed
      21. Schiehser DM, Delano-Wood L, Jak A, Matthews SC, Simmons AN, Jacobson MW, Filoteo JV, Bondi MW, Orff HJ, Liu L. Validation of the Modified Fatigue Impact Scale in mild to moderate traumatic brain injury. J Head Trauma Rehabil. 2015 Mar-Apr; 30(2):116-21. PMID: 24413076.
        View in: PubMed
      22. Docherty AR, Hagler DJ, Panizzon MS, Neale MC, Eyler LT, Fennema-Notestine C, Franz CE, Jak A, Lyons MJ, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. Does degree of gyrification underlie the phenotypic and genetic associations between cortical surface area and cognitive ability? Neuroimage. 2015 Feb 01; 106:154-60. PMID: 25433211; PMCID: PMC4313767.
        View in: PubMed, PubMed Central
      23. Jak A, Panizzon MS, Spoon KM, Fennema-Notestine C, Franz CE, Thompson WK, Jacobson KC, Xian H, Eyler LT, Vuoksimaa E, Toomey R, Lyons MJ, Neale MC, Tsuang MT, Dale AM, Kremen WS. Hippocampal atrophy varies by neuropsychologically defined MCI among men in their 50s. Am J Geriatr Psychiatry. 2015 May; 23(5):456-65. PMID: 25306196; PMCID: PMC4345132.
        View in: PubMed, PubMed Central
      24. Edmonds EC, Delano-Wood L, Clark LR, Jak A, Nation DA, McDonald CR, Libon DJ, Au R, Galasko D, Salmon DP, Bondi MW. Susceptibility of the conventional criteria for mild cognitive impairment to false-positive diagnostic errors. Alzheimers Dement. 2015 Apr; 11(4):415-24. PMID: 24857234; PMCID: PMC4241187.
        View in: PubMed, PubMed Central
      25. Kremen WS, Jak A, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC, Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. Authors' response to: commentary by Johnson et al. Int J Epidemiol. 2014 Apr; 43(2):612-3. PMID: 24760875; PMCID: PMC3997381.
        View in: PubMed, PubMed Central
      26. Vuoksimaa E, Panizzon MS, Chen CH, Fiecas M, Eyler LT, Fennema-Notestine C, Hagler DJ, Fischl B, Franz CE, Jak A, Lyons MJ, Neale MC, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. The Genetic Association Between Neocortical Volume and General Cognitive Ability Is Driven by Global Surface Area Rather Than Thickness. Cereb Cortex. 2015 Aug; 25(8):2127-37. PMID: 24554725; PMCID: PMC4494025.
        View in: PubMed, PubMed Central
      27. Bondi MW, Edmonds EC, Jak A, Clark LR, Delano-Wood L, McDonald CR, Nation DA, Libon DJ, Au R, Galasko D, Salmon DP. Neuropsychological criteria for mild cognitive impairment improves diagnostic precision, biomarker associations, and progression rates. J Alzheimers Dis. 2014; 42(1):275-89. PMID: 24844687; PMCID: PMC4133291.
        View in: PubMed, PubMed Central
      28. Zlatar ZZ, Wierenga CE, Bangen KJ, Liu TT, Jak A. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. J Alzheimers Dis. 2014; 41(3):809-17. PMID: 24685629; PMCID: PMC4259215.
        View in: PubMed, PubMed Central
      29. Twamley EW, Jak A, Delis DC, Bondi MW, Lohr JB. Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) for veterans with traumatic brain injury: pilot randomized controlled trial. J Rehabil Res Dev. 2014; 51(1):59-70. PMID: 24805894.
        View in: PubMed
      30. Sorg SF, Delano-Wood L, Luc N, Schiehser DM, Hanson KL, Nation DA, Lanni E, Jak A, Lu K, Meloy MJ, Frank LR, Lohr JB, Bondi MW. White matter integrity in veterans with mild traumatic brain injury: associations with executive function and loss of consciousness. J Head Trauma Rehabil. 2014 Jan-Feb; 29(1):21-32. PMID: 23640539; PMCID: PMC4300196.
        View in: PubMed, PubMed Central
      31. Kremen WS, Jak A, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC, Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. Early identification and heritability of mild cognitive impairment. Int J Epidemiol. 2014 Apr; 43(2):600-10. PMID: 24370560; PMCID: PMC3997374.
        View in: PubMed, PubMed Central
      32. Eyler LT, Vuoksimaa E, Panizzon MS, Fennema-Notestine C, Neale MC, Chen CH, Jak A, Franz CE, Lyons MJ, Thompson WK, Spoon KM, Fischl B, Dale AM, Kremen WS. Conceptual and data-based investigation of genetic influences and brain asymmetry: a twin study of multiple structural phenotypes. J Cogn Neurosci. 2014 May; 26(5):1100-17. PMID: 24283492; PMCID: PMC3999438.
