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    Karen Arden

    TitleAdjunct Professor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0660
    CA La Jolla 92093
    Phone858-534-7812
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl GM, Bafna V, Mischel PS. Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. Nature. 2017 Feb 08. PMID: 28178237.
        View in: PubMed
      2. Dejean AS, Beisner DR, Ch'en IL, Kerdiles YM, Babour A, Arden K, Castrillon DH, DePinho RA, Hedrick SM. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nat Immunol. 2009 May; 10(5):504-13. PMID: 19363483.
        View in: PubMed
      3. Kim JJ, Li P, Huntley J, Chang JP, Arden K, Olefsky JM. FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue. Diabetes. 2009 Jun; 58(6):1275-82. PMID: 19289458.
        View in: PubMed
      4. Dengler HS, Baracho GV, Omori SA, Bruckner S, Arden K, Castrillon DH, DePinho RA, Rickert RC. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol. 2008 Dec; 9(12):1388-98. PMID: 18978794.
        View in: PubMed
      5. Arden K. FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Oncogene. 2008 Apr 7; 27(16):2345-50. PMID: 18391976.
        View in: PubMed
      6. Roeb W, Boyer A, Cavenee WK, Arden K. Guilt by association: PAX3-FOXO1 regulates gene expression through selective destabilization of the EGR1 transcription factor. Cell Cycle. 2008 Apr 1; 7(7):837-41. PMID: 18414034.
        View in: PubMed
      7. Barrera LO, Li Z, Smith AD, Arden K, Cavenee WK, Zhang MQ, Green RD, Ren B. Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs. Genome Res. 2008 Jan; 18(1):46-59. PMID: 18042645.
        View in: PubMed
      8. Roeb W, Boyer A, Cavenee WK, Arden K. PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18085-90. PMID: 17986608.
        View in: PubMed
      9. Arden K. FoxOs in tumor suppression and stem cell maintenance. Cell. 2007 Jan 26; 128(2):235-7. PMID: 17254960.
        View in: PubMed
      10. Finckenstein FG, Davicioni E, Osborn KG, Cavenee WK, Arden K, Anderson MJ. Transgenic mice expressing PAX3-FKHR have multiple defects in muscle development, including ectopic skeletal myogenesis in the developing neural tube. Transgenic Res. 2006 Oct; 15(5):595-614. PMID: 16952014.
        View in: PubMed
      11. Arden K. Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer. Exp Gerontol. 2006 Aug; 41(8):709-17. PMID: 16806782.
        View in: PubMed
      12. Arden K. FoxO: linking new signaling pathways. Mol Cell. 2004 May 21; 14(4):416-8. PMID: 15149589.
        View in: PubMed
      13. Accili D, Arden K. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell. 2004 May 14; 117(4):421-6. PMID: 15137936.
        View in: PubMed
      14. Hosaka T, Biggs WH, Tieu D, Boyer AD, Varki NM, Cavenee WK, Arden K. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci U S A. 2004 Mar 2; 101(9):2975-80. PMID: 14978268.
        View in: PubMed
      15. Stuart RO, Wachsman W, Berry CC, Wang-Rodriguez J, Wasserman L, Klacansky I, Masys D, Arden K, Goodison S, McClelland M, Wang Y, Sawyers A, Kalcheva I, Tarin D, Mercola D. In silico dissection of cell-type-associated patterns of gene expression in prostate cancer. Proc Natl Acad Sci U S A. 2004 Jan 13; 101(2):615-20. PMID: 14722351.
        View in: PubMed
      16. Chen YT, Alpen B, Ono T, Gure AO, Scanlan MA, Biggs WH, Arden K, Nakayama E, Old LJ. Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression. Genomics. 2003 Dec; 82(6):628-36. PMID: 14611804.
        View in: PubMed
      17. Nakae J, Kitamura T, Kitamura Y, Biggs WH, Arden K, Accili D. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev Cell. 2003 Jan; 4(1):119-29. PMID: 12530968.
        View in: PubMed
      18. Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH, Wright CV, White MF, Arden K, Accili D. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J Clin Invest. 2002 Dec; 110(12):1839-47. PMID: 12488434.
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      19. Nakae J, Biggs WH, Kitamura T, Cavenee WK, Wright CV, Arden K, Accili D. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet. 2002 Oct; 32(2):245-53. PMID: 12219087.
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      20. Arden K, Biggs WH. Regulation of the FoxO family of transcription factors by phosphatidylinositol-3 kinase-activated signaling. Arch Biochem Biophys. 2002 Jul 15; 403(2):292-8. PMID: 12139979.
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      21. Johnstone CN, White SJ, Tebbutt NC, Clay FJ, Ernst M, Biggs WH, Viars CS, Czekay S, Arden K, Heath JK. Analysis of the regulation of the A33 antigen gene reveals intestine-specific mechanisms of gene expression. J Biol Chem. 2002 Sep 13; 277(37):34531-9. PMID: 12114523.
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      22. Kawai K, Viars C, Arden K, Tarin D, Urquidi V, Goodison S. Comprehensive karyotyping of the HT-29 colon adenocarcinoma cell line. Genes Chromosomes Cancer. 2002 May; 34(1):1-8. PMID: 11921276.
        View in: PubMed