        View in: PubMed, PubMed Central
      33. Clark LR, Delano-Wood L, Libon DJ, McDonald CR, Nation DA, Bangen KJ, Jak A, Au R, Salmon DP, Bondi MW. Are empirically-derived subtypes of mild cognitive impairment consistent with conventional subtypes? J Int Neuropsychol Soc. 2013 Jul; 19(6):635-45. PMID: 23552486; PMCID: PMC3742806.
        View in: PubMed, PubMed Central
      34. Vuoksimaa E, Panizzon MS, Chen CH, Eyler LT, Fennema-Notestine C, Fiecas MJ, Fischl B, Franz CE, Grant MD, Jak A, Lyons MJ, Neale MC, Thompson WK, Tsuang MT, Xian H, Dale AM, Kremen WS. Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age. Neuropsychologia. 2013 May; 51(6):1124-31. PMID: 23499725; PMCID: PMC3660613.
        View in: PubMed, PubMed Central
      35. Huckans M, Hutson L, Twamley E, Jak A, Kaye J, Storzbach D. Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults: working toward a theoretical model and evidence-based interventions. Neuropsychol Rev. 2013 Mar; 23(1):63-80. PMID: 23471631; PMCID: PMC3640648.
        View in: PubMed, PubMed Central
      36. Jak A, Seelye AM, Jurick SM. Crosswords to computers: a critical review of popular approaches to cognitive enhancement. Neuropsychol Rev. 2013 Mar; 23(1):13-26. PMID: 23423553.
        View in: PubMed
      37. Nation DA, Wierenga CE, Clark LR, Dev SI, Stricker NH, Jak A, Salmon DP, Delano-Wood L, Bangen KJ, Rissman RA, Liu TT, Bondi MW. Cortical and subcortical cerebrovascular resistance index in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis. 2013; 36(4):689-98. PMID: 23666173; PMCID: PMC4089500.
        View in: PubMed, PubMed Central
      38. Eyler LT, Chen CH, Panizzon MS, Fennema-Notestine C, Neale MC, Jak A, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Grant M, Prom-Wormley E, Seidman LJ, Tsuang MT, Fiecas MJ, Dale AM, Kremen WS. A comparison of heritability maps of cortical surface area and thickness and the influence of adjustment for whole brain measures: a magnetic resonance imaging twin study. Twin Res Hum Genet. 2012 Jun; 15(3):304-14. PMID: 22856366; PMCID: PMC3549553.
        View in: PubMed, PubMed Central
      39. Kubarych TS, Prom-Wormley EC, Franz CE, Panizzon MS, Dale AM, Fischl B, Eyler LT, Fennema-Notestine C, Grant MD, Hauger RL, Hellhammer DH, Jak A, Jernigan TL, Lupien SJ, Lyons MJ, Mendoza SP, Neale MC, Seidman LJ, Tsuang MT, Kremen WS. A multivariate twin study of hippocampal volume, self-esteem and well-being in middle-aged men. Genes Brain Behav. 2012 Jul; 11(5):539-44. PMID: 22471516; PMCID: PMC3389179.
        View in: PubMed, PubMed Central
      40. Wierenga CE, Dev SI, Shin DD, Clark LR, Bangen KJ, Jak A, Rissman RA, Liu TT, Salmon DP, Bondi MW. Effect of mild cognitive impairment and APOE genotype on resting cerebral blood flow and its association with cognition. J Cereb Blood Flow Metab. 2012 Aug; 32(8):1589-99. PMID: 22549621; PMCID: PMC3421098.
        View in: PubMed, PubMed Central
      41. Chen CH, Gutierrez ED, Thompson W, Panizzon MS, Jernigan TL, Eyler LT, Fennema-Notestine C, Jak A, Neale MC, Franz CE, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AM. Hierarchical genetic organization of human cortical surface area. Science. 2012 Mar 30; 335(6076):1634-6. PMID: 22461613; PMCID: PMC3690329.
        View in: PubMed, PubMed Central
      42. Panizzon MS, Fennema-Notestine C, Kubarych TS, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Hamza S, Jak A, Jernigan TL, Lyons MJ, Neale MC, Prom-Wormley EC, Seidman L, Tsuang MT, Wu H, Xian H, Dale AM, Kremen WS. Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics? Neuroimage. 2012 Apr 15; 60(3):1686-95. PMID: 22500923; PMCID: PMC3328105.
        View in: PubMed, PubMed Central
      43. Nation DA, Delano-Wood L, Bangen KJ, Wierenga CE, Jak A, Hansen LA, Galasko DR, Salmon DP, Bondi MW. Antemortem pulse pressure elevation predicts cerebrovascular disease in autopsy-confirmed Alzheimer's disease. J Alzheimers Dis. 2012; 30(3):595-603. PMID: 22451309; PMCID: PMC3370943.
        View in: PubMed, PubMed Central
      44. Delano-Wood L, Stricker NH, Sorg SF, Nation DA, Jak A, Woods SP, Libon DJ, Delis DC, Frank LR, Bondi MW. Posterior cingulum white matter disruption and its associations with verbal memory and stroke risk in mild cognitive impairment. J Alzheimers Dis. 2012; 29(3):589-603. PMID: 22466061; PMCID: PMC3341099.
        View in: PubMed, PubMed Central
      45. Bangen KJ, Restom K, Liu TT, Wierenga CE, Jak A, Salmon DP, Bondi MW. Assessment of Alzheimer's disease risk with functional magnetic resonance imaging: an arterial spin labeling study. J Alzheimers Dis. 2012; 31 Suppl 3:S59-74. PMID: 22531427; PMCID: PMC3443702.
        View in: PubMed, PubMed Central
      46. Jak A. The impact of physical and mental activity on cognitive aging. Curr Top Behav Neurosci. 2012; 10:273-91. PMID: 21818703.
        View in: PubMed
      47. Chen CH, Panizzon MS, Eyler LT, Jernigan TL, Thompson W, Fennema-Notestine C, Jak A, Neale MC, Franz CE, Hamza S, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AM. Genetic influences on cortical regionalization in the human brain. Neuron. 2011 Nov 17; 72(4):537-44. PMID: 22099457; PMCID: PMC3222857.
        View in: PubMed, PubMed Central
      48. Panizzon MS, Hauger RL, Eaves LJ, Chen CH, Dale AM, Eyler LT, Fischl B, Fennema-Notestine C, Franz CE, Grant MD, Jacobson KC, Jak A, Lyons MJ, Mendoza SP, Neale MC, Prom-Wormley E, Seidman LJ, Tsuang MT, Xian H, Kremen WS. Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men. Neuroimage. 2012 Jan 16; 59(2):1123-31. PMID: 21983185; PMCID: PMC3230702.
        View in: PubMed, PubMed Central
      49. Schiehser DM, Delis DC, Filoteo JV, Delano-Wood L, Han SD, Jak A, Drake AI, Bondi MW. Are self-reported symptoms of executive dysfunction associated with objective executive function performance following mild to moderate traumatic brain injury? J Clin Exp Neuropsychol. 2011 Jul; 33(6):704-14. PMID: 21958432; PMCID: PMC3325052.
        View in: PubMed, PubMed Central
      50. Nation DA, Hong S, Jak A, Delano-Wood L, Mills PJ, Bondi MW, Dimsdale JE. Stress, exercise, and Alzheimer's disease: a neurovascular pathway. Med Hypotheses. 2011 Jun; 76(6):847-54. PMID: 21398043; PMCID: PMC3094492.
        View in: PubMed, PubMed Central
      51. Eyler LT, Prom-Wormley E, Panizzon MS, Kaup AR, Fennema-Notestine C, Neale MC, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Grant M, Stevens A, Pacheco J, Perry ME, Schmitt JE, Seidman LJ, Thermenos HW, Tsuang MT, Chen CH, Thompson WK, Jak A, Dale AM, Kremen WS. Genetic and environmental contributions to regional cortical surface area in humans: a magnetic resonance imaging twin study. Cereb Cortex. 2011 Oct; 21(10):2313-21. PMID: 21378112; PMCID: PMC3169660.
        View in: PubMed, PubMed Central
      52. Fennema-Notestine C, Panizzon MS, Thompson WR, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Jak A, Jernigan TL, Lyons MJ, Neale MC, Seidman LJ, Tsuang MT, Xian H, Dale AM, Kremen WS. Presence of ApoE e4 allele associated with thinner frontal cortex in middle age. J Alzheimers Dis. 2011; 26 Suppl 3:49-60. PMID: 21971450; PMCID: PMC3302177.
        View in: PubMed, PubMed Central
      53. Wierenga CE, Stricker NH, McCauley A, Simmons A, Jak A, Chang YL, Nation DA, Bangen KJ, Salmon DP, Bondi MW. Altered brain response for semantic knowledge in Alzheimer's disease. Neuropsychologia. 2011 Feb; 49(3):392-404. PMID: 21163275; PMCID: PMC3058793.
        View in: PubMed, PubMed Central
      54. Panizzon MS, Hauger R, Dale AM, Eaves LJ, Eyler LT, Fischl B, Fennema-Notestine C, Franz CE, Grant MD, Jak A, Jacobson KC, Lyons MJ, Mendoza SP, Neale MC, Prom-Wormley EC, Seidman LJ, Tsuang MT, Xian H, Kremen WS. Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men. Neurology. 2010 Sep 07; 75(10):874-80. PMID: 20819998; PMCID: PMC2938973.
        View in: PubMed, PubMed Central
      55. Nation DA, Wierenga CE, Delano-Wood L, Jak A, Delis DC, Salmon DP, Bondi MW. Elevated pulse pressure is associated with age-related decline in language ability. J Int Neuropsychol Soc. 2010 Sep; 16(5):933-8. PMID: 20663268; PMCID: PMC3008594.
        View in: PubMed, PubMed Central
      56. Han SD, Suzuki H, Jak A, Chang YL, Salmon DP, Bondi MW. Hierarchical cognitive and psychosocial predictors of amnestic mild cognitive impairment. J Int Neuropsychol Soc. 2010 Jul; 16(4):721-9. PMID: 20561399; PMCID: PMC3005198.
        View in: PubMed, PubMed Central
      57. Bangen KJ, Jak A, Schiehser DM, Delano-Wood L, Tuminello E, Han SD, Delis DC, Bondi MW. Complex activities of daily living vary by mild cognitive impairment subtype. J Int Neuropsychol Soc. 2010 Jul; 16(4):630-9. PMID: 20374675; PMCID: PMC2891154.
        View in: PubMed, PubMed Central
      58. Kremen WS, Panizzon MS, Neale MC, Fennema-Notestine C, Prom-Wormley E, Eyler LT, Stevens A, Franz CE, Lyons MJ, Grant MD, Jak A, Jernigan TL, Xian H, Fischl B, Thermenos HW, Seidman LJ, Tsuang MT, Dale AM. Heritability of brain ventricle volume: converging evidence from inconsistent results. Neurobiol Aging. 2012 Jan; 33(1):1-8. PMID: 20363053; PMCID: PMC3221930.
        View in: PubMed, PubMed Central
      59. Wierenga CE, Stricker NH, McCauley A, Simmons A, Jak A, Chang YL, Delano-Wood L, Bangen KJ, Salmon DP, Bondi MW. Increased functional brain response during word retrieval in cognitively intact older adults at genetic risk for Alzheimer's disease. Neuroimage. 2010 Jul 01; 51(3):1222-33. PMID: 20298792; PMCID: PMC2862794.
        View in: PubMed, PubMed Central
      60. Kremen WS, O'Brien RC, Panizzon MS, Prom-Wormley E, Eaves LJ, Eisen SA, Eyler LT, Hauger RL, Fennema-Notestine C, Fischl B, Grant MD, Hellhammer DH, Jak A, Jacobson KC, Jernigan TL, Lupien SJ, Lyons MJ, Mendoza SP, Neale MC, Seidman LJ, Thermenos HW, Tsuang MT, Dale AM, Franz CE. Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study. Neuroimage. 2010 Nov 15; 53(3):1093-102. PMID: 20156572; PMCID: PMC4034538.
        View in: PubMed, PubMed Central
      61. Delano-Wood L, Bondi MW, Sacco J, Abeles N, Jak A, Libon DJ, Bozoki A. Heterogeneity in mild cognitive impairment: differences in neuropsychological profile and associated white matter lesion pathology. J Int Neuropsychol Soc. 2009 Nov; 15(6):906-14. PMID: 19891820; PMCID: PMC3034688.
        View in: PubMed, PubMed Central
      62. Jak A, Urban S, McCauley A, Bangen KJ, Delano-Wood L, Corey-Bloom J, Bondi MW. Profile of hippocampal volumes and stroke risk varies by neuropsychological definition of mild cognitive impairment. J Int Neuropsychol Soc. 2009 Nov; 15(6):890-7. PMID: 19570306; PMCID: PMC2864786.
        View in: PubMed, PubMed Central
      63. Jak A, Bondi MW, Delano-Wood L, Wierenga C, Corey-Bloom J, Salmon DP, Delis DC. Quantification of five neuropsychological approaches to defining mild cognitive impairment. Am J Geriatr Psychiatry. 2009 May; 17(5):368-75. PMID: 19390294; PMCID: PMC2743175.
        View in: PubMed, PubMed Central
      64. Jak A, Bangen KJ, Wierenga CE, Delano-Wood L, Corey-Bloom J, Bondi MW. Contributions of neuropsychology and neuroimaging to understanding clinical subtypes of mild cognitive impairment. Int Rev Neurobiol. 2009; 84:81-103. PMID: 19501714; PMCID: PMC2864107.
        View in: PubMed, PubMed Central
      65. Han SD, Suzuki H, Drake AI, Jak A, Houston WS, Bondi MW. Clinical, cognitive, and genetic predictors of change in job status following traumatic brain injury in a military population. J Head Trauma Rehabil. 2009 Jan-Feb; 24(1):57-64. PMID: 19158597; PMCID: PMC3319716.
        View in: PubMed, PubMed Central
      66. Delano-Wood L, Bondi MW, Jak A, Horne NR, Schweinsburg BC, Frank LR, Wierenga CE, Delis DC, Theilmann RJ, Salmon DP. Stroke risk modifies regional white matter differences in mild cognitive impairment. Neurobiol Aging. 2010 Oct; 31(10):1721-31. PMID: 19004528; PMCID: PMC2946939.
        View in: PubMed, PubMed Central
      67. Fine EM, Delis DC, Wetter SR, Jacobson MW, Jak A, McDonald CR, Braga JC, Thal LJ, Salmon DP, Bondi MW. Cognitive discrepancies versus APOE genotype as predictors of cognitive decline in normal-functioning elderly individuals: a longitudinal study. Am J Geriatr Psychiatry. 2008 May; 16(5):366-74. PMID: 18448849; PMCID: PMC3050584.
        View in: PubMed, PubMed Central
      68. Bondi MW, Jak A, Delano-Wood L, Jacobson MW, Delis DC, Salmon DP. Neuropsychological contributions to the early identification of Alzheimer's disease. Neuropsychol Rev. 2008 Mar; 18(1):73-90. PMID: 18347989; PMCID: PMC2882236.
        View in: PubMed, PubMed Central
      69. Bangen KJ, Restom K, Liu TT, Jak A, Wierenga CE, Salmon DP, Bondi MW. Differential age effects on cerebral blood flow and BOLD response to encoding: associations with cognition and stroke risk. Neurobiol Aging. 2009 Aug; 30(8):1276-87. PMID: 18160181; PMCID: PMC2804245.
        View in: PubMed, PubMed Central
      70. Jak A, Houston WS, Nagel BJ, Corey-Bloom J, Bondi MW. Differential cross-sectional and longitudinal impact of APOE genotype on hippocampal volumes in nondemented older adults. Dement Geriatr Cogn Disord. 2007; 23(6):382-9. PMID: 17389798; PMCID: PMC2084479.
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      71. Han SD, Drake AI, Cessante LM, Jak A, Houston WS, Delis DC, Filoteo JV, Bondi MW. Apolipoprotein E and traumatic brain injury in a military population: evidence of a neuropsychological compensatory mechanism? J Neurol Neurosurg Psychiatry. 2007 Oct; 78(10):1103-8. PMID: 17287237; PMCID: PMC2117544.
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      72. Han SD, Houston WS, Jak A, Eyler LT, Nagel BJ, Fleisher AS, Brown GG, Corey-Bloom J, Salmon DP, Thal LJ, Bondi MW. Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response. Neurobiol Aging. 2007 Feb; 28(2):238-47. PMID: 16434125; PMCID: PMC1705815.
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      73. Fleck DE, Shear PK, Zimmerman ME, Getz GE, Corey KB, Jak A, Lebowitz BK, Strakowski SM. Verbal memory in mania: effects of clinical state and task requirements. Bipolar Disord. 2003 Oct; 5(5):375-80. PMID: 14525560.
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      74. Meiron L, Jak A, Shoshana C, Maria Z, Aron Z. Intrapartum maternal fever and neonatal outcome. Pediatrics. 2001 Sep; 108(3):818. PMID: 11548758.
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      75. Cohen JA, Cutter GR, Fischer JS, Goodman AD, Heidenreich FR, Jak A, Kniker JE, Kooijmans MF, Lull JM, Sandrock AW, Simon JH, Simonian NA, Whitaker JN. Use of the multiple sclerosis functional composite as an outcome measure in a phase 3 clinical trial. Arch Neurol. 2001 Jun; 58(6):961-7. PMID: 11405811.
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      76. Cohen JA, Fischer JS, Bolibrush DM, Jak A, Kniker JE, Mertz LA, Skaramagas TT, Cutter GR. Intrarater and interrater reliability of the MS functional composite outcome measure. Neurology. 2000 Feb 22; 54(4):802-6. PMID: 10690966.
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